Showing entry for 40S ribosomal protein S28



                       
General Target Information
BXGT IdBXGT011466
Protein Name40S ribosomal protein S28
Uniport IdP62857
GeneRPS28
Gene Id6234
DomainRibosomal_S28e
Pfam PF01200  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
2. Genetic Information Processing 2.2 Translation hsa03010 Ribosome
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0002181 cytoplasmic translation
Biological Process GO:0030490 maturation of SSU-rRNA
Biological Process GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
Biological Process GO:0000028 ribosomal small subunit assembly
Biological Process GO:0042274 ribosomal small subunit biogenesis
Biological Process GO:0042254 ribosome biogenesis
Biological Process GO:0006364 rRNA processing
Biological Process GO:0006614 SRP-dependent cotranslational protein targeting to membrane
Biological Process GO:0006412 translation
Biological Process GO:0006413 translational initiation
Biological Process GO:0019083 viral transcription
molecular function GO:0003723 RNA binding
molecular function GO:0003735 structural constituent of ribosome
cellular component GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane
cellular component GO:0005829 cytosol
cellular component GO:0022627 cytosolic small ribosomal subunit
cellular component GO:0070062 extracellular exosome
cellular component GO:0005654 nucleoplasm
cellular component GO:0042788 polysomal ribosome
cellular component GO:0015935 small ribosomal subunit
Reactome
Pathway Id Pathway Name
R-HSA-1266738 Developmental Biology
R-HSA-1430728 Metabolism
R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression
R-HSA-156842 Eukaryotic Translation Elongation
R-HSA-156902 Peptide chain elongation
R-HSA-1643685 Disease
R-HSA-168255 Influenza Infection
R-HSA-168273 Influenza Viral RNA Transcription and Replication
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane
R-HSA-192823 Viral mRNA Translation
R-HSA-2262752 Cellular responses to stress
R-HSA-2408522 Selenoamino acid metabolism
R-HSA-2408557 Selenocysteine synthesis
R-HSA-376176 Signaling by ROBO receptors
R-HSA-392499 Metabolism of proteins
R-HSA-392499 Metabolism of proteins
R-HSA-422475 Axon guidance
R-HSA-5663205 Infectious disease
R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol
R-HSA-71291 Metabolism of amino acids and derivatives
R-HSA-72312 rRNA processing
R-HSA-72613 Eukaryotic Translation Initiation
R-HSA-72649 Translation initiation complex formation
R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
R-HSA-72689 Formation of a pool of free 40S subunits
R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex
R-HSA-72702 Ribosomal scanning and start codon recognition
R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit
R-HSA-72737 Cap-dependent Translation Initiation
R-HSA-72764 Eukaryotic Translation Termination
R-HSA-72766 Translation
R-HSA-72766 Translation
R-HSA-8868773 rRNA processing in the nucleus and cytosol
R-HSA-8953854 Metabolism of RNA
R-HSA-8953897 Cellular responses to external stimuli
R-HSA-9010553 Regulation of expression of SLITs and ROBOs
R-HSA-927802 Nonsense-Mediated Decay (NMD)
R-HSA-9633012 Response of EIF2AK4 (GCN2) to amino acid deficiency
R-HSA-9675108 Nervous system development
R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001824 BXGD000081 Agranulocytosis Hemic and Lymphatic Diseases
C0002886 BXGD000144 Anemia, Macrocytic Hemic and Lymphatic Diseases
C0003811 BXGD000222 Cardiac Arrhythmia Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0008925 BXGD000575 Cleft Palate Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C0013336 BXGD000815 Dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0015672 BXGD001011 Fatigue Pathological Conditions, Signs and Symptoms
C0018564 BXGD001204 Hand deformities Musculoskeletal Diseases
C0025990 BXGD001884 Micrognathism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Stomatognathic Diseases
C0030232 BXGD002197 Pallor Pathological Conditions, Signs and Symptoms
C0034012 BXGD002449 Delayed Puberty Endocrine System Diseases
C0043094 BXGD003026 Weight Gain Pathological Conditions, Signs and Symptoms
C0085669 BXGD003233 Acute leukemia Pathological Conditions, Signs and Symptoms; Neoplasms
C0149931 BXGD003388 Migraine Disorders Nervous System Diseases
C0152423 BXGD003587 Congenital small ears Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Otorhinolaryngologic Diseases
C0155552 BXGD003801 Hearing Loss, Mixed Conductive-Sensorineural Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0232466 BXGD004543 Feeding difficulties
C0235833 BXGD004775 Congenital diaphragmatic hernia Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0349588 BXGD007933 Short stature
C0376545 BXGD008002 Hematologic Neoplasms Neoplasms; Hemic and Lymphatic Diseases
C0423110 BXGD008471 Downward slant of palpebral fissure
C0431478 BXGD008692 Posteriorly rotated ear
C0476273 BXGD008986 Respiratory distress Pathological Conditions, Signs and Symptoms; Respiratory Tract Diseases
C0557874 BXGD009444 Global developmental delay
C0678230 BXGD009750 Congenital Epicanthus
C0744356 BXGD010094 Abnormality of the genital system Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1260899 BXGD011841 Anemia, Diamond-Blackfan Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C1839739 BXGD014400 Thick lower lip vermilion
C1842876 BXGD014542 Depressed nasal ridge
C1853242 BXGD015322 Midface retrusion
C1853638 BXGD015349 Broad neck
C1854114 BXGD015383 Short nose
C2919142 BXGD017867 Short Stature, CTCAE
C2931245 BXGD017986 Bone Marrow failure syndromes
C2931850 BXGD018078 Aase Smith syndrome 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C4021821 BXGD020806 Abnormality of the urinary system Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C4225411 BXGD022267 DIAMOND-BLACKFAN ANEMIA 15 WITH MANDIBULOFACIAL DYSOSTOSIS
C4228778 BXGD022292 Abnormality of radial ray
C4282407 BXGD022423 Sparse and thin eyebrow
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0051100 dihydroartemisinin 284.16
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein