Showing entry for Immunoglobulin J chain


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT005774
Protein NameImmunoglobulin J chain
Uniport IdP01591
GeneJCHAIN
Gene Id3512
DomainIg_J_chain
Pfam PF15097  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0002250 adaptive immune response
Biological Process GO:0019731 antibacterial humoral response
Biological Process GO:0003094 glomerular filtration
Biological Process GO:0006959 humoral immune response
Biological Process GO:0006955 immune response
Biological Process GO:0045087 innate immune response
Biological Process GO:0050900 leukocyte migration
Biological Process GO:0060267 positive regulation of respiratory burst
Biological Process GO:0065003 protein-containing complex assembly
Biological Process GO:0006898 receptor-mediated endocytosis
Biological Process GO:0001895 retina homeostasis
molecular function GO:0003823 antigen binding
molecular function GO:0019862 IgA binding
molecular function GO:0034987 immunoglobulin receptor binding
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0030674 protein-macromolecule adaptor activity
cellular component GO:0072562 blood microparticle
cellular component GO:0071750 dimeric IgA immunoglobulin complex
cellular component GO:0070062 extracellular exosome
cellular component GO:0005576 extracellular region
cellular component GO:0005615 extracellular space
cellular component GO:0071748 monomeric IgA immunoglobulin complex
cellular component GO:0071756 pentameric IgM immunoglobulin complex
cellular component GO:0071752 secretory dimeric IgA immunoglobulin complex
cellular component GO:0071751 secretory IgA immunoglobulin complex
Reactome
Pathway Id Pathway Name
R-HSA-109582 Hemostasis
R-HSA-202733 Cell surface interactions at the vascular wall
R-HSA-2168880 Scavenging of heme from plasma
R-HSA-2173782 Binding and Uptake of Ligands by Scavenger Receptors
R-HSA-5653656 Vesicle-mediated transport
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0011615 BXGD000738 Dermatitis, Atopic Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases; Immune System Diseases
C0013595 BXGD000858 Eczema Skin and Connective Tissue Diseases
C0017661 BXGD001139 IGA Glomerulonephritis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Immune System Diseases
C0023890 BXGD001713 Liver Cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0031099 BXGD002282 Periodontitis Stomatognathic Diseases
C0079731 BXGD003087 B-Cell Lymphomas Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0079744 BXGD003090 Diffuse Large B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0239946 BXGD005010 Fibrosis, Liver Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0279584 BXGD006641 Childhood B Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0279593 BXGD006644 Adult B Acute Lymphoblastic Leukemia
C0349636 BXGD007941 Pre B-cell acute lymphoblastic leukemia
C1292754 BXGD012227 Mediastinal (Thymic) Large B-Cell Lymphoma Neoplasms; Respiratory Tract Diseases; Immune System Diseases; Hemic and Lymphatic Diseases
C1292769 BXGD012230 Precursor B-cell lymphoblastic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1321547 BXGD012435 T-cell/histiocyte rich large B-cell lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332201 BXGD012502 Adult Diffuse Large B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332210 BXGD012505 Adult Nodular Lymphocyte Predominant Hodgkin Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1332985 BXGD012573 Childhood Nodular Lymphocyte Predominant Hodgkin Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1333064 BXGD012587 Classical Hodgkin's Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1334968 BXGD012749 Nodular Lymphocyte Predominant Hodgkin Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1623038 BXGD013475 Cirrhosis Pathological Conditions, Signs and Symptoms
C2347747 BXGD017040 Adult Classical Hodgkin Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002682 Zinc 65.41
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein