Showing entry for Olomoucine


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0007052
Compound NameOlomoucine
Structure
FormulaC15H18N6O
InchiKeyGTVPOLSIJWJJNY-UHFFFAOYSA-N
SMILESCN1C=NC2=C1N=C(NCCO)N=C2NCC1=CC=CC=C1
InchiInChI=1S/C15H18N6O/c1-21-10-18-12-13(17-9-11-5-3-2-4-6-11)19-15(16-7-8-22)20-14(12)21/h2-6,10,22H,7-9H2,1H3,(H2,16,17,19,20)
IUPAC2-{[6-(benzylamino)-9-methyl-9H-purin-2-yl]amino}ethan-1-ol
Molecular Weight298.34
Pubchem Id4592
Chembl IdCHEMBL280074
Targets of Information Source
DrugBank DB02116
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
P24941 BXGT009002 Cyclin-dependent kinase 2 reviewed Kinase CDK2 experimental inhibitor
Q00535 BXGT012534 Cyclin-dependent-like kinase 5 reviewed Kinase CDK5 experimental inhibitor
P06493 BXGT006445 Cyclin-dependent kinase 1 reviewed Kinase CDK1 experimental binder
P28482 BXGT009263 Mitogen-activated protein kinase 1 reviewed Kinase MAPK1 experimental -
PDB OLO
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
P24941 BXGT009002 Cyclin-dependent kinase 2 reviewed CDK2 Kinase - - - -
P63086 BXGT011494 Mitogen-activated protein kinase 1 reviewed Mapk1 - - 27000 - -
Binding DB 5718
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT006445 Cyclin-dependent kinase 1 reviewed Kinase CDK1 - 7000 - -
reviewed BXGT009002 Cyclin-dependent kinase 2 reviewed Kinase CDK2 - 7000 - -
reviewed BXGT007750 Cyclin-dependent kinase 4 reviewed Kinase CDK4 - 1000000 - -
reviewed BXGT013534 Cyclin-dependent kinase 5 activator 1 reviewed Enzyme modulator CDK5R1 - 3000 - -
reviewed BXGT009002 Cyclin-dependent kinase 2 reviewed Kinase CDK2 - 1200 - -
reviewed BXGT013634 Mitogen-activated protein kinase 14 reviewed Kinase MAPK14 - >100000 - -
reviewed BXGT011494 Mitogen-activated protein kinase 1 reviewed Mapk1 - 27000 - -
reviewed BXGT006445 Cyclin-dependent kinase 1 reviewed Kinase CDK1 - 6000 - -
reviewed BXGT013534 Cyclin-dependent kinase 5 activator 1 reviewed Enzyme modulator CDK5R1 - 7000 - -
reviewed BXGT008322 cAMP-dependent protein kinase catalytic subunit alpha reviewed Kinase PRKACA - >2000000 - -
reviewed BXGT007750 Cyclin-dependent kinase 4 reviewed Kinase CDK4 - >1000000 - -
reviewed BXGT009176 Mitogen-activated protein kinase 3 reviewed Kinase MAPK3 - 30000 - -
reviewed BXGT009263 Mitogen-activated protein kinase 1 reviewed Kinase MAPK1 - 7000 - -
reviewed BXGT006445 Cyclin-dependent kinase 1 reviewed Kinase CDK1 - 7 - -
reviewed BXGT009002 Cyclin-dependent kinase 2 reviewed Kinase CDK2 - 7079 - -
reviewed BXGT006445 Cyclin-dependent kinase 1 reviewed Kinase CDK1 - 163 - -
reviewed BXGT007750 Cyclin-dependent kinase 4 reviewed Kinase CDK4 - >200 - -
reviewed BXGT009002 Cyclin-dependent kinase 2 reviewed Kinase CDK2 - 7 - -
reviewed BXGT012534 Cyclin-dependent-like kinase 5 reviewed Kinase CDK5 - 3000 - -
reviewed BXGT012533 Cyclin-dependent kinase 6 reviewed Kinase CDK6 - >250000 - -
reviewed BXGT009176 Mitogen-activated protein kinase 3 reviewed Kinase MAPK3 - 25000 - -
reviewed BXGT009002 Cyclin-dependent kinase 2 reviewed Kinase CDK2 - 10000 - -
reviewed BXGT007750 Cyclin-dependent kinase 4 reviewed Kinase CDK4 - >100000 - -
reviewed BXGT012558 Voltage-dependent N-type calcium channel subunit alpha-1B reviewed Ion channel CACNA1B - - - >1000000
CHEMBL CHEMBL280074
