Showing entry for Receptor-type tyrosine-protein phosphatase beta


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT008869
Protein NameReceptor-type tyrosine-protein phosphatase beta
Uniport IdP23467
GenePTPRB
Gene Id5787
Domainfn3; Y_phosphatase
Pfam PF00041   PF00102  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
4. Cellular Processes 4.3 Cellular community - eukaryotes hsa04520 Adherens junction
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0001525 angiogenesis
Biological Process GO:0016311 dephosphorylation
Biological Process GO:0043312 neutrophil degranulation
Biological Process GO:1990264 peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity
Biological Process GO:0006796 phosphate-containing compound metabolic process
Biological Process GO:0006470 protein dephosphorylation
molecular function GO:0045296 cadherin binding
molecular function GO:0005001 transmembrane receptor protein tyrosine phosphatase activity
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0043235 receptor complex
cellular component GO:0035579 specific granule membrane
cellular component GO:0070821 tertiary granule membrane
Reactome
Pathway Id Pathway Name
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-6798695 Neutrophil degranulation
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0017601 BXGD001125 Glaucoma Eye Diseases
C0018923 BXGD001248 Hemangiosarcoma Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0041296 BXGD002903 Tuberculosis Infections
C0042373 BXGD002978 Vascular Diseases Cardiovascular Diseases
C0152013 BXGD003516 Adenocarcinoma of lung (disorder) Neoplasms
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0278592 BXGD006544 Adult Angiosarcoma Neoplasms
C0279988 BXGD006707 Childhood Angiosarcoma Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0730328 BXGD009959 Central Serous Chorioretinopathy Eye Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1510472 BXGD013170 Drug Dependence Chemically-Induced Disorders; Mental Disorders
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
BXGC0003705 Chloride 35.45
BXGC0009231 ent-Epicatechin-(4alpha->8)-catechin 578.52
BXGC0026123 Biotin 244.09
BXGC0028589 5,6,7,8-Tetrahydroxy-2-(4-Hydroxyphenyl)Chromen-4-One 302.04
BXGC0043088 Pyridoxal Phosphate 247.02
BXGC0049447 acetate 59.01
BXGC0050184 Myricitrin 464.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein