adisease

Showing entry for Periodontitis

General Disease Information
BXGD Id	BXGD002282
Disease Name	Periodontitis
Disease CUI Id	C0031099
MeSH Codes	C07
Disease Class Name	Stomatognathic Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0002715 HP:0000152
Human Phenotype Ontology Term	Abnormality of the immune system; Abnormality of head or neck
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00148	BXGT003884	ATP-dependent RNA helicase DDX39A	10212	reviewed
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O00329	BXGT003909	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	5293	reviewed	Kinase
O14684	BXGT004082	Prostaglandin E synthase	9536	reviewed
O14727	BXGT004084	Apoptotic protease-activating factor 1	317	reviewed
O14746	BXGT004091	Telomerase reverse transcriptase	7015	reviewed	Enzyme
O14786	BXGT004099	Neuropilin-1	8829	reviewed
O14788	BXGT004100	Tumor necrosis factor ligand superfamily member 11	8600	reviewed	Signaling
O14842	BXGT004106	Free fatty acid receptor 1	2864	reviewed	G-protein coupled receptor
O15379	BXGT004159	Histone deacetylase 3	8841	reviewed	Epigenetic regulator
O15389	BXGT004161	Sialic acid-binding Ig-like lectin 5	8778	reviewed	Receptor
O15392	BXGT004162	Baculoviral IAP repeat-containing protein 5	332	reviewed	Enzyme modulator
O15455	BXGT004171	Toll-like receptor 3	7098	reviewed	Receptor
O15553	BXGT004181	Pyrin	4210	reviewed
O43854	BXGT004630	EGF-like repeat and discoidin I-like domain-containing protein 3	10085	reviewed	Enzyme
O43897	BXGT004633	Tolloid-like protein 1	7092	reviewed
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O60760	BXGT004899	Hematopoietic prostaglandin D synthase	27306	reviewed
O75015	BXGT005095	Low affinity immunoglobulin gamma Fc region receptor III-B	2215	reviewed	Cell adhesion
O75469	BXGT005128	Nuclear receptor subfamily 1 group I member 2	8856	reviewed	Nuclear receptor
O94907	BXGT005340	Dickkopf-related protein 1	22943	reviewed
O95631	BXGT005387	Netrin-1	9423	reviewed	Enzyme modulator
O95644	BXGT005389	Nuclear factor of activated T-cells, cytoplasmic 1	4772	reviewed	Transcription factor
P00491	BXGT005555	Purine nucleoside phosphorylase	4860	reviewed	Enzyme
P00736	BXGT005632	Complement C1r subcomponent	715	reviewed	Enzyme
P00747	BXGT005639	Plasminogen	5340	reviewed	Enzyme
P00749	BXGT005641	Urokinase-type plasminogen activator	5328	reviewed	Enzyme
P00797	BXGT005658	Renin	5972	reviewed	Enzyme
P00813	BXGT005667	Adenosine deaminase	100	reviewed	Enzyme
P01019	BXGT005717	Angiotensinogen	183	reviewed	Enzyme modulator
P01024	BXGT005719	Complement C3	718	reviewed	Enzyme modulator
P01031	BXGT005720	Complement C5	727	reviewed	Enzyme modulator
P01100	BXGT005727	Proto-oncogene c-Fos	2353	reviewed	Transcription factor
P01130	BXGT005735	Low-density lipoprotein receptor	3949	reviewed
P01133	BXGT005736	Pro-epidermal growth factor	1950	reviewed
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01138	BXGT005738	Beta-nerve growth factor	4803	reviewed	Signaling
P01270	BXGT005746	Parathyroid hormone	5741	reviewed
P01275	BXGT005747	Glucagon	2641	reviewed
P01303	BXGT005748	Pro-neuropeptide Y	4852	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01574	BXGT005768	Interferon beta	3456	reviewed
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01589	BXGT005773	Interleukin-2 receptor subunit alpha	3559	reviewed	Receptor
P01591	BXGT005774	Immunoglobulin J chain	3512	reviewed
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P02461	BXGT005880	Collagen alpha-1(III) chain	1281	reviewed
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02675	BXGT005916	Fibrinogen beta chain	2244	reviewed	Signaling
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02749	BXGT005941	Beta-2-glycoprotein 1	350	reviewed
P02751	BXGT005943	Fibronectin	2335	reviewed	Signaling
P02753	BXGT005945	Retinol-binding protein 4	5950	reviewed	Transporter
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P02774	BXGT005959	Vitamin D-binding protein	2638	reviewed	Transporter
P02786	BXGT005961	Transferrin receptor protein 1	7037	reviewed	Enzyme
P02788	BXGT005963	Lactotransferrin	4057	reviewed	Enzyme
P02818	BXGT005969	Osteocalcin	632	reviewed
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P03956	BXGT006120	Interstitial collagenase	4312	reviewed	Enzyme
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P04083	BXGT006147	Annexin A1	301	reviewed
P04179	BXGT006163	Superoxide dismutase [Mn], mitochondrial	6648	reviewed	Enzyme
P04271	BXGT006177	Protein S100-B	6285	reviewed	Calcium-binding protein
P04278	BXGT006182	Sex hormone-binding globulin	6462	reviewed
P04629	BXGT006239	High affinity nerve growth factor receptor	4914	reviewed	Kinase
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P04731	BXGT006251	Metallothionein-1A	4489	reviewed
P04792	BXGT006264	Heat shock protein beta-1	3315	reviewed
P04798	BXGT006265	Cytochrome P450 1A1	1543	reviewed	Enzyme
P05067	BXGT006306	Amyloid-beta precursor protein	351	reviewed	Enzyme modulator
P05091	BXGT006312	Aldehyde dehydrogenase, mitochondrial	217	reviewed	Enzyme
P05107	BXGT006316	Integrin beta-2	3689	reviewed	Receptor
P05109	BXGT006318	Protein S100-A8	6279	reviewed	Calcium-binding protein
P05120	BXGT006319	Plasminogen activator inhibitor 2	5055	reviewed	Enzyme modulator
P05121	BXGT006320	Plasminogen activator inhibitor 1	5054	reviewed	Enzyme modulator
P05164	BXGT006333	Myeloperoxidase	4353	reviewed	Enzyme
P05181	BXGT006337	Cytochrome P450 2E1	1571	reviewed
P05187	BXGT006339	Alkaline phosphatase, placental type	250	reviewed	Enzyme
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P06126	BXGT006412	T-cell surface glycoprotein CD1a	909	reviewed
P06702	BXGT006476	Protein S100-A9	6280	reviewed	Calcium-binding protein
P06731	BXGT006488	Carcinoembryonic antigen-related cell adhesion molecule 5	1048	reviewed
P06733	BXGT006490	Alpha-enolase	2023	reviewed	Enzyme
P06748	BXGT006497	Nucleophosmin	4869	reviewed	Chaperone
P06753	BXGT006498	Tropomyosin alpha-3 chain	7170	reviewed	Cellular structure
P07101	BXGT006547	Tyrosine 3-monooxygenase	7054	reviewed
P07203	BXGT006566	Glutathione peroxidase 1	2876	reviewed	Enzyme
P07225	BXGT006572	Vitamin K-dependent protein S	5627	reviewed
P07333	BXGT006602	Macrophage colony-stimulating factor 1 receptor	1436	reviewed	Kinase
P07550	BXGT006636	Beta-2 adrenergic receptor	154	reviewed	G-protein coupled receptor
P07741	BXGT006666	Adenine phosphoribosyltransferase	353	reviewed
P07996	BXGT006710	Thrombospondin-1	7057	reviewed
P08047	BXGT006720	Transcription factor Sp1	6667	reviewed	Nucleic acid binding
P08246	BXGT006756	Neutrophil elastase	1991	reviewed	Enzyme
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08254	BXGT006758	Stromelysin-1	4314	reviewed	Enzyme
P08311	BXGT006762	Cathepsin G	1511	reviewed	Enzyme
P08473	BXGT006773	Neprilysin	4311	reviewed	Enzyme
P08581	BXGT006794	Hepatocyte growth factor receptor	4233	reviewed	Kinase
P08588	BXGT006795	Beta-1 adrenergic receptor	153	reviewed	G-protein coupled receptor
P08637	BXGT006802	Low affinity immunoglobulin gamma Fc region receptor III-A	2214	reviewed	Cell adhesion
P08697	BXGT006815	Alpha-2-antiplasmin	5345	reviewed	Enzyme modulator
P08887	BXGT006835	Interleukin-6 receptor subunit alpha	3570	reviewed	Signaling
P08922	BXGT006843	Proto-oncogene tyrosine-protein kinase ROS	6098	reviewed	Kinase
P09038	BXGT006851	Fibroblast growth factor 2	2247	reviewed	Signaling
P09237	BXGT006874	Matrilysin	4316	reviewed	Enzyme
P09238	BXGT006875	Stromelysin-2	4319	reviewed	Enzyme
P09429	BXGT006889	High mobility group protein B1	3146	reviewed	Nucleic acid binding
P09488	BXGT006899	Glutathione S-transferase Mu 1	2944	reviewed
P09601	BXGT006909	Heme oxygenase 1	3162	reviewed
P09871	BXGT006932	Complement C1s subcomponent	716	reviewed	Enzyme
P0DN79	BXGT007511	Cystathionine beta-synthase-like protein	875	reviewed
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10147	BXGT007543	C-C motif chemokine 3	6348	reviewed	Signaling
P10275	BXGT007552	Androgen receptor	367	reviewed	Nuclear receptor
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10747	BXGT007609	T-cell-specific surface glycoprotein CD28	940	reviewed
P10809	BXGT007617	60 kDa heat shock protein, mitochondrial	3329	reviewed
P10909	BXGT007630	Clusterin	1191	reviewed
P11166	BXGT007661	Solute carrier family 2, facilitated glucose transporter member 1	6513	reviewed	Transporter
P11215	BXGT007672	Integrin alpha-M	3684	reviewed
P11226	BXGT007675	Mannose-binding protein C	4153	reviewed	Receptor
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P12004	BXGT007766	Proliferating cell nuclear antigen	5111	reviewed	Nucleic acid binding
P12318	BXGT007799	Low affinity immunoglobulin gamma Fc region receptor II-a	2212	reviewed	Cell adhesion
P12643	BXGT007830	Bone morphogenetic protein 2	650	reviewed	Signaling
P12724	BXGT007837	Eosinophil cationic protein	6037	reviewed
P13497	BXGT007915	Bone morphogenetic protein 1	649	reviewed
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P13501	BXGT007917	C-C motif chemokine 5	6352	reviewed	Signaling
P13569	BXGT007923	Cystic fibrosis transmembrane conductance regulator	1080	reviewed	Ion channel
P13688	BXGT007943	Carcinoembryonic antigen-related cell adhesion molecule 1	634	reviewed
P13929	BXGT007971	Beta-enolase	2027	reviewed	Enzyme
P14151	BXGT007990	L-selectin	6402	reviewed
P14174	BXGT007991	Macrophage migration inhibitory factor	4282	reviewed
P14210	BXGT007994	Hepatocyte growth factor	3082	reviewed	Enzyme
P14672	BXGT008037	Solute carrier family 2, facilitated glucose transporter member 4	6517	reviewed	Transporter
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P14866	BXGT008060	Heterogeneous nuclear ribonucleoprotein L	3191	reviewed
P14921	BXGT008068	Protein C-ets-1	2113	reviewed	Transcription factor
P15090	BXGT008079	Fatty acid-binding protein, adipocyte	2167	reviewed
P15144	BXGT008087	Aminopeptidase N	290	reviewed	Enzyme
P15153	BXGT008090	Ras-related C3 botulinum toxin substrate 2	5880	reviewed	Enzyme modulator
P15328	BXGT008108	Folate receptor alpha	2348	reviewed
P15498	BXGT008133	Proto-oncogene vav	7409	reviewed
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P15813	BXGT008158	Antigen-presenting glycoprotein CD1d	912	reviewed
P16070	BXGT008186	CD44 antigen	960	reviewed
P16109	BXGT008194	P-selectin	6403	reviewed
P16410	BXGT008224	Cytotoxic T-lymphocyte protein 4	1493	reviewed
P16581	BXGT008245	E-selectin	6401	reviewed
P16671	BXGT008255	Platelet glycoprotein 4	948	reviewed	Receptor
P17706	BXGT008330	Tyrosine-protein phosphatase non-receptor type 2	5771	reviewed
P18074	BXGT008374	General transcription and DNA repair factor IIH helicase subunit XPD	2068	reviewed	Enzyme
P18433	BXGT008403	Receptor-type tyrosine-protein phosphatase alpha	5786	reviewed	Enzyme
P18564	BXGT008414	Integrin beta-6	3694	reviewed	Receptor
P18848	BXGT008432	Cyclic AMP-dependent transcription factor ATF-4	468	reviewed
P19113	BXGT008458	Histidine decarboxylase	3067	reviewed
P19320	BXGT008470	Vascular cell adhesion protein 1	7412	reviewed
P19440	BXGT008481	Glutathione hydrolase 1 proenzyme	2678	reviewed	Enzyme
P19793	BXGT008515	Retinoic acid receptor RXR-alpha	6256	reviewed	Nuclear receptor
P19838	BXGT008526	Nuclear factor NF-kappa-B p105 subunit	4790	reviewed	Transcription factor
P20160	BXGT008548	Azurocidin	566	reviewed	Enzyme
P20701	BXGT008591	Integrin alpha-L	3683	reviewed
P21453	BXGT008654	Sphingosine 1-phosphate receptor 1	1901	reviewed	G-protein coupled receptor
P21579	BXGT008665	Synaptotagmin-1	6857	reviewed	Transporter
P21589	BXGT008669	5'-nucleotidase	4907	reviewed	Enzyme
P22894	BXGT008815	Neutrophil collagenase	4317	reviewed	Enzyme
P23297	BXGT008848	Protein S100-A1	6271	reviewed	Calcium-binding protein
P23458	BXGT008868	Tyrosine-protein kinase JAK1	3716	reviewed	Kinase
P24158	BXGT008951	Myeloblastin	5657	reviewed	Enzyme
P24298	BXGT008960	Alanine aminotransferase 1	2875	reviewed	Enzyme
P24593	BXGT008979	Insulin-like growth factor-binding protein 5	3488	reviewed	Enzyme modulator
P25025	BXGT009006	C-X-C chemokine receptor type 2	3579	reviewed	G-protein coupled receptor
P25116	BXGT009025	Proteinase-activated receptor 1	2149	reviewed	G-protein coupled receptor
P25774	BXGT009066	Cathepsin S	1520	reviewed	Enzyme
P25942	BXGT009079	Tumor necrosis factor receptor superfamily member 5	958	reviewed
P26358	BXGT009104	DNA (cytosine-5)-methyltransferase 1	1786	reviewed	Epigenetic regulator
P26447	BXGT009114	Protein S100-A4	6275	reviewed	Calcium-binding protein
P27169	BXGT009161	Serum paraoxonase/arylesterase 1	5444	reviewed
P27695	BXGT009199	DNA-(apurinic or apyrimidinic site) lyase	328	reviewed
P27797	BXGT009206	Calreticulin	811	reviewed	Calcium-binding protein
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P28907	BXGT009301	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	952	reviewed	Enzyme
P29034	BXGT009309	Protein S100-A2	6273	reviewed	Calcium-binding protein
P29320	BXGT009332	Ephrin type-A receptor 3	2042	reviewed	Kinase
P29323	BXGT009334	Ephrin type-B receptor 2	2048	reviewed	Kinase
P29460	BXGT009348	Interleukin-12 subunit beta	3593	reviewed	Signaling
P29466	BXGT009349	Caspase-1	834	reviewed	Enzyme
P29474	BXGT009352	Nitric oxide synthase, endothelial	4846	reviewed
P29965	BXGT009388	CD40 ligand	959	reviewed	Signaling
P30556	BXGT009441	Type-1 angiotensin II receptor	185	reviewed	G-protein coupled receptor
P30711	BXGT009460	Glutathione S-transferase theta-1	2952	reviewed
P30874	BXGT009475	Somatostatin receptor type 2	6752	reviewed	G-protein coupled receptor
P31749	BXGT009574	RAC-alpha serine/threonine-protein kinase	207	reviewed	Kinase
P32119	BXGT009600	Peroxiredoxin-2	7001	reviewed	Enzyme
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35372	BXGT009823	Mu-type opioid receptor	4988	reviewed	G-protein coupled receptor
P35520	BXGT009842	Cystathionine beta-synthase	875	reviewed
P35555	BXGT009845	Fibrillin-1	2200	reviewed	Calcium-binding protein
P35613	BXGT009856	Basigin	682	reviewed
P35869	BXGT009877	Aryl hydrocarbon receptor	196	reviewed	Transcription factor
P35968	BXGT009887	Vascular endothelial growth factor receptor 2	3791	reviewed	Kinase
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P39019	BXGT010082	40S ribosomal protein S19	6223	reviewed	Nucleic acid binding
P39900	BXGT010148	Macrophage metalloelastase	4321	reviewed	Enzyme
P40189	BXGT010164	Interleukin-6 receptor subunit beta	3572	reviewed	Signaling
P41231	BXGT010240	P2Y purinoceptor 2	5029	reviewed	G-protein coupled receptor
P42224	BXGT010286	Signal transducer and activator of transcription 1-alpha/beta	6772	reviewed	Nucleic acid binding
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42338	BXGT010303	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	5291	reviewed	Kinase
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P43220	BXGT010367	Glucagon-like peptide 1 receptor	2740	reviewed	G-protein coupled receptor
P43235	BXGT010368	Cathepsin K	1513	reviewed	Enzyme
P43405	BXGT010386	Tyrosine-protein kinase SYK	6850	reviewed	Kinase
P43490	BXGT010395	Nicotinamide phosphoribosyltransferase	10135	reviewed	Signaling
P45452	BXGT010462	Collagenase 3	4322	reviewed	Enzyme
P46108	BXGT010509	Adapter molecule crk	1398	reviewed
P46937	BXGT010554	Transcriptional coactivator YAP1	10413	reviewed	Enzyme modulator
P47900	BXGT010595	P2Y purinoceptor 1	5028	reviewed	G-protein coupled receptor
P48061	BXGT010616	Stromal cell-derived factor 1	6387	reviewed
P48357	BXGT010627	Leptin receptor	3953	reviewed	Signaling
P48546	BXGT010642	Gastric inhibitory polypeptide receptor	2696	reviewed	G-protein coupled receptor
P48736	BXGT010658	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	5294	reviewed	Kinase
P49763	BXGT010737	Placenta growth factor	5228	reviewed	Signaling
P49767	BXGT010739	Vascular endothelial growth factor C	7424	reviewed	Signaling
P49913	BXGT010761	Cathelicidin antimicrobial peptide	820	reviewed
P50225	BXGT010781	Sulfotransferase 1A1	6817	reviewed
P50750	BXGT010818	Cyclin-dependent kinase 9	1025	reviewed	Kinase
P51575	BXGT010861	P2X purinoceptor 1	5023	reviewed	Ion channel
P51679	BXGT010877	C-C chemokine receptor type 4	1233	reviewed	G-protein coupled receptor
P51681	BXGT010878	C-C chemokine receptor type 5	1234	reviewed	G-protein coupled receptor
P51684	BXGT010880	C-C chemokine receptor type 6	1235	reviewed	G-protein coupled receptor
P53634	BXGT011007	Dipeptidyl peptidase 1	1075	reviewed	Enzyme
P55040	BXGT011099	GTP-binding protein GEM	2669	reviewed
P55085	BXGT011104	Proteinase-activated receptor 2	2150	reviewed	G-protein coupled receptor
P55211	BXGT011111	Caspase-9	842	reviewed	Enzyme
P56373	BXGT011164	P2X purinoceptor 3	5024	reviewed	Ion channel
P59665	BXGT011272	Neutrophil defensin 1	728358	reviewed
P60022	BXGT011285	Beta-defensin 1	1672	reviewed
P60033	BXGT011286	CD81 antigen	975	reviewed
P60568	BXGT011315	Interleukin-2	3558	reviewed
P61011	BXGT011346	Signal recognition particle 54 kDa protein	6729	reviewed	Nucleic acid binding
P61073	BXGT011352	C-X-C chemokine receptor type 4	7852	reviewed	G-protein coupled receptor
P62937	BXGT011471	Peptidyl-prolyl cis-trans isomerase A	5478	reviewed
P68871	BXGT011615	Hemoglobin subunit beta	3043	reviewed
P78504	BXGT011844	Protein jagged-1	182	reviewed
P78536	BXGT011847	Disintegrin and metalloproteinase domain-containing protein 17	6868	reviewed
P82251	BXGT011971	b(0,+)-type amino acid transporter 1	11136	reviewed	Transporter
P98170	BXGT012231	E3 ubiquitin-protein ligase XIAP	331	reviewed	Enzyme modulator
Q01105	BXGT012569	Protein SET	6418	reviewed	Enzyme modulator
Q01968	BXGT012626	Inositol polyphosphate 5-phosphatase OCRL-1	4952	reviewed	Enzyme
Q02643	BXGT012660	Growth hormone-releasing hormone receptor	2692	reviewed	G-protein coupled receptor
Q04206	BXGT012754	Transcription factor p65	5970	reviewed	Transcription factor
Q04721	BXGT012777	Neurogenic locus notch homolog protein 2	4853	reviewed
Q06418	BXGT012875	Tyrosine-protein kinase receptor TYRO3	7301	reviewed	Kinase
Q06830	BXGT012894	Peroxiredoxin-1	5052	reviewed	Enzyme
Q07108	BXGT012919	Early activation antigen CD69	969	reviewed
Q07869	BXGT012945	Peroxisome proliferator-activated receptor alpha	5465	reviewed	Nuclear receptor
Q08554	BXGT012990	Desmocollin-1	1823	reviewed	Cell adhesion
Q09428	BXGT013036	ATP-binding cassette sub-family C member 8	6833	reviewed	Transporter
Q12778	BXGT013263	Forkhead box protein O1	2308	reviewed
Q12918	BXGT013280	Killer cell lectin-like receptor subfamily B member 1	3820	reviewed
Q13155	BXGT013320	Aminoacyl tRNA synthase complex-interacting multifunctional protein 2	7965	reviewed
Q13315	BXGT013339	Serine-protein kinase ATM	472	reviewed	Kinase
Q13478	BXGT013362	Interleukin-18 receptor 1	8809	reviewed	Receptor
Q13489	BXGT013364	Baculoviral IAP repeat-containing protein 3	330	reviewed	Enzyme modulator
Q13501	BXGT013365	Sequestosome-1	8878	reviewed
Q13526	BXGT013369	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	5300	reviewed
Q13838	BXGT013397	Spliceosome RNA helicase DDX39B	7919	reviewed
Q14002	BXGT013433	Carcinoembryonic antigen-related cell adhesion molecule 7	1087	reviewed
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q14289	BXGT013459	Protein-tyrosine kinase 2-beta	2185	reviewed	Kinase
Q14790	BXGT013505	Caspase-8	841	reviewed	Enzyme
Q15063	BXGT013531	Periostin	10631	reviewed	Signaling
Q15078	BXGT013534	Cyclin-dependent kinase 5 activator 1	8851	reviewed	Enzyme modulator
Q15109	BXGT013537	Advanced glycosylation end product-specific receptor	177	reviewed	Receptor
Q15185	BXGT013549	Prostaglandin E synthase 3	10728	reviewed	Chaperone
Q15485	BXGT013574	Ficolin-2	2220	reviewed	Signaling
Q15717	BXGT013589	ELAV-like protein 1	1994	reviewed
Q15848	BXGT013609	Adiponectin	9370	reviewed
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
Q16539	BXGT013634	Mitogen-activated protein kinase 14	1432	reviewed	Kinase
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q16678	BXGT013656	Cytochrome P450 1B1	1545	reviewed	Enzyme
Q16698	BXGT013659	2,4-dienoyl-CoA reductase, mitochondrial	1666	reviewed	Enzyme
Q16769	BXGT013665	Glutaminyl-peptide cyclotransferase	25797	reviewed	Enzyme
Q53H47	BXGT015014	Histone-lysine N-methyltransferase SETMAR	6419	reviewed	Epigenetic regulator
Q5VVQ6	BXGT015888	Ubiquitin thioesterase OTU1	55432	reviewed	Enzyme
Q5VWK5	BXGT015891	Interleukin-23 receptor	149233	reviewed	Signaling
Q6NYC1	BXGT016436	Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6	23210	reviewed	Receptor
Q6ZMJ4	BXGT016628	Interleukin-34	146433	reviewed
Q7Z4J2	BXGT017256	Putative glycosyltransferase 6 domain-containing protein 1	360203	reviewed
Q86TM3	BXGT017607	Probable ATP-dependent RNA helicase DDX53	168400	reviewed
Q8IU54	BXGT018331	Interferon lambda-1	282618	reviewed
Q8IVA8	BXGT018342	Glutamate decarboxylase 1 (Brain, 67kDa)	2571	unreviewed
Q8NB16	BXGT018535	Mixed lineage kinase domain-like protein	197259	reviewed	Kinase
Q8NBP7	BXGT018541	Proprotein convertase subtilisin/kexin type 9	255738	reviewed	Enzyme
Q8TDX7	BXGT018817	Serine/threonine-protein kinase Nek7	140609	reviewed	Kinase
Q92835	BXGT019382	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1	3635	reviewed
Q96AZ6	BXGT019621	Interferon-stimulated gene 20 kDa protein	3669	reviewed
Q96D42	BXGT019636	Hepatitis A virus cellular receptor 1	26762	reviewed
Q96EB6	BXGT019646	NAD-dependent protein deacetylase sirtuin-1	23411	reviewed	Epigenetic regulator
Q96F46	BXGT019656	Interleukin-17 receptor A	23765	reviewed
Q96J66	BXGT019680	ATP-binding cassette sub-family C member 11	85320	reviewed	Transporter
Q96LB1	BXGT019692	Mas-related G-protein coupled receptor member X2	117194	reviewed	G-protein coupled receptor
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q96PD4	BXGT019705	Interleukin-17F	112744	reviewed
Q96RI1	BXGT019727	Bile acid receptor	9971	reviewed	Nuclear receptor
Q99259	BXGT019915	Glutamate decarboxylase 1	2571	reviewed	Enzyme
Q99497	BXGT019926	Protein/nucleic acid deglycase DJ-1	11315	reviewed	Enzyme
Q99572	BXGT019935	P2X purinoceptor 7	5027	reviewed	Ion channel
Q99784	BXGT019961	Noelin	10439	reviewed	Cellular structure
Q99836	BXGT019970	Myeloid differentiation primary response protein MyD88	4615	reviewed	Enzyme modulator
Q9BQ65	BXGT020107	U6 snRNA phosphodiesterase	79650	reviewed
Q9BYF1	BXGT020186	Angiotensin-converting enzyme 2	59272	reviewed	Enzyme
Q9BYW2	BXGT020192	Histone-lysine N-methyltransferase SETD2	29072	reviewed	Epigenetic regulator
Q9BZS1	BXGT020203	Forkhead box protein P3	50943	reviewed
Q9GZX6	BXGT020428	Interleukin-22	50616	reviewed
Q9H4A3	BXGT020473	Serine/threonine-protein kinase WNK1	65125	reviewed	Kinase
Q9H999	BXGT020500	Pantothenate kinase 3	79646	reviewed	Kinase
Q9H9B1	BXGT020501	Histone-lysine N-methyltransferase EHMT1	79813	reviewed	Epigenetic regulator
Q9HC29	BXGT020526	Nucleotide-binding oligomerization domain-containing protein 2	64127	reviewed	Enzyme
Q9NP99	BXGT021148	Triggering receptor expressed on myeloid cells 1	54210	reviewed
Q9NR12	BXGT021174	PDZ and LIM domain protein 7	9260	reviewed	Cellular structure
Q9NR96	BXGT021181	Toll-like receptor 9	54106	reviewed
Q9NR97	BXGT021182	Toll-like receptor 8	51311	reviewed
Q9NT68	BXGT021210	Teneurin-2	57451	reviewed
Q9NYK1	BXGT021258	Toll-like receptor 7	51284	reviewed
Q9NZQ7	BXGT021281	Programmed cell death 1 ligand 1	29126	reviewed	Receptor
Q9UBL9	BXGT021656	P2X purinoceptor 2	22953	reviewed	Ion channel
Q9UM07	BXGT021771	Protein-arginine deiminase type-4	23569	reviewed
Q9Y239	BXGT022213	Nucleotide-binding oligomerization domain-containing protein 1	10392	reviewed	Enzyme
Q9Y251	BXGT022215	Heparanase	10855	reviewed	Enzyme
Q9Y275	BXGT022223	Tumor necrosis factor ligand superfamily member 13B	10673	reviewed
Q9Y2J8	BXGT022237	Protein-arginine deiminase type-2	11240	reviewed
Q9Y572	BXGT022289	Receptor-interacting serine/threonine-protein kinase 3	11035	reviewed	Kinase
Q92482	BXGT022676	Aquaporin-3	360	reviewed	Ion channel
Q9UNS1	BXGT022882	Protein timeless homolog	8914	reviewed
P09622	BXGT023116	Dihydrolipoyl dehydrogenase, mitochondrial	1738	reviewed	Enzyme
P19875	BXGT023294	C-X-C motif chemokine 2	2920	reviewed	Signaling
P31994	BXGT023298	Low affinity immunoglobulin gamma Fc region receptor II-b	2213	reviewed	Cell adhesion
Q9GZQ8	BXGT023414	Microtubule-associated proteins 1A/1B light chain 3B	81631	reviewed	Cellular structure
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
P53539	BXGT023438	Protein fosB	2354	reviewed	Transcription factor
Q13007	BXGT023883	Interleukin-24	11009	reviewed
P12838	BXGT023897	Neutrophil defensin 4	1669	reviewed
P15260	BXGT023924	Interferon gamma receptor 1	3459	reviewed	Receptor
Q9BQQ3	BXGT024065	Golgi reassembly-stacking protein 1	64689	reviewed
Q9BYE2	BXGT024631	Transmembrane protease serine 13	84000	reviewed	Enzyme
P20809	BXGT025043	Interleukin-11	3589	reviewed
Q9BSW2	BXGT025251	EF-hand calcium-binding domain-containing protein 4B	84766	reviewed
P23511	BXGT025343	Nuclear transcription factor Y subunit alpha	4800	reviewed	Nucleic acid binding
Q86SQ9	BXGT025875	Dehydrodolichyl diphosphate synthase complex subunit DHDDS	79947	reviewed	Enzyme
Q9UKU9	BXGT025985	Angiopoietin-related protein 2	23452	reviewed	Signaling
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme
P07320	BXGT026150	Gamma-crystallin D	1421	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}