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P90584 BXGT012110 MO15-related protein kinase Pfmrk unreviewed - Pfmrk IC50 '>' 1000000 nM
O95067 BXGT005347 G2/mitotic-specific cyclin-B2 reviewed Enzyme modulator CCNB2 IC50 '=' 163000 nM
Q8WWL7 BXGT019000 G2/mitotic-specific cyclin-B3 reviewed Enzyme modulator CCNB3 IC50 '=' 163000 nM
P14635 BXGT008031 G2/mitotic-specific cyclin-B1 reviewed Enzyme modulator CCNB1 IC50 '=' 163000 nM
P06493 BXGT006445 Cyclin-dependent kinase 1 reviewed Kinase CDK1 IC50 '=' 163000 nM
Q00535 BXGT012534 Cyclin-dependent-like kinase 5 reviewed Kinase CDK5 Ki '=' 6309 nM
Q00975 BXGT012558 Voltage-dependent N-type calcium channel subunit alpha-1B reviewed Ion channel CACNA1B EC50 '>' 1000000 nM
Q16566 BXGT013639 Calcium/calmodulin-dependent protein kinase type IV reviewed Kinase CAMK4 Thermal melting change '=' 0 degrees C
Q00534 BXGT012533 Cyclin-dependent kinase 6 reviewed Kinase CDK6 Thermal melting change '=' 0 degrees C
P49761 BXGT010736 Dual specificity protein kinase CLK3 reviewed Kinase CLK3 Thermal melting change '=' 0 degrees C
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 AC50 - - -
Q9Y6M4 BXGT022335 Casein kinase I isoform gamma-3 reviewed Kinase CSNK1G3 Thermal melting change '=' 0 degrees C
Q00536 BXGT012535 Cyclin-dependent kinase 16 reviewed Kinase CDK16 Thermal melting change '=' 0 degrees C
P14635 BXGT008031 G2/mitotic-specific cyclin-B1 reviewed Enzyme modulator CCNB1 GI '=' 50 %
P06493 BXGT006445 Cyclin-dependent kinase 1 reviewed Kinase CDK1 GI '=' 50 %
O96020 BXGT005416 G1/S-specific cyclin-E2 reviewed Enzyme modulator CCNE2 ID50 '=' 7 uM
P24941 BXGT009002 Cyclin-dependent kinase 2 reviewed Kinase CDK2 ID50 '=' 7 uM
P24864 BXGT009000 G1/S-specific cyclin-E1 reviewed Enzyme modulator CCNE1 ID50 '=' 7 uM
P10253 BXGT007550 Lysosomal alpha-glucosidase reviewed Enzyme GAA Potency '=' 14125 nM
P54646 BXGT011062 5'-AMP-activated protein kinase catalytic subunit alpha-2 reviewed Kinase PRKAA2 Thermal melting change '=' 0 degrees C
P23458 BXGT008868 Tyrosine-protein kinase JAK1 reviewed Kinase JAK1 Thermal melting change '=' 0 degrees C
Q13043 BXGT013307 Serine/threonine-protein kinase 4 reviewed Kinase STK4 Thermal melting change '=' 0 degrees C
P24941 BXGT009002 Cyclin-dependent kinase 2 reviewed Kinase CDK2 Ki '=' 3981 nM
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 44668 nM
P90584 BXGT012110 MO15-related protein kinase Pfmrk unreviewed - Pfmrk IC50 '=' 1100000 nM
O96020 BXGT005416 G1/S-specific cyclin-E2 reviewed Enzyme modulator CCNE2 IC50 '=' 7000 nM
P24941 BXGT009002 Cyclin-dependent kinase 2 reviewed Kinase CDK2 IC50 '=' 7000 nM
P24864 BXGT009000 G1/S-specific cyclin-E1 reviewed Enzyme modulator CCNE1 IC50 '=' 7000 nM
O95067 BXGT005347 G2/mitotic-specific cyclin-B2 reviewed Enzyme modulator CCNB2 ID50 '=' 7 uM
Q8WWL7 BXGT019000 G2/mitotic-specific cyclin-B3 reviewed Enzyme modulator CCNB3 ID50 '=' 7 uM
P14635 BXGT008031 G2/mitotic-specific cyclin-B1 reviewed Enzyme modulator CCNB1 ID50 '=' 7 uM
P06493 BXGT006445 Cyclin-dependent kinase 1 reviewed Kinase CDK1 ID50 '=' 7 uM
P27361 BXGT009176 Mitogen-activated protein kinase 3 reviewed Kinase MAPK3 IC50 '=' 25000 nM
P11802 BXGT007750 Cyclin-dependent kinase 4 reviewed Kinase CDK4 IC50 '>' 200000 nM
P24941 BXGT009002 Cyclin-dependent kinase 2 reviewed Kinase CDK2 IC50 '=' 7000 nM
P24385 BXGT008965 G1/S-specific cyclin-D1 reviewed Enzyme modulator CCND1 IC50 '=' 1000000 nM
P11802 BXGT007750 Cyclin-dependent kinase 4 reviewed Kinase CDK4 IC50 '=' 1000000 nM
P00533 BXGT005575 Epidermal growth factor receptor reviewed Kinase EGFR IC50 '=' 440000 nM
P06493 BXGT006445 Cyclin-dependent kinase 1 reviewed Kinase CDK1 IC50 '=' 6000 nM
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 AC50 '=' 5011 nM
Q00535 BXGT012534 Cyclin-dependent-like kinase 5 reviewed Kinase CDK5 IC50 '=' 3000 nM
P14635 BXGT008031 G2/mitotic-specific cyclin-B1 reviewed Enzyme modulator CCNB1 IC50 '=' 7000 nM
P06493 BXGT006445 Cyclin-dependent kinase 1 reviewed Kinase CDK1 IC50 '=' 7000 nM
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 Potency '=' 15848 nM
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 AC50 - - -
P09217 BXGT006872 Protein kinase C zeta type reviewed - Prkcz IC50 '=' 1000000 nM
Q9WTQ0 BXGT021929 Protein kinase C theta type reviewed - Prkcq IC50 '=' 1000000 nM
Q64617 BXGT016127 Protein kinase C eta type reviewed - Prkch IC50 '=' 1000000 nM
P09215 BXGT006870 Protein kinase C delta type reviewed - Prkcd IC50 '=' 1000000 nM
P63319 BXGT011518 Protein kinase C gamma type reviewed - Prkcg IC50 '=' 1000000 nM
P09216 BXGT006871 Protein kinase C epsilon type reviewed - Prkce IC50 '=' 1000000 nM
P68403 BXGT011600 Protein kinase C beta type reviewed - Prkcb IC50 '=' 1000000 nM
P05696 BXGT006379 Protein kinase C alpha type reviewed - Prkca IC50 '=' 1000000 nM
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 AC50 '=' 1258 nM
O95067 BXGT005347 G2/mitotic-specific cyclin-B2 reviewed Enzyme modulator CCNB2 IC50 '=' 7000 nM
Q8WWL7 BXGT019000 G2/mitotic-specific cyclin-B3 reviewed Enzyme modulator CCNB3 IC50 '=' 7000 nM
P30279 BXGT009415 G1/S-specific cyclin-D2 reviewed Enzyme modulator CCND2 IA - - -
P30281 BXGT009416 G1/S-specific cyclin-D3 reviewed Enzyme modulator CCND3 IA - - -
P24385 BXGT008965 G1/S-specific cyclin-D1 reviewed Enzyme modulator CCND1 IA - - -
P11802 BXGT007750 Cyclin-dependent kinase 4 reviewed Kinase CDK4 IA - - -
P00352 BXGT005510 Retinal dehydrogenase 1 reviewed Enzyme ALDH1A1 Potency '=' 44668 nM
P78396 BXGT011842 Cyclin-A1 reviewed Enzyme modulator CCNA1 IC50 '=' 7000 nM
P20248 BXGT008554 Cyclin-A2 reviewed Enzyme modulator CCNA2 IC50 '=' 7000 nM
P06493 BXGT006445 Cyclin-dependent kinase 1 reviewed Kinase CDK1 IC50 '=' 7000 nM
Q86V86 BXGT017617 Serine/threonine-protein kinase pim-3 reviewed - PIM3 Thermal melting change '=' 0 degrees C
P51812 BXGT010893 Ribosomal protein S6 kinase alpha-3 reviewed Kinase RPS6KA3 Thermal melting change '=' 0 degrees C
Q9P289 BXGT021300 Serine/threonine-protein kinase 26 reviewed Kinase STK26 Thermal melting change '=' 0 degrees C
Q9UQM7 BXGT021814 Calcium/calmodulin-dependent protein kinase type II subunit alpha reviewed Kinase CAMK2A Thermal melting change '=' 0 degrees C
Q09013 BXGT013023 Myotonin-protein kinase reviewed Kinase DMPK Thermal melting change '=' 0 degrees C
P53350 BXGT010984 Serine/threonine-protein kinase PLK1 reviewed Kinase PLK1 Thermal melting change '=' 0 degrees C
Q16637 BXGT013646 Survival motor neuron protein reviewed Epigenetic regulator SMN1 Potency '=' 31622 nM
