Showing entry for Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008682
Protein NameGlycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
Uniport IdP21695
GeneGPD1
Gene Id2819
DomainNAD_Gly3P_dh_C; NAD_Gly3P_dh_N
Pfam PF07479   PF01210  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.3 Lipid metabolism hsa00564 Glycerophospholipid metabolism
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071320 cellular response to cAMP
Biological Process GO:0071356 cellular response to tumor necrosis factor
Biological Process GO:0006094 gluconeogenesis
Biological Process GO:0046168 glycerol-3-phosphate catabolic process
Biological Process GO:0006072 glycerol-3-phosphate metabolic process
Biological Process GO:0006127 glycerophosphate shuttle
Biological Process GO:0006116 NADH oxidation
Biological Process GO:0006654 phosphatidic acid biosynthetic process
Biological Process GO:0045821 positive regulation of glycolytic process
molecular function GO:0004368 glycerol-3-phosphate dehydrogenase (quinone) activity
molecular function GO:0051287 NAD binding
molecular function GO:0042803 protein homodimerization activity
cellular component GO:0005829 cytosol
cellular component GO:0070062 extracellular exosome
cellular component GO:0009331 glycerol-3-phosphate dehydrogenase complex
molecular function GO:0004367 glycerol-3-phosphate dehydrogenase NAD+ activity
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-1483166 Synthesis of PA
R-HSA-1483206 Glycerophospholipid biosynthesis
R-HSA-1483257 Phospholipid metabolism
R-HSA-556833 Metabolism of lipids
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000772 BXGD000009 Multiple congenital anomalies Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0013336 BXGD000815 Dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0019193 BXGD001299 Hepatitis, Toxic Digestive System Diseases; Chemically-Induced Disorders
C0019209 BXGD001305 Hepatomegaly Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0020443 BXGD001385 Hypercholesterolemia Nutritional and Metabolic Diseases
C0020557 BXGD001432 Hypertriglyceridemia Nutritional and Metabolic Diseases
C0025521 BXGD001876 Inborn Errors of Metabolism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0043459 BXGD003048 Zellweger Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Nutritional and Metabolic Diseases; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Nervous System Diseases
C0239946 BXGD005010 Fibrosis, Liver Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0282527 BXGD006811 Infantile Refsum Disease (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0342276 BXGD007449 Maturity onset diabetes mellitus in young Nutritional and Metabolic Diseases; Endocrine System Diseases
C0349588 BXGD007933 Short stature
C0432072 BXGD008718 Dysmorphic features
C0520679 BXGD009101 Sleep Apnea, Obstructive Respiratory Tract Diseases; Nervous System Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0860207 BXGD011220 Drug-Induced Liver Disease Digestive System Diseases; Chemically-Induced Disorders
C1262760 BXGD011886 Hepatitis, Drug-Induced Digestive System Diseases; Chemically-Induced Disorders
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1848701 BXGD014967 Elevated hepatic transaminase
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C2919142 BXGD017867 Short Stature, CTCAE
C3266262 BXGD018600 Multiple Chronic Conditions Pathological Conditions, Signs and Symptoms
C3280953 BXGD018871 HYPERTRIGLYCERIDEMIA, TRANSIENT INFANTILE
C3658290 BXGD019256 Drug-Induced Acute Liver Injury Digestive System Diseases; Chemically-Induced Disorders
C4277682 BXGD022376 Chemical and Drug Induced Liver Injury Digestive System Diseases; Chemically-Induced Disorders
C4279912 BXGD022378 Chemically-Induced Liver Toxicity Digestive System Diseases; Chemically-Induced Disorders
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0001096 Dihydroxyacetone phosphate 170.06
BXGC0002586 Calcium 40.08
BXGC0002591 Potassium 39.1
BXGC0030663 Metformin 129.1
BXGC0037687 (4S)-2-methylpentane-2,4-diol 118.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein