adisease

Showing entry for Cerebral Palsy

General Disease Information
BXGD Id	BXGD000488
Disease Name	Cerebral Palsy
Disease CUI Id	C0007789
MeSH Codes	C10
Disease Class Name	Nervous System Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0000707
Human Phenotype Ontology Term	Abnormality of the nervous system
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00189	BXGT003891	AP-4 complex subunit mu-1	9179	reviewed	Extracellular structure
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O00329	BXGT003909	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	5293	reviewed	Kinase
O15305	BXGT004152	Phosphomannomutase 2	5373	reviewed	Enzyme
O43157	BXGT004572	Plexin-B1	5364	reviewed
O43255	BXGT004579	E3 ubiquitin-protein ligase SIAH2	6478	reviewed
O60271	BXGT004866	C-Jun-amino-terminal kinase-interacting protein 4	9043	reviewed	Enzyme modulator
O60547	BXGT004881	GDP-mannose 4,6 dehydratase	2762	reviewed	Enzyme
O75874	BXGT005157	Isocitrate dehydrogenase [NADP] cytoplasmic	3417	reviewed
O75914	BXGT005165	Serine/threonine-protein kinase PAK 3	5063	reviewed	Kinase
O95622	BXGT005386	Adenylate cyclase type 5	111	reviewed
O95631	BXGT005387	Netrin-1	9423	reviewed	Enzyme modulator
O96007	BXGT005413	Molybdopterin synthase catalytic subunit	4338	reviewed
P00390	BXGT005526	Glutathione reductase, mitochondrial	2936	reviewed	Enzyme
P00492	BXGT005556	Hypoxanthine-guanine phosphoribosyltransferase	3251	reviewed	Enzyme
P00519	BXGT005570	Tyrosine-protein kinase ABL1	25	reviewed	Kinase
P00734	BXGT005630	Prothrombin	2147	reviewed	Enzyme
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P01270	BXGT005746	Parathyroid hormone	5741	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P02462	BXGT005881	Collagen alpha-1(IV) chain	1282	reviewed
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02766	BXGT005953	Transthyretin	7276	reviewed	Transporter
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P02818	BXGT005969	Osteocalcin	632	reviewed
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P04070	BXGT006143	Vitamin K-dependent protein C	5624	reviewed	Enzyme
P04179	BXGT006163	Superoxide dismutase [Mn], mitochondrial	6648	reviewed	Enzyme
P04350	BXGT006193	Tubulin beta-4A chain	10382	reviewed	Cellular structure
P04792	BXGT006264	Heat shock protein beta-1	3315	reviewed
P05106	BXGT006315	Integrin beta-3	3690	reviewed	Receptor
P05121	BXGT006320	Plasminogen activator inhibitor 1	5054	reviewed	Enzyme modulator
P05187	BXGT006339	Alkaline phosphatase, placental type	250	reviewed	Enzyme
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06401	BXGT006436	Progesterone receptor	5241	reviewed	Nuclear receptor
P07203	BXGT006566	Glutathione peroxidase 1	2876	reviewed	Enzyme
P07359	BXGT006612	Platelet glycoprotein Ib alpha chain	2811	reviewed	Receptor
P07550	BXGT006636	Beta-2 adrenergic receptor	154	reviewed	G-protein coupled receptor
P07711	BXGT006661	Cathepsin L1	1514	reviewed	Enzyme
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08514	BXGT006781	Integrin alpha-IIb	3674	reviewed
P08559	BXGT006788	Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial	5160	reviewed
P08684	BXGT006812	Cytochrome P450 3A4	1576	reviewed	Enzyme
P09769	BXGT006917	Tyrosine-protein kinase Fgr	2268	reviewed	Kinase
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P11226	BXGT007675	Mannose-binding protein C	4153	reviewed	Receptor
P12004	BXGT007766	Proliferating cell nuclear antigen	5111	reviewed	Nucleic acid binding
P13224	BXGT007890	Platelet glycoprotein Ib beta chain	2812	reviewed
P13637	BXGT007933	Sodium/potassium-transporting ATPase subunit alpha-3	478	reviewed	Transporter
P15289	BXGT008102	Arylsulfatase A	410	reviewed	Enzyme
P15428	BXGT008121	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	3248	reviewed
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P16410	BXGT008224	Cytotoxic T-lymphocyte protein 4	1493	reviewed
P17301	BXGT008299	Integrin alpha-2	3673	reviewed
P17936	BXGT008357	Insulin-like growth factor-binding protein 3	3486	reviewed	Enzyme modulator
P20702	BXGT008592	Integrin alpha-X	3687	reviewed
P20711	BXGT008594	Aromatic-L-amino-acid decarboxylase	1644	reviewed
P22303	BXGT008751	Acetylcholinesterase	43	reviewed	Enzyme
P22309	BXGT008753	UDP-glucuronosyltransferase 1-1	54658	reviewed
P22897	BXGT008816	Macrophage mannose receptor 1	4360	reviewed
P23219	BXGT008837	Prostaglandin G/H synthase 1	5742	reviewed	Enzyme
P23246	BXGT008840	Splicing factor, proline- and glutamine-rich	6421	reviewed	Nucleic acid binding
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P29474	BXGT009352	Nitric oxide synthase, endothelial	4846	reviewed
P29475	BXGT009353	Nitric oxide synthase, brain	4842	reviewed
P29965	BXGT009388	CD40 ligand	959	reviewed	Signaling
P30793	BXGT009466	GTP cyclohydrolase 1	2643	reviewed	Enzyme
P35219	BXGT009797	Carbonic anhydrase-related protein	767	reviewed
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P35270	BXGT009807	Sepiapterin reductase	6697	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35475	BXGT009837	Alpha-L-iduronidase	3425	reviewed	Enzyme
P35499	BXGT009839	Sodium channel protein type 4 subunit alpha	6329	reviewed	Ion channel
P35610	BXGT009855	Sterol O-acyltransferase 1	6646	reviewed	Enzyme
P36969	BXGT009949	Phospholipid hydroperoxide glutathione peroxidase	2879	reviewed	Enzyme
P41182	BXGT010231	B-cell lymphoma 6 protein	604	reviewed
P41229	BXGT010239	Lysine-specific demethylase 5C	8242	reviewed
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42338	BXGT010303	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	5291	reviewed	Kinase
P42345	BXGT010304	Serine/threonine-protein kinase mTOR	2475	reviewed	Kinase
P42357	BXGT010306	Histidine ammonia-lyase	3034	reviewed
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P43004	BXGT010348	Excitatory amino acid transporter 2	6506	reviewed	Transporter
P46531	BXGT010526	Neurogenic locus notch homolog protein 1	4851	reviewed
P48735	BXGT010657	Isocitrate dehydrogenase [NADP], mitochondrial	3418	reviewed
P48736	BXGT010658	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	5294	reviewed	Kinase
P49908	BXGT010760	Selenoprotein P	6414	reviewed	Extracellular structure
P52803	BXGT010958	Ephrin-A5	1946	reviewed	Signaling
P55774	BXGT011124	C-C motif chemokine 18	6362	reviewed	Signaling
P60568	BXGT011315	Interleukin-2	3558	reviewed
P61073	BXGT011352	C-X-C chemokine receptor type 4	7852	reviewed	G-protein coupled receptor
P81605	BXGT011954	Dermcidin	117159	reviewed
P98155	BXGT012226	Very low-density lipoprotein receptor	7436	reviewed
P98164	BXGT012230	Low-density lipoprotein receptor-related protein 2	4036	reviewed
P98170	BXGT012231	E3 ubiquitin-protein ligase XIAP	331	reviewed	Enzyme modulator
Q01668	BXGT012605	Voltage-dependent L-type calcium channel subunit alpha-1D	776	reviewed	Ion channel
Q01959	BXGT012624	Sodium-dependent dopamine transporter	6531	reviewed	Transporter
Q06124	BXGT012856	Tyrosine-protein phosphatase non-receptor type 11	5781	reviewed
Q06609	BXGT012884	DNA repair protein RAD51 homolog 1	5888	reviewed
Q06710	BXGT012887	Paired box protein Pax-8	7849	reviewed
Q07973	BXGT012952	1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	1591	reviewed	Enzyme
Q08AH3	BXGT013015	Acyl-coenzyme A synthetase ACSM2A, mitochondrial	123876	reviewed	Enzyme
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q676U5	BXGT016177	Autophagy-related protein 16-1	55054	reviewed
Q71U36	BXGT016705	Tubulin alpha-1A chain	7846	reviewed	Cellular structure
Q7L266	BXGT016993	Isoaspartyl peptidase/L-asparaginase	80150	reviewed	Enzyme
Q8IVA8	BXGT018342	Glutamate decarboxylase 1 (Brain, 67kDa)	2571	unreviewed
Q8TCU5	BXGT018802	Glutamate receptor ionotropic, NMDA 3A	116443	reviewed	Ion channel
Q8WZ42	BXGT019023	Titin	7273	reviewed	Kinase
Q92769	BXGT019370	Histone deacetylase 2	3066	reviewed	Epigenetic regulator
Q92959	BXGT019400	Solute carrier organic anion transporter family member 2A1	6578	reviewed	Transporter
Q96BI3	BXGT019623	Gamma-secretase subunit APH-1A	51107	reviewed	Enzyme modulator
Q96EQ8	BXGT019652	E3 ubiquitin-protein ligase RNF125	54941	reviewed
Q99259	BXGT019915	Glutamate decarboxylase 1	2571	reviewed	Enzyme
Q99836	BXGT019970	Myeloid differentiation primary response protein MyD88	4615	reviewed	Enzyme modulator
Q9BV79	BXGT020141	Enoyl-[acyl-carrier-protein] reductase, mitochondrial	51102	reviewed
Q9BVA1	BXGT020142	Tubulin beta-2B chain	347733	reviewed
Q9H0A0	BXGT020434	RNA cytidine acetyltransferase	55226	reviewed
Q9H2X9	BXGT020459	Solute carrier family 12 member 5	57468	reviewed	Transporter
Q9NRW4	BXGT021196	Dual specificity protein phosphatase 22	56940	reviewed
Q9UBC3	BXGT021650	DNA (cytosine-5)-methyltransferase 3B	1789	reviewed
Q9UNN8	BXGT021791	Endothelial protein C receptor	10544	reviewed	Enzyme modulator
Q9UQD0	BXGT021811	Sodium channel protein type 8 subunit alpha	6334	reviewed	Ion channel
Q9Y2Q3	BXGT022242	Glutathione S-transferase kappa 1	373156	reviewed
P43146	BXGT022852	Netrin receptor DCC	1630	reviewed
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
Q14678	BXGT023543	KN motif and ankyrin repeat domain-containing protein 1	23189	reviewed
P00395	BXGT023596	Cytochrome c oxidase subunit 1	4512	reviewed	Enzyme
Q9UBP0	BXGT023601	Spastin	6683	reviewed	Cellular structure
Q9H611	BXGT024211	ATP-dependent DNA helicase PIF1	80119	reviewed
P51608	BXGT025073	Methyl-CpG-binding protein 2	4204	reviewed	Epigenetic regulator
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}