P78396 BXGT011842 Cyclin-A1 reviewed Enzyme modulator CCNA1 Inhibition '=' 43 %
P20248 BXGT008554 Cyclin-A2 reviewed Enzyme modulator CCNA2 Inhibition '=' 43 %
P24941 BXGT009002 Cyclin-dependent kinase 2 reviewed Kinase CDK2 Inhibition '=' 43 %
Q96RR4 BXGT019734 Calcium/calmodulin-dependent protein kinase kinase 2 reviewed Kinase CAMKK2 Thermal melting change '=' 0 degrees C
O96020 BXGT005416 G1/S-specific cyclin-E2 reviewed Enzyme modulator CCNE2 IC50 '=' 10000 nM
P24941 BXGT009002 Cyclin-dependent kinase 2 reviewed Kinase CDK2 IC50 '=' 10000 nM
P24864 BXGT009000 G1/S-specific cyclin-E1 reviewed Enzyme modulator CCNE1 IC50 '=' 10000 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 29855 nM
P24941 BXGT009002 Cyclin-dependent kinase 2 reviewed Kinase CDK2 IC50 '=' 1200 nM
Q00534 BXGT012533 Cyclin-dependent kinase 6 reviewed Kinase CDK6 IC50 '>' 250000 nM
P30281 BXGT009416 G1/S-specific cyclin-D3 reviewed Enzyme modulator CCND3 IC50 '>' 250000 nM
O15530 BXGT004177 3-phosphoinositide-dependent protein kinase 1 reviewed Kinase PDPK1 Thermal melting change '=' 0 degrees C
P24385 BXGT008965 G1/S-specific cyclin-D1 reviewed Enzyme modulator CCND1 IC50 '>' 1000000 nM
P11802 BXGT007750 Cyclin-dependent kinase 4 reviewed Kinase CDK4 IC50 '>' 1000000 nM
P28482 BXGT009263 Mitogen-activated protein kinase 1 reviewed Kinase MAPK1 IC50 '=' 7000 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 50118 nM
P22612 BXGT008785 cAMP-dependent protein kinase catalytic subunit gamma reviewed Kinase PRKACG IC50 '>' 2000000 nM
P17612 BXGT008322 cAMP-dependent protein kinase catalytic subunit alpha reviewed Kinase PRKACA IC50 '>' 2000000 nM
P22694 BXGT008797 cAMP-dependent protein kinase catalytic subunit beta reviewed Kinase PRKACB IC50 '>' 2000000 nM
P16050 BXGT008184 Arachidonate 15-lipoxygenase reviewed Enzyme ALOX15 Potency '=' 15848 nM
P27361 BXGT009176 Mitogen-activated protein kinase 3 reviewed Kinase MAPK3 IC50 '=' 30000 nM
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit reviewed Transcription factor NFKB1 Potency '=' 6309 nM
P06493 BXGT006445 Cyclin-dependent kinase 1 reviewed Kinase CDK1 IC50 '=' 4600 nM
P11802 BXGT007750 Cyclin-dependent kinase 4 reviewed Kinase CDK4 IC50 '>' 100000 nM
P24941 BXGT009002 Cyclin-dependent kinase 2 reviewed Kinase CDK2 GI '=' 51 %
P24864 BXGT009000 G1/S-specific cyclin-E1 reviewed Enzyme modulator CCNE1 GI '=' 51 %
Q8IV63 BXGT018341 Inactive serine/threonine-protein kinase VRK3 reviewed Kinase VRK3 Thermal melting change '=' 0 degrees C
Q13555 BXGT013375 Calcium/calmodulin-dependent protein kinase type II subunit gamma reviewed Kinase CAMK2G Thermal melting change '=' 0 degrees C
P52564 BXGT010932 Dual specificity mitogen-activated protein kinase kinase 6 reviewed Kinase MAP2K6 Thermal melting change '=' 0 degrees C
Q16659 BXGT013652 Mitogen-activated protein kinase 6 reviewed Kinase MAPK6 Thermal melting change '=' 0 degrees C
Q9P286 BXGT021299 Serine/threonine-protein kinase PAK 5 reviewed Kinase PAK5 Thermal melting change '=' 0 degrees C
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 Potency '=' 1258 nM
O96020 BXGT005416 G1/S-specific cyclin-E2 reviewed Enzyme modulator CCNE2 IC50 '=' 5000 nM
P24941 BXGT009002 Cyclin-dependent kinase 2 reviewed Kinase CDK2 IC50 '=' 5000 nM
P24864 BXGT009000 G1/S-specific cyclin-E1 reviewed Enzyme modulator CCNE1 IC50 '=' 5000 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 29092 nM
P14635 BXGT008031 G2/mitotic-specific cyclin-B1 reviewed Enzyme modulator CCNB1 Inhibition '=' 48 %
P06493 BXGT006445 Cyclin-dependent kinase 1 reviewed Kinase CDK1 Inhibition '=' 48 %
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 Potency '=' 3162 nM
Q8IU85 BXGT018333 Calcium/calmodulin-dependent protein kinase type 1D reviewed Kinase CAMK1D Thermal melting change '=' 0 degrees C
O75716 BXGT005147 Serine/threonine-protein kinase 16 reviewed Kinase STK16 Thermal melting change '=' 0 degrees C
Q15759 BXGT013595 Mitogen-activated protein kinase 11 reviewed Kinase MAPK11 Thermal melting change '=' 0 degrees C
Q9BVS4 BXGT020147 Serine/threonine-protein kinase RIO2 reviewed Kinase RIOK2 Thermal melting change '=' 0 degrees C
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency '=' 89 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 26608 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 39810 nM
P36507 BXGT009923 Dual specificity mitogen-activated protein kinase kinase 2 reviewed Kinase MAP2K2 Thermal melting change '=' 0 degrees C
Q9P1W9 BXGT021296 Serine/threonine-protein kinase pim-2 reviewed Kinase PIM2 Thermal melting change '=' 0 degrees C
P51812 BXGT010893 Ribosomal protein S6 kinase alpha-3 reviewed Kinase RPS6KA3 Thermal melting change '=' 0 degrees C
P15917 BXGT008169 Lethal factor reviewed - lef Potency '=' 12589 nM
Q16637 BXGT013646 Survival motor neuron protein reviewed Epigenetic regulator SMN1 Potency '=' 891 nM
P27361 BXGT009176 Mitogen-activated protein kinase 3 reviewed Kinase MAPK3 Thermal melting change '=' 0 degrees C
P51955 BXGT010908 Serine/threonine-protein kinase Nek2 reviewed Kinase NEK2 Thermal melting change '=' 1 degrees C
Q15078 BXGT013534 Cyclin-dependent kinase 5 activator 1 reviewed Enzyme modulator CDK5R1 IC50 '=' 7000 nM
Q00535 BXGT012534 Cyclin-dependent-like kinase 5 reviewed Kinase CDK5 IC50 '=' 7000 nM
B2RXH2 BXGT002006 Lysine-specific demethylase 4E reviewed - KDM4E Potency '=' 25118 nM
Q9HC98 BXGT020528 Serine/threonine-protein kinase Nek6 reviewed Kinase NEK6 Thermal melting change '=' 0 degrees C
P21728 BXGT008686 D(1A) dopamine receptor reviewed G-protein coupled receptor DRD1 Potency - 3 nM
Q00532 BXGT012532 Cyclin-dependent kinase-like 1 reviewed Kinase CDKL1 Thermal melting change '=' 0 degrees C
Q99986 BXGT019980 Serine/threonine-protein kinase VRK1 reviewed Kinase VRK1 Thermal melting change '=' 0 degrees C
Q96NX5 BXGT019702 Calcium/calmodulin-dependent protein kinase type 1G reviewed Kinase CAMK1G Thermal melting change '=' 0 degrees C
O43293 BXGT004584 Death-associated protein kinase 3 reviewed Kinase DAPK3 Thermal melting change '=' 0 degrees C
P49841 BXGT010750 Glycogen synthase kinase-3 beta reviewed Kinase GSK3B Thermal melting change '=' 0 degrees C
Q13554 BXGT013374 Calcium/calmodulin-dependent protein kinase type II subunit beta reviewed Kinase CAMK2B Thermal melting change '=' 0 degrees C
Q9UKE5 BXGT021741 TRAF2 and NCK-interacting protein kinase reviewed Kinase TNIK Thermal melting change '=' 0 degrees C
O96013 BXGT005414 Serine/threonine-protein kinase PAK 4 reviewed Kinase PAK4 Thermal melting change '=' 0 degrees C
Q15208 BXGT013550 Serine/threonine-protein kinase 38 reviewed Kinase STK38 Thermal melting change '=' 0 degrees C
Q9HCP0 BXGT020536 Casein kinase I isoform gamma-1 reviewed Kinase CSNK1G1 Thermal melting change '=' 0 degrees C
P78368 BXGT011840 Casein kinase I isoform gamma-2 reviewed Kinase CSNK1G2 Thermal melting change '=' 0 degrees C
Q9H2G2 BXGT020452 STE20-like serine/threonine-protein kinase reviewed Kinase SLK Thermal melting change '=' 0 degrees C
P15289 BXGT008102 Arylsulfatase A reviewed Enzyme ARSA Potency - 5358 nM
P11309 BXGT007685 Serine/threonine-protein kinase pim-1 reviewed Kinase PIM1 Thermal melting change '=' -1 degrees C
P17612 BXGT008322 cAMP-dependent protein kinase catalytic subunit alpha reviewed Kinase PRKACA Thermal melting change '=' 0 degrees C
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 AC50 '=' 15848 nM
Q16637 BXGT013646 Survival motor neuron protein reviewed Epigenetic regulator SMN1 Potency '=' 25118 nM
Q13557 BXGT013376 Calcium/calmodulin-dependent protein kinase type II subunit delta reviewed Kinase CAMK2D Thermal melting change '=' 0 degrees C
P49759 BXGT010734 Dual specificity protein kinase CLK1 reviewed Kinase CLK1 Thermal melting change '=' 0 degrees C
P49760 BXGT010735 Dual specificity protein kinase CLK2 reviewed Kinase CLK2 Thermal melting change '=' 0 degrees C
Q9NQU5 BXGT021169 Serine/threonine-protein kinase PAK 6 reviewed - PAK6 Thermal melting change '=' 0 degrees C
O95747 BXGT005393 Serine/threonine-protein kinase OSR1 reviewed Kinase OXSR1 Thermal melting change '=' 0 degrees C
Q9UEE5 BXGT021671 Serine/threonine-protein kinase 17A reviewed Kinase STK17A Thermal melting change '=' 0 degrees C
Q99683 BXGT019947 Mitogen-activated protein kinase kinase kinase 5 reviewed Kinase MAP3K5 Thermal melting change '=' 0 degrees C
O94804 BXGT005334 Serine/threonine-protein kinase 10 reviewed Kinase STK10 Thermal melting change '=' 0 degrees C
Q86Y07 BXGT017631 Serine/threonine-protein kinase VRK2 reviewed Kinase VRK2 Thermal melting change '=' 0 degrees C
O00506 BXGT003932 Serine/threonine-protein kinase 25 reviewed Kinase STK25 Thermal melting change '=' 0 degrees C
P78396 BXGT011842 Cyclin-A1 reviewed Enzyme modulator CCNA1 IC50 '=' 10000 nM
P20248 BXGT008554 Cyclin-A2 reviewed Enzyme modulator CCNA2 IC50 '=' 10000 nM
Q9P289 BXGT021300 Serine/threonine-protein kinase 26 reviewed Kinase STK26 Thermal melting change '=' 0 degrees C
O00444 BXGT003921 Serine/threonine-protein kinase PLK4 reviewed Kinase PLK4 Thermal melting change '=' 0 degrees C
P24941 BXGT009002 Cyclin-dependent kinase 2 reviewed Kinase CDK2 Thermal melting change '=' 0 degrees C
O96017 BXGT005415 Serine/threonine-protein kinase Chk2 reviewed Kinase CHEK2 Thermal melting change '=' 0 degrees C
Q96KB5 BXGT019685 Lymphokine-activated killer T-cell-originated protein kinase reviewed Kinase PBK Thermal melting change '=' 0 degrees C
P24941 BXGT009002 Cyclin-dependent kinase 2 reviewed Kinase CDK2 IC50 '=' 7079 nM
P24864 BXGT009000 G1/S-specific cyclin-E1 reviewed Enzyme modulator CCNE1 IC50 '=' 7079 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 18356 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00825 Root vegetables Vegetables
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease