adisease

Showing entry for Glaucoma

General Disease Information
BXGD Id	BXGD001125
Disease Name	Glaucoma
Disease CUI Id	C0017601
MeSH Codes	C11
Disease Class Name	Eye Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0000478
Human Phenotype Ontology Term	Abnormality of the eye
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A4D126	BXGT001208	D-ribitol-5-phosphate cytidylyltransferase	729920	reviewed
F7VJQ1	BXGT003310	Alternative prion protein	5621	reviewed
O00182	BXGT003889	Galectin-9	3965	reviewed	Signaling
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O00311	BXGT003908	Cell division cycle 7-related protein kinase	8317	reviewed	Kinase
O00329	BXGT003909	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	5293	reviewed	Kinase
O00429	BXGT003919	Dynamin-1-like protein	10059	reviewed	Enzyme modulator
O00443	BXGT003920	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha	5286	reviewed	Kinase
O00444	BXGT003921	Serine/threonine-protein kinase PLK4	10733	reviewed	Kinase
O00519	BXGT003934	Fatty-acid amide hydrolase 1	2166	reviewed
O15075	BXGT004124	Serine/threonine-protein kinase DCLK1	9201	reviewed	Kinase
O15123	BXGT004130	Angiopoietin-2	285	reviewed	Signaling
O15197	BXGT004136	Ephrin type-B receptor 6	2051	reviewed	Kinase
O43557	BXGT004600	Tumor necrosis factor ligand superfamily member 14	8740	reviewed	Signaling
O43570	BXGT004601	Carbonic anhydrase 12	771	reviewed
O43639	BXGT004608	Cytoplasmic protein NCK2	8440	reviewed
O43683	BXGT004614	Mitotic checkpoint serine/threonine-protein kinase BUB1	699	reviewed	Kinase
O60313	BXGT004871	Dynamin-like 120 kDa protein, mitochondrial	4976	reviewed	Enzyme modulator
O60566	BXGT004884	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta	701	reviewed	Kinase
O60760	BXGT004899	Hematopoietic prostaglandin D synthase	27306	reviewed
O75116	BXGT005100	Rho-associated protein kinase 2	9475	reviewed	Kinase
O75643	BXGT005142	U5 small nuclear ribonucleoprotein 200 kDa helicase	23020	reviewed
O94766	BXGT005330	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3	26229	reviewed	Enzyme
O95237	BXGT005361	Lecithin retinol acyltransferase	9227	reviewed
O95477	BXGT005383	Phospholipid-transporting ATPase ABCA1	19	reviewed	Transporter
O95786	BXGT005396	Probable ATP-dependent RNA helicase DDX58	23586	reviewed
P00156	BXGT005469	Cytochrome b	4519	reviewed
P00352	BXGT005510	Retinal dehydrogenase 1	216	reviewed	Enzyme
P00441	BXGT005540	Superoxide dismutase [Cu-Zn]	6647	reviewed	Enzyme
P00450	BXGT005544	Ceruloplasmin	1356	reviewed	Enzyme
P00740	BXGT005634	Coagulation factor IX	2158	reviewed	Enzyme
P00747	BXGT005639	Plasminogen	5340	reviewed	Enzyme
P00918	BXGT005690	Carbonic anhydrase 2	760	reviewed
P01009	BXGT005714	Alpha-1-antitrypsin	5265	reviewed	Enzyme modulator
P01019	BXGT005717	Angiotensinogen	183	reviewed	Enzyme modulator
P01024	BXGT005719	Complement C3	718	reviewed	Enzyme modulator
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01138	BXGT005738	Beta-nerve growth factor	4803	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01589	BXGT005773	Interleukin-2 receptor subunit alpha	3559	reviewed	Receptor
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P02452	BXGT005878	Collagen alpha-1(I) chain	1277	reviewed
P02458	BXGT005879	Collagen alpha-1(II) chain	1280	reviewed
P02461	BXGT005880	Collagen alpha-1(III) chain	1281	reviewed
P02462	BXGT005881	Collagen alpha-1(IV) chain	1282	reviewed
P02511	BXGT005885	Alpha-crystallin B chain	1410	reviewed
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02743	BXGT005937	Serum amyloid P-component	325	reviewed
P02751	BXGT005943	Fibronectin	2335	reviewed	Signaling
P02766	BXGT005953	Transthyretin	7276	reviewed	Transporter
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P02786	BXGT005961	Transferrin receptor protein 1	7037	reviewed	Enzyme
P02818	BXGT005969	Osteocalcin	632	reviewed
P03956	BXGT006120	Interstitial collagenase	4312	reviewed	Enzyme
P04003	BXGT006124	C4b-binding protein alpha chain	722	reviewed
P04004	BXGT006125	Vitronectin	7448	reviewed
P04150	BXGT006154	Glucocorticoid receptor	2908	reviewed	Nuclear receptor
P04156	BXGT006156	Major prion protein	5621	reviewed
P04179	BXGT006163	Superoxide dismutase [Mn], mitochondrial	6648	reviewed	Enzyme
P04271	BXGT006177	Protein S100-B	6285	reviewed	Calcium-binding protein
P04275	BXGT006180	von Willebrand factor	7450	reviewed	Enzyme modulator
P04629	BXGT006239	High affinity nerve growth factor receptor	4914	reviewed	Kinase
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P04731	BXGT006251	Metallothionein-1A	4489	reviewed
P04732	BXGT006252	Metallothionein-1E	4493	reviewed
P04733	BXGT006253	Metallothionein-1F	4494	reviewed
P04839	BXGT006273	Cytochrome b-245 heavy chain	1536	reviewed	Ion channel
P05187	BXGT006339	Alkaline phosphatase, placental type	250	reviewed	Enzyme
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06276	BXGT006430	Cholinesterase	590	reviewed
P06280	BXGT006433	Alpha-galactosidase A	2717	reviewed
P06396	BXGT006435	Gelsolin	2934	reviewed	Cellular structure
P07101	BXGT006547	Tyrosine 3-monooxygenase	7054	reviewed
P07438	BXGT006625	Metallothionein-1B	4490	reviewed
P07550	BXGT006636	Beta-2 adrenergic receptor	154	reviewed	G-protein coupled receptor
P07741	BXGT006666	Adenine phosphoribosyltransferase	353	reviewed
P07996	BXGT006710	Thrombospondin-1	7057	reviewed
P08100	BXGT006725	Rhodopsin	6010	reviewed	G-protein coupled receptor
P08138	BXGT006729	Tumor necrosis factor receptor superfamily member 16	4804	reviewed	Receptor
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08254	BXGT006758	Stromelysin-1	4314	reviewed	Enzyme
P08758	BXGT006821	Annexin A5	308	reviewed
P08908	BXGT006837	5-hydroxytryptamine receptor 1A	3350	reviewed	G-protein coupled receptor
P08922	BXGT006843	Proto-oncogene tyrosine-protein kinase ROS	6098	reviewed	Kinase
P09172	BXGT006865	Dopamine beta-hydroxylase	1621	reviewed
P09211	BXGT006869	Glutathione S-transferase P	2950	reviewed
P09486	BXGT006897	SPARC	6678	reviewed	Signaling
P09488	BXGT006899	Glutathione S-transferase Mu 1	2944	reviewed
P09619	BXGT006911	Platelet-derived growth factor receptor beta	5159	reviewed	Kinase
P09923	BXGT006942	Intestinal-type alkaline phosphatase	248	reviewed	Enzyme
P0DMV8	BXGT007509	Heat shock 70 kDa protein 1A	3304	reviewed
P0DMV9	BXGT007510	Heat shock 70 kDa protein 1B	3304	reviewed
P0DN79	BXGT007511	Cystathionine beta-synthase-like protein	875	reviewed
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10599	BXGT007583	Thioredoxin	7295	reviewed
P10636	BXGT007596	Microtubule-associated protein tau	4137	reviewed
P10745	BXGT007608	Retinol-binding protein 3	5949	reviewed
P10809	BXGT007617	60 kDa heat shock protein, mitochondrial	3329	reviewed
P10909	BXGT007630	Clusterin	1191	reviewed
P10997	BXGT007643	Islet amyloid polypeptide	3375	reviewed	Signaling
P11215	BXGT007672	Integrin alpha-M	3684	reviewed
P11308	BXGT007684	Transcriptional regulator ERG	2078	reviewed	Transcription factor
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P11586	BXGT007723	C-1-tetrahydrofolate synthase, cytoplasmic	4522	reviewed	Enzyme
P12235	BXGT007774	ADP/ATP translocase 1	291	reviewed	Transporter
P12271	BXGT007786	Retinaldehyde-binding protein 1	6017	reviewed	Transporter
P12429	BXGT007814	Annexin A3	306	reviewed
P12643	BXGT007830	Bone morphogenetic protein 2	650	reviewed	Signaling
P12724	BXGT007837	Eosinophil cationic protein	6037	reviewed
P13224	BXGT007890	Platelet glycoprotein Ib beta chain	2812	reviewed
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P13612	BXGT007928	Integrin alpha-4	3676	reviewed
P13640	BXGT007935	Metallothionein-1G	4495	reviewed
P14625	BXGT008029	Endoplasmin	7184	reviewed	Chaperone
P14679	BXGT008039	Tyrosinase	7299	reviewed	Enzyme
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P14921	BXGT008068	Protein C-ets-1	2113	reviewed	Transcription factor
P15336	BXGT008109	Cyclic AMP-dependent transcription factor ATF-2	1386	reviewed	Transcription factor
P15529	BXGT008134	Membrane cofactor protein	4179	reviewed
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P15848	BXGT008162	Arylsulfatase B	411	reviewed
P16220	BXGT008206	Cyclic AMP-responsive element-binding protein 1	1385	reviewed
P16442	BXGT008227	Histo-blood group ABO system transferase	28	reviewed	Enzyme
P16499	BXGT008238	Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha	5145	reviewed
P16581	BXGT008245	E-selectin	6401	reviewed
P17516	BXGT008313	Aldo-keto reductase family 1 member C4	1109	reviewed	Enzyme
P17643	BXGT008323	5,6-dihydroxyindole-2-carboxylic acid oxidase	7306	reviewed	Enzyme
P17676	BXGT008327	CCAAT/enhancer-binding protein beta	1051	reviewed	Transcription factor
P17707	BXGT008331	S-adenosylmethionine decarboxylase proenzyme	262	reviewed	Enzyme
P18887	BXGT008437	DNA repair protein XRCC1	7515	reviewed
P19544	BXGT008494	Wilms tumor protein	7490	reviewed	Nucleic acid binding
P19838	BXGT008526	Nuclear factor NF-kappa-B p105 subunit	4790	reviewed	Transcription factor
P19883	BXGT008528	Follistatin	10468	reviewed	Enzyme modulator
P20794	BXGT008600	Serine/threonine-protein kinase MAK	4117	reviewed	Kinase
P20813	BXGT008603	Cytochrome P450 2B6	1555	reviewed
P20839	BXGT008608	Inosine-5'-monophosphate dehydrogenase 1	3614	reviewed	Enzyme
P20936	BXGT008619	Ras GTPase-activating protein 1	5921	reviewed	Enzyme modulator
P21266	BXGT008632	Glutathione S-transferase Mu 3	2947	reviewed
P21359	BXGT008640	Neurofibromin	4763	reviewed	Enzyme modulator
P21397	BXGT008644	Amine oxidase [flavin-containing] A	4128	reviewed
P21554	BXGT008662	Cannabinoid receptor 1	1268	reviewed	G-protein coupled receptor
P21579	BXGT008665	Synaptotagmin-1	6857	reviewed	Transporter
P21964	BXGT008714	Catechol O-methyltransferase	1312	reviewed	Enzyme
P21980	BXGT008715	Protein-glutamine gamma-glutamyltransferase 2	7052	reviewed	Enzyme
P22303	BXGT008751	Acetylcholinesterase	43	reviewed	Enzyme
P22748	BXGT008802	Carbonic anhydrase 4	762	reviewed
P23467	BXGT008869	Receptor-type tyrosine-protein phosphatase beta	5787	reviewed
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P23975	BXGT008935	Sodium-dependent noradrenaline transporter	6530	reviewed	Transporter
P24530	BXGT008975	Endothelin receptor type B	1910	reviewed	G-protein coupled receptor
P25101	BXGT009018	Endothelin-1 receptor	1909	reviewed	G-protein coupled receptor
P25942	BXGT009079	Tumor necrosis factor receptor superfamily member 5	958	reviewed
P27169	BXGT009161	Serum paraoxonase/arylesterase 1	5444	reviewed
P27361	BXGT009176	Mitogen-activated protein kinase 3	5595	reviewed	Kinase
P27986	BXGT009216	Phosphatidylinositol 3-kinase regulatory subunit alpha	5295	reviewed	Kinase
P28161	BXGT009234	Glutathione S-transferase Mu 2	2946	reviewed
P28300	BXGT009243	Protein-lysine 6-oxidase	4015	reviewed
P28845	BXGT009297	Corticosteroid 11-beta-dehydrogenase isozyme 1	3290	reviewed
P29474	BXGT009352	Nitric oxide synthase, endothelial	4846	reviewed
P29973	BXGT009389	cGMP-gated cation channel alpha-1	1259	reviewed	Ion channel
P30041	BXGT009393	Peroxiredoxin-6	9588	reviewed	Enzyme
P30279	BXGT009415	G1/S-specific cyclin-D2	894	reviewed	Enzyme modulator
P30556	BXGT009441	Type-1 angiotensin II receptor	185	reviewed	G-protein coupled receptor
P30711	BXGT009460	Glutathione S-transferase theta-1	2952	reviewed
P31749	BXGT009574	RAC-alpha serine/threonine-protein kinase	207	reviewed	Kinase
P31948	BXGT009590	Stress-induced-phosphoprotein 1	10963	reviewed
P32019	BXGT009595	Type II inositol 1,4,5-trisphosphate 5-phosphatase	3633	reviewed	Enzyme
P32119	BXGT009600	Peroxiredoxin-2	7001	reviewed	Enzyme
P33527	BXGT009728	Multidrug resistance-associated protein 1	4363	reviewed	Transporter
P34932	BXGT009772	Heat shock 70 kDa protein 4	3308	reviewed
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P35414	BXGT009829	Apelin receptor	187	reviewed	G-protein coupled receptor
P35475	BXGT009837	Alpha-L-iduronidase	3425	reviewed	Enzyme
P35520	BXGT009842	Cystathionine beta-synthase	875	reviewed
P35555	BXGT009845	Fibrillin-1	2200	reviewed	Calcium-binding protein
P35858	BXGT009876	Insulin-like growth factor-binding protein complex acid labile subunit	3483	reviewed	Receptor
P35869	BXGT009877	Aryl hydrocarbon receptor	196	reviewed	Transcription factor
P35913	BXGT009879	Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta	5158	reviewed
P35916	BXGT009881	Vascular endothelial growth factor receptor 3	2324	reviewed	Kinase
P36897	BXGT009941	TGF-beta receptor type-1	7046	reviewed	Kinase
P36955	BXGT009946	Pigment epithelium-derived factor	5176	reviewed	Enzyme modulator
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P37840	BXGT010015	Alpha-synuclein	6622	reviewed	Transporter
P38936	BXGT010074	Cyclin-dependent kinase inhibitor 1	1026	reviewed
P39019	BXGT010082	40S ribosomal protein S19	6223	reviewed	Nucleic acid binding
P39060	BXGT010088	Collagen alpha-1(XVIII) chain	80781	reviewed
P40337	BXGT010174	von Hippel-Lindau disease tumor suppressor	7428	reviewed	Enzyme
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P41227	BXGT010238	N-alpha-acetyltransferase 10	8260	reviewed	Enzyme
P41235	BXGT010241	Hepatocyte nuclear factor 4-alpha	3172	reviewed	Nuclear receptor
P41597	BXGT010268	C-C chemokine receptor type 2	729230	reviewed
P42330	BXGT010301	Aldo-keto reductase family 1 member C3	8644	reviewed	Enzyme
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42338	BXGT010303	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	5291	reviewed	Kinase
P42345	BXGT010304	Serine/threonine-protein kinase mTOR	2475	reviewed	Kinase
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P43003	BXGT010347	Excitatory amino acid transporter 1	6507	reviewed	Transporter
P43005	BXGT010349	Excitatory amino acid transporter 3	6505	reviewed	Transporter
P43116	BXGT010357	Prostaglandin E2 receptor EP2 subtype	5732	reviewed	G-protein coupled receptor
P43378	BXGT010383	Tyrosine-protein phosphatase non-receptor type 9	5780	reviewed	Enzyme
P45983	BXGT010494	Mitogen-activated protein kinase 8	5599	reviewed	Kinase
P45984	BXGT010495	Mitogen-activated protein kinase 9	5601	reviewed	Kinase
P46527	BXGT010525	Cyclin-dependent kinase inhibitor 1B	1027	reviewed
P46937	BXGT010554	Transcriptional coactivator YAP1	10413	reviewed	Enzyme modulator
P46939	BXGT010555	Utrophin	7402	reviewed
P47712	BXGT010577	Cytosolic phospholipase A2	5321	reviewed	Enzyme
P48039	BXGT010607	Melatonin receptor type 1A	4543	reviewed	G-protein coupled receptor
P48728	BXGT010654	Aminomethyltransferase, mitochondrial	275	reviewed
P48736	BXGT010658	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	5294	reviewed	Kinase
P48740	BXGT010659	Mannan-binding lectin serine protease 1	5648	reviewed	Enzyme
P49419	BXGT010705	Alpha-aminoadipic semialdehyde dehydrogenase	501	reviewed	Enzyme
P49913	BXGT010761	Cathelicidin antimicrobial peptide	820	reviewed
P50213	BXGT010779	Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial	3419	reviewed	Enzyme
P50542	BXGT010808	Peroxisomal targeting signal 1 receptor	5830	reviewed	Transporter
P50750	BXGT010818	Cyclin-dependent kinase 9	1025	reviewed	Kinase
P51589	BXGT010867	Cytochrome P450 2J2	1573	reviewed
P51955	BXGT010908	Serine/threonine-protein kinase Nek2	4751	reviewed	Kinase
P52732	BXGT010948	Kinesin-like protein KIF11	3832	reviewed	Cellular structure
P53667	BXGT011008	LIM domain kinase 1	3984	reviewed	Kinase
P53779	BXGT011014	Mitogen-activated protein kinase 10	5602	reviewed	Kinase
P54098	BXGT011030	DNA polymerase subunit gamma-1	5428	reviewed	Enzyme
P54289	BXGT011040	Voltage-dependent calcium channel subunit alpha-2/delta-1	781	reviewed	Ion channel
P54762	BXGT011076	Ephrin type-B receptor 1	2047	reviewed	Kinase
P55087	BXGT011105	Aquaporin-4	361	reviewed	Ion channel
P56937	BXGT011205	3-keto-steroid reductase	51478	reviewed
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P62826	BXGT011463	GTP-binding nuclear protein Ran	5901	reviewed	Enzyme modulator
P63010	BXGT011484	AP-2 complex subunit beta	163	reviewed	Transporter
P63092	BXGT011495	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	2778	reviewed
P68871	BXGT011615	Hemoglobin subunit beta	3043	reviewed
P78310	BXGT011830	Coxsackievirus and adenovirus receptor	1525	reviewed
P80188	BXGT011882	Neutrophil gelatinase-associated lipocalin	3934	reviewed	Enzyme
P80294	BXGT011890	Metallothionein-1H	4496	reviewed
P80297	BXGT011891	Metallothionein-1X	4501	reviewed
P82279	BXGT011972	Protein crumbs homolog 1	23418	reviewed
P84022	BXGT012027	Mothers against decapentaplegic homolog 3	4088	reviewed	Transcription factor
Q00604	BXGT012538	Norrin	4693	reviewed
Q01968	BXGT012626	Inositol polyphosphate 5-phosphatase OCRL-1	4952	reviewed	Enzyme
Q02224	BXGT012643	Centromere-associated protein E	1062	reviewed	Cellular structure
Q02763	BXGT012667	Angiopoietin-1 receptor	7010	reviewed	Kinase
Q02809	BXGT012674	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1	5351	reviewed	Enzyme
Q03164	BXGT012700	Histone-lysine N-methyltransferase 2A	4297	reviewed
Q03518	BXGT012723	Antigen peptide transporter 1	6890	reviewed	Transporter
Q04206	BXGT012754	Transcription factor p65	5970	reviewed	Transcription factor
Q04771	BXGT012783	Activin receptor type-1	90	reviewed	Kinase
Q06124	BXGT012856	Tyrosine-protein phosphatase non-receptor type 11	5781	reviewed
Q07812	BXGT012940	Apoptosis regulator BAX	581	reviewed	Signaling
Q07817	BXGT012941	Bcl-2-like protein 1	598	reviewed	Signaling
Q08722	BXGT013002	Leukocyte surface antigen CD47	961	reviewed
Q09472	BXGT013038	Histone acetyltransferase p300	2033	reviewed
Q12778	BXGT013263	Forkhead box protein O1	2308	reviewed
Q12866	BXGT013273	Tyrosine-protein kinase Mer	10461	reviewed	Kinase
Q13485	BXGT013363	Mothers against decapentaplegic homolog 4	4089	reviewed	Transcription factor
Q13501	BXGT013365	Sequestosome-1	8878	reviewed
Q13510	BXGT013367	Acid ceramidase	427	reviewed	Enzyme
Q13535	BXGT013370	Serine/threonine-protein kinase ATR	545	reviewed	Kinase
Q13546	BXGT013372	Receptor-interacting serine/threonine-protein kinase 1	8737	reviewed	Kinase
Q13547	BXGT013373	Histone deacetylase 1	3065	reviewed	Epigenetic regulator
Q13936	BXGT013404	Voltage-dependent L-type calcium channel subunit alpha-1C	775	reviewed	Ion channel
Q14118	BXGT013444	Dystroglycan	1605	reviewed	Receptor
Q14289	BXGT013459	Protein-tyrosine kinase 2-beta	2185	reviewed	Kinase
Q14457	BXGT013472	Beclin-1	8678	reviewed	Enzyme modulator
Q14683	BXGT013500	Structural maintenance of chromosomes protein 1A	8243	reviewed
Q15063	BXGT013531	Periostin	10631	reviewed	Signaling
Q15077	BXGT013533	P2Y purinoceptor 6	5031	reviewed	G-protein coupled receptor
Q15109	BXGT013537	Advanced glycosylation end product-specific receptor	177	reviewed	Receptor
Q15118	BXGT013540	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial	5163	reviewed	Kinase
Q15125	BXGT013543	3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	10682	reviewed	Enzyme
Q15389	BXGT013564	Angiopoietin-1	284	reviewed	Signaling
Q15652	BXGT013587	Probable JmjC domain-containing histone demethylation protein 2C	221037	reviewed
Q15746	BXGT013591	Myosin light chain kinase, smooth muscle	4638	reviewed	Kinase
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
Q16611	BXGT013644	Bcl-2 homologous antagonist/killer	578	reviewed	Signaling
Q16620	BXGT013645	BDNF/NT-3 growth factors receptor	4915	reviewed	Kinase
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q16678	BXGT013656	Cytochrome P450 1B1	1545	reviewed	Enzyme
Q16790	BXGT013670	Carbonic anhydrase 9	768	reviewed
Q6P2Q9	BXGT016446	Pre-mRNA-processing-splicing factor 8	10594	reviewed	Nucleic acid binding
Q7Z7C8	BXGT017261	Transcription initiation factor TFIID subunit 8	129685	reviewed
Q8N339	BXGT018503	Metallothionein-1M	4499	reviewed
Q8N6P7	BXGT018524	Interleukin-22 receptor subunit alpha-1	58985	reviewed	Receptor
Q8NHU6	BXGT018569	Tudor domain-containing protein 7	23424	reviewed	Enzyme
Q8TDS4	BXGT018812	Hydroxycarboxylic acid receptor 2	338442	reviewed
Q8TDS5	BXGT018813	Oxoeicosanoid receptor 1	165140	reviewed	G-protein coupled receptor
Q8TDV0	BXGT018815	Probable G-protein coupled receptor 151	134391	reviewed	G-protein coupled receptor
Q8WVQ1	BXGT018996	Soluble calcium-activated nucleotidase 1	124583	reviewed
Q8WWM9	BXGT019001	Cytoglobin	114757	reviewed
Q8WWY3	BXGT019006	U4/U6 small nuclear ribonucleoprotein Prp31	26121	reviewed	Nucleic acid binding
Q8WZA1	BXGT019024	Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1	55624	reviewed
Q92793	BXGT019374	CREB-binding protein	1387	reviewed
Q92834	BXGT019381	X-linked retinitis pigmentosa GTPase regulator	6103	reviewed
Q92934	BXGT019396	Bcl2-associated agonist of cell death	572	reviewed
Q92959	BXGT019400	Solute carrier organic anion transporter family member 2A1	6578	reviewed	Transporter
Q96AZ6	BXGT019621	Interferon-stimulated gene 20 kDa protein	3669	reviewed
Q96BZ9	BXGT019629	TBC1 domain family member 20	128637	reviewed
Q96EB6	BXGT019646	NAD-dependent protein deacetylase sirtuin-1	23411	reviewed	Epigenetic regulator
Q96FE5	BXGT019657	Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1	84894	reviewed	Receptor
Q96MG7	BXGT019696	Non-structural maintenance of chromosomes element 3 homolog	56160	reviewed	Cell adhesion
Q96NR8	BXGT019701	Retinol dehydrogenase 12	145226	reviewed	Enzyme
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q96PN6	BXGT019709	Adenylate cyclase type 10	55811	reviewed
Q99572	BXGT019935	P2X purinoceptor 7	5027	reviewed	Ion channel
Q99683	BXGT019947	Mitogen-activated protein kinase kinase kinase 5	4217	reviewed	Kinase
Q99685	BXGT019948	Monoglyceride lipase	11343	reviewed	Enzyme
Q99720	BXGT019955	Sigma non-opioid intracellular receptor 1	10280	reviewed
Q99972	BXGT019979	Myocilin	4653	reviewed	Cellular structure
Q9BXC0	BXGT020165	Hydroxycarboxylic acid receptor 1	27198	reviewed	G-protein coupled receptor
Q9BY41	BXGT020180	Histone deacetylase 8	55869	reviewed	Epigenetic regulator
Q9BYF1	BXGT020186	Angiotensin-converting enzyme 2	59272	reviewed	Enzyme
Q9BZS1	BXGT020203	Forkhead box protein P3	50943	reviewed
Q9GZX6	BXGT020428	Interleukin-22	50616	reviewed
Q9H0F7	BXGT020435	ADP-ribosylation factor-like protein 6	84100	reviewed
Q9H3M7	BXGT020462	Thioredoxin-interacting protein	10628	reviewed
Q9H492	BXGT020472	Microtubule-associated proteins 1A/1B light chain 3A	84557	reviewed	Cellular structure
Q9H4A3	BXGT020473	Serine/threonine-protein kinase WNK1	65125	reviewed	Kinase
Q9H6X2	BXGT020486	Anthrax toxin receptor 1	84168	reviewed	Receptor
Q9H8P0	BXGT020497	Polyprenol reductase	79644	reviewed
Q9HC29	BXGT020526	Nucleotide-binding oligomerization domain-containing protein 2	64127	reviewed	Enzyme
Q9HCG7	BXGT020533	Non-lysosomal glucosylceramidase	57704	reviewed
Q9NNW7	BXGT021139	Thioredoxin reductase 2, mitochondrial	10587	reviewed	Enzyme
Q9NP56	BXGT021142	cAMP-specific 3',5'-cyclic phosphodiesterase 7B	27115	reviewed
Q9NP58	BXGT021143	ATP-binding cassette sub-family B member 6, mitochondrial	10058	reviewed	Transporter
Q9NPG2	BXGT021155	Neuroglobin	58157	reviewed	Transporter
Q9NPI8	BXGT021161	Fanconi anemia group F protein	2188	reviewed
Q9NR71	BXGT021180	Neutral ceramidase	56624	reviewed
Q9NWB1	BXGT021231	RNA binding protein fox-1 homolog 1	54715	reviewed	Nucleic acid binding
Q9NX14	BXGT021242	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial	54539	reviewed	Enzyme
Q9P286	BXGT021299	Serine/threonine-protein kinase PAK 5	57144	reviewed	Kinase
Q9UBM7	BXGT021657	7-dehydrocholesterol reductase	1717	reviewed	Enzyme
Q9UBN7	BXGT021658	Histone deacetylase 6	10013	reviewed	Epigenetic regulator
Q9UHD2	BXGT021697	Serine/threonine-protein kinase TBK1	29110	reviewed	Kinase
Q9UHF0	BXGT021699	Tachykinin-3	6866	reviewed
Q9UIK4	BXGT021720	Death-associated protein kinase 2	23604	reviewed	Kinase
Q9ULV1	BXGT021764	Frizzled-4	8322	reviewed	G-protein coupled receptor
Q9UMX1	BXGT021778	Suppressor of fused homolog	51684	reviewed
Q9Y251	BXGT022215	Heparanase	10855	reviewed	Enzyme
Q9Y2J8	BXGT022237	Protein-arginine deiminase type-2	11240	reviewed
Q9Y2Q3	BXGT022242	Glutathione S-transferase kappa 1	373156	reviewed
Q9Y2R2	BXGT022243	Tyrosine-protein phosphatase non-receptor type 22	26191	reviewed
Q9Y2Z4	BXGT022251	Tyrosine--tRNA ligase, mitochondrial	51067	reviewed	Enzyme
Q9Y3S1	BXGT022266	Serine/threonine-protein kinase WNK2	65268	reviewed	Kinase
Q9Y5X4	BXGT022306	Photoreceptor-specific nuclear receptor	10002	reviewed	Nuclear receptor
Q9Y606	BXGT022312	tRNA pseudouridine synthase A	80324	reviewed	Enzyme
Q9Y6D6	BXGT022326	Brefeldin A-inhibited guanine nucleotide-exchange protein 1	10565	reviewed
Q9NYP7	BXGT022661	Elongation of very long chain fatty acids protein 5	60481	reviewed	Enzyme
Q96KN7	BXGT022801	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1	57096	reviewed	Enzyme modulator
P19235	BXGT022895	Erythropoietin receptor	2057	reviewed	Receptor
Q9GZQ8	BXGT023414	Microtubule-associated proteins 1A/1B light chain 3B	81631	reviewed	Cellular structure
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
Q99958	BXGT023732	Forkhead box protein C2	2303	reviewed	Transcription factor
Q9BQQ3	BXGT024065	Golgi reassembly-stacking protein 1	64689	reviewed
Q9H694	BXGT024116	Protein bicaudal C homolog 1	80114	reviewed	Transporter
O95140	BXGT024482	Mitofusin-2	9927	reviewed	Enzyme
Q9H9S5	BXGT024623	Fukutin-related protein	79147	reviewed
O43837	BXGT024635	Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial	3420	reviewed	Enzyme
O43583	BXGT024866	Density-regulated protein	8562	reviewed	Enzyme
Q13635	BXGT024910	Protein patched homolog 1	5727	reviewed
Q9UNE7	BXGT025000	E3 ubiquitin-protein ligase CHIP	10273	reviewed
Q9GZV5	BXGT025439	WW domain-containing transcription regulator protein 1	25937	reviewed	Enzyme modulator
Q9BYC5	BXGT025656	Alpha-(1,6)-fucosyltransferase	2530	reviewed
P35250	BXGT025854	Replication factor C subunit 2	5982	reviewed	Enzyme
Q86SQ9	BXGT025875	Dehydrodolichyl diphosphate synthase complex subunit DHDDS	79947	reviewed	Enzyme
Q9UQE7	BXGT025899	Structural maintenance of chromosomes protein 3	9126	reviewed
P43320	BXGT026151	Beta-crystallin B2	1415	reviewed
O43172	BXGT026158	U4/U6 small nuclear ribonucleoprotein Prp4	9128	reviewed	Nucleic acid binding
P02489	BXGT026168	Alpha-crystallin A chain	1409	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}