Showing entry for Epigalocatechin Gallate


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0033310
Compound NameEpigalocatechin Gallate
Structure
FormulaC22H18O11
InchiKeyWMBWREPUVVBILR-WIYYLYMNSA-N
SMILESOc1cc(O)c2c(c1)O[C@@H]([C@@H](C2)OC(=O)c1cc(O)c(c(c1)O)O)c1cc(O)c(c(c1)O)O
InchiInChI=1S/C22H18O11/c23-10-5-12(24)11-7-18(33-22(31)9-3-15(27)20(30)16(28)4-9)21(32-17(11)6-10)8-1-13(25)19(29)14(26)2-8/h1-6,18,21,23-30H,7H2/t18-,21-/m1/s1
IUPAC[(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate
Molecular Weight458.08
Pubchem Id65064
Chembl IdCHEMBL297453
Targets of Information Source
DrugBank DB12116
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
P35869 BXGT009877 Aryl hydrocarbon receptor reviewed Transcription factor AHR investigational -
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 reviewed Epigenetic regulator DNMT1 investigational inhibitor
Q86XF0 BXGT017629 Dihydrofolate reductase 2, mitochondrial reviewed Enzyme DHFR2 investigational -
PDB KDH
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
P63316 BXGT011517 Troponin C, slow skeletal and cardiac muscles reviewed TNNC1 Calcium-binding protein - - - -
P02766 BXGT005953 Transthyretin reviewed TTR Transporter - - - -
Q13526 BXGT013369 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 reviewed PIN1 - - - 21600 -
C3W5S0 BXGT002458 Polymerase acidic protein unreviewed PA - - - - -
J7HDY4 BXGT003738 Beta-fructofuranosidase unreviewed INV - - - - -
Binding DB 50070942
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT022194 Zinc finger protein mex-5 reviewed mex-5 - - - 727
reviewed BXGT016073 Dual specificity tyrosine-phosphorylation-regulated kinase 1A reviewed Dyrk1a 330 - - -
reviewed BXGT013216 Alpha-(1,3)-fucosyltransferase 7 reviewed Enzyme FUT7 - 700 - -
reviewed BXGT013216 Alpha-(1,3)-fucosyltransferase 7 reviewed Enzyme FUT7 - 2200 - -
reviewed BXGT010914 Alpha-(1,3)-fucosyltransferase 6 reviewed Enzyme FUT6 - 1800 - -
reviewed BXGT013217 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 reviewed ST3GAL1 - 27000 - -
reviewed BXGT011847 Disintegrin and metalloproteinase domain-containing protein 17 reviewed ADAM17 - 21000 - -
reviewed BXGT006757 72 kDa type IV collagenase reviewed Enzyme MMP2 - 3700 - -
reviewed BXGT006874 Matrilysin reviewed Enzyme MMP7 - 8300 - -
reviewed BXGT006320 Plasminogen activator inhibitor 1 reviewed Enzyme modulator SERPINE1 - 91 - -
reviewed BXGT006753 Heat shock protein HSP 90-beta reviewed Chaperone HSP90AB1 - 155000 - -
reviewed BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP - 4600 - -
reviewed BXGT010788 Matrix metalloproteinase-14 reviewed Enzyme MMP14 - 6800 - -
reviewed BXGT010694 Fatty acid synthase reviewed Enzyme FASN - 51970 - -
reviewed BXGT011200 Beta-secretase 1 reviewed Enzyme BACE1 - 7.6 - -
reviewed BXGT011200 Beta-secretase 1 reviewed Enzyme BACE1 - 1600 - -
reviewed BXGT009104 DNA (cytosine-5)-methyltransferase 1 reviewed Epigenetic regulator DNMT1 - 500 - -
reviewed BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP - 500 - -
reviewed BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 - 123 - -
reviewed BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 - 124 - -
reviewed BXGT016073 Dual specificity tyrosine-phosphorylation-regulated kinase 1A reviewed Dyrk1a - 330 - -
reviewed BXGT006255 Alpha-amylase 1 reviewed AMY1A - 1400000 - -
reviewed BXGT013038 Histone acetyltransferase p300 reviewed EP300 - 30000 - -
reviewed BXGT019374 CREB-binding protein reviewed CREBBP - 50000 - -
reviewed BXGT019380 Histone acetyltransferase KAT2B reviewed KAT2B - 60000 - -
reviewed BXGT019403 Histone acetyltransferase KAT5 reviewed KAT5 - 70000 - -
reviewed BXGT006874 Matrilysin reviewed Enzyme MMP7 - 21500 - -
reviewed BXGT006757 72 kDa type IV collagenase reviewed Enzyme MMP2 - 9600 - -
reviewed BXGT006794 Hepatocyte growth factor receptor reviewed Kinase MET - 10000 - -
reviewed BXGT006794 Hepatocyte growth factor receptor reviewed Kinase MET 3300 - - -
reviewed BXGT006756 Neutrophil elastase reviewed Enzyme ELANE - 12800 - -
reviewed BXGT013634 Mitogen-activated protein kinase 14 reviewed Kinase MAPK14 - 2210 - -
reviewed BXGT013385 Dual specificity tyrosine-phosphorylation-regulated kinase 1A reviewed Kinase DYRK1A - 13440 - -
reviewed BXGT010917 Squalene monooxygenase reviewed Sqle - 690 - -
reviewed BXGT007320 Enoyl-[acyl-carrier-protein] reductase [NADH] FabI reviewed fabI - 15000 - -
reviewed BXGT007700 Glucose-6-phosphate 1-dehydrogenase reviewed ZWF1 - 250 - -
reviewed BXGT010923 6-phosphogluconate dehydrogenase, decarboxylating reviewed Enzyme PGD - 720 - -
reviewed BXGT008161 CPG DNA methylase reviewed sssIM 28 - - -
reviewed BXGT007788 Fatty acid synthase reviewed FASN - 100000 - -
reviewed BXGT007788 Fatty acid synthase reviewed FASN - 52000 - -
reviewed BXGT004091 Telomerase reverse transcriptase reviewed Enzyme TERT - 1000 - -
reviewed BXGT004091 Telomerase reverse transcriptase reviewed Enzyme TERT - 1080 - -
reviewed BXGT004091 Telomerase reverse transcriptase reviewed Enzyme TERT - 1180 - -
reviewed BXGT005373 Bile salt export pump reviewed Transporter ABCB11 - 214000 - -
reviewed BXGT007596 Microtubule-associated protein tau reviewed MAPT - 1800 - -
reviewed BXGT013369 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 reviewed PIN1 - 20000 - -
reviewed BXGT013385 Dual specificity tyrosine-phosphorylation-regulated kinase 1A reviewed Kinase DYRK1A - 330 - -
reviewed BXGT010286 Signal transducer and activator of transcription 1-alpha/beta reviewed Nucleic acid binding STAT1 - - 700 -
CHEMBL CHEMBL297453
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
Q7ZJM1 BXGT017268 Integrase unreviewed - pol Inhibition '>' 50 %
Q64725 BXGT016130 Tyrosine-protein kinase SYK reviewed - Syk Activity - - -
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency '=' 316 nM
B2RXH2 BXGT002006 Lysine-specific demethylase 4E reviewed - KDM4E Potency '=' 8912 nM
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit reviewed Transcription factor NFKB1 Potency - 12589 nM
Q13627 BXGT013385 Dual specificity tyrosine-phosphorylation-regulated kinase 1A reviewed Kinase DYRK1A IC50 '=' 330 nM
P56817 BXGT011200 Beta-secretase 1 reviewed Enzyme BACE1 Inhibition - - -
O14746 BXGT004091 Telomerase reverse transcriptase reviewed Enzyme TERT Imax '=' 80 %
Q9NPD5 BXGT021151 Solute carrier organic anion transporter family member 1B3 reviewed Transporter SLCO1B3 Inhibition '=' 45 %
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma reviewed Nuclear receptor PPARG Potency - 35481 nM
P56817 BXGT011200 Beta-secretase 1 reviewed Enzyme BACE1 RFU '=' 99 -
Q13627 BXGT013385 Dual specificity tyrosine-phosphorylation-regulated kinase 1A reviewed Kinase DYRK1A IC50 '=' 13440 nM
P56818 BXGT011201 Beta-secretase 1 reviewed - Bace1 Activity '=' 57 %
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 25118 nM
P09237 BXGT006874 Matrilysin reviewed Enzyme MMP7 IC50 '=' 21500 nM
P12276 BXGT007788 Fatty acid synthase reviewed - FASN IC50 '=' 52000 nM
P08581 BXGT006794 Hepatocyte growth factor receptor reviewed Kinase MET Inhibition - - -
P08581 BXGT006794 Hepatocyte growth factor receptor reviewed Kinase MET Ki '=' 3300 nM
P08238 BXGT006753 Heat shock protein HSP 90-beta reviewed Chaperone HSP90AB1 IC50 '=' 155000 nM
P10415 BXGT007567 Apoptosis regulator Bcl-2 reviewed Signaling BCL2 Ki '=' 234 nM
P23219 BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 Inhibition '=' 51 %
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 reviewed Kinase ERBB2 Inhibition '=' 18 %
Q965D5 BXGT019600 Enoyl-acyl-carrier protein reductase unreviewed - fabI IC50 '=' 200 nM
P08246 BXGT006756 Neutrophil elastase reviewed Enzyme ELANE Inhibition '=' 41 %
P24135 BXGT008949 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 reviewed - Plcg2 Activity - - -
P56817 BXGT011200 Beta-secretase 1 reviewed Enzyme BACE1 Inhibition '=' -12 %
P56817 BXGT011200 Beta-secretase 1 reviewed Enzyme BACE1 Inhibition '=' 5 %
P08246 BXGT006756 Neutrophil elastase reviewed Enzyme ELANE IC50 '=' 12800 nM
P15840 BXGT008161 CPG DNA methylase reviewed - sssIM Ki '=' 28 nM
Q965D5 BXGT019600 Enoyl-acyl-carrier protein reductase unreviewed - fabI IC50 '=' 250 nM
Q965D5 BXGT019600 Enoyl-acyl-carrier protein reductase unreviewed - fabI Ki '=' 79 nM
Q72547 BXGT016709 Reverse transcriptase/RNaseH unreviewed - pol IC50 '=' 730 nM
Q965D7 BXGT019602 Beta-hydroxyacyl-ACP dehydratase unreviewed - fabZ IC50 '=' 0 ug.mL-1
P08246 BXGT006756 Neutrophil elastase reviewed Enzyme ELANE Inhibition '=' 63 %
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 14125 nM
G5EF15 BXGT003524 Cytoplasmic zinc-finger protein unreviewed - pos-1 EC50 '=' 5892 nM
O97447 BXGT005436 Putative fructose-1,6-bisphosphate aldolase unreviewed - ald Potency '=' 14091 nM
P42224 BXGT010286 Signal transducer and activator of transcription 1-alpha/beta reviewed Nucleic acid binding STAT1 Kd '=' 700 nM
Q92993 BXGT019403 Histone acetyltransferase KAT5 reviewed - KAT5 IC50 '=' 70000 nM
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 27306 nM
Q96KQ7 BXGT019687 Histone-lysine N-methyltransferase EHMT2 reviewed Epigenetic regulator EHMT2 Potency - 1778 nM
P10686 BXGT007601 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 reviewed - Plcg1 Activity - - -
P10415 BXGT007567 Apoptosis regulator Bcl-2 reviewed Signaling BCL2 Ki '=' 335 nM
P52020 BXGT010917 Squalene monooxygenase reviewed - Sqle IC50 '=' 690 nM
P14618 BXGT008027 Pyruvate kinase PKM reviewed Kinase PKM Potency '=' 3981 nM
P52209 BXGT010923 6-phosphogluconate dehydrogenase, decarboxylating reviewed Enzyme PGD IC50 '=' 720 nM
P08253 BXGT006757 72 kDa type IV collagenase reviewed Enzyme MMP2 IC50 '=' 9600 nM
P08581 BXGT006794 Hepatocyte growth factor receptor reviewed Kinase MET IC50 '=' 10000 nM
P08246 BXGT006756 Neutrophil elastase reviewed Enzyme ELANE Inhibition '=' 78 %
P49327 BXGT010694 Fatty acid synthase reviewed Enzyme FASN IC50 '=' 51970 nM
P46063 BXGT010501 ATP-dependent DNA helicase Q1 reviewed Enzyme RECQL Potency '=' 3162 nM
P00374 BXGT005520 Dihydrofolate reductase reviewed Enzyme DHFR Activity '=' 0 uM
O42275 BXGT004559 Acetylcholinesterase reviewed - ache Inhibition '=' -14 %
P80025 BXGT011867 Lactoperoxidase reviewed - LPO Kcat/Km '=' 43 /uM/s
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 reviewed Kinase ERBB2 Activity - - -
P10828 BXGT007624 Thyroid hormone receptor beta reviewed Nuclear receptor THRB Potency - 28183 nM
P08246 BXGT006756 Neutrophil elastase reviewed Enzyme ELANE Inhibition '=' 26 %
P06746 BXGT006496 DNA polymerase beta reviewed Enzyme POLB Potency '=' 446 nM
Q9F4F7 BXGT020344 4'-phosphopantetheinyl transferase ffp reviewed - ffp Potency '=' 11220 nM
Q965D6 BXGT019601 3-oxoacyl-acyl-carrier protein reductase unreviewed - fabG IC50 '=' 300 nM
P56817 BXGT011200 Beta-secretase 1 reviewed Enzyme BACE1 RFU '=' -6 -
P56817 BXGT011200 Beta-secretase 1 reviewed Enzyme BACE1 RFU '=' 1 -
P56817 BXGT011200 Beta-secretase 1 reviewed Enzyme BACE1 RFU '=' 20 -
Q13627 BXGT013385 Dual specificity tyrosine-phosphorylation-regulated kinase 1A reviewed Kinase DYRK1A Inhibition '=' 47 %
Q965D6 BXGT019601 3-oxoacyl-acyl-carrier protein reductase unreviewed - fabG IC50 '=' 0 ug.mL-1
Q965D7 BXGT019602 Beta-hydroxyacyl-ACP dehydratase unreviewed - fabZ IC50 '=' 400 nM
O14746 BXGT004091 Telomerase reverse transcriptase reviewed Enzyme TERT Ratio IC50 '=' 8 -
O14746 BXGT004091 Telomerase reverse transcriptase reviewed Enzyme TERT Ratio IC50 '=' 10 -
Q9Y6L6 BXGT022334 Solute carrier organic anion transporter family member 1B1 reviewed Transporter SLCO1B1 Inhibition '=' 49 %
P56817 BXGT011200 Beta-secretase 1 reviewed Enzyme BACE1 Inhibition '=' -18 %
P56817 BXGT011200 Beta-secretase 1 reviewed Enzyme BACE1 RFU '=' 26 -
Q8IW41 BXGT018352 MAP kinase-activated protein kinase 5 reviewed Kinase MAPKAPK5 IC50 '=' 1000 nM
P08246 BXGT006756 Neutrophil elastase reviewed Enzyme ELANE Inhibition '=' 71 %
Q99814 BXGT019965 Endothelial PAS domain-containing protein 1 reviewed Transcription factor EPAS1 Activity - - -
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha reviewed Transcription factor HIF1A Activity - - -
Q13627 BXGT013385 Dual specificity tyrosine-phosphorylation-regulated kinase 1A reviewed Kinase DYRK1A Inhibition - - -
P35354 BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 Inhibition '=' 13 %
P56817 BXGT011200 Beta-secretase 1 reviewed Enzyme BACE1 RFU '=' -6 -
P56817 BXGT011200 Beta-secretase 1 reviewed Enzyme BACE1 RFU '=' -2 -
P56817 BXGT011200 Beta-secretase 1 reviewed Enzyme BACE1 IC50 '=' 757 nM
Q965D5 BXGT019600 Enoyl-acyl-carrier protein reductase unreviewed - fabI Ki '=' 186 nM
P56817 BXGT011200 Beta-secretase 1 reviewed Enzyme BACE1 RFU '=' 98 -
P56817 BXGT011200 Beta-secretase 1 reviewed Enzyme BACE1 Inhibition '=' 38 %
Q63470 BXGT016073 Dual specificity tyrosine-phosphorylation-regulated kinase 1A reviewed - Dyrk1a IC50 '=' 330 nM
Q13526 BXGT013369 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 reviewed - PIN1 IC50 '=' 20000 nM
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 reviewed Epigenetic regulator DNMT1 Inhibition '=' 42 %
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 12589 nM
Q72874 BXGT016711 Pol polyprotein unreviewed - pol IC50 - - -
O14746 BXGT004091 Telomerase reverse transcriptase reviewed Enzyme TERT IC50 '=' 1000 nM
P02768 BXGT005955 Serum albumin reviewed Transporter ALB Activity - - -
Q16539 BXGT013634 Mitogen-activated protein kinase 14 reviewed Kinase MAPK14 IC50 '=' 2210 nM
P56817 BXGT011200 Beta-secretase 1 reviewed Enzyme BACE1 RFU '=' -5 -
Q9UIF8 BXGT021718 Bromodomain adjacent to zinc finger domain protein 2B reviewed - BAZ2B Potency - 8912 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Ratio '=' 1 -
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT IC50 '=' 1800 nM
P56817 BXGT011200 Beta-secretase 1 reviewed Enzyme BACE1 RFU '=' 85 -
P56817 BXGT011200 Beta-secretase 1 reviewed Enzyme BACE1 IC50 '=' 1600 nM
P50281 BXGT010788 Matrix metalloproteinase-14 reviewed Enzyme MMP14 IC50 '=' 6800 nM
P10253 BXGT007550 Lysosomal alpha-glucosidase reviewed Enzyme GAA Potency '=' 3981 nM
Q965D5 BXGT019600 Enoyl-acyl-carrier protein reductase unreviewed - fabI Ki '=' 8 nM
P0AEK4 BXGT007320 Enoyl-[acyl-carrier-protein] reductase [NADH] FabI reviewed - fabI IC50 '=' 15000 nM
Q962Y6 BXGT019597 Thioredoxin glutathione reductase unreviewed - TGR Potency '=' 11220 nM
O14746 BXGT004091 Telomerase reverse transcriptase reviewed Enzyme TERT IC50 '=' 1080 nM
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Inhibition '=' 95 %
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A reviewed - KMT2A Potency '=' 17782 nM
O00255 BXGT003903 Menin reviewed - MEN1 Potency '=' 17782 nM
P02768 BXGT005955 Serum albumin reviewed Transporter ALB Activity '=' 99 %
O14746 BXGT004091 Telomerase reverse transcriptase reviewed Enzyme TERT IC50 '=' 1180 nM
P56817 BXGT011200 Beta-secretase 1 reviewed Enzyme BACE1 Inhibition '=' 0 %
P08246 BXGT006756 Neutrophil elastase reviewed Enzyme ELANE Inhibition '=' 88 %
P08659 BXGT006805 Luciferin 4-monooxygenase reviewed - Potency - 21331 nM
P05362 BXGT006350 Intercellular adhesion molecule 1 reviewed - ICAM1 Inhibition '=' 85 %
O95342 BXGT005373 Bile salt export pump reviewed Transporter ABCB11 Activity - - -
P02768 BXGT005955 Serum albumin reviewed Transporter ALB Activity '=' 85 %
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 61130 nM
Q9XUB2 BXGT022194 Zinc finger protein mex-5 reviewed - mex-5 EC50 '=' 727 nM
O60218 BXGT004858 Aldo-keto reductase family 1 member B10 reviewed Enzyme AKR1B10 Inhibition - - -
P08865 BXGT006832 40S ribosomal protein SA reviewed Nucleic acid binding RPSA Inhibition '=' 47 %
P12276 BXGT007788 Fatty acid synthase reviewed - FASN IC50 '=' 100000 nM
Q92831 BXGT019380 Histone acetyltransferase KAT2B reviewed - KAT2B IC50 '=' 60000 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 IC50 '=' 124 nM
P80025 BXGT011867 Lactoperoxidase reviewed - LPO Km '=' 320 nM
P06786 BXGT006505 DNA topoisomerase 2 reviewed - TOP2 IC50 '=' 3000000 nM
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP IC50 '=' 4600 nM
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 reviewed Epigenetic regulator DNMT1 IC50 '=' 500 nM
O95342 BXGT005373 Bile salt export pump reviewed Transporter ABCB11 IC50 '=' 214000 nM
Q965D7 BXGT019602 Beta-hydroxyacyl-ACP dehydratase unreviewed - fabZ IC50 '=' 30 nM
P56817 BXGT011200 Beta-secretase 1 reviewed Enzyme BACE1 Inhibition '=' -11 %
P81908 BXGT011959 Cholinesterase reviewed - BCHE Inhibition '=' -4 %
P02768 BXGT005955 Serum albumin reviewed Transporter ALB Activity '=' 68 %
P56817 BXGT011200 Beta-secretase 1 reviewed Enzyme BACE1 RFU '=' 87 -
P56817 BXGT011200 Beta-secretase 1 reviewed Enzyme BACE1 RFU '=' 88 -
P04745 BXGT006255 Alpha-amylase 1 reviewed - AMY1A IC50 '=' 1400000 nM
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Activity '=' 16 %
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP IC50 '=' 3000 nM
P02768 BXGT005955 Serum albumin reviewed Transporter ALB Activity '=' 85 %
P11412 BXGT007700 Glucose-6-phosphate 1-dehydrogenase reviewed - ZWF1 IC50 '=' 250 nM
P02766 BXGT005953 Transthyretin reviewed Transporter TTR Kd '=' 400 nM
P02766 BXGT005953 Transthyretin reviewed Transporter TTR Activity - - -
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 IC50 '=' 122 nM
Q8I2S7 BXGT018209 3-oxoacyl-[acyl-carrier-protein] reductase unreviewed - PF3D7_0922900 IC50 '=' 320 nM
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Inhibition - - -
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP IC50 '=' 100000 nM
P27487 BXGT009187 Dipeptidyl peptidase 4 reviewed Enzyme DPP4 IC50 '=' 10210 nM
P18669 BXGT008419 Phosphoglycerate mutase 1 reviewed - PGAM1 IC50 '=' 490 nM
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP IC50 '=' 500 nM
P80025 BXGT011867 Lactoperoxidase reviewed - LPO Kcat '=' 13 /s
P12821 BXGT007849 Angiotensin-converting enzyme reviewed Enzyme ACE Inhibition '=' 82 %
Q92793 BXGT019374 CREB-binding protein reviewed - CREBBP IC50 '=' 50000 nM
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Inhibition '=' 86 %
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase reviewed - APEX1 Potency - 891 nM
V9HWB9 BXGT026149 L-lactate dehydrogenase unreviewed - HEL-S-133P Inhibition '=' 63 %
O14684 BXGT004082 Prostaglandin E synthase reviewed - PTGES IC50 '=' 1800 nM
P21554 BXGT008662 Cannabinoid receptor 1 reviewed G-protein coupled receptor CNR1 Ki '=' 33600 nM
Q09472 BXGT013038 Histone acetyltransferase p300 reviewed - EP300 IC50 '=' 30000 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00038 Tea Camellia sinensis Teas
BXGF00183 Common thyme Thymus vulgaris Herbs and Spices
BXGF00337 Ginkgo nuts Ginkgo biloba Herbs and Spices
BXGF00432 Sesbania flower Sesbania bispinosa Vegetables
BXGF00729 Shea tree Vitellaria paradoxa Herbs and Spices
BXGF00787 Yellow pond-lily Nuphar lutea Herbs and Spices
BXGF00804 Chinese bayberry Myrica rubra Fruits
BXGF00852 Triaenophora rupestris Triaenophora rupestris Others
BXGF00878 Lespedeza bicolor Lespedeza bicolor Medicinal Plant
BXGF00924 Phoenix loureiroi Phoenix loureiroi Medicinal Plant
BXGF00926 Larix cajanderi Larix cajanderi Others
BXGF00968 Thalictrum longistylum Thalictrum longistylum Medicinal Plant
BXGF01010 Sextonia rubra Sextonia rubra Others
BXGF01045 Dioscorea japonica Dioscorea japonica Medicinal Plant
BXGF01181 Atylosia trinervia Atylosia trinervia Others
BXGF01208 Angelica lucida Angelica lucida Human Edible Plant
BXGF01219 Salvia parryi Salvia parryi Others
BXGF01229 Strophanthus kombe Strophanthus kombe Medicinal Plant
BXGF01264 Cedrus libani Cedrus libani Medicinal Plant
BXGF01271 Castanea vesca Castanea vesca Others
BXGF01272 Iris ensata Iris ensata Medicinal Plant
BXGF01297 Justicia paniculata Justicia paniculata Medicinal Plant
BXGF01340 Khaya ivorensis Khaya ivorensis Medicinal Plant
BXGF01425 Craspidospermum verticillatum Craspidospermum verticillatum Others
BXGF01472 Cerinthe minor Cerinthe minor Others
BXGF01502 Ixeris stolonifera Ixeris stolonifera Medicinal Plant
BXGF01516 Petasites georgicus Petasites georgicus Others
BXGF01535 Cephalaria grossheimii Cephalaria grossheimii Others
BXGF01597 Senegalia catechu Senegalia catechu Medicinal Plant
BXGF01626 Nerine bowdenii Nerine bowdenii Others
BXGF01630 Cotula cinerea Cotula cinerea Medicinal Plant
BXGF01638 Lotus japonicus Lotus japonicus Others
BXGF01679 Melaleuca rhaphiophylla Melaleuca rhaphiophylla Others
BXGF01706 Daphniphyllum paxianum Daphniphyllum paxianum Others
BXGF01726 Senecio renardii Senecio renardii Medicinal Plant
BXGF01760 Hypericum ascyron Hypericum ascyron Medicinal Plant
BXGF01789 Aristolochia zollingeriana Aristolochia zollingeriana Others
BXGF01827 Melochia tomentosa Melochia tomentosa Others
BXGF02268 Ginkgo semen Ginkgo semen Others
BXGF02294 Bartramia pomiformis Bartramia pomiformis Medicinal Plant
BXGF02400 Hylotelephium telephium Hylotelephium telephium Medicinal Plant
BXGF02763 Iryanthera coriacea Iryanthera coriacea Others
BXGF02773 Carica pennata Carica pennata Others
BXGF02989 Turpinia ternata Turpinia ternata Medicinal Plant
BXGF03109 Cneoridium dumosum Cneoridium dumosum Others
BXGF03131 Astragalus cibarius Astragalus cibarius Medicinal Plant
BXGF03205 Veratrum dahuricum Veratrum dahuricum Others
BXGF03219 Hymenoxys insignis Hymenoxys insignis Others
BXGF03230 Ehretia dicksonii Ehretia dicksonii Medicinal Plant
BXGF03291 Vernonia menthaefolia Vernonia menthaefolia Others
BXGF03353 Aconitum heterophylloides Aconitum heterophylloides Others
BXGF03361 Alyxia reinwardtii Alyxia reinwardtii Medicinal Plant
BXGF03398 Solanum nigrum Solanum nigrum Medicinal Plant
BXGF03426 Rhodiola crenulata Rhodiola crenulata Medicinal Plant
BXGF03461 Microtropis fokienensis Microtropis fokienensis Others
BXGF03658 Centaurea linifolia Centaurea linifolia Others
BXGF03726 Serratula inermis Serratula inermis Others
BXGF03804 Machilus macrantha Machilus macrantha Medicinal Plant
BXGF04079 Senna siamea Senna siamea Medicinal Plant
BXGF04094 Virola multinervia Virola multinervia Medicinal Plant
BXGF04200 Euphorbia hirta Euphorbia hirta Medicinal Plant
BXGF04481 Rubia oncotricha Rubia oncotricha Medicinal Plant
BXGF04556 Xyris pterygoblephara Xyris pterygoblephara Others
BXGF04576 Boronia coerulescens Boronia coerulescens Others
BXGF04589 Ilex purpurea Ilex purpurea Others
BXGF04607 Morus alba Morus alba Medicinal Plant
BXGF04637 Acanthophyllum elatius Acanthophyllum elatius Others
BXGF04987 Honorius nutans Honorius nutans Others
BXGF05015 Balanophora involucrata Balanophora involucrata Medicinal Plant
BXGF05094 Lupinus verbasciformis Lupinus verbasciformis Others
BXGF05195 Limonium sinense Limonium sinense Others
BXGF05244 Elephantopus mollis Elephantopus mollis Medicinal Plant
BXGF05295 Gomortega keule Gomortega keule Human Edible Plant
BXGF05389 Limonium gmelinii Limonium gmelinii Medicinal Plant
BXGF05517 Quercus robur Quercus robur Medicinal Plant
BXGF05522 Solidago serotina Solidago serotina Others
BXGF05600 Aframomum amaniense Aframomum amaniense Others
BXGF05689 Artemisia klotzchiana Artemisia klotzchiana Others
BXGF05714 Khaya senegalensis Khaya senegalensis Medicinal Plant
BXGF05732 Mimusops caffra Mimusops caffra Human Edible Plant
BXGF05776 Picea mariana Picea mariana Medicinal Plant
BXGF05795 Nama hispidum Nama hispidum Others
BXGF05828 Viguiera oblongifolia Viguiera oblongifolia Others
BXGF05900 Beilschmiedia anacardioides Beilschmiedia anacardioides Medicinal Plant
BXGF05967 Veronica arvensis Veronica arvensis Medicinal Plant
BXGF06034 Viburnum urceolatum Viburnum urceolatum Others
BXGF06088 Euryops algoensis Euryops algoensis Others
BXGF06096 Artemisia schimperi Artemisia schimperi Others
BXGF06167 Sorbaria sorbifolia Sorbaria sorbifolia Medicinal Plant
BXGF06183 Adina sessilifolia Adina sessilifolia Others
BXGF06238 Gardenia jasminoides Gardenia jasminoides Medicinal Plant
BXGF06263 Litsea pungens Litsea pungens Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease