Showing entry for Mu-type opioid receptor


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT010343
Protein NameMu-type opioid receptor
Uniport IdP42866
GeneOprm1
Gene Id18390
Domain7tm_1
Pfam PF00001  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0002438 acute inflammatory response to antigenic stimulus
Biological Process GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway
Biological Process GO:0007197 adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway
Biological Process GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
Biological Process GO:0031635 adenylate cyclase-inhibiting opioid receptor signaling pathway
Biological Process GO:0048149 behavioral response to ethanol
Biological Process GO:0042755 eating behavior
Biological Process GO:0044849 estrous cycle
Biological Process GO:0060079 excitatory postsynaptic potential
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0007626 locomotory behavior
Biological Process GO:0106072 negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
Biological Process GO:0043951 negative regulation of cAMP-mediated signaling
Biological Process GO:0051481 negative regulation of cytosolic calcium ion concentration
Biological Process GO:0045019 negative regulation of nitric oxide biosynthetic process
Biological Process GO:0061358 negative regulation of Wnt protein secretion
Biological Process GO:0007218 neuropeptide signaling pathway
Biological Process GO:0038003 opioid receptor signaling pathway
Biological Process GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
Biological Process GO:0032100 positive regulation of appetite
Biological Process GO:0043950 positive regulation of cAMP-mediated signaling
Biological Process GO:0007204 positive regulation of cytosolic calcium ion concentration
Biological Process GO:0070374 positive regulation of ERK1 and ERK2 cascade
Biological Process GO:0050769 positive regulation of neurogenesis
Biological Process GO:0045429 positive regulation of nitric oxide biosynthetic process
Biological Process GO:0080135 regulation of cellular response to stress
Biological Process GO:2000310 regulation of NMDA receptor activity
Biological Process GO:0051930 regulation of sensory perception of pain
Biological Process GO:0042220 response to cocaine
Biological Process GO:0045471 response to ethanol
Biological Process GO:0032094 response to food
Biological Process GO:0070848 response to growth factor
Biological Process GO:0032496 response to lipopolysaccharide
Biological Process GO:0009314 response to radiation
Biological Process GO:0019233 sensory perception of pain
Biological Process GO:0042060 wound healing
molecular function GO:0004979 beta-endorphin receptor activity
molecular function GO:0031005 filamin binding
molecular function GO:0001965 G-protein alpha-subunit binding
molecular function GO:0031681 G-protein beta-subunit binding
molecular function GO:0004930 G protein-coupled receptor activity
molecular function GO:0038047 morphine receptor activity
molecular function GO:0042923 neuropeptide binding
molecular function GO:0004985 opioid receptor activity
molecular function GO:0042277 peptide binding
molecular function GO:0008022 protein C-terminus binding
molecular function GO:0019904 protein domain specific binding
molecular function GO:0005245 voltage-gated calcium channel activity
cellular component GO:0030424 axon
cellular component GO:0005737 cytoplasm
cellular component GO:0030425 dendrite
cellular component GO:0032839 dendrite cytoplasm
cellular component GO:0032590 dendrite membrane
cellular component GO:0005768 endosome
cellular component GO:0005925 focal adhesion
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0099055 integral component of postsynaptic membrane
cellular component GO:0099056 integral component of presynaptic membrane
cellular component GO:0016020 membrane
cellular component GO:0045121 membrane raft
cellular component GO:0043005 neuron projection
cellular component GO:0043204 perikaryon
cellular component GO:0005886 plasma membrane
cellular component GO:0042383 sarcolemma
cellular component GO:0097444 spine apparatus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000303 Eupatilin 344.32
BXGC0001733 Tangeritin 372.37
BXGC0002032 Gardenin B 358.34
BXGC0003948 8-Methoxycirsilineol 374.34
BXGC0005870 Codeine 299.36
BXGC0008980 Xanthomicrol 344.32
BXGC0009542 Sideritiflavone 360.31
BXGC0011725 (-)-Morphine 285.34
BXGC0014360 1-[(2E,4E,6E)-7-(2-Thienyl)-2,4,6-Heptatrienoyl]-2,3-Dehydropiperidine 271.1
BXGC0015160 1-[(2E,4E,6E)-7-(2-Thienyl)-2,4,6-Heptatrienoyl]Piperidine 273.12
BXGC0021509 (2E,4E,6E)-N-Isobutyl-7-(2-Thienyl)-2,4,6-Heptatrienamide 261.12
BXGC0024991 (2Z)-5-{[(2E,4E,6E)-7-(2-Thienyl)-2,4,6-Heptatrienoyl]Amino}-2-Pentenyl 3-Methylbutanoate 373.17
BXGC0026391 Naloxone 327.15
BXGC0027156 1-[(2E,4E)-Tetradecadienoyl]Piperidine 291.26
BXGC0028471 Monoolein 356.29
BXGC0030901 Morphine 285.14
BXGC0031352 9-Isovaleroxy Balanophonin 440.18
BXGC0032351 Nalorphine 311.15
BXGC0034587 Phenazocine 321.21
BXGC0036439 N-Isobutyl-(2E,4E)-Dodecadienamide 251.22
BXGC0038316 Cholesterol 386.35
BXGC0040285 (2E,4E,6E)-N-Isopentyl-7-(2-Thienyl)-2,4,6-Heptatrienamide 275.13
BXGC0040732 Tetradeca-2E,4E,8Z-Trienoic Acid Isobutylamide 277.24
BXGC0041045 Buprenorphine 467.3
BXGC0041129 Tetradeca-2E,4E-Dienoic Acid Isobutylamide 279.26
BXGC0043965 1-[(2E,4E,8Z)-Tetradecatrienoyl]Piperidine 289.24
BXGC0049170 Oxycodone 315.15
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein