Showing entry for Hypertriglyceridemia


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD001432
Disease NameHypertriglyceridemia
Disease CUI IdC0020557
MeSH Codes C18  
Disease Class NameNutritional and Metabolic Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00767 BXGT003949 Acyl-CoA desaturase 6319 reviewed
O14788 BXGT004100 Tumor necrosis factor ligand superfamily member 11 8600 reviewed Signaling
O14920 BXGT004110 Inhibitor of nuclear factor kappa-B kinase subunit beta 3551 reviewed Kinase
O15120 BXGT004129 1-acyl-sn-glycerol-3-phosphate acyltransferase beta 10555 reviewed
O43557 BXGT004600 Tumor necrosis factor ligand superfamily member 14 8740 reviewed Signaling
O60240 BXGT004860 Perilipin-1 5346 reviewed
O60313 BXGT004871 Dynamin-like 120 kDa protein, mitochondrial 4976 reviewed Enzyme modulator
O60603 BXGT004887 Toll-like receptor 2 7097 reviewed
O75223 BXGT005106 Gamma-glutamylcyclotransferase 79017 reviewed
O75581 BXGT005136 Low-density lipoprotein receptor-related protein 6 4040 reviewed
O75844 BXGT005156 CAAX prenyl protease 1 homolog 10269 reviewed Enzyme
O76074 BXGT005174 cGMP-specific 3',5'-cyclic phosphodiesterase 8654 reviewed
O76082 BXGT005175 Solute carrier family 22 member 5 6584 reviewed Transporter
O95139 BXGT005349 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 4712 reviewed
O95470 BXGT005382 Sphingosine-1-phosphate lyase 1 8879 reviewed
O95477 BXGT005383 Phospholipid-transporting ATPase ABCA1 19 reviewed Transporter
O95750 BXGT005395 Fibroblast growth factor 19 9965 reviewed Signaling
O95864 BXGT005403 Acyl-CoA 6-desaturase 9415 reviewed
P00505 BXGT005560 Aspartate aminotransferase, mitochondrial 2806 reviewed
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01024 BXGT005719 Complement C3 718 reviewed Enzyme modulator
P01034 BXGT005721 Cystatin-C 1471 reviewed
P01100 BXGT005727 Proto-oncogene c-Fos 2353 reviewed Transcription factor
P01130 BXGT005735 Low-density lipoprotein receptor 3949 reviewed
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01189 BXGT005742 Pro-opiomelanocortin 5443 reviewed
P01275 BXGT005747 Glucagon 2641 reviewed
P01303 BXGT005748 Pro-neuropeptide Y 4852 reviewed Signaling
P01308 BXGT005749 Insulin 3630 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02545 BXGT005889 Prelamin-A/C 4000 reviewed
P02647 BXGT005908 Apolipoprotein A-I 335 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02652 BXGT005910 Apolipoprotein A-II 336 reviewed Transporter
P02654 BXGT005911 Apolipoprotein C-I 341 reviewed
P02655 BXGT005912 Apolipoprotein C-II 344 reviewed
P02656 BXGT005913 Apolipoprotein C-III 345 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02753 BXGT005945 Retinol-binding protein 4 5950 reviewed Transporter
P02765 BXGT005952 Alpha-2-HS-glycoprotein 197 reviewed Enzyme modulator
P02766 BXGT005953 Transthyretin 7276 reviewed Transporter
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P02788 BXGT005963 Lactotransferrin 4057 reviewed Enzyme
P04035 BXGT006129 3-hydroxy-3-methylglutaryl-coenzyme A reductase 3156 reviewed
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04150 BXGT006154 Glucocorticoid receptor 2908 reviewed Nuclear receptor
P04180 BXGT006164 Phosphatidylcholine-sterol acyltransferase 3931 reviewed Enzyme
P04275 BXGT006180 von Willebrand factor 7450 reviewed Enzyme modulator
P04278 BXGT006182 Sex hormone-binding globulin 6462 reviewed
P05107 BXGT006316 Integrin beta-2 3689 reviewed Receptor
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05181 BXGT006337 Cytochrome P450 2E1 1571 reviewed
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P06276 BXGT006430 Cholinesterase 590 reviewed
P06727 BXGT006485 Apolipoprotein A-IV 337 reviewed
P06731 BXGT006488 Carcinoembryonic antigen-related cell adhesion molecule 5 1048 reviewed
P06737 BXGT006492 Glycogen phosphorylase, liver form 5836 reviewed Enzyme
P06744 BXGT006494 Glucose-6-phosphate isomerase 2821 reviewed Enzyme
P06858 BXGT006515 Lipoprotein lipase 4023 reviewed Enzyme
P07203 BXGT006566 Glutathione peroxidase 1 2876 reviewed Enzyme
P07288 BXGT006591 Prostate-specific antigen 354 reviewed Enzyme
P07327 BXGT006598 Alcohol dehydrogenase 1A 124 reviewed Enzyme
P07477 BXGT006629 Trypsin-1 5644 reviewed Enzyme
P07550 BXGT006636 Beta-2 adrenergic receptor 154 reviewed G-protein coupled receptor
P08235 BXGT006751 Mineralocorticoid receptor 4306 reviewed Nuclear receptor
P08779 BXGT006824 Keratin, type I cytoskeletal 16 3868 reviewed
P08887 BXGT006835 Interleukin-6 receptor subunit alpha 3570 reviewed Signaling
P09455 BXGT006890 Retinol-binding protein 1 5947 reviewed
P09466 BXGT006892 Glycodelin 5047 reviewed Enzyme
P09488 BXGT006899 Glutathione S-transferase Mu 1 2944 reviewed
P11021 BXGT007644 Endoplasmic reticulum chaperone BiP 3309 reviewed
P11413 BXGT007701 Glucose-6-phosphate 1-dehydrogenase 2539 reviewed Enzyme
P11597 BXGT007727 Cholesteryl ester transfer protein 1071 reviewed
P12104 BXGT007773 Fatty acid-binding protein, intestinal 2169 reviewed
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P13569 BXGT007923 Cystic fibrosis transmembrane conductance regulator 1080 reviewed Ion channel
P13945 BXGT007972 Beta-3 adrenergic receptor 155 reviewed G-protein coupled receptor
P15121 BXGT008083 Aldo-keto reductase family 1 member B1 231 reviewed Enzyme
P15735 BXGT008151 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform 5261 reviewed Kinase
P16070 BXGT008186 CD44 antigen 960 reviewed
P16671 BXGT008255 Platelet glycoprotein 4 948 reviewed Receptor
P17405 BXGT008304 Sphingomyelin phosphodiesterase 6609 reviewed Enzyme
P17643 BXGT008323 5,6-dihydroxyindole-2-carboxylic acid oxidase 7306 reviewed Enzyme
P17936 BXGT008357 Insulin-like growth factor-binding protein 3 3486 reviewed Enzyme modulator
P18031 BXGT008369 Tyrosine-protein phosphatase non-receptor type 1 5770 reviewed
P19320 BXGT008470 Vascular cell adhesion protein 1 7412 reviewed
P21359 BXGT008640 Neurofibromin 4763 reviewed Enzyme modulator
P21695 BXGT008682 Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic 2819 reviewed Enzyme
P21980 BXGT008715 Protein-glutamine gamma-glutamyltransferase 2 7052 reviewed Enzyme
P22413 BXGT008764 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 5167 reviewed Enzyme
P22680 BXGT008794 Cholesterol 7-alpha-monooxygenase 1581 reviewed Enzyme
P22830 BXGT008809 Ferrochelatase, mitochondrial 2235 reviewed Enzyme
P23141 BXGT008830 Liver carboxylesterase 1 1066 reviewed Enzyme
P23786 BXGT008906 Carnitine O-palmitoyltransferase 2, mitochondrial 1376 reviewed Enzyme
P24298 BXGT008960 Alanine aminotransferase 1 2875 reviewed Enzyme
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 1786 reviewed Epigenetic regulator
P27169 BXGT009161 Serum paraoxonase/arylesterase 1 5444 reviewed
P27487 BXGT009187 Dipeptidyl peptidase 4 1803 reviewed Enzyme
P27540 BXGT009190 Aryl hydrocarbon receptor nuclear translocator 405 reviewed Transcription factor
P27708 BXGT009202 CAD protein 790 reviewed Enzyme
P28070 BXGT009230 Proteasome subunit beta type-4 5692 reviewed
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P29372 BXGT009336 DNA-3-methyladenine glycosylase 4350 reviewed Enzyme
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P30556 BXGT009441 Type-1 angiotensin II receptor 185 reviewed G-protein coupled receptor
P30711 BXGT009460 Glutathione S-transferase theta-1 2952 reviewed
P31639 BXGT009556 Sodium/glucose cotransporter 2 6524 reviewed Transporter
P31751 BXGT009576 RAC-beta serine/threonine-protein kinase 208 reviewed Kinase
P32245 BXGT009614 Melanocortin receptor 4 4160 reviewed G-protein coupled receptor
P35557 BXGT009846 Glucokinase 2645 reviewed Kinase
P35573 BXGT009850 Glycogen debranching enzyme 178 reviewed Enzyme
P35610 BXGT009855 Sterol O-acyltransferase 1 6646 reviewed Enzyme
P36956 BXGT009947 Sterol regulatory element-binding protein 1 6720 reviewed
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P38571 BXGT010054 Lysosomal acid lipase/cholesteryl ester hydrolase 3988 reviewed Enzyme
P40189 BXGT010164 Interleukin-6 receptor subunit beta 3572 reviewed Signaling
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41180 BXGT010230 Extracellular calcium-sensing receptor 846 reviewed G-protein coupled receptor
P41235 BXGT010241 Hepatocyte nuclear factor 4-alpha 3172 reviewed Nuclear receptor
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P43220 BXGT010367 Glucagon-like peptide 1 receptor 2740 reviewed G-protein coupled receptor
P46019 BXGT010498 Phosphorylase b kinase regulatory subunit alpha, liver isoform 5256 reviewed Kinase
P46059 BXGT010500 Solute carrier family 15 member 1 6564 reviewed Transporter
P48357 BXGT010627 Leptin receptor 3953 reviewed Signaling
P48728 BXGT010654 Aminomethyltransferase, mitochondrial 275 reviewed
P49638 BXGT010720 Alpha-tocopherol transfer protein 7274 reviewed Transporter
P50416 BXGT010797 Carnitine O-palmitoyltransferase 1, liver isoform 1374 reviewed Enzyme
P51843 BXGT010897 Nuclear receptor subfamily 0 group B member 1 190 reviewed Nuclear receptor
P53985 BXGT011022 Monocarboxylate transporter 1 6566 reviewed Transporter
P55157 BXGT011108 Microsomal triglyceride transfer protein large subunit 4547 reviewed Transporter
P60568 BXGT011315 Interleukin-2 3558 reviewed
P78504 BXGT011844 Protein jagged-1 182 reviewed
P98155 BXGT012226 Very low-density lipoprotein receptor 7436 reviewed
P98170 BXGT012231 E3 ubiquitin-protein ligase XIAP 331 reviewed Enzyme modulator
Q02750 BXGT012662 Dual specificity mitogen-activated protein kinase kinase 1 5604 reviewed Kinase
Q05513 BXGT012820 Protein kinase C zeta type 5590 reviewed Kinase
Q07108 BXGT012919 Early activation antigen CD69 969 reviewed
Q07869 BXGT012945 Peroxisome proliferator-activated receptor alpha 5465 reviewed Nuclear receptor
Q09428 BXGT013036 ATP-binding cassette sub-family C member 8 6833 reviewed Transporter
Q0VD83 BXGT013179 Apolipoprotein B receptor 55911 reviewed
Q10471 BXGT013201 Polypeptide N-acetylgalactosaminyltransferase 2 2590 reviewed Enzyme
Q12772 BXGT013262 Sterol regulatory element-binding protein 2 6721 reviewed
Q12778 BXGT013263 Forkhead box protein O1 2308 reviewed
Q12908 BXGT013278 Ileal sodium/bile acid cotransporter 6555 reviewed Transporter
Q13085 BXGT013309 Acetyl-CoA carboxylase 1 31 reviewed
Q13093 BXGT013310 Platelet-activating factor acetylhydrolase 7941 reviewed Enzyme
Q13133 BXGT013315 Oxysterols receptor LXR-alpha 10062 reviewed Nuclear receptor
Q13426 BXGT013353 DNA repair protein XRCC4 7518 reviewed
Q13451 BXGT013356 Peptidyl-prolyl cis-trans isomerase FKBP5 2289 reviewed Enzyme
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14397 BXGT013467 Glucokinase regulatory protein 2646 reviewed
Q15063 BXGT013531 Periostin 10631 reviewed Signaling
Q15833 BXGT013605 Syntaxin-binding protein 2 6813 reviewed Transporter
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q2MKA7 BXGT014140 R-spondin-1 284654 reviewed
Q6VAB6 BXGT016576 Kinase suppressor of Ras 2 283455 reviewed Kinase
Q7L266 BXGT016993 Isoaspartyl peptidase/L-asparaginase 80150 reviewed Enzyme
Q8IVS2 BXGT018349 Malonyl-CoA-acyl carrier protein transacylase, mitochondrial 27349 reviewed
Q8NBP7 BXGT018541 Proprotein convertase subtilisin/kexin type 9 255738 reviewed Enzyme
Q8NEM0 BXGT018555 Microcephalin 79648 reviewed Nucleic acid binding
Q8TDQ0 BXGT018810 Hepatitis A virus cellular receptor 2 84868 reviewed
Q8TE23 BXGT018819 Taste receptor type 1 member 2 80834 reviewed G-protein coupled receptor
Q8WTS1 BXGT018985 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 51099 reviewed
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q99707 BXGT019952 Methionine synthase 4548 reviewed
Q99895 BXGT019974 Chymotrypsin-C 11330 reviewed
Q9BWD1 BXGT020152 Acetyl-CoA acetyltransferase, cytosolic 39 reviewed Enzyme
Q9H3M7 BXGT020462 Thioredoxin-interacting protein 10628 reviewed
Q9H9B1 BXGT020501 Histone-lysine N-methyltransferase EHMT1 79813 reviewed Epigenetic regulator
Q9UBK8 BXGT021655 Methionine synthase reductase 4552 reviewed
Q9UBM7 BXGT021657 7-dehydrocholesterol reductase 1717 reviewed Enzyme
Q9UJS0 BXGT021727 Calcium-binding mitochondrial carrier protein Aralar2 10165 reviewed Transporter
Q99958 BXGT023732 Forkhead box protein C2 2303 reviewed Transcription factor
P51608 BXGT025073 Methyl-CpG-binding protein 2 4204 reviewed Epigenetic regulator
A8K7I4 BXGT025277 Calcium-activated chloride channel regulator 1 1179 reviewed Ion channel
Q9BY76 BXGT025687 Angiopoietin-related protein 4 51129 reviewed Signaling
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease