Showing entry for Morphine


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0030901
Compound NameMorphine
Structure
FormulaC17H19NO3
InchiKeyBQJCRHHNABKAKU-KBQPJGBKSA-N
SMILESO[C@H]1C=C[C@@H]2[C@@]34[C@H]1Oc1c4c(C[C@H]2N(CC3)C)ccc1O
InchiInChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1
IUPAC(4R,4aR,7S,7aR,12bS)-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7,9-diol
Molecular Weight285.14
Pubchem Id5288826
Chembl IdCHEMBL70
Targets of Information Source
DrugBank DB00295
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 approved; investigational agonist
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 approved; investigational agonist
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 approved; investigational agonist
Q9Y6Y9 BXGT022346 Lymphocyte antigen 96 reviewed Receptor LY96 approved; investigational activator
PDB MOI
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Q9D9B8 BXGT020264 Uncharacterized protein unreviewed Igh-VJ558 - - - ~1 -
Binding DB 50000092
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT009621 5-hydroxytryptamine receptor 7 reviewed Htr7 >10000 - - -
reviewed BXGT009780 Kappa-type opioid receptor reviewed Oprk1 1.2 - - -
reviewed BXGT009780 Kappa-type opioid receptor reviewed Oprk1 20 - - -
reviewed BXGT009780 Kappa-type opioid receptor reviewed Oprk1 0.6 - - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 0.4 - - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 0.3 - - -
reviewed BXGT009618 Delta-type opioid receptor reviewed Oprd1 320 - - -
reviewed BXGT019577 Beta-arrestin-1 reviewed ARRB1 358 - - -
reviewed BXGT011860 Delta-type opioid receptor (Fragment) reviewed OPRD1 86.7 - - -
reviewed BXGT011862 Mu-type opioid receptor reviewed OPRM1 4.8 - - -
reviewed BXGT011862 Mu-type opioid receptor reviewed OPRM1 27.5 - - -
reviewed BXGT012199 Mu-type opioid receptor (Fragment) reviewed OPRM1 2.69 - - -
reviewed BXGT009565 Sodium-dependent serotonin transporter reviewed Slc6a4 >10000 - - -
reviewed BXGT009729 Delta-type opioid receptor reviewed Oprd1 >10000 - - -
reviewed BXGT009729 Delta-type opioid receptor reviewed Oprd1 145 - - -
reviewed BXGT009780 Kappa-type opioid receptor reviewed Oprk1 >10000 - - -
reviewed BXGT009780 Kappa-type opioid receptor reviewed Oprk1 23.4 - - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 >10000 - - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 1.24 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 2 - - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 22 - - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 100 - - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 11.1 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 1.02 - - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 1000 - - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 538 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 14 - - -
reviewed BXGT006896 Neuronal acetylcholine receptor subunit alpha-4 reviewed Chrna4 >10000 - - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 140 - - -
reviewed BXGT011860 Delta-type opioid receptor (Fragment) reviewed OPRD1 50 - - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 46.9 - - -
reviewed BXGT010224 Kappa-type opioid receptor reviewed OPRK1 33.9 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 1.1 - - -
reviewed BXGT012199 Mu-type opioid receptor (Fragment) reviewed OPRM1 2 - - -
reviewed BXGT010343 Mu-type opioid receptor reviewed Oprm1 1.68 - - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 1.04 - - -
reviewed BXGT010343 Mu-type opioid receptor reviewed Oprm1 0.45 - - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 0.82 - - -
reviewed BXGT009618 Delta-type opioid receptor reviewed Oprd1 32.6 - - -
reviewed BXGT010224 Kappa-type opioid receptor reviewed OPRK1 217 - - -
reviewed BXGT012199 Mu-type opioid receptor (Fragment) reviewed OPRM1 1 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 2.2 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 0.32 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 - - - 34
reviewed BXGT019692 Mas-related G-protein coupled receptor member X2 reviewed G-protein coupled receptor MRGPRX2 - - - 6600
reviewed BXGT019692 Mas-related G-protein coupled receptor member X2 reviewed G-protein coupled receptor MRGPRX2 - - - 6200
reviewed BXGT011862 Mu-type opioid receptor reviewed OPRM1 2.5 - - -
reviewed BXGT011862 Mu-type opioid receptor reviewed OPRM1 0.5 - - -
reviewed BXGT010224 Kappa-type opioid receptor reviewed OPRK1 49 - - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 280 - - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 33 - - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 51 - - -
reviewed BXGT010224 Kappa-type opioid receptor reviewed OPRK1 - 130 - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 - 430 - -
reviewed BXGT012199 Mu-type opioid receptor (Fragment) reviewed OPRM1 - 8.5 - -
reviewed BXGT010224 Kappa-type opioid receptor reviewed OPRK1 1870 - - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 510 - - -
reviewed BXGT012199 Mu-type opioid receptor (Fragment) reviewed OPRM1 38 - - -
reviewed BXGT010224 Kappa-type opioid receptor reviewed OPRK1 110 - - -
reviewed BXGT012199 Mu-type opioid receptor (Fragment) reviewed OPRM1 6.5 - - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 710 - - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 456 - - -
reviewed BXGT012199 Mu-type opioid receptor (Fragment) reviewed OPRM1 3.3 - - -
reviewed BXGT010224 Kappa-type opioid receptor reviewed OPRK1 301 - - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - 1.6 - -
reviewed BXGT010224 Kappa-type opioid receptor reviewed OPRK1 - 2390 - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 460 - - -
reviewed BXGT010224 Kappa-type opioid receptor reviewed OPRK1 151 - - -
reviewed BXGT012199 Mu-type opioid receptor (Fragment) reviewed OPRM1 0.88 - - -
reviewed BXGT010224 Kappa-type opioid receptor reviewed OPRK1 24 - - -
reviewed BXGT009618 Delta-type opioid receptor reviewed Oprd1 - 736 - -
reviewed BXGT009730 Kappa-type opioid receptor reviewed Oprk1 1549 - - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 630 - - -
reviewed BXGT012199 Mu-type opioid receptor (Fragment) reviewed OPRM1 7.7 - - -
reviewed BXGT012199 Mu-type opioid receptor (Fragment) reviewed OPRM1 - 72 - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 113 - - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 2.1 - - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 0.78 - - -
reviewed BXGT012199 Mu-type opioid receptor (Fragment) reviewed OPRM1 - 77 - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - 0.81 - -
reviewed BXGT010224 Kappa-type opioid receptor reviewed OPRK1 - 530 - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 - 185 - -
reviewed BXGT012199 Mu-type opioid receptor (Fragment) reviewed OPRM1 - 4 - -
reviewed BXGT012199 Mu-type opioid receptor (Fragment) reviewed OPRM1 - 70 - -
reviewed BXGT010224 Kappa-type opioid receptor reviewed OPRK1 167 - - -
reviewed BXGT010224 Kappa-type opioid receptor reviewed OPRK1 86 - - -
reviewed BXGT012199 Mu-type opioid receptor (Fragment) reviewed OPRM1 1.8 - - -
reviewed BXGT012199 Mu-type opioid receptor (Fragment) reviewed OPRM1 - 38 - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 375 - - -
reviewed BXGT010343 Mu-type opioid receptor reviewed Oprm1 - 1420 - -
reviewed BXGT010224 Kappa-type opioid receptor reviewed OPRK1 - 1.8 - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - 0.14 - -
reviewed BXGT009729 Delta-type opioid receptor reviewed Oprd1 - 7.4 - -
reviewed BXGT010224 Kappa-type opioid receptor reviewed OPRK1 69 - - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 132 - - -
reviewed BXGT010224 Kappa-type opioid receptor reviewed OPRK1 330 - - -
reviewed BXGT010224 Kappa-type opioid receptor reviewed OPRK1 - 271 - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 150 - - -
reviewed BXGT019955 Sigma non-opioid intracellular receptor 1 reviewed SIGMAR1 >100000 - - -
reviewed BXGT009730 Kappa-type opioid receptor reviewed Oprk1 301 - - -
reviewed BXGT010224 Kappa-type opioid receptor reviewed OPRK1 6424 - - -
reviewed BXGT011862 Mu-type opioid receptor reviewed OPRM1 0.9 - - -
reviewed BXGT012199 Mu-type opioid receptor (Fragment) reviewed OPRM1 - 59 - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 17 - - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 2.8 - - -
reviewed BXGT009729 Delta-type opioid receptor reviewed Oprd1 90 - - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 1.8 - - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 - - - 16
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 605 - - -
reviewed BXGT009730 Kappa-type opioid receptor reviewed Oprk1 - 258 - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 - 1 - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 - 217 - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 - 242 - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 - 150 - -
reviewed BXGT012199 Mu-type opioid receptor (Fragment) reviewed OPRM1 3 - - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 299 - - -
reviewed BXGT010224 Kappa-type opioid receptor reviewed OPRK1 188 - - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 58 - - -
reviewed BXGT010584 Nociceptin receptor reviewed OPRL1 14 - - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 - - - 316
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 47 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 - - - 316
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 - - - 16
reviewed BXGT009618 Delta-type opioid receptor reviewed Oprd1 - 644 - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 260 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 4.6 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 1.9 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 4 - - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 52 - - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 295 - - -
reviewed BXGT010343 Mu-type opioid receptor reviewed Oprm1 1.8 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 5.2 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 - - - 10
reviewed BXGT010343 Mu-type opioid receptor reviewed Oprm1 1.2 - - -
reviewed BXGT009618 Delta-type opioid receptor reviewed Oprd1 100 - - -
reviewed BXGT010343 Mu-type opioid receptor reviewed Oprm1 - - - 120
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 2.6 - - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 299 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 22 - - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 1.5 - - -
reviewed BXGT009729 Delta-type opioid receptor reviewed Oprd1 83 - - -
reviewed BXGT010224 Kappa-type opioid receptor reviewed OPRK1 28 - - -
reviewed BXGT012199 Mu-type opioid receptor (Fragment) reviewed OPRM1 - 29 - -
reviewed BXGT009618 Delta-type opioid receptor reviewed Oprd1 - 155 - -
reviewed BXGT010224 Kappa-type opioid receptor reviewed OPRK1 35 - - -
reviewed BXGT012199 Mu-type opioid receptor (Fragment) reviewed OPRM1 3.9 - - -
reviewed BXGT009729 Delta-type opioid receptor reviewed Oprd1 2 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 - 6.3 - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 120 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 0.53 - - -
reviewed BXGT009780 Kappa-type opioid receptor reviewed Oprk1 27 - - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 3 - - -
reviewed BXGT009729 Delta-type opioid receptor reviewed Oprd1 15 - - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - - - 123.5
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 6.9 - - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 116.8 - - -
reviewed BXGT009729 Delta-type opioid receptor reviewed Oprd1 76.9 - - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - 5.64 - -
reviewed BXGT010343 Mu-type opioid receptor reviewed Oprm1 - - - 85.5
reviewed BXGT009729 Delta-type opioid receptor reviewed Oprd1 - 404 - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 4.8 - - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - - - 0
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - 11 - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 - 250 - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 - 10 - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 190 - - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 6 - - -
reviewed BXGT009730 Kappa-type opioid receptor reviewed Oprk1 - 27 - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - 27 - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - 4.2 - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - 73 - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - 4.5 - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 - 24 - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - 0.05 - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - 0.75 - -
reviewed BXGT011367 D(2) dopamine receptor reviewed Drd2 - 120 - -
reviewed BXGT011367 D(2) dopamine receptor reviewed Drd2 - 5.4 - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - 0 - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - 8.6 - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - 0.027 - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 - 29 - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - 160 - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - - - 3
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 - 65 - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 6.6 - - -
reviewed BXGT009729 Delta-type opioid receptor reviewed Oprd1 113 - - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 - - - 484
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - 487 - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - 226 - -
reviewed BXGT012199 Mu-type opioid receptor (Fragment) reviewed OPRM1 2.2 - - -
reviewed BXGT009729 Delta-type opioid receptor reviewed Oprd1 1.8 - - -
reviewed BXGT012199 Mu-type opioid receptor (Fragment) reviewed OPRM1 1.98 - - -
reviewed BXGT010224 Kappa-type opioid receptor reviewed OPRK1 54.3 - - -
reviewed BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 - 28 - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 38 - - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 1900 - - -
reviewed BXGT019955 Sigma non-opioid intracellular receptor 1 reviewed SIGMAR1 >10000 - - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - - - 21
reviewed BXGT009618 Delta-type opioid receptor reviewed Oprd1 - 390 - -
reviewed BXGT012199 Mu-type opioid receptor (Fragment) reviewed OPRM1 - 57 - -
reviewed BXGT009729 Delta-type opioid receptor reviewed Oprd1 280 - - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 2.2 - - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 5.7 - - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 86 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 1.8 - - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - 3.9 - -
reviewed BXGT009729 Delta-type opioid receptor reviewed Oprd1 - 205 - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 36 - - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 2 - - -
reviewed BXGT009729 Delta-type opioid receptor reviewed Oprd1 - 684 - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - 1.9 - -
reviewed BXGT009729 Delta-type opioid receptor reviewed Oprd1 684 - - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 8.1 - - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 - 1705 - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 - 0.57 - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 3 - - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 64 - - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 6.55 - - -
reviewed BXGT009729 Delta-type opioid receptor reviewed Oprd1 217 - - -
reviewed BXGT009780 Kappa-type opioid receptor reviewed Oprk1 113 - - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 1 - - -
reviewed BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 - >50000 - -
reviewed BXGT006507 ATP-dependent translocase ABCB1 reviewed Abcb1b - >50000 - -
reviewed BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 - >50000 - -
reviewed BXGT008651 ATP-dependent translocase ABCB1 reviewed Abcb1a - >50000 - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 113 - - -
reviewed BXGT009729 Delta-type opioid receptor reviewed Oprd1 157 - - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 11 - - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 24 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 0.88 - - -
reviewed BXGT009618 Delta-type opioid receptor reviewed Oprd1 - 1600 - -
reviewed BXGT012199 Mu-type opioid receptor (Fragment) reviewed OPRM1 - 311 - -
reviewed BXGT010224 Kappa-type opioid receptor reviewed OPRK1 113 - - -
reviewed BXGT010224 Kappa-type opioid receptor reviewed OPRK1 34 - - -
reviewed BXGT012199 Mu-type opioid receptor (Fragment) reviewed OPRM1 2.5 - - -
reviewed BXGT010343 Mu-type opioid receptor reviewed Oprm1 - - - 395
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - 9770 - -
reviewed BXGT012199 Mu-type opioid receptor (Fragment) reviewed OPRM1 - 29300 - -
reviewed BXGT009618 Delta-type opioid receptor reviewed Oprd1 - 155000 - -
reviewed BXGT009729 Delta-type opioid receptor reviewed Oprd1 - 112200 - -
reviewed BXGT010343 Mu-type opioid receptor reviewed Oprm1 - 1.27 - -
reviewed BXGT009730 Kappa-type opioid receptor reviewed Oprk1 - 145.1 - -
reviewed BXGT010224 Kappa-type opioid receptor reviewed OPRK1 - 213.1 - -
reviewed BXGT009618 Delta-type opioid receptor reviewed Oprd1 - >1000 - -
reviewed BXGT010343 Mu-type opioid receptor reviewed Oprm1 - 1.3 - -
reviewed BXGT004141 Solute carrier family 22 member 1 reviewed Transporter SLC22A1 - 28000 - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 33.7 - - -
reviewed BXGT004559 Acetylcholinesterase reviewed ache 109000 - - -
reviewed BXGT010224 Kappa-type opioid receptor reviewed OPRK1 >10000 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 2.5 - - -
reviewed BXGT012199 Mu-type opioid receptor (Fragment) reviewed OPRM1 1.1 - - -
reviewed BXGT010224 Kappa-type opioid receptor reviewed OPRK1 46.9 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 - - - 3.7
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 0.14 - - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 13 - - -
reviewed BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 - 4.3 - -
reviewed BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 - 1000000 - -
reviewed BXGT009729 Delta-type opioid receptor reviewed Oprd1 171 - - -
reviewed BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 61 - - -
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 - - - 194
reviewed BXGT009731 Mu-type opioid receptor reviewed Oprm1 6.3 - - -
CHEMBL CHEMBL70
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Relative affinity '=' 0 %
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 Relative affinity '=' 0 %
Q12809 BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 IC50 '=' 1000000 nM
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 IC50 '=' 38 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki '=' 629 nM
P42866 BXGT010343 Mu-type opioid receptor reviewed - Oprm1 IC50 '=' 1 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 IC50 '=' 22 nM
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 IC50 '=' 22 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 IC50 '=' 22 nM
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 IC50 '=' 213 nM
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 Ki '=' 167 nM
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 Relative Potency '=' 1 -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki '=' 0 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 IC50 '=' 27 nM
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 IC50 '=' 27 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 IC50 '=' 27 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Ki '=' 6 nM
P33534 BXGT009730 Kappa-type opioid receptor reviewed - Oprk1 Ki '=' 301 nM
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 Inhibition - - -
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Ki '=' 11 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ki '=' 299 nM
P32300 BXGT009618 Delta-type opioid receptor reviewed - Oprd1 IC50 '=' 390 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ki '=' 60 nM
P06795 BXGT006507 ATP-dependent translocase ABCB1 reviewed - Abcb1b IC50 '>' 50000 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki '=' 150 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Activity '=' 103 %
P42866 BXGT010343 Mu-type opioid receptor reviewed - Oprm1 IC50 '=' 1420 nM
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 Ki '=' 151 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 IC50 '=' 65 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 IC50 '=' 65 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 IC50 '=' 65 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Ratio '=' 0 -
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 Ratio '=' 0 -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki '=' 3 nM
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 IC50 '=' 29 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 ln Kt '=' 18 -
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Activity '=' 3 nM/mg*min
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki '=' 2 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ki '=' 1900 nM
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 Ki '=' 468 nM
G3H1Y1 BXGT003473 Delta-type opioid receptor unreviewed - I79_004173 Inhibition '=' 95 %
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 EC50 '=' 39 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki '=' 2 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 EC50 - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki '=' 1 nM
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 Ki '=' 49 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Ki '=' 116 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 IC50 '>' 50000 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki '=' 17 nM
Q9HAW9 BXGT020510 UDP-glucuronosyltransferase 1-8 reviewed - UGT1A8 Activity '=' 35 pm/min/mg
P22310 BXGT008754 UDP-glucuronosyltransferase 1-4 reviewed - UGT1A4 Activity '=' 0 pm/min/mg
P21397 BXGT008644 Amine oxidase [flavin-containing] A reviewed - MAOA Activity - - -
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 IC50 '=' 311 nM
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 IC50 '=' 71 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 Ki '=' 82 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Ki '=' 4 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki '=' 104 nM
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 Ki '=' 86 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Activity '=' 2 %
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Activity '=' 3 nM
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 Activity '=' 3 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 Activity '=' 3 nM
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 IC50 '=' 29300 nM
P32300 BXGT009618 Delta-type opioid receptor reviewed - Oprd1 Ke '=' 7 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki '=' 295 nM
Q9HAW8 BXGT020509 UDP-glucuronosyltransferase 1-10 reviewed - UGT1A10 Activity '=' 0 pm/min/mg
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Activity - - -
P08913 BXGT006841 Alpha-2A adrenergic receptor reviewed G-protein coupled receptor ADRA2A Activity - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki '=' 2 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 IC50 '=' 3 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Ratio '=' 0 -
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 Ratio '=' 0 -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 EC50 '=' 484 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 IC50 '=' 404 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 ED50 '=' 316 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 EC50 '=' 6 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Ki '=' 2 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 IC50 '=' 28 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 IC50 '=' 28 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 IC50 '=' 28 nM
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 Dose ratio '=' 45 -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ki '=' 6 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 IC50 '=' 1 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Activity '=' 22 %
P08913 BXGT006841 Alpha-2A adrenergic receptor reviewed G-protein coupled receptor ADRA2A Activity '=' 22 %
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 IC50 '=' 130 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 IC50 '=' 430 nM
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 Ki '=' 38 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Activity '=' 93 %
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 Ke '=' 20 nM
P33534 BXGT009730 Kappa-type opioid receptor reviewed - Oprk1 IC50 '=' 145 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki '=' 0 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 IC50 '=' 2 nM
P33534 BXGT009730 Kappa-type opioid receptor reviewed - Oprk1 Ke '=' 4 nM
P32300 BXGT009618 Delta-type opioid receptor reviewed - Oprd1 ED50 ratio '=' 1 -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Relative potency '=' 1 -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Relative potency '=' 1 -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Relative potency '=' 1 -
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Ki '=' 1 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 Ki '=' 90 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki '=' 375 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 Ki '=' 15 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki '=' 510 nM
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 IC50 '=' 2390 nM
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 IC50 '=' 8 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 IC50 '=' 160 nM
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 IC50 '=' 160 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 IC50 '=' 160 nM
P42866 BXGT010343 Mu-type opioid receptor reviewed - Oprm1 Ki '=' 1 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Ki '=' 2 nM
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 Ki '=' 24 nM
P32300 BXGT009618 Delta-type opioid receptor reviewed - Oprd1 IC50 '=' 736 nM
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 Ki '=' 301 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Ki '=' 1 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 Ki '=' 113 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ki '=' 64 nM
P32300 BXGT009618 Delta-type opioid receptor reviewed - Oprd1 IC50 '=' 1600 nM
P42866 BXGT010343 Mu-type opioid receptor reviewed - Oprm1 Emax '=' 24 %
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Activity - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 IC50 '=' 0 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 IC50 '=' 29 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 IC50 '=' 29 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 IC50 '=' 29 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki '=' 38 nM
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 Ki '=' 3 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 IC50 '=' 73 nM
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 IC50 '=' 73 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 IC50 '=' 73 nM
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 Ki '=' 0 nM
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 Ki '>' 10000 nM
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 IC50 '=' 271 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Activity '=' 209 %
P21447 BXGT008651 ATP-dependent translocase ABCB1 reviewed - Abcb1a IC50 '>' 50000 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Activity '=' 103 %
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 IC50 '=' 1705 nM
P35503 BXGT009840 UDP-glucuronosyltransferase 1-3 reviewed - UGT1A3 Vmax '=' 38 pmol/min/mg protein
P79350 BXGT011862 Mu-type opioid receptor reviewed - OPRM1 Activity '=' 67 -
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 Ki '=' 157 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 IC50 '=' 5 nM
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 Ki '=' 113 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Ki '=' 0 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki '=' 2 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 EC50 '=' 15 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ratio '=' 0 -
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 EC50 '=' 3 nM
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 EC50 '=' 3 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 EC50 '=' 3 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Ratio '=' 2 -
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 Ratio '=' 2 -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 EC50 '=' 500 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Inhibition '=' 91 %
P33534 BXGT009730 Kappa-type opioid receptor reviewed - Oprk1 Inhibition '=' 71 %
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Emax '=' 134 %
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki '=' 140 nM
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 Ki '=' 188 nM
P47748 BXGT010584 Nociceptin receptor reviewed - OPRL1 Ki '=' 13 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Selectivity '=' 127 -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Selectivity '=' 127 -
P21447 BXGT008651 ATP-dependent translocase ABCB1 reviewed - Abcb1a Ratio '=' 1 -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ki '=' 260 nM
P32300 BXGT009618 Delta-type opioid receptor reviewed - Oprd1 IC50 '=' 644 nM
P33534 BXGT009730 Kappa-type opioid receptor reviewed - Oprk1 Relative molar potency '=' 1 -
P32300 BXGT009618 Delta-type opioid receptor reviewed - Oprd1 Relative molar potency '=' 1 -
P42866 BXGT010343 Mu-type opioid receptor reviewed - Oprm1 Relative molar potency '=' 1 -
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Ki '=' 5 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Activity - - -
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 IC50 '<' 500 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki '=' 456 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki '=' 1 nM
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 IC50 '=' 70 nM
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 Ki '=' 27 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ki '=' 46 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Ki '=' 6 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Inhibition '=' 25 %
P08913 BXGT006841 Alpha-2A adrenergic receptor reviewed G-protein coupled receptor ADRA2A Inhibition '=' 25 %
O15245 BXGT004141 Solute carrier family 22 member 1 reviewed Transporter SLC22A1 Inhibition '=' 67 %
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Selectivity '=' 42 -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Selectivity '=' 42 -
P42866 BXGT010343 Mu-type opioid receptor reviewed - Oprm1 Inhibition - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 EC50 '=' 316 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Emax '=' 100 %
O42275 BXGT004559 Acetylcholinesterase reviewed - ache Ki '=' 109000 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 IC50 '=' 9770 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 ED50 '=' 37 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 IC50 '=' 0 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 IC50 '=' 150 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 IC50 '=' 8 nM
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 IC50 '=' 8 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 IC50 '=' 8 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Emax '=' 86 %
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 EC50 '=' 3 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Inhibition '=' 2 %
P21447 BXGT008651 ATP-dependent translocase ABCB1 reviewed - Abcb1a Ratio '=' 1 -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 IC50 - - -
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Inhibition '=' 1 %
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 Inhibition '=' 1 %
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 Inhibition '=' 1 %
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki '=' 132 nM
P33534 BXGT009730 Kappa-type opioid receptor reviewed - Oprk1 ED50 '=' 0 mg.kg-1
P32300 BXGT009618 Delta-type opioid receptor reviewed - Oprd1 ED50 '=' 0 mg.kg-1
P42866 BXGT010343 Mu-type opioid receptor reviewed - Oprm1 ED50 '=' 0 mg.kg-1
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 Ki '=' 684 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki '=' 460 nM
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 IC50 '=' 1 nM
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 IC50 '=' 4 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 Ki '=' 76 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki '=' 710 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 IC50 '=' 24 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 IC50 '=' 24 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 IC50 '=' 24 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Ki '=' 8 nM
P32300 BXGT009618 Delta-type opioid receptor reviewed - Oprd1 IC50 '=' 155000 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Inhibition '=' 69 %
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Activity '=' 62 %
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 Ki '>' 10000 nM
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 Ki - - -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Activity - - -
O15245 BXGT004141 Solute carrier family 22 member 1 reviewed Transporter SLC22A1 IC50 '=' 28000 nM
P33534 BXGT009730 Kappa-type opioid receptor reviewed - Oprk1 Ke '=' 53 nM
P42866 BXGT010343 Mu-type opioid receptor reviewed - Oprm1 Inhibition '=' 97 %
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ki '=' 65 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 EC50 '=' 7 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Activity '=' 62 -
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 EC50 '=' 123 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki '=' 280 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ki '=' 33 nM
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 IC50 '=' 77 nM
P21447 BXGT008651 ATP-dependent translocase ABCB1 reviewed - Abcb1a Ratio '=' 2 -
P42866 BXGT010343 Mu-type opioid receptor reviewed - Oprm1 Ke '=' 3 nM
P33534 BXGT009730 Kappa-type opioid receptor reviewed - Oprk1 Potency ratio '=' 0 -
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 Ki '=' 110 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 EC50 '=' 21 nM
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 Ki '=' 1870 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Log10ED50 '=' 7 -
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Selectivity '=' 33 -
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 Selectivity '=' 33 -
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 Ki '=' 217 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Selectivity ratio '=' 33 -
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 Selectivity ratio '=' 33 -
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 Ki '=' 7 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ratio Ki '=' 0 -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ratio Ki '=' 0 -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ki '=' 24 nM
P33534 BXGT009730 Kappa-type opioid receptor reviewed - Oprk1 Ki '=' 1549 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 EC50 - - -
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 Ki '=' 6424 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Emax '=' 202 %
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 Ki '=' 54 nM
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 Inhibition - - -
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 IC50 '=' 11 nM
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 IC50 '=' 11 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 IC50 '=' 11 nM
Q9NY46 BXGT021248 Sodium channel protein type 3 subunit alpha reviewed Ion channel SCN3A Inhibition '=' 5 %
Q99250 BXGT019913 Sodium channel protein type 2 subunit alpha reviewed Ion channel SCN2A Inhibition '=' 5 %
P35498 BXGT009838 Sodium channel protein type 1 subunit alpha reviewed Ion channel SCN1A Inhibition '=' 5 %
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 Inhibition - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 EC50 '=' 3 nM
P08913 BXGT006841 Alpha-2A adrenergic receptor reviewed G-protein coupled receptor ADRA2A EC50 '=' 3 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ratio '=' 46 -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ratio '=' 46 -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 EC50 '=' 10 nM
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 Ki '=' 28 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Log10ED50 '=' 7 -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki '=' 4 nM
P42866 BXGT010343 Mu-type opioid receptor reviewed - Oprm1 EC50 '=' 85 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki '=' 299 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 IC50 '=' 4 nM
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 Relative potency '=' 100 -
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 ED50 '=' 3 nM
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 ED50 '=' 3 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 ED50 '=' 3 nM
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 Ki '=' 2 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 IC50 '=' - -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 ED50 '=' 1140 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ki '=' 86 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Ki '=' 32 nM
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 Ki '=' 32 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 Ki '=' 32 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 IC50 '=' 250 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 IC50 '=' 250 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 IC50 '=' 250 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Emax '=' 28 %
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ratio '=' 0 -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ratio '=' 0 -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ratio '=' 5 -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ratio '=' 5 -
P16662 BXGT008253 UDP-glucuronosyltransferase 2B7 reviewed - UGT2B7 Activity '=' 3719 pm/min/mg
P06133 BXGT006414 UDP-glucuronosyltransferase 2B4 reviewed - UGT2B4 Activity '=' 0 pm/min/mg
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki '=' 1 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki '=' 416 nM
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 Relative affinity '=' 98 %
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Ki '=' 2 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki '=' 3 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 IC50 '=' 684 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 KiL '=' 113 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 KiH '=' 2 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 IC50 '=' 4 nM
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 IC50 '=' 4 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 IC50 '=' 4 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Selectivity '=' 27 -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Selectivity '=' 27 -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Selectivity '=' 6 -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Selectivity '=' 6 -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ki '=' 33 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki ratio '=' 0 -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki ratio '=' 0 -
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 IC50 '=' 0 nM
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 IC50 '=' 0 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 IC50 '=' 0 nM
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 IC50 '>' 50000 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 KT '=' 18 -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ratio Ki '=' 5 -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ratio Ki '=' 5 -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ke - - -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ke - - -
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Ki '=' 36 nM
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 Ki '=' 3 nM
Q98UH1 BXGT019904 Mu opioid receptor-like OR2 unreviewed - oprm1 Ki '=' 187 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 IC50 '=' 309 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 IC50 '=' 309 nM
Q99720 BXGT019955 Sigma non-opioid intracellular receptor 1 reviewed - SIGMAR1 Ki '>' 10000 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ki '=' 113 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Selectivity '=' 5 -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Selectivity '=' 5 -
P79350 BXGT011862 Mu-type opioid receptor reviewed - OPRM1 Ki '=' 2 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Ki '=' 2 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki '=' 51 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Control '=' 86 %
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Control '=' 86 %
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Control '=' 86 %
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 IC50 '=' 4 nM
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 IC50 '=' 4 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 IC50 '=' 4 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Ki '=' 1 nM
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 Ki '=' 1 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki '=' 4 nM
P21447 BXGT008651 ATP-dependent translocase ABCB1 reviewed - Abcb1a Activity - - -
P42866 BXGT010343 Mu-type opioid receptor reviewed - Oprm1 Ratio '=' 3 -
P79350 BXGT011862 Mu-type opioid receptor reviewed - OPRM1 Ki '=' 0 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Activity '=' 31 -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ki '=' 52 nM
P79350 BXGT011862 Mu-type opioid receptor reviewed - OPRM1 Ki '=' 0 nM
Q99720 BXGT019955 Sigma non-opioid intracellular receptor 1 reviewed - SIGMAR1 Ki '>' 100000 nM
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 Ki '=' 33 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki '=' 1 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 IC50 '=' 205 nM
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 Dose ratio '=' 7 -
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 Ki '=' 3 nM
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 IC50 '=' 530 nM
P35503 BXGT009840 UDP-glucuronosyltransferase 1-3 reviewed - UGT1A3 Km '=' 3280000 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Selectivity '=' 156 -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Selectivity '=' 156 -
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 IC50 '=' 58 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Kp '=' 12 -
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 EC50 '=' 194 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 IC50 '=' 1 nM
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 Ki '=' 6 nM
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 IC50 '=' 57 nM
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 Ki '=' 467 nM
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 Ki '=' 1 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ratio '=' 0 -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ratio '=' 0 -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ratio '=' 265 -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ratio '=' 0 -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ratio '=' 0 -
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 Ki '=' 69 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ki '=' 13 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ratio '=' 25 -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ratio '=' 25 -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ratio '=' 25 -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Inhibition '=' 81 %
P42866 BXGT010343 Mu-type opioid receptor reviewed - Oprm1 Ratio '=' 0 -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 EC50 '=' 316 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Kp '~' 300000 -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 IC50 '=' 185 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 Ki '=' 2 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Control '=' 75 %
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Control '=' 75 %
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Control '=' 75 %
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Ki '=' 3 nM
P33534 BXGT009730 Kappa-type opioid receptor reviewed - Oprk1 IC50 '=' 258 nM
P32300 BXGT009618 Delta-type opioid receptor reviewed - Oprd1 IC50 '=' 258 nM
P42866 BXGT010343 Mu-type opioid receptor reviewed - Oprm1 IC50 '=' 258 nM
P33534 BXGT009730 Kappa-type opioid receptor reviewed - Oprk1 IC50 '=' 27 nM
P32300 BXGT009618 Delta-type opioid receptor reviewed - Oprd1 IC50 '=' 27 nM
P42866 BXGT010343 Mu-type opioid receptor reviewed - Oprm1 IC50 '=' 27 nM
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 Ki '=' 113 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Ratio IC50 '=' 25 -
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 Ratio IC50 '=' 25 -
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 Ratio IC50 '=' 25 -
P42866 BXGT010343 Mu-type opioid receptor reviewed - Oprm1 EC50 '=' 30 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Activity '=' 8 %
P08913 BXGT006841 Alpha-2A adrenergic receptor reviewed G-protein coupled receptor ADRA2A Activity '=' 8 %
P32300 BXGT009618 Delta-type opioid receptor reviewed - Oprd1 ED50 '=' 0 mg.kg-1
P42866 BXGT010343 Mu-type opioid receptor reviewed - Oprm1 ED50 '=' 0 mg.kg-1
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Ratio '=' 130 -
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 Ratio '=' 130 -
P42866 BXGT010343 Mu-type opioid receptor reviewed - Oprm1 EC50 '=' 395 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Relative potency '=' 1 -
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 ln Kp '=' 12 -
P32300 BXGT009618 Delta-type opioid receptor reviewed - Oprd1 IC50 '>' 1000 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Relative molar potency '=' 1 -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Relative molar potency '=' 1 -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Relative molar potency '=' 1 -
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 IC50 '=' 112200 nM
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 Inhibition - - -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ki '=' 120 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 EC50 '=' 15 nM
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 Ki '=' 46 nM
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 Ki '=' 2 nM
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 Ki '=' 330 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki '=' 113 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 IC50 '=' 10 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 IC50 '=' 10 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 IC50 '=' 10 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 IC50 '=' - -
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Inhibition '=' 2 %
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 Inhibition '=' 2 %
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 Inhibition '=' 2 %
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki '=' 605 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 Activity '=' 1220 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 IC50 '=' 7 nM
P22309 BXGT008753 UDP-glucuronosyltransferase 1-1 reviewed - UGT1A1 Activity '=' 0 pm/min/mg
P19224 BXGT008468 UDP-glucuronosyltransferase 1-6 reviewed - UGT1A6 Activity '=' 0 pm/min/mg
O60656 BXGT004889 UDP-glucuronosyltransferase 1-9 reviewed - UGT1A9 Activity '=' 0 pm/min/mg
P16662 BXGT008253 UDP-glucuronosyltransferase 2B7 reviewed - UGT2B7 Activity '=' 2968 pm/min/mg
P0DTE4 BXGT022286 UDP-glucuronosyltransferase 2A1 reviewed - UGT2A1 Activity '=' 73 pm/min/mg
P16662 BXGT008253 UDP-glucuronosyltransferase 2B7 reviewed - UGT2B7 Activity '=' 160 pm/min/mg
P36537 BXGT009924 UDP-glucuronosyltransferase 2B10 reviewed - UGT2B10 Activity '=' 0 pm/min/mg
P16662 BXGT008253 UDP-glucuronosyltransferase 2B7 reviewed - UGT2B7 Activity '=' 0 pm/min/mg
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 Ki '=' 3 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 deltalog(Tau/KA) '=' 0 -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki '=' 0 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Selectivity ratio '=' 0 -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Selectivity ratio '=' 0 -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Inhibition - - -
P08913 BXGT006841 Alpha-2A adrenergic receptor reviewed G-protein coupled receptor ADRA2A Inhibition - - -
P08913 BXGT006841 Alpha-2A adrenergic receptor reviewed G-protein coupled receptor ADRA2A Activity - - -
P08913 BXGT006841 Alpha-2A adrenergic receptor reviewed G-protein coupled receptor ADRA2A Inhibition - - -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Activity - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Emax '=' 77 %
P54855 BXGT011088 UDP-glucuronosyltransferase 2B15 reviewed - UGT2B15 Activity '=' 0 pm/min/mg
Q60492 BXGT015986 Sigma non-opioid intracellular receptor 1 reviewed - SIGMAR1 Ki - - -
P16662 BXGT008253 UDP-glucuronosyltransferase 2B7 reviewed - UGT2B7 Activity '=' 2536 pm/min/mg
Q9HAW9 BXGT020510 UDP-glucuronosyltransferase 1-8 reviewed - UGT1A8 Activity '=' 15 pm/min/mg
P35503 BXGT009840 UDP-glucuronosyltransferase 1-3 reviewed - UGT1A3 Activity '=' 21 pm/min/mg
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Activity '=' 93 %
P42866 BXGT010343 Mu-type opioid receptor reviewed - Oprm1 IC50 '=' 1 nM
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 Inhibition - - -
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 Ki '=' 1 nM
O95342 BXGT005373 Bile salt export pump reviewed Transporter ABCB11 IC50 '>' 135000 nM
P42866 BXGT010343 Mu-type opioid receptor reviewed - Oprm1 Activity '=' 1 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 IC50 '=' 6 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Emax '=' 57 %
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Kt '=' 150000000 -
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 Ki '=' 280 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 Ki '=' 1 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Emax '=' 103 %
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 EC50 '=' 6 nM
G3HZR5 BXGT003475 Kappa-type opioid receptor unreviewed - I79_016575 Inhibition '=' 95 %
P42866 BXGT010343 Mu-type opioid receptor reviewed - Oprm1 EC50 '=' 120 nM
P32300 BXGT009618 Delta-type opioid receptor reviewed - Oprd1 IC50 '<' 500 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 Ki '=' 171 nM
B3DH72 BXGT002031 Opioid receptor, delta 1b unreviewed - oprd1b Ki '=' 1427 nM
P41144 BXGT010224 Kappa-type opioid receptor reviewed - OPRK1 Ki '=' 35 nM
G3HZR5 BXGT003475 Kappa-type opioid receptor unreviewed - I79_016575 Inhibition '=' 100 %
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki '=' 22 nM
P42866 BXGT010343 Mu-type opioid receptor reviewed - Oprm1 Emax '=' 106 %
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 IC50 - - -
P42866 BXGT010343 Mu-type opioid receptor reviewed - Oprm1 Ki '=' 4 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 deltalog(Tau/KA) '=' 0 -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 EC50 '=' 50 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki '=' 5 nM
P33534 BXGT009730 Kappa-type opioid receptor reviewed - Oprk1 Log AP '=' 5 -
P32300 BXGT009618 Delta-type opioid receptor reviewed - Oprd1 Log AP '=' 5 -
P42866 BXGT010343 Mu-type opioid receptor reviewed - Oprm1 Log AP '=' 5 -
P33534 BXGT009730 Kappa-type opioid receptor reviewed - Oprk1 ED50 '=' 6 umol.kg-1
P32300 BXGT009618 Delta-type opioid receptor reviewed - Oprd1 ED50 '=' 6 umol.kg-1
P42866 BXGT010343 Mu-type opioid receptor reviewed - Oprm1 ED50 '=' 6 umol.kg-1
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 EC50 '=' 34 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki '=' 0 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki '=' 58 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 EC50 '=' 501 nM
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 Ki '=' 3 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 Ki '>' 10000 nM
Q98UH1 BXGT019904 Mu opioid receptor-like OR2 unreviewed - oprm1 Ki '=' 187 nM
P32300 BXGT009618 Delta-type opioid receptor reviewed - Oprd1 IC50 '=' 155 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 IC50 '=' 250 nM
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 IC50 '=' 250 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 IC50 '=' 250 nM
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 Activity - - -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 EC50 '=' 400 nM
P33535 BXGT009731 Mu-type opioid receptor reviewed - Oprm1 IC50 '=' 10 nM
P34975 BXGT009780 Kappa-type opioid receptor reviewed - Oprk1 IC50 '=' 10 nM
P33533 BXGT009729 Delta-type opioid receptor reviewed - Oprd1 IC50 '=' 10 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 deltalog(Tau/KA) '=' 0 -
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Inhibition '=' 90 %
P33534 BXGT009730 Kappa-type opioid receptor reviewed - Oprk1 EC50 '=' 400 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Inhibition '=' 80 %
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Inhibition '=' 61 %
P97266 BXGT012199 Mu-type opioid receptor reviewed - OPRM1 Ki '=' 5 nM
O57585 BXGT004756 Opioid receptor homologue unreviewed - oprd1a Ki '=' 223 nM
G3H1Y1 BXGT003473 Delta-type opioid receptor unreviewed - I79_004173 Inhibition '=' 72 %
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Inhibition '=' 98 %
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Inhibition '=' 42 %
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Inhibition '=' 85 %
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ratio '=' 1 -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 EC50 '=' 379 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 EC50 '=' 64 nM
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Emax '=' 83 %
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki '=' 340 nM
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Inhibition '=' 31 %
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Inhibition '=' 63 %
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Emax '=' 24 %
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00402 Opium poppy Papaver somniferum Herbs and Spices
BXGF00862 Phebalium ozothamnoides Phebalium ozothamnoides Others
BXGF00883 Chrozophora prostrata Chrozophora prostrata Medicinal Plant
BXGF00977 Vitex megapotamica Vitex megapotamica Human Edible Plant
BXGF01266 Dysoxylum lenticellatum Dysoxylum lenticellatum Others
BXGF01284 Saururus cernuus Saururus cernuus Medicinal Plant
BXGF01343 Strychnos fendleri Strychnos fendleri Others
BXGF01466 Halimeda macroloba Halimeda macroloba Others
BXGF01510 Cabucala madagascariensis Cabucala madagascariensis Others
BXGF02723 Hesperocyparis macrocarpa Hesperocyparis macrocarpa Others
BXGF02848 Buxus sempervirens Buxus sempervirens Medicinal Plant
BXGF03270 Aruncus dioicus Aruncus dioicus Medicinal Plant
BXGF03442 Rhaponticum carthamoides Rhaponticum carthamoides Medicinal Plant
BXGF03870 Aloe microstigma Aloe microstigma Others
BXGF03924 Kochia trichophylla Kochia trichophylla Others
BXGF04191 Vicia villosa Vicia villosa Medicinal Plant
BXGF04830 Artemisia oranensis Artemisia oranensis Others
BXGF05193 Piper futokadsura Piper futokadsura Others
BXGF05692 Potentilla multifida Potentilla multifida Medicinal Plant
BXGF05859 Haplopappus venetus Haplopappus venetus Others
BXGF05925 Centaurea amara Centaurea amara Others
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease