Showing entry for Complement C1q subcomponent subunit C


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT005939
Protein NameComplement C1q subcomponent subunit C
Uniport IdP02747
GeneC1QC
Gene Id714
DomainC1q; Collagen
Pfam PF00386   PF01391  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.1 Immune system hsa04610 Complement and coagulation cascades
6. Human Diseases 6.4 Neurodegenerative diseases hsa05020 Prion diseases
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05133 Pertussis
6. Human Diseases 6.10 Infectious diseases: Parasitic hsa05142 Chagas disease (American trypanosomiasis)
6. Human Diseases 6.8 Infectious diseases: Bacterial hsa05150 Staphylococcus aureus infection
6. Human Diseases 6.3 Immune diseases hsa05322 Systemic lupus erythematosus
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006956 complement activation
Biological Process GO:0006958 complement activation, classical pathway
Biological Process GO:0006955 immune response
Biological Process GO:0045087 innate immune response
Biological Process GO:0030853 negative regulation of granulocyte differentiation
Biological Process GO:0045650 negative regulation of macrophage differentiation
Biological Process GO:0030449 regulation of complement activation
Biological Process GO:0098883 synapse pruning
cellular component GO:0072562 blood microparticle
cellular component GO:0062023 collagen-containing extracellular matrix
cellular component GO:0005581 collagen trimer
cellular component GO:0005576 extracellular region
cellular component GO:0005615 extracellular space
cellular component GO:0098794 postsynapse
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
R-HSA-166658 Complement cascade
R-HSA-166663 Initial triggering of complement
R-HSA-166786 Creation of C4 and C2 activators
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-173623 Classical antibody-mediated complement activation
R-HSA-977606 Regulation of Complement cascade
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001486 BXGD000056 Adenovirus Infections Infections
C0002726 BXGD000125 Amyloidosis Nutritional and Metabolic Diseases
C0023893 BXGD001716 Liver Cirrhosis, Experimental Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0024131 BXGD001736 Lupus Vulgaris Infections; Skin and Connective Tissue Diseases
C0024138 BXGD001738 Lupus Erythematosus, Discoid Skin and Connective Tissue Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0035372 BXGD002544 Rett Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0202236 BXGD004086 Triglycerides measurement
C0206138 BXGD004158 CREST Syndrome Digestive System Diseases; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases; Cardiovascular Diseases
C0239998 BXGD005012 Recurrent infections Pathological Conditions, Signs and Symptoms; Infections; Musculoskeletal Diseases
C0272242 BXGD006330 Complement deficiency disease Immune System Diseases; Hemic and Lymphatic Diseases
C0340044 BXGD007300 Acute exacerbation of chronic obstructive airways disease Respiratory Tract Diseases
C0409974 BXGD008401 Lupus Erythematosus Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases; Immune System Diseases
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1367654 BXGD012886 Marginal Zone B-Cell Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C1970257 BXGD016826 Decreased serum complement factor I
C2985280 BXGD018223 Blood Protein Measurement
C3150902 BXGD018353 C1q DEFICIENCY
C3160718 BXGD018468 PARKINSON DISEASE, LATE-ONSET
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002616 Copper 63.55
BXGC0002682 Zinc 65.41
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein