Showing entry for Molybdopterin synthase catalytic subunit


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT005413
Protein NameMolybdopterin synthase catalytic subunit
Uniport IdO96007
GeneMOCS2
Gene Id4338
DomainMoaE
Pfam PF02391  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.8 Metabolism of cofactors and vitamins hsa00790 Folate biosynthesis
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
2. Genetic Information Processing 2.3 Folding, sorting and degradation hsa04122 Sulfur relay system
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0032324 molybdopterin cofactor biosynthetic process
Biological Process GO:0006777 Mo-molybdopterin cofactor biosynthetic process
molecular function GO:0030366 molybdopterin synthase activity
cellular component GO:0005829 cytosol
cellular component GO:0019008 molybdopterin synthase complex
cellular component GO:0016607 nuclear speck
cellular component GO:0005654 nucleoplasm
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-196849 Metabolism of water-soluble vitamins and cofactors
R-HSA-196854 Metabolism of vitamins and cofactors
R-HSA-947581 Molybdenum cofactor biosynthesis
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0007789 BXGD000488 Cerebral Palsy Nervous System Diseases
C0013581 BXGD000855 Ectopia Lentis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0017639 BXGD001133 Gliosis Pathological Conditions, Signs and Symptoms
C0020534 BXGD001421 Orbital separation excessive Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0025521 BXGD001876 Inborn Errors of Metabolism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0025958 BXGD001882 Microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0028738 BXGD002081 Nystagmus Eye Diseases; Nervous System Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0151818 BXGD003480 Opisthotonus Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0220988 BXGD004352 Xanthinuria Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0221333 BXGD004441 Hypouricemia Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0221354 BXGD004446 Frontal bossing Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0221355 BXGD004447 Macrocephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0232466 BXGD004543 Feeding difficulties
C0235946 BXGD004789 Cerebral atrophy Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0268119 BXGD005821 Combined molybdoflavoprotein enzyme deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0344482 BXGD007678 Hypoplasia of corpus callosum Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0426970 BXGD008598 Spastic Quadriplegia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0456070 BXGD008863 Growth delay
C0752304 BXGD010711 Hypoxic-Ischemic Encephalopathy Nervous System Diseases; Cardiovascular Diseases
C0878575 BXGD011372 Peripheral demyelination Nervous System Diseases
C1531647 BXGD013301 Cerebral ventriculomegaly Nervous System Diseases
C1827700 BXGD013777 Luxation of lens Eye Diseases
C1832338 BXGD013829 Axonal loss
C1836047 BXGD014074 Long face
C1836543 BXGD014130 Thick vermilion border
C1848431 BXGD014924 Xanthine nephrolithiasis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1854114 BXGD015383 Short nose
C1854988 BXGD015445 Molybdenum Cofactor Deficiency, Complementation Group A Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C1854989 BXGD015446 Molybdenum Cofactor Deficiency, Complementation Group B Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C1865014 BXGD016282 Long philtrum
C1866231 BXGD016388 Full cheeks
C1963184 BXGD016688 Nystagmus, CTCAE 3.0
C3278923 BXGD018748 Dilated ventricles (finding)
C3806442 BXGD019510 Myoclonic spasms Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C3806447 BXGD019511 Increased urinary taurine
C3810487 BXGD019661 Increased urinary hypoxanthine
C4554036 BXGD023557 Nystagmus, CTCAE 5.0
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein