adisease

Showing entry for CREST Syndrome

General Disease Information
BXGD Id	BXGD004158
Disease Name	CREST Syndrome
Disease CUI Id	C0206138
MeSH Codes	C06 C18 C17 C14
Disease Class Name	Digestive System Diseases; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases; Cardiovascular Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:7 DOID:225
Disease Ontology Class Name	disease of anatomical entity; syndrome
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O60674	BXGT004892	Tyrosine-protein kinase JAK2	3717	reviewed	Kinase
O60911	BXGT004909	Cathepsin L2	1515	reviewed	Enzyme
O75015	BXGT005095	Low affinity immunoglobulin gamma Fc region receptor III-B	2215	reviewed	Cell adhesion
O75030	BXGT005096	Microphthalmia-associated transcription factor	4286	reviewed
P00439	BXGT005539	Phenylalanine-4-hydroxylase	5053	reviewed
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P02746	BXGT005938	Complement C1q subcomponent subunit B	713	reviewed
P02747	BXGT005939	Complement C1q subcomponent subunit C	714	reviewed
P02766	BXGT005953	Transthyretin	7276	reviewed	Transporter
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06241	BXGT006429	Tyrosine-protein kinase Fyn	2534	reviewed	Kinase
P08637	BXGT006802	Low affinity immunoglobulin gamma Fc region receptor III-A	2214	reviewed	Cell adhesion
P08670	BXGT006810	Vimentin	7431	reviewed
P09429	BXGT006889	High mobility group protein B1	3146	reviewed	Nucleic acid binding
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10323	BXGT007557	Acrosin	49	reviewed	Enzyme
P13236	BXGT007891	C-C motif chemokine 4	6351	reviewed
P20273	BXGT008557	B-cell receptor CD22	933	reviewed
P22897	BXGT008816	Macrophage mannose receptor 1	4360	reviewed
P24385	BXGT008965	G1/S-specific cyclin-D1	595	reviewed	Enzyme modulator
P29475	BXGT009353	Nitric oxide synthase, brain	4842	reviewed
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P36222	BXGT009914	Chitinase-3-like protein 1	1116	reviewed
P37023	BXGT009953	Serine/threonine-protein kinase receptor R3	94	reviewed	Kinase
P51684	BXGT010880	C-C chemokine receptor type 6	1235	reviewed	G-protein coupled receptor
P55774	BXGT011124	C-C motif chemokine 18	6362	reviewed	Signaling
P60568	BXGT011315	Interleukin-2	3558	reviewed
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
Q03518	BXGT012723	Antigen peptide transporter 1	6890	reviewed	Transporter
Q16666	BXGT013654	Gamma-interferon-inducible protein 16	3428	reviewed	Transcription factor
Q9HBE5	BXGT020518	Interleukin-21 receptor	50615	reviewed	Receptor
Q9HBX9	BXGT020523	Relaxin receptor 1	59350	reviewed	G-protein coupled receptor
Q8IZA0	BXGT025026	Dyslexia-associated protein KIAA0319-like protein	79932	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}