Showing entry for Naloxone


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0026391
Compound NameNaloxone
Structure
FormulaC19H21NO4
InchiKeyUZHSEJADLWPNLE-GRGSLBFTSA-N
SMILESC=CCN1CC[C@@]23[C@@]4([C@H]1Cc1c3c(O[C@H]2C(=O)CC4)c(cc1)O)O
InchiInChI=1S/C19H21NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,14,17,21,23H,1,5-10H2/t14-,17+,18+,19-/m1/s1
IUPAC(4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one
Molecular Weight327.15
Pubchem Id5284596
Chembl IdCHEMBL80
Targets of Information Source
DrugBank DB01183
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 approved; vet_approved antagonist
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 approved; vet_approved antagonist
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 approved; vet_approved antagonist
P16220 BXGT008206 Cyclic AMP-responsive element-binding protein 1 reviewed - CREB1 approved; vet_approved other/unknown
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 approved; vet_approved antagonist,other/unknown
O00206 BXGT003894 Toll-like receptor 4 reviewed - TLR4 approved; vet_approved inhibitor
P23141 BXGT008830 Liver carboxylesterase 1 reviewed Enzyme CES1 approved; vet_approved -
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB 54795
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 - 616 - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 - 182 - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 - 704 - -
reviewed BXGT009621 5-hydroxytryptamine receptor 7 reviewed Htr7 >10000 - - -
reviewed BXGT019575 D(1A) dopamine receptor reviewed DRD1 >10000 - - -
reviewed BXGT009780 Kappa-type opioid receptor reviewed Oprk1 16 - - -
reviewed BXGT009780 Kappa-type opioid receptor reviewed Oprk1 0.5 - - -
reviewed BXGT021402 Sigma non-opioid intracellular receptor 1 reviewed Sigmar1 3500 - - -
reviewed BXGT021402 Sigma non-opioid intracellular receptor 1 reviewed Sigmar1 >10000 - - -
reviewed BXGT009618 Delta-type opioid receptor reviewed Oprd1 26 - - -
reviewed BXGT019577 Beta-arrestin-1 reviewed ARRB1 67.4 - - -
reviewed BXGT011860 Delta-type opioid receptor (Fragment) reviewed OPRD1 13.5 - - -
reviewed BXGT011862 Mu-type opioid receptor reviewed OPRM1 3.3 - - -
reviewed BXGT011862 Mu-type opioid receptor reviewed OPRM1 8.1 - - -
reviewed BXGT012199 Mu-type opioid receptor (Fragment) reviewed OPRM1 2.34 - - -
reviewed BXGT009565 Sodium-dependent serotonin transporter reviewed Slc6a4 >10000 - - -
reviewed BXGT009729 Delta-type opioid receptor reviewed Oprd1 >10000 - - -
reviewed BXGT009729 Delta-type opioid receptor reviewed Oprd1 36.5 - - -
reviewed BXGT009780 Kappa-type opioid receptor reviewed Oprk1 8950 - - -
reviewed BXGT009780 Kappa-type opioid receptor reviewed Oprk1 4.91 - - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 3550 - - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 0.559 - - -
reviewed BXGT026178 Neuropeptides B/W receptor type 1 reviewed G-protein coupled receptor NPBWR1 3000 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 1000 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 1.4 - - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 1000 - - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 141.3 - - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 1000 - - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 13.8 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 1.35 - - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 17 - - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 2.3 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 0.93 - - -
reviewed BXGT011367 D(2) dopamine receptor reviewed Drd2 >10000 - - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 67.5 - - -
reviewed BXGT011860 Delta-type opioid receptor (Fragment) reviewed OPRD1 19.8 - - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 2.5 - - -
reviewed BXGT010224 Kappa-type opioid receptor reviewed OPRK1 3.8 - - -
reviewed BXGT012199 Mu-type opioid receptor (Fragment) reviewed OPRM1 1.5 - - -
reviewed BXGT010343 Mu-type opioid receptor reviewed Oprm1 0.31 - - -
reviewed BXGT010343 Mu-type opioid receptor reviewed Oprm1 0.67 - - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 0.9 - - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 41 - - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 33 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 - 7.3 - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 1.1 - - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - - 154 -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - - 5 -
reviewed BXGT012199 Mu-type opioid receptor (Fragment) reviewed OPRM1 - 8.9 - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 - 62 - -
reviewed BXGT010224 Kappa-type opioid receptor reviewed OPRK1 - 50 - -
reviewed BXGT010224 Kappa-type opioid receptor reviewed OPRK1 - - 20 -
reviewed BXGT010224 Kappa-type opioid receptor reviewed OPRK1 66 - - -
reviewed BXGT012199 Mu-type opioid receptor (Fragment) reviewed OPRM1 - - 3.2 -
reviewed BXGT009618 Delta-type opioid receptor reviewed Oprd1 - - 50 -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 19 - - -
reviewed BXGT010224 Kappa-type opioid receptor reviewed OPRK1 12 - - -
reviewed BXGT019955 Sigma non-opioid intracellular receptor 1 reviewed SIGMAR1 >100000 - - -
reviewed BXGT012199 Mu-type opioid receptor (Fragment) reviewed OPRM1 1.1 - - -
reviewed BXGT019955 Sigma non-opioid intracellular receptor 1 reviewed SIGMAR1 - >100000 - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 3.7 - - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 - 138 - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 6.3 - - -
reviewed BXGT009729 Delta-type opioid receptor reviewed Oprd1 32 - - -
reviewed BXGT010224 Kappa-type opioid receptor reviewed OPRK1 6.9 - - -
reviewed BXGT010879 C-C chemokine receptor type 5 reviewed Ccr5 - - 21 -
reviewed BXGT010879 C-C chemokine receptor type 5 reviewed Ccr5 - - 11 -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 43 - - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 1.2 - - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 1.4 - - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 51 - - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 38 - - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 - 151 - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 - 50 - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 11 - - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 37 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 3.7 - - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 76 - - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 1.1 - - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 - 320 - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 - 23 - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 120 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 4.2 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 0.57 - - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 21 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 354 - - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 1516 - - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 362 - - -
reviewed BXGT010224 Kappa-type opioid receptor reviewed OPRK1 7.3 - - -
reviewed BXGT010224 Kappa-type opioid receptor reviewed OPRK1 15 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 2.3 - - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 103 - - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 2 - - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 30 - - -
reviewed BXGT010867 Cytochrome P450 2J2 reviewed CYP2J2 - >50000 - -
reviewed BXGT012199 Mu-type opioid receptor (Fragment) reviewed OPRM1 2.1 - - -
reviewed BXGT009729 Delta-type opioid receptor reviewed Oprd1 2.5 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 1.1 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 1.3 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 1.6 - - -
reviewed BXGT009436 Adenosine receptor A1 reviewed G-protein coupled receptor ADORA1 >50000 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 1.5 - - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 3 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 0.98 - - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - 44 - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - 150 - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - 12 - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - 1.4 - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - 0.009 - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - 0.004 - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - 3.2 - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - 3 - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - - 0.4 -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - 2 - -
reviewed BXGT009730 Kappa-type opioid receptor reviewed Oprk1 - 500000 - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 0.25 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 0.23 - - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 - 43 - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - - 3 -
reviewed BXGT009780 Kappa-type opioid receptor reviewed Oprk1 - - 4.5 -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 9.2 - - -
reviewed BXGT009780 Kappa-type opioid receptor reviewed Oprk1 - - 1 -
reviewed BXGT009729 Delta-type opioid receptor reviewed Oprd1 - - 18 -
reviewed BXGT011862 Mu-type opioid receptor reviewed OPRM1 - 5 - -
reviewed BXGT008448 D(3) dopamine receptor reviewed Drd3 >20000 - - -
reviewed BXGT010224 Kappa-type opioid receptor reviewed OPRK1 3.2 - - -
reviewed BXGT012199 Mu-type opioid receptor (Fragment) reviewed OPRM1 0.68 - - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 - 1.5 - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 - 2 - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 3.6 - - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 - - - 6.6
reviewed BXGT007506 Adenosine receptor A3 reviewed G-protein coupled receptor ADORA3 - 1.6 - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 - - - 10
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 0.79 - - -
reviewed BXGT010224 Kappa-type opioid receptor reviewed OPRK1 3.17 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 0.66 - - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 15 - - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 4.5 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 0.562341 - - -
CHEMBL CHEMBL80
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 IC50 '=' 7 nM
O70528 BXGT005068 5-hydroxytryptamine receptor 4 reviewed - HTR4 Ki - - -
P21452 BXGT008653 Substance-K receptor reviewed G-protein coupled receptor TACR2 Ki - - -
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 IC50 '=' 3 -
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 IC50 '=' 3 -
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 IC50 '=' 3 -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ki '=' 1 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 IC50 '=' 1 nM
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 IC50 '=' 1 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 IC50 '=' 1 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Emax '=' 25 %
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 Ki '=' 32 nM
P32300 BXGT009618 Delta-type opioid receptor reviewed - Oprd1 Ke '=' 40 nM
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 Ki '=' 6 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki '=' 2 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Ki '=' 3 nM
P42866 BXGT010343 Mu-type opioid receptor reviewed - Oprm1 AD50 '=' 0 mg kg-1
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Selectivity ratio '=' 12 -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Selectivity ratio '=' 12 -
P33534 BXGT009730 Kappa-type opioid receptor reviewed - Oprk1 Control '=' 108 %
P32300 BXGT009618 Delta-type opioid receptor reviewed - Oprd1 Control '=' 108 %
P42866 BXGT010343 Mu-type opioid receptor reviewed - Oprm1 Control '=' 108 %
P32300 BXGT009618 Delta-type opioid receptor reviewed - Oprd1 Ke '=' 9 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Control '=' 89 %
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Control '=' 89 %
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Control '=' 89 %
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 EC50 '=' 1 nM
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 EC50 '=' 1 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 EC50 '=' 1 nM
P33534 BXGT009730 Kappa-type opioid receptor reviewed - Oprk1 Ke '=' 15 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki '=' 0 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki '=' 41 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 IC50 '=' 2 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki '=' 42 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Activity '=' 80 %
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki '=' 0 nM
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 IC50 - - -
P41597 BXGT010268 C-C chemokine receptor type 2 reviewed - CCR2 Ki - - -
P32238 BXGT009611 Cholecystokinin receptor type A reviewed G-protein coupled receptor CCKAR Ki - - -
P23219 BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 IC50 - - -
Q16539 BXGT013634 Mitogen-activated protein kinase 14 reviewed Kinase MAPK14 IC50 - - -
P14416 BXGT008011 D(2) dopamine receptor reviewed G-protein coupled receptor DRD2 Ki - - -
P20781 BXGT008598 Glycine receptor subunit beta reviewed - Glrb IC50 - - -
P07727 BXGT006662 Glycine receptor subunit alpha-1 reviewed - Glra1 IC50 - - -
P24524 BXGT008974 Glycine receptor subunit alpha-3 reviewed - Glra3 IC50 - - -
P22771 BXGT008806 Glycine receptor subunit alpha-2 reviewed - Glra2 IC50 - - -
P29477 BXGT009355 Nitric oxide synthase, inducible reviewed - Nos2 IC50 - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki '=' 1 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki '=' 0 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ke '=' 2 nM
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 Ki - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Activity '=' 50 %
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki '=' 21 nM
P15823 BXGT008160 Alpha-1B adrenergic receptor reviewed - Adra1b IC50 - - -
P08913 BXGT006841 Alpha-2A adrenergic receptor reviewed G-protein coupled receptor ADRA2A Ki - - -
P00918 BXGT005690 Carbonic anhydrase 2 reviewed - CA2 Ki - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki '=' 4 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki '=' 1 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Activity - - -
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Ki '=' 6 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki '=' 19 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 IC50 '=' 49 nM
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 AD50 '=' 3 mg kg-1
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki '=' 0 nM
P21554 BXGT008662 Cannabinoid receptor 1 reviewed G-protein coupled receptor CNR1 IC50 - - -
P51682 BXGT010879 C-C chemokine receptor type 5 reviewed - Ccr5 Kd '=' 20 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki '=' 38 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Activity - - -
P0DMS8 BXGT007506 Adenosine receptor A3 reviewed G-protein coupled receptor ADORA3 IC50 - - -
P18089 BXGT008379 Alpha-2B adrenergic receptor reviewed G-protein coupled receptor ADRA2B Ki - - -
P18825 BXGT008426 Alpha-2C adrenergic receptor reviewed G-protein coupled receptor ADRA2C Ki - - -
P30988 BXGT009491 Calcitonin receptor reviewed G-protein coupled receptor CALCR IC50 - - -
P21554 BXGT008662 Cannabinoid receptor 1 reviewed G-protein coupled receptor CNR1 Ki - - -
P41597 BXGT010268 C-C chemokine receptor type 2 reviewed - CCR2 IC50 - - -
P25024 BXGT009005 C-X-C chemokine receptor type 1 reviewed G-protein coupled receptor CXCR1 IC50 - - -
P46721 BXGT010536 Solute carrier organic anion transporter family member 1A2 reviewed Transporter SLCO1A2 Activity - - -
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 Kd '=' 1 nM
P08575 BXGT006793 Receptor-type tyrosine-protein phosphatase C reviewed Enzyme PTPRC IC50 - - -
Q9R0C9 BXGT021402 Sigma non-opioid intracellular receptor 1 reviewed - Sigmar1 Ki '>' 10000 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki '=' 37 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 IC50 '=' 0 nM
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 IC50 '=' 0 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 IC50 '=' 0 nM
P25025 BXGT009006 C-X-C chemokine receptor type 2 reviewed G-protein coupled receptor CXCR2 IC50 - - -
P18089 BXGT008379 Alpha-2B adrenergic receptor reviewed G-protein coupled receptor ADRA2B IC50 - - -
P08588 BXGT006795 Beta-1 adrenergic receptor reviewed G-protein coupled receptor ADRB1 Ki - - -
P07943 BXGT006700 Aldo-keto reductase family 1 member B1 reviewed - Akr1b1 Ki - - -
A6XA80 BXGT001522 Leukotriene C4 synthase reviewed - LTC4S IC50 - - -
P32245 BXGT009614 Melanocortin receptor 4 reviewed G-protein coupled receptor MC4R Ki - - -
P12822 BXGT007850 Angiotensin-converting enzyme reviewed - ACE Ki - - -
P27361 BXGT009176 Mitogen-activated protein kinase 3 reviewed Kinase MAPK3 Ki - - -
P11509 BXGT007716 Cytochrome P450 2A6 reviewed - CYP2A6 IC50 - - -
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 IC50 - - -
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 Ki - - -
P25100 BXGT009017 Alpha-1D adrenergic receptor reviewed G-protein coupled receptor ADRA1D IC50 - - -
Q99720 BXGT019955 Sigma non-opioid intracellular receptor 1 reviewed - SIGMAR1 IC50 '>' 100000 nM
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 Ki '=' 0 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 IC50 '=' 75 nM
P35462 BXGT009835 D(3) dopamine receptor reviewed G-protein coupled receptor DRD3 Ki - - -
P21917 BXGT008707 D(4) dopamine receptor reviewed G-protein coupled receptor DRD4 Ki - - -
P35367 BXGT009821 Histamine H1 receptor reviewed G-protein coupled receptor HRH1 IC50 - - -
P25021 BXGT009004 Histamine H2 receptor reviewed G-protein coupled receptor HRH2 Ki - - -
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 IC50 - - -
P08173 BXGT006738 Muscarinic acetylcholine receptor M4 reviewed G-protein coupled receptor CHRM4 Ki - - -
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 Ki '=' 66 nM
Q12809 BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 Ki - - -
Q690N0 BXGT016199 Progesterone receptor unreviewed - PGR IC50 - - -
Q60492 BXGT015986 Sigma non-opioid intracellular receptor 1 reviewed - SIGMAR1 Ki - - -
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Kd '=' 154 nM
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 Kd '=' 154 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 Kd '=' 154 nM
P30542 BXGT009436 Adenosine receptor A1 reviewed G-protein coupled receptor ADORA1 Ki - - -
P29274 BXGT009327 Adenosine receptor A2a reviewed G-protein coupled receptor ADORA2A Ki - - -
P0DMS8 BXGT007506 Adenosine receptor A3 reviewed G-protein coupled receptor ADORA3 Ki - - -
P51681 BXGT010878 C-C chemokine receptor type 5 reviewed G-protein coupled receptor CCR5 Ki - - -
P28482 BXGT009263 Mitogen-activated protein kinase 1 reviewed Kinase MAPK1 IC50 - - -
P28482 BXGT009263 Mitogen-activated protein kinase 1 reviewed Kinase MAPK1 Ki - - -
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Ki '=' 1 nM
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 Ki '=' 7 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki '=' 2 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 ED50 '=' 0 umol.kg-1
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 ED50 '=' 0 umol.kg-1
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 ED50 '=' 0 umol.kg-1
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 IC50 '=' 138 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Emax '=' 13 %
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki '=' 3 nM
P42866 BXGT010343 Mu-type opioid receptor reviewed - Oprm1 Kd '=' 10 nM
P33534 BXGT009730 Kappa-type opioid receptor reviewed - Oprk1 Kd '=' 125 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 % recovery '=' 100 -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 % recovery '=' 100 -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 % recovery '=' 100 -
P16662 BXGT008253 UDP-glucuronosyltransferase 2B7 reviewed - UGT2B7 Activity '=' 2908 pm/min/mg
P16662 BXGT008253 UDP-glucuronosyltransferase 2B7 reviewed - UGT2B7 Activity '=' 3400 pm/min/mg
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ki '=' 9 nM
P30542 BXGT009436 Adenosine receptor A1 reviewed G-protein coupled receptor ADORA1 Ki '>' 50000 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Recovery '=' 0 %
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Recovery '=' 0 %
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Recovery '=' 0 %
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 Ke '=' 1 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 IC50 '=' 23 nM
P06239 BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK Ki - - -
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 IC50 '=' 12 nM
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 IC50 '=' 12 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 IC50 '=' 12 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Activity '=' 0 %
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 Activity '=' 23 %
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 IC50 '=' 2 nM
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 IC50 '=' 2 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 IC50 '=' 2 nM
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 Ke '=' 16 nM
P33534 BXGT009730 Kappa-type opioid receptor reviewed - Oprk1 Control '=' 25 %
P32300 BXGT009618 Delta-type opioid receptor reviewed - Oprd1 Control '=' 25 %
P42866 BXGT010343 Mu-type opioid receptor reviewed - Oprm1 Control '=' 25 %
Q9HAW9 BXGT020510 UDP-glucuronosyltransferase 1-8 reviewed - UGT1A8 Vmax '=' 121 pmol/min/mg protein
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Control '=' 111 %
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 EC50 '=' 6 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki ratio - - -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki ratio - - -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ki ratio - - -
P27361 BXGT009176 Mitogen-activated protein kinase 3 reviewed Kinase MAPK3 IC50 - - -
P35354 BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 IC50 - - -
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 IC50 '=' 2000 nM
P21728 BXGT008686 D(1A) dopamine receptor reviewed G-protein coupled receptor DRD1 Ki - - -
P25101 BXGT009018 Endothelin-1 receptor reviewed G-protein coupled receptor EDNRA IC50 - - -
Q92731 BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 IC50 - - -
P04035 BXGT006129 3-hydroxy-3-methylglutaryl-coenzyme A reductase reviewed - HMGCR Ki - - -
Q9Y271 BXGT022222 Cysteinyl leukotriene receptor 1 reviewed G-protein coupled receptor CYSLTR1 Ki - - -
P12530 BXGT007827 Arachidonate 15-lipoxygenase reviewed - ALOX15 Ki - - -
P33032 BXGT009689 Melanocortin receptor 5 reviewed G-protein coupled receptor MC5R Ki - - -
P08173 BXGT006738 Muscarinic acetylcholine receptor M4 reviewed G-protein coupled receptor CHRM4 IC50 - - -
P25929 BXGT009078 Neuropeptide Y receptor type 1 reviewed G-protein coupled receptor NPY1R Ki - - -
P49146 BXGT010681 Neuropeptide Y receptor type 2 reviewed G-protein coupled receptor NPY2R IC50 - - -
P49146 BXGT010681 Neuropeptide Y receptor type 2 reviewed G-protein coupled receptor NPY2R Ki - - -
P50052 BXGT010768 Type-2 angiotensin II receptor reviewed G-protein coupled receptor AGTR2 Ki - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 IC50 '=' 20 nM
P25024 BXGT009005 C-X-C chemokine receptor type 1 reviewed G-protein coupled receptor CXCR1 Ki - - -
P08311 BXGT006762 Cathepsin G reviewed Enzyme CTSG Ki - - -
P32300 BXGT009618 Delta-type opioid receptor reviewed - Oprd1 Kd '=' 44 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Kd '=' 0 nM
P22303 BXGT008751 Acetylcholinesterase reviewed Enzyme ACHE Ki - - -
P30411 BXGT009424 B2 bradykinin receptor reviewed G-protein coupled receptor BDKRB2 IC50 - - -
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 KT '=' 19 -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 % recovery '=' 100 -
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 Ki '=' 3 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Emax - - -
P07550 BXGT006636 Beta-2 adrenergic receptor reviewed G-protein coupled receptor ADRB2 Ki - - -
P13945 BXGT007972 Beta-3 adrenergic receptor reviewed G-protein coupled receptor ADRB3 IC50 - - -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 pKb '=' 7 -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Activity '=' 106 %
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 IC50 '=' 320 nM
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 Kd '=' 1 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 IC50 '=' 9 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 IC50 '=' 9 nM
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 Kd '=' 3 nM
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 IC50 '=' 8 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 IC50 '=' 62 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki '=' 33 nM
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 Ke '=' 2 nM
Q92731 BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 Ki - - -
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 IC50 - - -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 IC50 '=' 1461 nM
P06241 BXGT006429 Tyrosine-protein kinase Fyn reviewed Kinase FYN IC50 - - -
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 reviewed Kinase ERBB2 IC50 - - -
P06239 BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK IC50 - - -
P28564 BXGT009272 5-hydroxytryptamine receptor 1B reviewed - Htr1b Ki - - -
P23219 BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 Ki - - -
Q01959 BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 IC50 - - -
A6XA80 BXGT001522 Leukotriene C4 synthase reviewed - LTC4S Ki - - -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki '=' 515 nM
P29476 BXGT009354 Nitric oxide synthase, brain reviewed - Nos1 Ki - - -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Inhibition '=' 103 %
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Selectivity ratio '=' 7 -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Selectivity ratio '=' 7 -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 IC50 '=' 127 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 IC50 '=' 127 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ke '=' 10 nM
Q64133 BXGT016109 Amine oxidase [flavin-containing] A reviewed - Maoa Activity - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ratio '=' 1 -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ratio '=' 1 -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ratio '=' 1 -
P22310 BXGT008754 UDP-glucuronosyltransferase 1-4 reviewed - UGT1A4 Activity '=' 0 pm/min/mg
P22303 BXGT008751 Acetylcholinesterase reviewed Enzyme ACHE IC50 - - -
P43140 BXGT010360 Alpha-1A adrenergic receptor reviewed - Adra1a Ki - - -
P15823 BXGT008160 Alpha-1B adrenergic receptor reviewed - Adra1b Ki - - -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 IC50 '=' 1 nM
P33534 BXGT009730 Kappa-type opioid receptor reviewed - Oprk1 IC50 '=' 500000 nM
P32300 BXGT009618 Delta-type opioid receptor reviewed - Oprd1 IC50 '=' 500000 nM
P42866 BXGT010343 Mu-type opioid receptor reviewed - Oprm1 IC50 '=' 500000 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 EC50 - - -
O15439 BXGT004169 Multidrug resistance-associated protein 4 reviewed Transporter ABCC4 IC50 '=' 133000 nM
O95342 BXGT005373 Bile salt export pump reviewed Transporter ABCB11 IC50 '=' 133000 nM
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 IC50 '=' 50 nM
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 Ki '=' 2 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ki '=' 4 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 IC50 '=' 43 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 IC50 '=' 43 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 IC50 '=' 43 nM
P12530 BXGT007827 Arachidonate 15-lipoxygenase reviewed - ALOX15 IC50 - - -
P25105 BXGT009021 Platelet-activating factor receptor reviewed G-protein coupled receptor PTAFR IC50 - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Control '=' 98 %
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Control '=' 98 %
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Control '=' 98 %
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 IC50 '=' 151 nM
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 Kd '=' 4 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Imax '=' 55 %
Q99720 BXGT019955 Sigma non-opioid intracellular receptor 1 reviewed - SIGMAR1 Ki '>' 100000 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ke '=' 1 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ke '=' 1 nM
Q08209 BXGT012968 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform reviewed - PPP3CA Ki - - -
P50406 BXGT010796 5-hydroxytryptamine receptor 6 reviewed G-protein coupled receptor HTR6 Ki - - -
P21452 BXGT008653 Substance-K receptor reviewed G-protein coupled receptor TACR2 IC50 - - -
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 reviewed Kinase FLT1 IC50 - - -
P24557 BXGT008976 Thromboxane-A synthase reviewed - TBXAS1 IC50 - - -
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 reviewed Kinase FLT1 Ki - - -
P33534 BXGT009730 Kappa-type opioid receptor reviewed - Oprk1 AD50 '=' 1 mg kg-1
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 IC50 '=' 150 nM
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 IC50 '=' 150 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 IC50 '=' 150 nM
P19020 BXGT008448 D(3) dopamine receptor reviewed - Drd3 Ki '>' 20000 nM
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 Ke '=' 1 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Ki '=' 2 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki '=' 51 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Activity '=' 101 %
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 % recovery '=' 100 -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Activity '=' 51 -
Q06278 BXGT012869 Aldehyde oxidase reviewed Enzyme AOX1 Fm - - -
O95342 BXGT005373 Bile salt export pump reviewed Transporter ABCB11 IC50 '>' 135000 nM
O70528 BXGT005068 5-hydroxytryptamine receptor 4 reviewed - HTR4 IC50 - - -
P15207 BXGT008096 Androgen receptor reviewed - Ar IC50 - - -
P32241 BXGT009613 Vasoactive intestinal polypeptide receptor 1 reviewed G-protein coupled receptor VIPR1 Ki - - -
Q9HAW9 BXGT020510 UDP-glucuronosyltransferase 1-8 reviewed - UGT1A8 Km '=' 450000 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ke '=' 11 nM
P32300 BXGT009618 Delta-type opioid receptor reviewed - Oprd1 Activity '=' 101 %
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 IC50 '=' 44 nM
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 IC50 '=' 44 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 IC50 '=' 44 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Inhibition - - -
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Kd '=' 1 nM
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 Kd '=' 1 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 Kd '=' 1 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Selectivity '=' 0 -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Selectivity '=' 0 -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Max stimulation '=' 30 %
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Inhibition '=' 81 %
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 pKb '=' 7 -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Max inhibition '=' 98 %
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ki '=' 3 nM
P13945 BXGT007972 Beta-3 adrenergic receptor reviewed G-protein coupled receptor ADRB3 Ki - - -
P41595 BXGT010267 5-hydroxytryptamine receptor 2B reviewed G-protein coupled receptor HTR2B IC50 - - -
P37288 BXGT009977 Vasopressin V1a receptor reviewed G-protein coupled receptor AVPR1A Ki - - -
P41968 BXGT010275 Melanocortin receptor 3 reviewed G-protein coupled receptor MC3R IC50 - - -
P08246 BXGT006756 Neutrophil elastase reviewed Enzyme ELANE Ki - - -
P25021 BXGT009004 Histamine H2 receptor reviewed G-protein coupled receptor HRH2 IC50 - - -
P33032 BXGT009689 Melanocortin receptor 5 reviewed G-protein coupled receptor MC5R IC50 - - -
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 Ki - - -
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 IC50 - - -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ki '=' 30 nM
Q99720 BXGT019955 Sigma non-opioid intracellular receptor 1 reviewed - SIGMAR1 Ki - - -
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 IC50 - - -
P05181 BXGT006337 Cytochrome P450 2E1 reviewed - CYP2E1 IC50 - - -
P35462 BXGT009835 D(3) dopamine receptor reviewed G-protein coupled receptor DRD3 IC50 - - -
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 IC50 - - -
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 Ki - - -
P35354 BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 Ki - - -
P34972 BXGT009779 Cannabinoid receptor 2 reviewed G-protein coupled receptor CNR2 Inhibition - - -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ki '=' 10 nM
O95342 BXGT005373 Bile salt export pump reviewed Transporter ABCB11 IC50 '=' 549000 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Activity '=' 90 %
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 Ki '=' 3 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Inhibition '=' 50 %
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ratio Ki '=' 69 -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ratio Ki '=' 69 -
P42866 BXGT010343 Mu-type opioid receptor reviewed - Oprm1 Ke '=' 1 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Ki '=' 1 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Activity '=' 103 %
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 Ki - - -
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Kd '=' 0 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Kd '=' 5 nM
P32238 BXGT009611 Cholecystokinin receptor type A reviewed G-protein coupled receptor CCKAR IC50 - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki '=' 3 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Control '=' 105 %
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ki '=' 1 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki '=' 0 nM
P30542 BXGT009436 Adenosine receptor A1 reviewed G-protein coupled receptor ADORA1 IC50 - - -
P43140 BXGT010360 Alpha-1A adrenergic receptor reviewed - Adra1a IC50 - - -
P08588 BXGT006795 Beta-1 adrenergic receptor reviewed G-protein coupled receptor ADRB1 IC50 - - -
P07550 BXGT006636 Beta-2 adrenergic receptor reviewed G-protein coupled receptor ADRB2 IC50 - - -
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 IC50 '=' 0 nM
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 IC50 '=' 0 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 IC50 '=' 0 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Ratio '=' 2 -
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 Ratio '=' 2 -
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 Ratio '=' 2 -
P32300 BXGT009618 Delta-type opioid receptor reviewed - Oprd1 Kd '=' 50 nM
P33534 BXGT009730 Kappa-type opioid receptor reviewed - Oprk1 Control '=' 15 %
P32300 BXGT009618 Delta-type opioid receptor reviewed - Oprd1 Control '=' 15 %
P42866 BXGT010343 Mu-type opioid receptor reviewed - Oprm1 Control '=' 15 %
P33534 BXGT009730 Kappa-type opioid receptor reviewed - Oprk1 Control '=' 105 %
P32300 BXGT009618 Delta-type opioid receptor reviewed - Oprd1 Control '=' 105 %
P42866 BXGT010343 Mu-type opioid receptor reviewed - Oprm1 Control '=' 105 %
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 % recovery '=' 0 -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 % recovery '=' 0 -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 % recovery '=' 0 -
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 % recovery '=' 0 -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 % recovery '=' 0 -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Recovery '=' 100 %
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Recovery '=' 100 %
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Recovery '=' 100 %
P79350 BXGT011862 Mu-type opioid receptor reviewed - OPRM1 IC50 '=' 5 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ki '=' 14 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki '=' 1 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Kp '=' 980000000 -
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 ln Kp '=' 20 -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ratio Ki '=' 1 -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ratio Ki '=' 1 -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki '=' 76 nM
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 Ki - - -
P21728 BXGT008686 D(1A) dopamine receptor reviewed G-protein coupled receptor DRD1 IC50 - - -
P04035 BXGT006129 3-hydroxy-3-methylglutaryl-coenzyme A reductase reviewed - HMGCR IC50 - - -
P15127 BXGT008085 Insulin receptor reviewed - Insr IC50 - - -
P25929 BXGT009078 Neuropeptide Y receptor type 1 reviewed G-protein coupled receptor NPY1R IC50 - - -
Q12809 BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 IC50 - - -
P29466 BXGT009349 Caspase-1 reviewed Enzyme CASP1 Ki - - -
P08246 BXGT006756 Neutrophil elastase reviewed Enzyme ELANE IC50 - - -
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 Ki '=' 1 nM
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 Ki '=' 12 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 IC50 '=' 1 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 IC50 '=' 1 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 IC50 '=' 1 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Control '=' 0 %
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Control '=' 0 %
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Control '=' 0 %
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Kd '=' 3 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki '=' 120 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Kp '=' 20 -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ki '=' 0 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Activity '=' 62 -
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Ratio '=' 1 -
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 Ratio '=' 1 -
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 Ratio '=' 1 -
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 IC50 '=' 3 -
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 IC50 '=' 3 -
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 IC50 '=' 3 -
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 Kd '=' 18 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 EC50 '=' 10 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Selectivity '=' 0 -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Selectivity '=' 0 -
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 Kd '=' 19 nM
P51682 BXGT010879 C-C chemokine receptor type 5 reviewed - Ccr5 Kd '=' 10 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki '=' 1 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Control '=' 72 %
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Control '=' 72 %
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Control '=' 72 %
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Kt '=' 260000000 -
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 Ki '=' 2 nM
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 Ki '=' 2 nM
P25105 BXGT009021 Platelet-activating factor receptor reviewed G-protein coupled receptor PTAFR Ki - - -
Q690N0 BXGT016199 Progesterone receptor unreviewed - PGR Ki - - -
P12822 BXGT007850 Angiotensin-converting enzyme reviewed - ACE IC50 - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Imax '=' 92 %
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 Ki - - -
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 IC50 - - -
P14416 BXGT008011 D(2) dopamine receptor reviewed G-protein coupled receptor DRD2 IC50 - - -
P25101 BXGT009018 Endothelin-1 receptor reviewed G-protein coupled receptor EDNRA Ki - - -
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 reviewed Kinase ERBB2 Ki - - -
P28223 BXGT009239 5-hydroxytryptamine receptor 2A reviewed G-protein coupled receptor HTR2A Ki - - -
P28335 BXGT009255 5-hydroxytryptamine receptor 2C reviewed G-protein coupled receptor HTR2C Ki - - -
Q99720 BXGT019955 Sigma non-opioid intracellular receptor 1 reviewed - SIGMAR1 IC50 - - -
P15207 BXGT008096 Androgen receptor reviewed - Ar Ki - - -
P32245 BXGT009614 Melanocortin receptor 4 reviewed G-protein coupled receptor MC4R IC50 - - -
P21397 BXGT008644 Amine oxidase [flavin-containing] A reviewed - MAOA Ki - - -
P08311 BXGT006762 Cathepsin G reviewed Enzyme CTSG IC50 - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Activity '=' 97 %
Q9HAW8 BXGT020509 UDP-glucuronosyltransferase 1-10 reviewed - UGT1A10 Activity '=' 0 pm/min/mg
P35503 BXGT009840 UDP-glucuronosyltransferase 1-3 reviewed - UGT1A3 Activity '=' 14 pm/min/mg
P16662 BXGT008253 UDP-glucuronosyltransferase 2B7 reviewed - UGT2B7 Activity '=' 3462 pm/min/mg
P16662 BXGT008253 UDP-glucuronosyltransferase 2B7 reviewed - UGT2B7 Activity '=' 131 pm/min/mg
P17252 BXGT008294 Protein kinase C alpha type reviewed Kinase PRKCA Ki - - -
P28223 BXGT009239 5-hydroxytryptamine receptor 2A reviewed G-protein coupled receptor HTR2A IC50 - - -
P41595 BXGT010267 5-hydroxytryptamine receptor 2B reviewed G-protein coupled receptor HTR2B Ki - - -
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 Ki - - -
P50052 BXGT010768 Type-2 angiotensin II receptor reviewed G-protein coupled receptor AGTR2 IC50 - - -
P00918 BXGT005690 Carbonic anhydrase 2 reviewed - CA2 IC50 - - -
P51679 BXGT010877 C-C chemokine receptor type 4 reviewed G-protein coupled receptor CCR4 Ki - - -
P51681 BXGT010878 C-C chemokine receptor type 5 reviewed G-protein coupled receptor CCR5 IC50 - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki '=' 8 nM
P03956 BXGT006120 Interstitial collagenase reviewed Enzyme MMP1 Ki - - -
P14780 BXGT008053 Matrix metalloproteinase-9 reviewed Enzyme MMP9 Ki - - -
Q01959 BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 Ki - - -
P35367 BXGT009821 Histamine H1 receptor reviewed G-protein coupled receptor HRH1 Ki - - -
P15127 BXGT008085 Insulin receptor reviewed - Insr Ki - - -
P41968 BXGT010275 Melanocortin receptor 3 reviewed G-protein coupled receptor MC3R Ki - - -
P21397 BXGT008644 Amine oxidase [flavin-containing] A reviewed - MAOA IC50 - - -
P08912 BXGT006840 Muscarinic acetylcholine receptor M5 reviewed G-protein coupled receptor CHRM5 Ki - - -
P29466 BXGT009349 Caspase-1 reviewed Enzyme CASP1 IC50 - - -
P03956 BXGT006120 Interstitial collagenase reviewed Enzyme MMP1 IC50 - - -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Inhibition '=' 105 %
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki '=' 103 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki '=' 1516 nM
Q08209 BXGT012968 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform reviewed - PPP3CA IC50 - - -
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 IC50 - - -
P25103 BXGT009020 Substance-P receptor reviewed G-protein coupled receptor TACR1 IC50 - - -
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 Ki - - -
P11509 BXGT007716 Cytochrome P450 2A6 reviewed - CYP2A6 Ki - - -
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 Ki - - -
P34972 BXGT009779 Cannabinoid receptor 2 reviewed G-protein coupled receptor CNR2 Activity - - -
P32300 BXGT009618 Delta-type opioid receptor reviewed - Oprd1 Ke '=' 0 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 Ki - - -
P51589 BXGT010867 Cytochrome P450 2J2 reviewed - CYP2J2 IC50 '>' 50000 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki '=' 354 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki '=' 0 nM
Q9HAW9 BXGT020510 UDP-glucuronosyltransferase 1-8 reviewed - UGT1A8 Activity '=' 81 pm/min/mg
P54855 BXGT011088 UDP-glucuronosyltransferase 2B15 reviewed - UGT2B15 Activity '=' 0 pm/min/mg
P22309 BXGT008753 UDP-glucuronosyltransferase 1-1 reviewed - UGT1A1 Activity '=' 0 pm/min/mg
P37288 BXGT009977 Vasopressin V1a receptor reviewed G-protein coupled receptor AVPR1A IC50 - - -
Q06278 BXGT012869 Aldehyde oxidase reviewed Enzyme AOX1 Fm '=' 0 -
O76074 BXGT005174 cGMP-specific 3',5'-cyclic phosphodiesterase reviewed - PDE5A IC50 - - -
P29477 BXGT009355 Nitric oxide synthase, inducible reviewed - Nos2 Ki - - -
O76074 BXGT005174 cGMP-specific 3',5'-cyclic phosphodiesterase reviewed - PDE5A Ki - - -
P21917 BXGT008707 D(4) dopamine receptor reviewed G-protein coupled receptor DRD4 IC50 - - -
P14780 BXGT008053 Matrix metalloproteinase-9 reviewed Enzyme MMP9 IC50 - - -
Q9Y271 BXGT022222 Cysteinyl leukotriene receptor 1 reviewed G-protein coupled receptor CYSLTR1 IC50 - - -
P17252 BXGT008294 Protein kinase C alpha type reviewed Kinase PRKCA IC50 - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 pKb '=' 9 -
P08912 BXGT006840 Muscarinic acetylcholine receptor M5 reviewed G-protein coupled receptor CHRM5 IC50 - - -
P29274 BXGT009327 Adenosine receptor A2a reviewed G-protein coupled receptor ADORA2A IC50 - - -
P18825 BXGT008426 Alpha-2C adrenergic receptor reviewed G-protein coupled receptor ADRA2C IC50 - - -
P07943 BXGT006700 Aldo-keto reductase family 1 member B1 reviewed - Akr1b1 IC50 - - -
P29476 BXGT009354 Nitric oxide synthase, brain reviewed - Nos1 IC50 - - -
P30988 BXGT009491 Calcitonin receptor reviewed G-protein coupled receptor CALCR Ki - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 IC50 '=' 45 nM
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 Ki - - -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Activity - - -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ki '=' 362 nM
Q92887 BXGT019389 Canalicular multispecific organic anion transporter 1 reviewed Transporter ABCC2 IC50 '=' 133000 nM
P06241 BXGT006429 Tyrosine-protein kinase Fyn reviewed Kinase FYN Ki - - -
P08575 BXGT006793 Receptor-type tyrosine-protein phosphatase C reviewed Enzyme PTPRC Ki - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Inhibition '=' 100 %
P08913 BXGT006841 Alpha-2A adrenergic receptor reviewed G-protein coupled receptor ADRA2A IC50 - - -
P05181 BXGT006337 Cytochrome P450 2E1 reviewed - CYP2E1 Ki - - -
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 IC50 - - -
P00533 BXGT005575 Epidermal growth factor receptor reviewed Kinase EGFR Ki - - -
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 IC50 - - -
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 Ki - - -
P25100 BXGT009017 Alpha-1D adrenergic receptor reviewed G-protein coupled receptor ADRA1D Ki - - -
P25025 BXGT009006 C-X-C chemokine receptor type 2 reviewed G-protein coupled receptor CXCR2 Ki - - -
P30411 BXGT009424 B2 bradykinin receptor reviewed G-protein coupled receptor BDKRB2 Ki - - -
P51679 BXGT010877 C-C chemokine receptor type 4 reviewed G-protein coupled receptor CCR4 IC50 - - -
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 Ki '=' 15 nM
P00533 BXGT005575 Epidermal growth factor receptor reviewed Kinase EGFR IC50 - - -
P19327 BXGT008472 5-hydroxytryptamine receptor 1A reviewed - Htr1a Ki - - -
P28335 BXGT009255 5-hydroxytryptamine receptor 2C reviewed G-protein coupled receptor HTR2C IC50 - - -
P50406 BXGT010796 5-hydroxytryptamine receptor 6 reviewed G-protein coupled receptor HTR6 IC50 - - -
Q16539 BXGT013634 Mitogen-activated protein kinase 14 reviewed Kinase MAPK14 Ki - - -
P28564 BXGT009272 5-hydroxytryptamine receptor 1B reviewed - Htr1b IC50 - - -
P32241 BXGT009613 Vasoactive intestinal polypeptide receptor 1 reviewed G-protein coupled receptor VIPR1 IC50 - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Activity - - -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Activity - - -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Activity - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Inhibition - - -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Inhibition - - -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Inhibition - - -
P25103 BXGT009020 Substance-P receptor reviewed G-protein coupled receptor TACR1 Ki - - -
P16662 BXGT008253 UDP-glucuronosyltransferase 2B7 reviewed - UGT2B7 Activity - - -
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 ln Kt '=' 19 -
P79350 BXGT011862 Mu-type opioid receptor reviewed - OPRM1 Activity '=' 70 -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki '=' 30 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ki '=' 15 nM
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 Ki - - -
P20781 BXGT008598 Glycine receptor subunit beta reviewed - Glrb Ki - - -
P07727 BXGT006662 Glycine receptor subunit alpha-1 reviewed - Glra1 Ki - - -
P24524 BXGT008974 Glycine receptor subunit alpha-3 reviewed - Glra3 Ki - - -
P22771 BXGT008806 Glycine receptor subunit alpha-2 reviewed - Glra2 Ki - - -
P19327 BXGT008472 5-hydroxytryptamine receptor 1A reviewed - Htr1a IC50 - - -
P21554 BXGT008662 Cannabinoid receptor 1 reviewed G-protein coupled receptor CNR1 Activity - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 IC50 '=' 1 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ke '=' 35 nM
P21554 BXGT008662 Cannabinoid receptor 1 reviewed G-protein coupled receptor CNR1 Inhibition - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 IC50 '=' 5 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 IC50 '=' 5 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 IC50 '=' 5 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 ED50 - - -
P24557 BXGT008976 Thromboxane-A synthase reviewed - TBXAS1 Ki - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 IC50 '=' 94 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Inhibition - - -
O60656 BXGT004889 UDP-glucuronosyltransferase 1-9 reviewed - UGT1A9 CL '=' 0 mL.min-1.g-1
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Inhibition '=' 93 %
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Inhibition '=' 92 %
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Inhibition '=' 95 %
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Inhibition '=' 94 %
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 Ki '=' 2 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Inhibition '=' 83 %
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 Ki '=' 3 nM
O15438 BXGT004168 Canalicular multispecific organic anion transporter 2 reviewed Transporter ABCC3 IC50 '=' 133000 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00402 Opium poppy Papaver somniferum Herbs and Spices
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease