Showing entry for Multiple Chronic Conditions


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD018600
Disease NameMultiple Chronic Conditions
Disease CUI IdC3266262
MeSH Codes C23  
Disease Class NamePathological Conditions, Signs and Symptoms
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
F7VJQ1 BXGT003310 Alternative prion protein 5621 reviewed
O00142 BXGT003883 Thymidine kinase 2, mitochondrial 7084 reviewed Kinase
O00241 BXGT003901 Signal-regulatory protein beta-1 10326 reviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O00337 BXGT003911 Sodium/nucleoside cotransporter 1 9154 reviewed Transporter
O00512 BXGT003933 B-cell CLL/lymphoma 9 protein 607 reviewed
O00767 BXGT003949 Acyl-CoA desaturase 6319 reviewed
O14733 BXGT004087 Dual specificity mitogen-activated protein kinase kinase 7 5609 reviewed Kinase
O14745 BXGT004090 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 9368 reviewed
O14746 BXGT004091 Telomerase reverse transcriptase 7015 reviewed Enzyme
O14757 BXGT004092 Serine/threonine-protein kinase Chk1 1111 reviewed Kinase
O14931 BXGT004113 Natural cytotoxicity triggering receptor 3 259197 reviewed
O15151 BXGT004132 Protein Mdm4 4194 reviewed Nucleic acid binding
O15164 BXGT004133 Transcription intermediary factor 1-alpha 8805 reviewed
O15244 BXGT004140 Solute carrier family 22 member 2 6582 reviewed Transporter
O15245 BXGT004141 Solute carrier family 22 member 1 6580 reviewed Transporter
O15438 BXGT004168 Canalicular multispecific organic anion transporter 2 8714 reviewed Transporter
O15439 BXGT004169 Multidrug resistance-associated protein 4 10257 reviewed Transporter
O15455 BXGT004171 Toll-like receptor 3 7098 reviewed Receptor
O43324 BXGT004588 Eukaryotic translation elongation factor 1 epsilon-1 9521 reviewed
O43451 BXGT004594 Maltase-glucoamylase, intestinal 8972 reviewed Enzyme
O43521 BXGT004598 Bcl-2-like protein 11 10018 reviewed
O43914 BXGT004635 TYRO protein tyrosine kinase-binding protein 7305 reviewed
O60260 BXGT004864 E3 ubiquitin-protein ligase parkin 5071 reviewed Enzyme
O60494 BXGT004879 Cubilin 8029 reviewed
O60563 BXGT004883 Cyclin-T1 904 reviewed Enzyme modulator
O60603 BXGT004887 Toll-like receptor 2 7097 reviewed
O60674 BXGT004892 Tyrosine-protein kinase JAK2 3717 reviewed Kinase
O60760 BXGT004899 Hematopoietic prostaglandin D synthase 27306 reviewed
O60885 BXGT004906 Bromodomain-containing protein 4 23476 reviewed Epigenetic regulator
O60931 BXGT004911 Cystinosin 1497 reviewed
O75030 BXGT005096 Microphthalmia-associated transcription factor 4286 reviewed
O75116 BXGT005100 Rho-associated protein kinase 2 9475 reviewed Kinase
O75311 BXGT005109 Glycine receptor subunit alpha-3 8001 reviewed Ion channel
O75469 BXGT005128 Nuclear receptor subfamily 1 group I member 2 8856 reviewed Nuclear receptor
O75923 BXGT005166 Dysferlin 8291 reviewed Transporter
O94811 BXGT005336 Tubulin polymerization-promoting protein 11076 reviewed Cellular structure
O95069 BXGT005348 Potassium channel subfamily K member 2 3776 reviewed Ion channel
O95255 BXGT005363 Multidrug resistance-associated protein 6 368 reviewed Transporter
O95257 BXGT005365 Growth arrest and DNA damage-inducible protein GADD45 gamma 10912 reviewed
O95477 BXGT005383 Phospholipid-transporting ATPase ABCA1 19 reviewed Transporter
O95551 BXGT005384 Tyrosyl-DNA phosphodiesterase 2 51567 reviewed
O96017 BXGT005415 Serine/threonine-protein kinase Chk2 11200 reviewed Kinase
P00338 BXGT005504 L-lactate dehydrogenase A chain 3939 reviewed Enzyme
P00374 BXGT005520 Dihydrofolate reductase 1719 reviewed Enzyme
P00390 BXGT005526 Glutathione reductase, mitochondrial 2936 reviewed Enzyme
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P00450 BXGT005544 Ceruloplasmin 1356 reviewed Enzyme
P00492 BXGT005556 Hypoxanthine-guanine phosphoribosyltransferase 3251 reviewed Enzyme
P00519 BXGT005570 Tyrosine-protein kinase ABL1 25 reviewed Kinase
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00746 BXGT005638 Complement factor D 1675 reviewed Enzyme
P00750 BXGT005642 Tissue-type plasminogen activator 5327 reviewed Enzyme
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P01009 BXGT005714 Alpha-1-antitrypsin 5265 reviewed Enzyme modulator
P01011 BXGT005715 Alpha-1-antichymotrypsin 12 reviewed Enzyme modulator
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01023 BXGT005718 Alpha-2-macroglobulin 2 reviewed Enzyme modulator
P01106 BXGT005730 Myc proto-oncogene protein 4609 reviewed Transcription factor
P01111 BXGT005731 GTPase NRas 4893 reviewed Enzyme modulator
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01130 BXGT005735 Low-density lipoprotein receptor 3949 reviewed
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01275 BXGT005747 Glucagon 2641 reviewed
P01308 BXGT005749 Insulin 3630 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01732 BXGT005782 T-cell surface glycoprotein CD8 alpha chain 925 reviewed
P01889 BXGT005809 HLA class I histocompatibility antigen, B-7 alpha chain 3106 reviewed
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P02533 BXGT005887 Keratin, type I cytoskeletal 14 3861 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02655 BXGT005912 Apolipoprotein C-II 344 reviewed
P02656 BXGT005913 Apolipoprotein C-III 345 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P02818 BXGT005969 Osteocalcin 632 reviewed
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P04004 BXGT006125 Vitronectin 7448 reviewed
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04049 BXGT006133 RAF proto-oncogene serine/threonine-protein kinase 5894 reviewed Kinase
P04156 BXGT006156 Major prion protein 5621 reviewed
P04271 BXGT006177 Protein S100-B 6285 reviewed Calcium-binding protein
P04275 BXGT006180 von Willebrand factor 7450 reviewed Enzyme modulator
P04278 BXGT006182 Sex hormone-binding globulin 6462 reviewed
P04406 BXGT006207 Glyceraldehyde-3-phosphate dehydrogenase 2597 reviewed Enzyme
P04424 BXGT006214 Argininosuccinate lyase 435 reviewed Enzyme
P04440 BXGT006216 HLA class II histocompatibility antigen, DP beta 1 chain 3115 reviewed Immune response
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04745 BXGT006255 Alpha-amylase 1 278 reviewed
P04798 BXGT006265 Cytochrome P450 1A1 1543 reviewed Enzyme
P04818 BXGT006269 Thymidylate synthase 7298 reviewed Enzyme
P04839 BXGT006273 Cytochrome b-245 heavy chain 1536 reviewed Ion channel
P05067 BXGT006306 Amyloid-beta precursor protein 351 reviewed Enzyme modulator
P05107 BXGT006316 Integrin beta-2 3689 reviewed Receptor
P05109 BXGT006318 Protein S100-A8 6279 reviewed Calcium-binding protein
P05155 BXGT006328 Plasma protease C1 inhibitor 710 reviewed Enzyme modulator
P05164 BXGT006333 Myeloperoxidase 4353 reviewed Enzyme
P05187 BXGT006339 Alkaline phosphatase, placental type 250 reviewed Enzyme
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P06241 BXGT006429 Tyrosine-protein kinase Fyn 2534 reviewed Kinase
P06276 BXGT006430 Cholinesterase 590 reviewed
P06493 BXGT006445 Cyclin-dependent kinase 1 983 reviewed Kinase
P06702 BXGT006476 Protein S100-A9 6280 reviewed Calcium-binding protein
P06731 BXGT006488 Carcinoembryonic antigen-related cell adhesion molecule 5 1048 reviewed
P06744 BXGT006494 Glucose-6-phosphate isomerase 2821 reviewed Enzyme
P06850 BXGT006511 Corticoliberin 1392 reviewed Signaling
P07101 BXGT006547 Tyrosine 3-monooxygenase 7054 reviewed
P07225 BXGT006572 Vitamin K-dependent protein S 5627 reviewed
P07288 BXGT006591 Prostate-specific antigen 354 reviewed Enzyme
P07355 BXGT006609 Annexin A2 302 reviewed
P07858 BXGT006689 Cathepsin B 1508 reviewed Enzyme
P07949 BXGT006703 Proto-oncogene tyrosine-protein kinase receptor Ret 5979 reviewed Kinase
P07996 BXGT006710 Thrombospondin-1 7057 reviewed
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08575 BXGT006793 Receptor-type tyrosine-protein phosphatase C 5788 reviewed Enzyme
P08581 BXGT006794 Hepatocyte growth factor receptor 4233 reviewed Kinase
P08684 BXGT006812 Cytochrome P450 3A4 1576 reviewed Enzyme
P08700 BXGT006816 Interleukin-3 3562 reviewed
P08922 BXGT006843 Proto-oncogene tyrosine-protein kinase ROS 6098 reviewed Kinase
P09038 BXGT006851 Fibroblast growth factor 2 2247 reviewed Signaling
P09104 BXGT006856 Gamma-enolase 2026 reviewed Enzyme
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P09237 BXGT006874 Matrilysin 4316 reviewed Enzyme
P09382 BXGT006882 Galectin-1 3956 reviewed Signaling
P09429 BXGT006889 High mobility group protein B1 3146 reviewed Nucleic acid binding
P09466 BXGT006892 Glycodelin 5047 reviewed Enzyme
P09486 BXGT006897 SPARC 6678 reviewed Signaling
P09488 BXGT006899 Glutathione S-transferase Mu 1 2944 reviewed
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P09874 BXGT006934 Poly [ADP-ribose] polymerase 1 142 reviewed
P09917 BXGT006941 Arachidonate 5-lipoxygenase 240 reviewed Enzyme
P09923 BXGT006942 Intestinal-type alkaline phosphatase 248 reviewed Enzyme
P09958 BXGT006950 Furin 5045 reviewed Enzyme
P10070 BXGT007534 Zinc finger protein GLI2 2736 reviewed
P10144 BXGT007541 Granzyme B 3002 reviewed Enzyme
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10323 BXGT007557 Acrosin 49 reviewed Enzyme
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10635 BXGT007595 Cytochrome P450 2D6 1565 reviewed
P10646 BXGT007598 Tissue factor pathway inhibitor 7035 reviewed Enzyme modulator
P10747 BXGT007609 T-cell-specific surface glycoprotein CD28 940 reviewed
P10809 BXGT007617 60 kDa heat shock protein, mitochondrial 3329 reviewed
P10909 BXGT007630 Clusterin 1191 reviewed
P10997 BXGT007643 Islet amyloid polypeptide 3375 reviewed Signaling
P11021 BXGT007644 Endoplasmic reticulum chaperone BiP 3309 reviewed
P11142 BXGT007658 Heat shock cognate 71 kDa protein 3312 reviewed
P11168 BXGT007663 Solute carrier family 2, facilitated glucose transporter member 2 6514 reviewed Transporter
P11215 BXGT007672 Integrin alpha-M 3684 reviewed
P11226 BXGT007675 Mannose-binding protein C 4153 reviewed Receptor
P11274 BXGT007681 Breakpoint cluster region protein 613 reviewed Enzyme modulator
P11309 BXGT007685 Serine/threonine-protein kinase pim-1 5292 reviewed Kinase
P11387 BXGT007696 DNA topoisomerase 1 7150 reviewed Enzyme
P11388 BXGT007697 DNA topoisomerase 2-alpha 7153 reviewed
P11413 BXGT007701 Glucose-6-phosphate 1-dehydrogenase 2539 reviewed Enzyme
P11597 BXGT007727 Cholesteryl ester transfer protein 1071 reviewed
P12643 BXGT007830 Bone morphogenetic protein 2 650 reviewed Signaling
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P12830 BXGT007852 Cadherin-1 999 reviewed
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13501 BXGT007917 C-C motif chemokine 5 6352 reviewed Signaling
P13569 BXGT007923 Cystic fibrosis transmembrane conductance regulator 1080 reviewed Ion channel
P13688 BXGT007943 Carcinoembryonic antigen-related cell adhesion molecule 1 634 reviewed
P13726 BXGT007950 Tissue factor 2152 reviewed Receptor
P14151 BXGT007990 L-selectin 6402 reviewed
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14410 BXGT008009 Sucrase-isomaltase, intestinal 6476 reviewed Enzyme
P14550 BXGT008019 Aldo-keto reductase family 1 member A1 10327 reviewed Enzyme
P14679 BXGT008039 Tyrosinase 7299 reviewed Enzyme
P14866 BXGT008060 Heterogeneous nuclear ribonucleoprotein L 3191 reviewed
P14868 BXGT008062 Aspartate--tRNA ligase, cytoplasmic 1615 reviewed Enzyme
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P15529 BXGT008134 Membrane cofactor protein 4179 reviewed
P15531 BXGT008136 Nucleoside diphosphate kinase A 4830 reviewed Kinase
P15559 BXGT008139 NAD(P)H dehydrogenase [quinone] 1 1728 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P15924 BXGT008171 Desmoplakin 1832 reviewed Cellular structure
P16070 BXGT008186 CD44 antigen 960 reviewed
P16442 BXGT008227 Histo-blood group ABO system transferase 28 reviewed Enzyme
P16455 BXGT008229 Methylated-DNA--protein-cysteine methyltransferase 4255 reviewed
P16671 BXGT008255 Platelet glycoprotein 4 948 reviewed Receptor
P16930 BXGT008272 Fumarylacetoacetase 2184 reviewed
P17252 BXGT008294 Protein kinase C alpha type 5578 reviewed Kinase
P17735 BXGT008335 Tyrosine aminotransferase 6898 reviewed
P17931 BXGT008356 Galectin-3 3958 reviewed Signaling
P17936 BXGT008357 Insulin-like growth factor-binding protein 3 3486 reviewed Enzyme modulator
P18074 BXGT008374 General transcription and DNA repair factor IIH helicase subunit XPD 2068 reviewed Enzyme
P18089 BXGT008379 Alpha-2B adrenergic receptor 151 reviewed G-protein coupled receptor
P19429 BXGT008479 Troponin I, cardiac muscle 7137 reviewed Cellular structure
P19623 BXGT008503 Spermidine synthase 6723 reviewed Enzyme
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit 4790 reviewed Transcription factor
P19883 BXGT008528 Follistatin 10468 reviewed Enzyme modulator
P20132 BXGT008546 L-serine dehydratase/L-threonine deaminase 10993 reviewed Enzyme
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 1131 reviewed G-protein coupled receptor
P20711 BXGT008594 Aromatic-L-amino-acid decarboxylase 1644 reviewed
P20813 BXGT008603 Cytochrome P450 2B6 1555 reviewed
P21333 BXGT008638 Filamin-A 2316 reviewed
P21359 BXGT008640 Neurofibromin 4763 reviewed Enzyme modulator
P21579 BXGT008665 Synaptotagmin-1 6857 reviewed Transporter
P21583 BXGT008667 Kit ligand 4254 reviewed
P21695 BXGT008682 Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic 2819 reviewed Enzyme
P21709 BXGT008685 Ephrin type-A receptor 1 2041 reviewed Kinase
P21796 BXGT008690 Voltage-dependent anion-selective channel protein 1 7416 reviewed
P21917 BXGT008707 D(4) dopamine receptor 1815 reviewed G-protein coupled receptor
P21918 BXGT008708 D(1B) dopamine receptor 1816 reviewed G-protein coupled receptor
P21964 BXGT008714 Catechol O-methyltransferase 1312 reviewed Enzyme
P21980 BXGT008715 Protein-glutamine gamma-glutamyltransferase 2 7052 reviewed Enzyme
P22033 BXGT008721 Methylmalonyl-CoA mutase, mitochondrial 4594 reviewed Enzyme
P22303 BXGT008751 Acetylcholinesterase 43 reviewed Enzyme
P22681 BXGT008795 E3 ubiquitin-protein ligase CBL 867 reviewed Enzyme
P22891 BXGT008813 Vitamin K-dependent protein Z 8858 reviewed Enzyme
P23141 BXGT008830 Liver carboxylesterase 1 1066 reviewed Enzyme
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P24158 BXGT008951 Myeloblastin 5657 reviewed Enzyme
P24298 BXGT008960 Alanine aminotransferase 1 2875 reviewed Enzyme
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P24855 BXGT008998 Deoxyribonuclease-1 1773 reviewed
P25021 BXGT009004 Histamine H2 receptor 3274 reviewed G-protein coupled receptor
P25101 BXGT009018 Endothelin-1 receptor 1909 reviewed G-protein coupled receptor
P25440 BXGT009044 Bromodomain-containing protein 2 6046 reviewed Epigenetic regulator
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 1786 reviewed Epigenetic regulator
P27338 BXGT009172 Amine oxidase [flavin-containing] B 4129 reviewed
P27361 BXGT009176 Mitogen-activated protein kinase 3 5595 reviewed Kinase
P27487 BXGT009187 Dipeptidyl peptidase 4 1803 reviewed Enzyme
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase 328 reviewed
P27797 BXGT009206 Calreticulin 811 reviewed Calcium-binding protein
P29033 BXGT009308 Gap junction beta-2 protein 2706 reviewed Cell-cell junction
P29350 BXGT009335 Tyrosine-protein phosphatase non-receptor type 6 5777 reviewed
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P30086 BXGT009400 Phosphatidylethanolamine-binding protein 1 5037 reviewed Enzyme modulator
P30101 BXGT009402 Protein disulfide-isomerase A3 2923 reviewed
P30279 BXGT009415 G1/S-specific cyclin-D2 894 reviewed Enzyme modulator
P30536 BXGT009435 Translocator protein 706 reviewed
P30711 BXGT009460 Glutathione S-transferase theta-1 2952 reviewed
P30838 BXGT009471 Aldehyde dehydrogenase, dimeric NADP-preferring 218 reviewed
P30876 BXGT009476 DNA-directed RNA polymerase II subunit RPB2 5431 reviewed Enzyme
P30988 BXGT009491 Calcitonin receptor 799 reviewed G-protein coupled receptor
P31391 BXGT009535 Somatostatin receptor type 4 6754 reviewed G-protein coupled receptor
P31645 BXGT009558 Sodium-dependent serotonin transporter 6532 reviewed Transporter
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P31751 BXGT009576 RAC-beta serine/threonine-protein kinase 208 reviewed Kinase
P32418 BXGT009635 Sodium/calcium exchanger 1 6546 reviewed Transporter
P33032 BXGT009689 Melanocortin receptor 5 4161 reviewed G-protein coupled receptor
P33121 BXGT009692 Long-chain-fatty-acid--CoA ligase 1 2180 reviewed Enzyme
P33527 BXGT009728 Multidrug resistance-associated protein 1 4363 reviewed Transporter
P33681 BXGT009739 T-lymphocyte activation antigen CD80 941 reviewed
P34932 BXGT009772 Heat shock 70 kDa protein 4 3308 reviewed
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P35348 BXGT009814 Alpha-1A adrenergic receptor 148 reviewed G-protein coupled receptor
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35372 BXGT009823 Mu-type opioid receptor 4988 reviewed G-protein coupled receptor
P35475 BXGT009837 Alpha-L-iduronidase 3425 reviewed Enzyme
P35610 BXGT009855 Sterol O-acyltransferase 1 6646 reviewed Enzyme
P35613 BXGT009856 Basigin 682 reviewed
P35916 BXGT009881 Vascular endothelial growth factor receptor 3 2324 reviewed Kinase
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P36888 BXGT009938 Receptor-type tyrosine-protein kinase FLT3 2322 reviewed Kinase
P37840 BXGT010015 Alpha-synuclein 6622 reviewed Transporter
P38398 BXGT010037 Breast cancer type 1 susceptibility protein 672 reviewed Enzyme
P38936 BXGT010074 Cyclin-dependent kinase inhibitor 1 1026 reviewed
P39019 BXGT010082 40S ribosomal protein S19 6223 reviewed Nucleic acid binding
P40225 BXGT010168 Thrombopoietin 7066 reviewed
P40337 BXGT010174 von Hippel-Lindau disease tumor suppressor 7428 reviewed Enzyme
P40692 BXGT010195 DNA mismatch repair protein Mlh1 4292 reviewed Nucleic acid binding
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P40967 BXGT010212 Melanocyte protein PMEL 6490 reviewed Signaling
P41143 BXGT010223 Delta-type opioid receptor 4985 reviewed G-protein coupled receptor
P41146 BXGT010226 Nociceptin receptor 4987 reviewed G-protein coupled receptor
P41180 BXGT010230 Extracellular calcium-sensing receptor 846 reviewed G-protein coupled receptor
P41594 BXGT010266 Metabotropic glutamate receptor 5 2915 reviewed G-protein coupled receptor
P41597 BXGT010268 C-C chemokine receptor type 2 729230 reviewed
P42263 BXGT010295 Glutamate receptor 3 2892 reviewed Ion channel
P42330 BXGT010301 Aldo-keto reductase family 1 member C3 8644 reviewed Enzyme
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P43003 BXGT010347 Excitatory amino acid transporter 1 6507 reviewed Transporter
P43220 BXGT010367 Glucagon-like peptide 1 receptor 2740 reviewed G-protein coupled receptor
P46098 BXGT010507 5-hydroxytryptamine receptor 3A 3359 reviewed Ion channel
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P47712 BXGT010577 Cytosolic phospholipase A2 5321 reviewed Enzyme
P47871 BXGT010592 Glucagon receptor 2642 reviewed G-protein coupled receptor
P47989 BXGT010602 Xanthine dehydrogenase/oxidase 7498 reviewed Enzyme
P48029 BXGT010606 Sodium- and chloride-dependent creatine transporter 1 6535 reviewed Transporter
P48735 BXGT010657 Isocitrate dehydrogenase [NADP], mitochondrial 3418 reviewed
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49281 BXGT010689 Natural resistance-associated macrophage protein 2 4891 reviewed Transporter
P49589 BXGT010714 Cysteine--tRNA ligase, cytoplasmic 833 reviewed Enzyme
P49591 BXGT010715 Serine--tRNA ligase, cytoplasmic 6301 reviewed Enzyme
P49711 BXGT010728 Transcriptional repressor CTCF 10664 reviewed Transcription factor
P49768 BXGT010740 Presenilin-1 5663 reviewed Enzyme
P49789 BXGT010742 Bis(5'-adenosyl)-triphosphatase 2272 reviewed
P49792 BXGT010743 E3 SUMO-protein ligase RanBP2 5903 reviewed Enzyme modulator
P50750 BXGT010818 Cyclin-dependent kinase 9 1025 reviewed Kinase
P51843 BXGT010897 Nuclear receptor subfamily 0 group B member 1 190 reviewed Nuclear receptor
P52788 BXGT010953 Spermine synthase 6611 reviewed
P52789 BXGT010954 Hexokinase-2 3099 reviewed Kinase
P53350 BXGT010984 Serine/threonine-protein kinase PLK1 5347 reviewed Kinase
P53396 BXGT010988 ATP-citrate synthase 47 reviewed Enzyme
P53634 BXGT011007 Dipeptidyl peptidase 1 1075 reviewed Enzyme
P54132 BXGT011032 Bloom syndrome protein 641 reviewed
P54136 BXGT011033 Arginine--tRNA ligase, cytoplasmic 5917 reviewed
P54278 BXGT011038 Mismatch repair endonuclease PMS2 5395 reviewed Nucleic acid binding
P54855 BXGT011088 UDP-glucuronosyltransferase 2B15 7366 reviewed
P55211 BXGT011111 Caspase-9 842 reviewed Enzyme
P55786 BXGT011125 Puromycin-sensitive aminopeptidase 9520 reviewed Enzyme
P55957 BXGT011137 BH3-interacting domain death agonist 637 reviewed
P56545 BXGT011178 C-terminal-binding protein 2 1488 reviewed Transcription factor
P56817 BXGT011200 Beta-secretase 1 23621 reviewed Enzyme
P56945 BXGT011206 Breast cancer anti-estrogen resistance protein 1 9564 reviewed
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P60568 BXGT011315 Interleukin-2 3558 reviewed
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P61626 BXGT011382 Lysozyme C 4069 reviewed
P62258 BXGT011415 14-3-3 protein epsilon 7531 reviewed Chaperone
P62826 BXGT011463 GTP-binding nuclear protein Ran 5901 reviewed Enzyme modulator
P63165 BXGT011506 Small ubiquitin-related modifier 1 7341 reviewed
P63244 BXGT011510 Receptor of activated protein C kinase 1 10399 reviewed
P63261 BXGT011512 Actin, cytoplasmic 2 71 reviewed Cellular structure
P78358 BXGT011838 Cancer/testis antigen 1 246100 reviewed
P80188 BXGT011882 Neutrophil gelatinase-associated lipocalin 3934 reviewed Enzyme
P80511 BXGT011914 Protein S100-A12 6283 reviewed Calcium-binding protein
P81605 BXGT011954 Dermcidin 117159 reviewed
P98164 BXGT012230 Low-density lipoprotein receptor-related protein 2 4036 reviewed
P98170 BXGT012231 E3 ubiquitin-protein ligase XIAP 331 reviewed Enzyme modulator
Q00613 BXGT012540 Heat shock factor protein 1 3297 reviewed Transcription factor
Q00796 BXGT012549 Sorbitol dehydrogenase 6652 reviewed Enzyme
Q01105 BXGT012569 Protein SET 6418 reviewed Enzyme modulator
Q01196 BXGT012575 Runt-related transcription factor 1 861 reviewed Transcription factor
Q01453 BXGT012588 Peripheral myelin protein 22 5376 reviewed Cellular structure
Q01968 BXGT012626 Inositol polyphosphate 5-phosphatase OCRL-1 4952 reviewed Enzyme
Q02750 BXGT012662 Dual specificity mitogen-activated protein kinase kinase 1 5604 reviewed Kinase
Q03518 BXGT012723 Antigen peptide transporter 1 6890 reviewed Transporter
Q04206 BXGT012754 Transcription factor p65 5970 reviewed Transcription factor
Q04756 BXGT012780 Hepatocyte growth factor activator 3083 reviewed Enzyme
Q04912 BXGT012790 Macrophage-stimulating protein receptor 4486 reviewed Kinase
Q06187 BXGT012860 Tyrosine-protein kinase BTK 695 reviewed Kinase
Q06609 BXGT012884 DNA repair protein RAD51 homolog 1 5888 reviewed
Q07021 BXGT012915 Complement component 1 Q subcomponent-binding protein, mitochondrial 708 reviewed
Q07075 BXGT012917 Glutamyl aminopeptidase 2028 reviewed Enzyme
Q07108 BXGT012919 Early activation antigen CD69 969 reviewed
Q07343 BXGT012926 cAMP-specific 3',5'-cyclic phosphodiesterase 4B 5142 reviewed
Q07812 BXGT012940 Apoptosis regulator BAX 581 reviewed Signaling
Q07820 BXGT012942 Induced myeloid leukemia cell differentiation protein Mcl-1 4170 reviewed Signaling
Q07954 BXGT012950 Prolow-density lipoprotein receptor-related protein 1 4035 reviewed
Q07955 BXGT012951 Serine/arginine-rich splicing factor 1 6426 reviewed Nucleic acid binding
Q08050 BXGT012958 Forkhead box protein M1 2305 reviewed
Q08257 BXGT012975 Quinone oxidoreductase 1429 reviewed
Q08722 BXGT013002 Leukocyte surface antigen CD47 961 reviewed
Q12778 BXGT013263 Forkhead box protein O1 2308 reviewed
Q12931 BXGT013282 Heat shock protein 75 kDa, mitochondrial 10131 reviewed Chaperone
Q13085 BXGT013309 Acetyl-CoA carboxylase 1 31 reviewed
Q13093 BXGT013310 Platelet-activating factor acetylhydrolase 7941 reviewed Enzyme
Q13148 BXGT013318 TAR DNA-binding protein 43 23435 reviewed
Q13155 BXGT013320 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 7965 reviewed
Q13257 BXGT013333 Mitotic spindle assembly checkpoint protein MAD2A 4085 reviewed
Q13285 BXGT013335 Steroidogenic factor 1 2516 reviewed Nuclear receptor
Q13336 BXGT013343 Urea transporter 1 6563 reviewed Transporter
Q13418 BXGT013351 Integrin-linked protein kinase 3611 reviewed Kinase
Q13427 BXGT013354 Peptidyl-prolyl cis-trans isomerase G 9360 reviewed
Q13501 BXGT013365 Sequestosome-1 8878 reviewed
Q13526 BXGT013369 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 5300 reviewed
Q13535 BXGT013370 Serine/threonine-protein kinase ATR 545 reviewed Kinase
Q13547 BXGT013373 Histone deacetylase 1 3065 reviewed Epigenetic regulator
Q13563 BXGT013377 Polycystin-2 5311 reviewed Ion channel
Q13627 BXGT013385 Dual specificity tyrosine-phosphorylation-regulated kinase 1A 1859 reviewed Kinase
Q14114 BXGT013441 Low-density lipoprotein receptor-related protein 8 7804 reviewed
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14451 BXGT013471 Growth factor receptor-bound protein 7 2886 reviewed Receptor
Q14498 BXGT013475 RNA-binding protein 39 9584 reviewed
Q14524 BXGT013478 Sodium channel protein type 5 subunit alpha 6331 reviewed Ion channel
Q15046 BXGT013527 Lysine--tRNA ligase 3735 reviewed Enzyme
Q15149 BXGT013547 Plectin 5339 reviewed Cellular structure
Q15392 BXGT013566 Delta(24)-sterol reductase 1718 reviewed Enzyme
Q15431 BXGT013571 Synaptonemal complex protein 1 6847 reviewed
Q15493 BXGT013575 Regucalcin 9104 reviewed Enzyme
Q15599 BXGT013583 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 9351 reviewed
Q15758 BXGT013594 Neutral amino acid transporter B(0) 6510 reviewed Transporter
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16549 BXGT013637 Proprotein convertase subtilisin/kexin type 7 9159 reviewed
Q16611 BXGT013644 Bcl-2 homologous antagonist/killer 578 reviewed Signaling
Q16637 BXGT013646 Survival motor neuron protein 6607 reviewed Epigenetic regulator
Q16658 BXGT013651 Fascin 6624 reviewed Cellular structure
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16674 BXGT013655 Melanoma-derived growth regulatory protein 8190 reviewed
Q16678 BXGT013656 Cytochrome P450 1B1 1545 reviewed Enzyme
Q16698 BXGT013659 2,4-dienoyl-CoA reductase, mitochondrial 1666 reviewed Enzyme
Q16881 BXGT013688 Thioredoxin reductase 1, cytoplasmic 7296 reviewed Enzyme
Q30201 BXGT014297 Hereditary hemochromatosis protein 3077 reviewed
Q4U2R8 BXGT014891 Solute carrier family 22 member 6 9356 reviewed Transporter
Q5S007 BXGT015650 Leucine-rich repeat serine/threonine-protein kinase 2 120892 reviewed Kinase
Q5TFQ8 BXGT015855 Signal-regulatory protein beta-1 isoform 3 10326 reviewed
Q6EIG7 BXGT016267 C-type lectin domain family 6 member A 93978 reviewed Receptor
Q6N021 BXGT016378 Methylcytosine dioxygenase TET2 54790 reviewed
Q6PI48 BXGT016471 Aspartate--tRNA ligase, mitochondrial 55157 reviewed Enzyme
Q6PL18 BXGT016479 ATPase family AAA domain-containing protein 2 29028 reviewed Epigenetic regulator
Q6UWY2 BXGT016570 Serine protease 57 400668 reviewed
Q6ZQY3 BXGT016636 Acidic amino acid decarboxylase GADL1 339896 reviewed
Q76LX8 BXGT016870 A disintegrin and metalloproteinase with thrombospondin motifs 13 11093 reviewed Enzyme
Q7RTT9 BXGT017086 Equilibrative nucleoside transporter 4 222962 reviewed Transporter
Q86TM3 BXGT017607 Probable ATP-dependent RNA helicase DDX53 168400 reviewed
Q86VQ6 BXGT017620 Thioredoxin reductase 3 114112 reviewed Enzyme
Q86VW1 BXGT017621 Solute carrier family 22 member 16 85413 reviewed Transporter
Q86YC2 BXGT017633 Partner and localizer of BRCA2 79728 reviewed
Q8N5H7 BXGT018518 SH2 domain-containing protein 3C 10044 reviewed
Q8NBJ7 BXGT018537 Inactive C-alpha-formylglycine-generating enzyme 2 25870 reviewed
Q8NCC3 BXGT018546 Group XV phospholipase A2 23659 reviewed Enzyme
Q8TD30 BXGT018805 Alanine aminotransferase 2 84706 reviewed Enzyme
Q8TDQ0 BXGT018810 Hepatitis A virus cellular receptor 2 84868 reviewed
Q8WY64 BXGT019017 E3 ubiquitin-protein ligase MYLIP 29116 reviewed
Q8WZ42 BXGT019023 Titin 7273 reviewed Kinase
Q92859 BXGT019386 Neogenin 4756 reviewed
Q92887 BXGT019389 Canalicular multispecific organic anion transporter 1 1244 reviewed Transporter
Q96A70 BXGT019615 Antizyme inhibitor 2 113451 reviewed Enzyme
Q96D31 BXGT019635 Calcium release-activated calcium channel protein 1 84876 reviewed Ion channel
Q96D42 BXGT019636 Hepatitis A virus cellular receptor 1 26762 reviewed
Q96EP1 BXGT019651 E3 ubiquitin-protein ligase CHFR 55743 reviewed Enzyme
Q96FL8 BXGT019660 Multidrug and toxin extrusion protein 1 55244 reviewed Transporter
Q96IV0 BXGT019677 Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase 55768 reviewed Enzyme
Q96IY4 BXGT019678 Carboxypeptidase B2 1361 reviewed Enzyme
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q96SB4 BXGT019740 SRSF protein kinase 1 6732 reviewed Kinase
Q96SW2 BXGT019743 Protein cereblon 51185 reviewed Enzyme
Q96T60 BXGT019745 Bifunctional polynucleotide phosphatase/kinase 11284 reviewed
Q99497 BXGT019926 Protein/nucleic acid deglycase DJ-1 11315 reviewed Enzyme
Q99593 BXGT019939 T-box transcription factor TBX5 6910 reviewed Transcription factor
Q99653 BXGT019945 Calcineurin B homologous protein 1 11261 reviewed
Q99700 BXGT019949 Ataxin-2 6311 reviewed Nucleic acid binding
Q99720 BXGT019955 Sigma non-opioid intracellular receptor 1 10280 reviewed
Q99814 BXGT019965 Endothelial PAS domain-containing protein 1 2034 reviewed Transcription factor
Q99816 BXGT019966 Tumor susceptibility gene 101 protein 7251 reviewed Enzyme
Q99829 BXGT019968 Copine-1 8904 reviewed
Q99836 BXGT019970 Myeloid differentiation primary response protein MyD88 4615 reviewed Enzyme modulator
Q99933 BXGT019976 BAG family molecular chaperone regulator 1 573 reviewed
Q9BQ65 BXGT020107 U6 snRNA phosphodiesterase 79650 reviewed
Q9BQI3 BXGT020113 Eukaryotic translation initiation factor 2-alpha kinase 1 27102 reviewed Kinase
Q9BS40 BXGT020121 Latexin 56925 reviewed
Q9BXL7 BXGT020171 Caspase recruitment domain-containing protein 11 84433 reviewed
Q9BY41 BXGT020180 Histone deacetylase 8 55869 reviewed Epigenetic regulator
Q9BYT8 BXGT020190 Neurolysin, mitochondrial 57486 reviewed Enzyme
Q9BZS1 BXGT020203 Forkhead box protein P3 50943 reviewed
Q9C000 BXGT020206 NACHT, LRR and PYD domains-containing protein 1 22861 reviewed
Q9GZR1 BXGT020423 Sentrin-specific protease 6 26054 reviewed Enzyme
Q9H3P7 BXGT020464 Golgi resident protein GCP60 64746 reviewed
Q9H4A3 BXGT020473 Serine/threonine-protein kinase WNK1 65125 reviewed Kinase
Q9H9B1 BXGT020501 Histone-lysine N-methyltransferase EHMT1 79813 reviewed Epigenetic regulator
Q9HA77 BXGT020504 Probable cysteine--tRNA ligase, mitochondrial 79587 reviewed Enzyme
Q9HAS3 BXGT020507 Solute carrier family 28 member 3 64078 reviewed Transporter
Q9NP58 BXGT021143 ATP-binding cassette sub-family B member 6, mitochondrial 10058 reviewed Transporter
Q9NR12 BXGT021174 PDZ and LIM domain protein 7 9260 reviewed Cellular structure
Q9NR19 BXGT021175 Acetyl-coenzyme A synthetase, cytoplasmic 55902 reviewed Enzyme
Q9NZ08 BXGT021266 Endoplasmic reticulum aminopeptidase 1 51752 reviewed Enzyme
Q9NZ45 BXGT021269 CDGSH iron-sulfur domain-containing protein 1 55847 reviewed
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9UBC3 BXGT021650 DNA (cytosine-5)-methyltransferase 3B 1789 reviewed
Q9UER7 BXGT021672 Death domain-associated protein 6 1616 reviewed
Q9UHD8 BXGT021698 Septin-9 10801 reviewed Enzyme modulator
Q9UKU7 BXGT021749 Isobutyryl-CoA dehydrogenase, mitochondrial 27034 reviewed Enzyme
Q9UM73 BXGT021773 ALK tyrosine kinase receptor 238 reviewed Kinase
Q9UNQ0 BXGT021792 ATP-binding cassette sub-family G member 2 9429 reviewed Transporter
Q9UQ84 BXGT021807 Exonuclease 1 9156 reviewed Enzyme
Q9Y2Q3 BXGT022242 Glutathione S-transferase kappa 1 373156 reviewed
Q9Y5N1 BXGT022297 Histamine H3 receptor 11255 reviewed G-protein coupled receptor
Q9Y5X4 BXGT022306 Photoreceptor-specific nuclear receptor 10002 reviewed Nuclear receptor
Q9Y617 BXGT022314 Phosphoserine aminotransferase 29968 reviewed
Q9Y646 BXGT022317 Carboxypeptidase Q 10404 reviewed Enzyme
Q9Y6N9 BXGT022337 Harmonin 10083 reviewed Cellular structure
P04439 BXGT022649 HLA class I histocompatibility antigen, A-3 alpha chain 3105 reviewed
P43146 BXGT022852 Netrin receptor DCC 1630 reviewed
P00738 BXGT022874 Haptoglobin 3240 reviewed Enzyme
Q9UNS1 BXGT022882 Protein timeless homolog 8914 reviewed
P16284 BXGT022972 Platelet endothelial cell adhesion molecule 5175 reviewed Cell adhesion
O00308 BXGT023349 NEDD4-like E3 ubiquitin-protein ligase WWP2 11060 reviewed Enzyme
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
Q9H8S9 BXGT023504 MOB kinase activator 1A 55233 reviewed Enzyme modulator
Q13007 BXGT023883 Interleukin-24 11009 reviewed
Q9NZM1 BXGT023948 Myoferlin 26509 reviewed Transporter
Q5T2W1 BXGT023979 Na(+)/H(+) exchange regulatory cofactor NHE-RF3 5174 reviewed
Q14258 BXGT024016 E3 ubiquitin/ISG15 ligase TRIM25 7706 reviewed
Q9BQQ3 BXGT024065 Golgi reassembly-stacking protein 1 64689 reviewed
P63167 BXGT024120 Dynein light chain 1, cytoplasmic 8655 reviewed Cellular structure
Q9UKP6 BXGT024239 Urotensin-2 receptor 2837 reviewed G-protein coupled receptor
Q9H0M0 BXGT024419 NEDD4-like E3 ubiquitin-protein ligase WWP1 11059 reviewed Enzyme
P21926 BXGT024578 CD9 antigen 928 reviewed
Q7Z6A9 BXGT025024 B- and T-lymphocyte attenuator 151888 reviewed
Q9GZV5 BXGT025439 WW domain-containing transcription regulator protein 1 25937 reviewed Enzyme modulator
O14649 BXGT025486 Potassium channel subfamily K member 3 3777 reviewed Ion channel
Q8TCJ2 BXGT025533 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B 201595 reviewed Enzyme
Q969H8 BXGT025606 Myeloid-derived growth factor 56005 reviewed
Q05086 BXGT025648 Ubiquitin-protein ligase E3A 7337 reviewed
Q9UQE7 BXGT025899 Structural maintenance of chromosomes protein 3 9126 reviewed
Q9UKB1 BXGT025928 F-box/WD repeat-containing protein 11 23291 reviewed
P11836 BXGT025994 B-lymphocyte antigen CD20 931 reviewed Receptor
V9HWB9 BXGT026149 L-lactate dehydrogenase 3939 unreviewed
P07320 BXGT026150 Gamma-crystallin D 1421 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease