Showing entry for Hypoxic-Ischemic Encephalopathy


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD010711
Disease NameHypoxic-Ischemic Encephalopathy
Disease CUI IdC0752304
MeSH Codes C10   C14  
Disease Class NameNervous System Diseases; Cardiovascular Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O75460 BXGT005127 Serine/threonine-protein kinase/endoribonuclease IRE1 2081 reviewed Kinase
O94759 BXGT005327 Transient receptor potential cation channel subfamily M member 2 7226 reviewed Ion channel
O96007 BXGT005413 Molybdopterin synthase catalytic subunit 4338 reviewed
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02144 BXGT005853 Myoglobin 4151 reviewed
P02461 BXGT005880 Collagen alpha-1(III) chain 1281 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02774 BXGT005959 Vitamin D-binding protein 2638 reviewed Transporter
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04070 BXGT006143 Vitamin K-dependent protein C 5624 reviewed Enzyme
P04150 BXGT006154 Glucocorticoid receptor 2908 reviewed Nuclear receptor
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P04271 BXGT006177 Protein S100-B 6285 reviewed Calcium-binding protein
P04731 BXGT006251 Metallothionein-1A 4489 reviewed
P04732 BXGT006252 Metallothionein-1E 4493 reviewed
P04733 BXGT006253 Metallothionein-1F 4494 reviewed
P04792 BXGT006264 Heat shock protein beta-1 3315 reviewed
P05164 BXGT006333 Myeloperoxidase 4353 reviewed Enzyme
P05230 BXGT006344 Fibroblast growth factor 1 2246 reviewed Signaling
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06396 BXGT006435 Gelsolin 2934 reviewed Cellular structure
P07203 BXGT006566 Glutathione peroxidase 1 2876 reviewed Enzyme
P07438 BXGT006625 Metallothionein-1B 4490 reviewed
P08397 BXGT006768 Porphobilinogen deaminase 3145 reviewed Enzyme
P09104 BXGT006856 Gamma-enolase 2026 reviewed Enzyme
P09429 BXGT006889 High mobility group protein B1 3146 reviewed Nucleic acid binding
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P09936 BXGT006943 Ubiquitin carboxyl-terminal hydrolase isozyme L1 7345 reviewed Enzyme
P0CG48 BXGT007468 Polyubiquitin-C 7316 reviewed Nucleic acid binding
P0DN79 BXGT007511 Cystathionine beta-synthase-like protein 875 reviewed
P10636 BXGT007596 Microtubule-associated protein tau 4137 reviewed
P11166 BXGT007661 Solute carrier family 2, facilitated glucose transporter member 1 6513 reviewed Transporter
P11169 BXGT007664 Solute carrier family 2, facilitated glucose transporter member 3 6515 reviewed Transporter
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13640 BXGT007935 Metallothionein-1G 4495 reviewed
P14618 BXGT008027 Pyruvate kinase PKM 5315 reviewed Kinase
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P17643 BXGT008323 5,6-dihydroxyindole-2-carboxylic acid oxidase 7306 reviewed Enzyme
P17931 BXGT008356 Galectin-3 3958 reviewed Signaling
P21730 BXGT008687 C5a anaphylatoxin chemotactic receptor 1 728 reviewed G-protein coupled receptor
P23297 BXGT008848 Protein S100-A1 6271 reviewed Calcium-binding protein
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P24298 BXGT008960 Alanine aminotransferase 1 2875 reviewed Enzyme
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P34932 BXGT009772 Heat shock 70 kDa protein 4 3308 reviewed
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35520 BXGT009842 Cystathionine beta-synthase 875 reviewed
P36897 BXGT009941 TGF-beta receptor type-1 7046 reviewed Kinase
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P43004 BXGT010348 Excitatory amino acid transporter 2 6506 reviewed Transporter
P45983 BXGT010494 Mitogen-activated protein kinase 8 5599 reviewed Kinase
P48039 BXGT010607 Melatonin receptor type 1A 4543 reviewed G-protein coupled receptor
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49585 BXGT010712 Choline-phosphate cytidylyltransferase A 5130 reviewed
P49763 BXGT010737 Placenta growth factor 5228 reviewed Signaling
P49841 BXGT010750 Glycogen synthase kinase-3 beta 2932 reviewed Kinase
P51617 BXGT010868 Interleukin-1 receptor-associated kinase 1 3654 reviewed Kinase
P55087 BXGT011105 Aquaporin-4 361 reviewed Ion channel
P60174 BXGT011294 Triosephosphate isomerase 7167 reviewed Enzyme
P62979 BXGT011476 Ubiquitin-40S ribosomal protein S27a 6233 reviewed Nucleic acid binding
P78380 BXGT011841 Oxidized low-density lipoprotein receptor 1 4973 reviewed
P80294 BXGT011890 Metallothionein-1H 4496 reviewed
P80297 BXGT011891 Metallothionein-1X 4501 reviewed
P98170 BXGT012231 E3 ubiquitin-protein ligase XIAP 331 reviewed Enzyme modulator
Q02763 BXGT012667 Angiopoietin-1 receptor 7010 reviewed Kinase
Q13501 BXGT013365 Sequestosome-1 8878 reviewed
Q13705 BXGT013393 Activin receptor type-2B 93 reviewed Kinase
Q14011 BXGT013436 Cold-inducible RNA-binding protein 1153 reviewed Nucleic acid binding
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14457 BXGT013472 Beclin-1 8678 reviewed Enzyme modulator
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q8N339 BXGT018503 Metallothionein-1M 4499 reviewed
Q8NE86 BXGT018552 Calcium uniporter protein, mitochondrial 90550 reviewed Ion channel
Q8NER1 BXGT018556 Transient receptor potential cation channel subfamily V member 1 7442 reviewed Ion channel
Q96D42 BXGT019636 Hepatitis A virus cellular receptor 1 26762 reviewed
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q99572 BXGT019935 P2X purinoceptor 7 5027 reviewed Ion channel
Q9NPG2 BXGT021155 Neuroglobin 58157 reviewed Transporter
Q9NPH2 BXGT021158 Inositol-3-phosphate synthase 1 51477 reviewed
Q9NR96 BXGT021181 Toll-like receptor 9 54106 reviewed
Q9NWZ3 BXGT021239 Interleukin-1 receptor-associated kinase 4 51135 reviewed Kinase
Q9UNS1 BXGT022882 Protein timeless homolog 8914 reviewed
P25054 BXGT022961 Adenomatous polyposis coli protein 324 reviewed
Q9GZQ8 BXGT023414 Microtubule-associated proteins 1A/1B light chain 3B 81631 reviewed Cellular structure
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
Q9Y6M1 BXGT025468 Insulin-like growth factor 2 mRNA-binding protein 2 10644 reviewed Enzyme
Q969H8 BXGT025606 Myeloid-derived growth factor 56005 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease