adisease

Showing entry for Long philtrum

General Disease Information
BXGD Id	BXGD016282
Disease Name	Long philtrum
Disease CUI Id	C1865014
MeSH Codes
Disease Class Name
Semantic Type	Finding
Human Phenotype Ontology Id	HP:0000152
Human Phenotype Ontology Term	Abnormality of head or neck
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
A5YKK6	BXGT001378	CCR4-NOT transcription complex subunit 1	23019	reviewed	Transcription factor
O00571	BXGT003938	ATP-dependent RNA helicase DDX3X	1654	reviewed
O14764	BXGT004094	Gamma-aminobutyric acid receptor subunit delta	2563	reviewed	Ion channel
O14770	BXGT004095	Homeobox protein Meis2	4212	reviewed	Enzyme
O14936	BXGT004114	Peripheral plasma membrane protein CASK	8573	reviewed	Kinase
O15146	BXGT004131	Muscle, skeletal receptor tyrosine-protein kinase	4593	reviewed	Kinase
O15305	BXGT004152	Phosphomannomutase 2	5373	reviewed	Enzyme
O15357	BXGT004156	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2	3636	reviewed
O43318	BXGT004586	Mitogen-activated protein kinase kinase kinase 7	6885	reviewed	Kinase
O60488	BXGT004878	Long-chain-fatty-acid--CoA ligase 4	2182	reviewed	Enzyme
O60566	BXGT004884	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta	701	reviewed	Kinase
O60568	BXGT004885	Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3	8985	reviewed	Enzyme
O60706	BXGT004896	ATP-binding cassette sub-family C member 9	10060	reviewed	Transporter
O75147	BXGT005102	Obscurin-like protein 1	23363	reviewed
O75530	BXGT005135	Polycomb protein EED	8726	reviewed
O75899	BXGT005161	Gamma-aminobutyric acid type B receptor subunit 2	9568	reviewed	G-protein coupled receptor
O75909	BXGT005163	Cyclin-K	8812	reviewed	Enzyme modulator
O75914	BXGT005165	Serine/threonine-protein kinase PAK 3	5063	reviewed	Kinase
O76039	BXGT005171	Cyclin-dependent kinase-like 5	6792	reviewed	Kinase
O96007	BXGT005413	Molybdopterin synthase catalytic subunit	4338	reviewed
P00439	BXGT005539	Phenylalanine-4-hydroxylase	5053	reviewed
P01111	BXGT005731	GTPase NRas	4893	reviewed	Enzyme modulator
P01112	BXGT005732	GTPase HRas	3265	reviewed	Enzyme modulator
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P01308	BXGT005749	Insulin	3630	reviewed
P02458	BXGT005879	Collagen alpha-1(II) chain	1280	reviewed
P06753	BXGT006498	Tropomyosin alpha-3 chain	7170	reviewed	Cellular structure
P07437	BXGT006624	Tubulin beta chain	203068	reviewed	Cellular structure
P07510	BXGT006631	Acetylcholine receptor subunit gamma	1146	reviewed	Ion channel
P08069	BXGT006723	Insulin-like growth factor 1 receptor	3480	reviewed	Kinase
P08559	BXGT006788	Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial	5160	reviewed
P10721	BXGT007605	Mast/stem cell growth factor receptor Kit	3815	reviewed	Kinase
P11362	BXGT007693	Fibroblast growth factor receptor 1	2260	reviewed	Kinase
P12643	BXGT007830	Bone morphogenetic protein 2	650	reviewed	Signaling
P13224	BXGT007890	Platelet glycoprotein Ib beta chain	2812	reviewed
P14678	BXGT008038	Small nuclear ribonucleoprotein-associated proteins B and B'	6628	reviewed	Nucleic acid binding
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P16435	BXGT008226	NADPH--cytochrome P450 reductase	5447	reviewed
P21675	BXGT008678	Transcription initiation factor TFIID subunit 1	6872	reviewed	Kinase
P21802	BXGT008691	Fibroblast growth factor receptor 2	2263	reviewed	Kinase
P21964	BXGT008714	Catechol O-methyltransferase	1312	reviewed	Enzyme
P22314	BXGT008755	Ubiquitin-like modifier-activating enzyme 1	7317	reviewed	Enzyme
P22681	BXGT008795	E3 ubiquitin-protein ligase CBL	867	reviewed	Enzyme
P27635	BXGT009194	60S ribosomal protein L10	6134	reviewed	Nucleic acid binding
P30566	BXGT009446	Adenylosuccinate lyase	158	reviewed	Enzyme
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P35555	BXGT009845	Fibrillin-1	2200	reviewed	Calcium-binding protein
P35557	BXGT009846	Glucokinase	2645	reviewed	Kinase
P36507	BXGT009923	Dual specificity mitogen-activated protein kinase kinase 2	5605	reviewed	Kinase
P42345	BXGT010304	Serine/threonine-protein kinase mTOR	2475	reviewed	Kinase
P50052	BXGT010768	Type-2 angiotensin II receptor	186	reviewed	G-protein coupled receptor
P51531	BXGT010851	Probable global transcription activator SNF2L2	6595	reviewed	Epigenetic regulator
P51812	BXGT010893	Ribosomal protein S6 kinase alpha-3	6197	reviewed	Kinase
P52732	BXGT010948	Kinesin-like protein KIF11	3832	reviewed	Cellular structure
P53667	BXGT011008	LIM domain kinase 1	3984	reviewed	Kinase
P55201	BXGT011109	Peregrin	7862	reviewed
P58400	BXGT011235	Neurexin-1-beta	9378	reviewed
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P60953	BXGT011342	Cell division control protein 42 homolog	998	reviewed	Enzyme modulator
P63261	BXGT011512	Actin, cytoplasmic 2	71	reviewed	Cellular structure
P68133	BXGT011578	Actin, alpha skeletal muscle	58	reviewed	Cellular structure
P98160	BXGT012228	Basement membrane-specific heparan sulfate proteoglycan core protein	3339	reviewed	Enzyme modulator
Q00610	BXGT012539	Clathrin heavy chain 1	1213	reviewed	Transporter
Q01968	BXGT012626	Inositol polyphosphate 5-phosphatase OCRL-1	4952	reviewed	Enzyme
Q01974	BXGT012628	Tyrosine-protein kinase transmembrane receptor ROR2	4920	reviewed	Kinase
Q02750	BXGT012662	Dual specificity mitogen-activated protein kinase kinase 1	5604	reviewed	Kinase
Q03164	BXGT012700	Histone-lysine N-methyltransferase 2A	4297	reviewed
Q03431	BXGT012714	Parathyroid hormone/parathyroid hormone-related peptide receptor	5745	reviewed	G-protein coupled receptor
Q03468	BXGT012716	DNA excision repair protein ERCC-6	2074	reviewed
Q04721	BXGT012777	Neurogenic locus notch homolog protein 2	4853	reviewed
Q09428	BXGT013036	ATP-binding cassette sub-family C member 8	6833	reviewed	Transporter
Q13303	BXGT013336	Voltage-gated potassium channel subunit beta-2	8514	reviewed	Ion channel
Q13394	BXGT013347	Putative nucleotidyltransferase MAB21L1	4081	reviewed
Q13555	BXGT013375	Calcium/calmodulin-dependent protein kinase type II subunit gamma	818	reviewed	Kinase
Q14332	BXGT013462	Frizzled-2	2535	reviewed	G-protein coupled receptor
Q14654	BXGT013495	ATP-sensitive inward rectifier potassium channel 11	3767	reviewed	Ion channel
Q14683	BXGT013500	Structural maintenance of chromosomes protein 1A	8243	reviewed
Q15022	BXGT013523	Polycomb protein SUZ12	23512	reviewed	Nucleic acid binding
Q15131	BXGT013545	Cyclin-dependent kinase 10	8558	reviewed	Kinase
Q15652	BXGT013587	Probable JmjC domain-containing histone demethylation protein 2C	221037	reviewed
Q15842	BXGT013607	ATP-sensitive inward rectifier potassium channel 8	3764	reviewed	Ion channel
Q15910	BXGT013612	Histone-lysine N-methyltransferase EZH2	2146	reviewed	Epigenetic regulator
Q6NUK1	BXGT016429	Calcium-binding mitochondrial carrier protein SCaMC-1	29957	reviewed	Transporter
Q8NCM8	BXGT018548	Cytoplasmic dynein 2 heavy chain 1	79659	reviewed	Enzyme
Q8NFD5	BXGT018560	AT-rich interactive domain-containing protein 1B	57492	reviewed
Q8TD19	BXGT018804	Serine/threonine-protein kinase Nek9	91754	reviewed	Kinase
Q8WWQ0	BXGT019003	PH-interacting protein	55023	reviewed	Epigenetic regulator
Q92796	BXGT019376	Disks large homolog 3	1741	reviewed
Q96C36	BXGT019631	Pyrroline-5-carboxylate reductase 2	29920	reviewed
Q9BY41	BXGT020180	Histone deacetylase 8	55869	reviewed	Epigenetic regulator
Q9H4W6	BXGT020478	Transcription factor COE3	253738	reviewed
Q9H6X2	BXGT020486	Anthrax toxin receptor 1	84168	reviewed	Receptor
Q9NSE4	BXGT021207	Isoleucine--tRNA ligase, mitochondrial	55699	reviewed	Enzyme
Q9NZN1	BXGT021279	Interleukin-1 receptor accessory protein-like 1	11141	reviewed	Receptor
Q9UBM7	BXGT021657	7-dehydrocholesterol reductase	1717	reviewed	Enzyme
Q9UHX1	BXGT021707	Poly(U)-binding-splicing factor PUF60	22827	reviewed
Q9UM47	BXGT021772	Neurogenic locus notch homolog protein 3	4854	reviewed
Q9UPT6	BXGT021801	C-Jun-amino-terminal kinase-interacting protein 3	23162	reviewed	Enzyme modulator
Q9Y223	BXGT022207	Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase	10020	reviewed	Enzyme
Q9Y263	BXGT022220	Phospholipase A-2-activating protein	9373	reviewed	Enzyme modulator
Q9Y2I2	BXGT022236	Netrin-G1	22854	reviewed	Enzyme modulator
Q9Y2Z4	BXGT022251	Tyrosine--tRNA ligase, mitochondrial	51067	reviewed	Enzyme
Q9Y606	BXGT022312	tRNA pseudouridine synthase A	80324	reviewed	Enzyme
Q9Y5W7	BXGT022783	Sorting nexin-14	57231	reviewed	Enzyme modulator
P25054	BXGT022961	Adenomatous polyposis coli protein	324	reviewed
Q01543	BXGT023137	Friend leukemia integration 1 transcription factor	2313	reviewed	Transcription factor
Q59FF6	BXGT023693	Excision repair cross-complementing rodent repair deficiency, complementation group 6 variant	2074	unreviewed
Q96L73	BXGT024676	Histone-lysine N-methyltransferase, H3 lysine-36 specific	64324	reviewed	Epigenetic regulator
Q13635	BXGT024910	Protein patched homolog 1	5727	reviewed
P51608	BXGT025073	Methyl-CpG-binding protein 2	4204	reviewed	Epigenetic regulator
Q96DA2	BXGT025522	Ras-related protein Rab-39B	116442	reviewed
P35250	BXGT025854	Replication factor C subunit 2	5982	reviewed	Enzyme
Q9UQE7	BXGT025899	Structural maintenance of chromosomes protein 3	9126	reviewed
Q8WXI2	BXGT026145	Connector enhancer of kinase suppressor of ras 2	22866	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}