Showing entry for PARKINSON DISEASE, LATE-ONSET


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD018468
Disease NamePARKINSON DISEASE, LATE-ONSET
Disease CUI IdC3160718
MeSH Codes   
Disease Class Name
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O15123 BXGT004130 Angiopoietin-2 285 reviewed Signaling
O15527 BXGT004176 N-glycosylase/DNA lyase 4968 reviewed
O43464 BXGT004595 Serine protease HTRA2, mitochondrial 27429 reviewed
O43570 BXGT004601 Carbonic anhydrase 12 771 reviewed
O60260 BXGT004864 E3 ubiquitin-protein ligase parkin 5071 reviewed Enzyme
O75628 BXGT005140 GTP-binding protein REM 1 28954 reviewed
P00326 BXGT005499 Alcohol dehydrogenase 1C 126 reviewed Enzyme
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P00813 BXGT005667 Adenosine deaminase 100 reviewed Enzyme
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01270 BXGT005746 Parathyroid hormone 5741 reviewed
P01275 BXGT005747 Glucagon 2641 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01589 BXGT005773 Interleukin-2 receptor subunit alpha 3559 reviewed Receptor
P02452 BXGT005878 Collagen alpha-1(I) chain 1277 reviewed
P02647 BXGT005908 Apolipoprotein A-I 335 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02747 BXGT005939 Complement C1q subcomponent subunit C 714 reviewed
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P02765 BXGT005952 Alpha-2-HS-glycoprotein 197 reviewed Enzyme modulator
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P03956 BXGT006120 Interstitial collagenase 4312 reviewed Enzyme
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04062 BXGT006140 Lysosomal acid glucosylceramidase 2629 reviewed
P04271 BXGT006177 Protein S100-B 6285 reviewed Calcium-binding protein
P04406 BXGT006207 Glyceraldehyde-3-phosphate dehydrogenase 2597 reviewed Enzyme
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P05090 BXGT006311 Apolipoprotein D 347 reviewed
P05091 BXGT006312 Aldehyde dehydrogenase, mitochondrial 217 reviewed Enzyme
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06276 BXGT006430 Cholinesterase 590 reviewed
P06280 BXGT006433 Alpha-galactosidase A 2717 reviewed
P07101 BXGT006547 Tyrosine 3-monooxygenase 7054 reviewed
P07202 BXGT006565 Thyroid peroxidase 7173 reviewed Enzyme
P08138 BXGT006729 Tumor necrosis factor receptor superfamily member 16 4804 reviewed Receptor
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08235 BXGT006751 Mineralocorticoid receptor 4306 reviewed Nuclear receptor
P08254 BXGT006758 Stromelysin-1 4314 reviewed Enzyme
P09038 BXGT006851 Fibroblast growth factor 2 2247 reviewed Signaling
P09466 BXGT006892 Glycodelin 5047 reviewed Enzyme
P09486 BXGT006897 SPARC 6678 reviewed Signaling
P09488 BXGT006899 Glutathione S-transferase Mu 1 2944 reviewed
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P0DMV8 BXGT007509 Heat shock 70 kDa protein 1A 3304 reviewed
P0DMV9 BXGT007510 Heat shock 70 kDa protein 1B 3304 reviewed
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10635 BXGT007595 Cytochrome P450 2D6 1565 reviewed
P10636 BXGT007596 Microtubule-associated protein tau 4137 reviewed
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13688 BXGT007943 Carcinoembryonic antigen-related cell adhesion molecule 1 634 reviewed
P13726 BXGT007950 Tissue factor 2152 reviewed Receptor
P14416 BXGT008011 D(2) dopamine receptor 1813 reviewed G-protein coupled receptor
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P15289 BXGT008102 Arylsulfatase A 410 reviewed Enzyme
P15529 BXGT008134 Membrane cofactor protein 4179 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P17405 BXGT008304 Sphingomyelin phosphodiesterase 6609 reviewed Enzyme
P19320 BXGT008470 Vascular cell adhesion protein 1 7412 reviewed
P19438 BXGT008480 Tumor necrosis factor receptor superfamily member 1A 7132 reviewed
P21728 BXGT008686 D(1A) dopamine receptor 1812 reviewed G-protein coupled receptor
P21918 BXGT008708 D(1B) dopamine receptor 1816 reviewed G-protein coupled receptor
P21964 BXGT008714 Catechol O-methyltransferase 1312 reviewed Enzyme
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P23975 BXGT008935 Sodium-dependent noradrenaline transporter 6530 reviewed Transporter
P27169 BXGT009161 Serum paraoxonase/arylesterase 1 5444 reviewed
P27338 BXGT009172 Amine oxidase [flavin-containing] B 4129 reviewed
P27361 BXGT009176 Mitogen-activated protein kinase 3 5595 reviewed Kinase
P28223 BXGT009239 5-hydroxytryptamine receptor 2A 3356 reviewed G-protein coupled receptor
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P30793 BXGT009466 GTP cyclohydrolase 1 2643 reviewed Enzyme
P31645 BXGT009558 Sodium-dependent serotonin transporter 6532 reviewed Transporter
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P32119 BXGT009600 Peroxiredoxin-2 7001 reviewed Enzyme
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35462 BXGT009835 D(3) dopamine receptor 1814 reviewed G-protein coupled receptor
P36897 BXGT009941 TGF-beta receptor type-1 7046 reviewed Kinase
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P37840 BXGT010015 Alpha-synuclein 6622 reviewed Transporter
P39060 BXGT010088 Collagen alpha-1(XVIII) chain 80781 reviewed
P41222 BXGT010237 Prostaglandin-H2 D-isomerase 5730 reviewed Enzyme
P41597 BXGT010268 C-C chemokine receptor type 2 729230 reviewed
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P43220 BXGT010367 Glucagon-like peptide 1 receptor 2740 reviewed G-protein coupled receptor
P43354 BXGT010381 Nuclear receptor subfamily 4 group A member 2 4929 reviewed Nuclear receptor
P49281 BXGT010689 Natural resistance-associated macrophage protein 2 4891 reviewed Transporter
P49448 BXGT010709 Glutamate dehydrogenase 2, mitochondrial 2747 reviewed Enzyme
P52758 BXGT010951 2-iminobutanoate/2-iminopropanoate deaminase 10247 reviewed
P54652 BXGT011064 Heat shock-related 70 kDa protein 2 3306 reviewed
P54762 BXGT011076 Ephrin type-B receptor 1 2047 reviewed Kinase
P54803 BXGT011082 Galactocerebrosidase 2581 reviewed
P62258 BXGT011415 14-3-3 protein epsilon 7531 reviewed Chaperone
P63208 BXGT011507 S-phase kinase-associated protein 1 6500 reviewed Enzyme
P78330 BXGT011833 Phosphoserine phosphatase 5723 reviewed Enzyme
P81172 BXGT011935 Hepcidin 57817 reviewed
P98164 BXGT012230 Low-density lipoprotein receptor-related protein 2 4036 reviewed
Q01082 BXGT012567 Spectrin beta chain, non-erythrocytic 1 6711 reviewed
Q01959 BXGT012624 Sodium-dependent dopamine transporter 6531 reviewed Transporter
Q04637 BXGT012771 Eukaryotic translation initiation factor 4 gamma 1 1981 reviewed Nucleic acid binding
Q05940 BXGT012846 Synaptic vesicular amine transporter 6571 reviewed Transporter
Q06787 BXGT012890 Synaptic functional regulator FMR1 2332 reviewed Nucleic acid binding
Q12882 BXGT013276 Dihydropyrimidine dehydrogenase [NADP(+)] 1806 reviewed Enzyme
Q12931 BXGT013282 Heat shock protein 75 kDa, mitochondrial 10131 reviewed Chaperone
Q13148 BXGT013318 TAR DNA-binding protein 43 23435 reviewed
Q13224 BXGT013328 Glutamate receptor ionotropic, NMDA 2B 2904 reviewed Ion channel
Q13427 BXGT013354 Peptidyl-prolyl cis-trans isomerase G 9360 reviewed
Q15077 BXGT013533 P2Y purinoceptor 6 5031 reviewed G-protein coupled receptor
Q15109 BXGT013537 Advanced glycosylation end product-specific receptor 177 reviewed Receptor
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q16568 BXGT013640 Cocaine- and amphetamine-regulated transcript protein 9607 reviewed
Q16637 BXGT013646 Survival motor neuron protein 6607 reviewed Epigenetic regulator
Q30201 BXGT014297 Hereditary hemochromatosis protein 3077 reviewed
Q53EL6 BXGT015008 Programmed cell death protein 4 27250 reviewed Nucleic acid binding
Q59FK2 BXGT015276 Selenocysteine lyase variant 51540 unreviewed
Q5S007 BXGT015650 Leucine-rich repeat serine/threonine-protein kinase 2 120892 reviewed Kinase
Q6N021 BXGT016378 Methylcytosine dioxygenase TET2 54790 reviewed
Q8IXI2 BXGT018361 Mitochondrial Rho GTPase 1 55288 reviewed Enzyme modulator
Q8WTS6 BXGT018986 Histone-lysine N-methyltransferase SETD7 80854 reviewed Epigenetic regulator
Q8WXI8 BXGT019014 C-type lectin domain family 4 member D 338339 reviewed
Q96FE5 BXGT019657 Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 84894 reviewed Receptor
Q96I15 BXGT019674 Selenocysteine lyase 51540 reviewed Enzyme
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q96QK1 BXGT019720 Vacuolar protein sorting-associated protein 35 55737 reviewed Transporter
Q99497 BXGT019926 Protein/nucleic acid deglycase DJ-1 11315 reviewed Enzyme
Q99700 BXGT019949 Ataxin-2 6311 reviewed Nucleic acid binding
Q9BXM7 BXGT020172 Serine/threonine-protein kinase PINK1, mitochondrial 65018 reviewed Kinase
Q9H9B1 BXGT020501 Histone-lysine N-methyltransferase EHMT1 79813 reviewed Epigenetic regulator
Q9NZM3 BXGT021278 Intersectin-2 50618 reviewed Enzyme modulator
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9Y2Q3 BXGT022242 Glutathione S-transferase kappa 1 373156 reviewed
P16284 BXGT022972 Platelet endothelial cell adhesion molecule 5175 reviewed Cell adhesion
Q9UBQ0 BXGT023474 Vacuolar protein sorting-associated protein 29 51699 reviewed Transporter
P07954 BXGT023939 Fumarate hydratase, mitochondrial 2271 reviewed Enzyme
Q8IX03 BXGT024000 Protein KIBRA 23286 reviewed
Q6SZW1 BXGT025034 NAD(+) hydrolase SARM1 23098 reviewed
Q9P121 BXGT025711 Neurotrimin 50863 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease