Showing entry for Tangeritin


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0001733
Compound NameTangeritin
Structure
FormulaC20H20O7
InchiKeyULSUXBXHSYSGDT-UHFFFAOYSA-N
SMILESCOC1=CC=C(C=C1)C1=CC(=O)C2=C(OC)C(OC)=C(OC)C(OC)=C2O1
InchiInChI=1S/C20H20O7/c1-22-12-8-6-11(7-9-12)14-10-13(21)15-16(23-2)18(24-3)20(26-5)19(25-4)17(15)27-14/h6-10H,1-5H3
IUPAC5,6,7,8-tetramethoxy-2-(4-methoxyphenyl)-4H-chromen-4-one
Molecular Weight372.37
Pubchem Id68077
Chembl IdCHEMBL73930
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB 50209218
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT021792 ATP-binding cassette sub-family G member 2 reviewed Transporter ABCG2 - 17000 - -
reviewed BXGT009618 Delta-type opioid receptor reviewed Oprd1 7000 - - -
reviewed BXGT010343 Mu-type opioid receptor reviewed Oprm1 16300 - - -
reviewed BXGT021792 ATP-binding cassette sub-family G member 2 reviewed Transporter ABCG2 - 19000 - -
reviewed BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 - 39000 - -
reviewed BXGT010602 Xanthine dehydrogenase/oxidase reviewed Enzyme XDH - >100000 - -
CHEMBL CHEMBL73930
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
Q9UNQ0 BXGT021792 ATP-binding cassette sub-family G member 2 reviewed Transporter ABCG2 IC50 '=' 19000 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 IC50 '=' 39000 nM
O94956 BXGT005343 Solute carrier organic anion transporter family member 2B1 reviewed Transporter SLCO2B1 Activity '=' 89 %
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 Potency '=' 12589 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 16360 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 14581 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Activity '=' 175 %
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Activity - - -
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Inhibition - - -
P00352 BXGT005510 Retinal dehydrogenase 1 reviewed Enzyme ALDH1A1 Potency '=' 1412 nM
P47989 BXGT010602 Xanthine dehydrogenase/oxidase reviewed Enzyme XDH IC50 '>' 100000 nM
A0A0C5K5S3 BXGT000138 Fluoroquinolone resistance protein unreviewed - mdeA FC '=' 2 -
P42866 BXGT010343 Mu-type opioid receptor reviewed - Oprm1 Ki '=' 16300 nM
O94782 BXGT005332 Ubiquitin carboxyl-terminal hydrolase 1 reviewed Enzyme USP1 Potency - 89125 nM
Q9UNQ0 BXGT021792 ATP-binding cassette sub-family G member 2 reviewed Transporter ABCG2 IC50 '=' 17000 nM
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A reviewed - KMT2A Potency '=' 10000 nM
O00255 BXGT003903 Menin reviewed - MEN1 Potency '=' 10000 nM
Q9Y6L6 BXGT022334 Solute carrier organic anion transporter family member 1B1 reviewed Transporter SLCO1B1 Inhibition '=' 494 %
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 IC50 - - -
P83916 BXGT012025 Chromobox protein homolog 1 reviewed Epigenetic regulator CBX1 Potency - 63095 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 20596 nM
P10828 BXGT007624 Thyroid hormone receptor beta reviewed Nuclear receptor THRB Potency '=' 0 nM
O94956 BXGT005343 Solute carrier organic anion transporter family member 2B1 reviewed Transporter SLCO2B1 Activity '=' 25 %
A0A0C5K5S3 BXGT000138 Fluoroquinolone resistance protein unreviewed - mdeA MIC '=' 128 ug.mL-1
P0A0J7 BXGT006970 Quinolone resistance protein NorA reviewed - norA FC '=' 2 -
P32300 BXGT009618 Delta-type opioid receptor reviewed - Oprd1 Ki '=' 7000 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 23109 nM
Q8WZA2 BXGT019025 Rap guanine nucleotide exchange factor 4 reviewed Enzyme modulator RAPGEF4 Potency - 31622 nM
Q13148 BXGT013318 TAR DNA-binding protein 43 reviewed - TARDBP Potency - 3981 nM
Q9NPD5 BXGT021151 Solute carrier organic anion transporter family member 1B3 reviewed Transporter SLCO1B3 Inhibition '=' 175 %
P14916 BXGT008066 Urease subunit alpha reviewed - ureA IC50 '=' 4628000 nM
P69996 BXGT011656 Urease subunit beta reviewed - ureB IC50 '=' 4628000 nM
P0A0J7 BXGT006970 Quinolone resistance protein NorA reviewed - norA MIC '=' 4 ug.mL-1
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00054 Lemon Citrus limon Fruits
BXGF00055 Pummelo Citrus maxima Fruits
BXGF00056 Mandarin orange (Clementine, Tangerine) Citrus reticulata Fruits
BXGF00057 Sweet orange Citrus sinensis Fruits
BXGF00097 Sweet bay Laurus nobilis Herbs and Spices
BXGF00165 Common sage Salvia officinalis Herbs and Spices
BXGF00811 Citrus Fruits
BXGF00823 Fruits Fruits
BXGF00871 Citrus unshiu Citrus unshiu Medicinal Plant
BXGF01325 Murraya exotica Murraya exotica Medicinal Plant
BXGF01966 Chromolaena odorata Chromolaena odorata Medicinal Plant
BXGF02106 Citrus medica Citrus medica Medicinal Plant
BXGF02237 Citrus wilsonii Citrus wilsonii Medicinal Plant
BXGF02592 Ilex affinis Ilex affinis Human Edible Plant
BXGF02667 Anaxagorea clavata Anaxagorea clavata Others
BXGF03144 Stenostomum lucidum Stenostomum lucidum Others
BXGF03147 Beyeria brevifolia Beyeria brevifolia Others
BXGF03256 Platycodon grandiflorus Platycodon grandiflorus Medicinal Plant
BXGF03327 Citrus trifoliata Citrus trifoliata Human Edible Plant
BXGF03421 Kaempferia pulchra Kaempferia pulchra Medicinal Plant
BXGF03534 Drosera peltata Drosera peltata Medicinal Plant
BXGF03712 Arnica nevadensis Arnica nevadensis Others
BXGF03745 Odixia angusta Odixia angusta Others
BXGF03760 Prunus laurocerasus Prunus laurocerasus Medicinal Plant
BXGF03812 Ficus formosana Ficus formosana Human Edible Plant
BXGF03843 Dipterocarpus alatus Dipterocarpus alatus Medicinal Plant
BXGF03864 Echinops amplexicaulis Echinops amplexicaulis Medicinal Plant
BXGF03873 Quercus aegilops Quercus aegilops Medicinal Plant
BXGF03883 Chloranthus tianmushanensis Chloranthus tianmushanensis Others
BXGF03897 Prosopis glandulosa Prosopis glandulosa Human Edible Plant
BXGF03916 Aria pallescens Aria pallescens Others
BXGF03926 Simira eliezeriana Simira eliezeriana Others
BXGF03939 Senecio squalidus Senecio squalidus Medicinal Plant
BXGF03951 Araujia sericifera Araujia sericifera Medicinal Plant
BXGF03966 Artemisia monogyna Artemisia monogyna Others
BXGF03986 Epaltes gariepina Epaltes gariepina Others
BXGF03991 Seriphidium cinum Seriphidium cinum Medicinal Plant
BXGF04002 Dendrosenecio kilimanjari Dendrosenecio kilimanjari Others
BXGF04009 Isodon kameba Isodon kameba Medicinal Plant
BXGF04016 Pterocarpus grandiflorus Pterocarpus grandiflorus Others
BXGF04030 Chromolaena pulchella Chromolaena pulchella Others
BXGF04041 Bursaria spinosa Bursaria spinosa Human Edible Plant
BXGF04054 Taxodium mucronatum Taxodium mucronatum Medicinal Plant
BXGF04066 Gardenia fosbergii Gardenia fosbergii Others
BXGF04073 Vitex madiensis Vitex madiensis Medicinal Plant
BXGF04144 Agnorhiza bolanderi Agnorhiza bolanderi Others
BXGF04382 Murraya paniculata Murraya paniculata Medicinal Plant
BXGF04452 Citrus japonica Citrus japonica Medicinal Plant
BXGF04708 Sesbania punicea Sesbania punicea Others
BXGF04712 Prunus mume Prunus mume Medicinal Plant
BXGF04958 Gnaphalium affine Gnaphalium affine Medicinal Plant
BXGF05431 Citrus natsudaidai Citrus natsudaidai Human Edible Plant
BXGF05704 Securidaca inappendiculata Securidaca inappendiculata Medicinal Plant
BXGF05819 Citrus aurantium Citrus aurantium Medicinal Plant
BXGF05843 Pteris prolifera Pteris prolifera Others
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease