Showing entry for Mitogen-activated protein kinase kinase kinase 6


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT005376
Protein NameMitogen-activated protein kinase kinase kinase 6
Uniport IdO95382
GeneMAP3K6
Gene Id9064
DomainDUF4071; Pkinase
Pfam PF13281   PF00069  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04010 MAPK signaling pathway
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007257 activation of JUN kinase activity
Biological Process GO:0000186 activation of MAPKK activity
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0007165 signal transduction
molecular function GO:0005524 ATP binding
molecular function GO:0000287 magnesium ion binding
molecular function GO:0004709 MAP kinase kinase kinase activity
molecular function GO:0004672 protein kinase activity
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0346163 BXGD007785 Endometrioid carcinoma ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0876973 BXGD011322 Infectious Lung Disorder Infections; Respiratory Tract Diseases
C1290884 BXGD012198 Inflammatory disorder Pathological Conditions, Signs and Symptoms
C1708349 BXGD013597 Hereditary Diffuse Gastric Cancer Digestive System Diseases; Neoplasms
C2062441 BXGD016897 Influenza A
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0042376 Picropodophyllotoxin 414.13
BXGC0047692 Gefitinib 446.15
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein