Showing entry for Metabotropic glutamate receptor 8


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT011675
Protein NameMetabotropic glutamate receptor 8
Uniport IdP70579
GeneGrm8
Gene Id60590
Domain7tm_3; ANF_receptor; NCD3G
Pfam PF00003   PF01094   PF07562  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007196 adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway
Biological Process GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
Biological Process GO:0007268 chemical synaptic transmission
Biological Process GO:0050966 detection of mechanical stimulus involved in sensory perception of pain
Biological Process GO:0007216 G protein-coupled glutamate receptor signaling pathway
Biological Process GO:1901214 regulation of neuron death
Biological Process GO:0046928 regulation of neurotransmitter secretion
Biological Process GO:0051966 regulation of synaptic transmission, glutamatergic
Biological Process GO:0019233 sensory perception of pain
Biological Process GO:0035249 synaptic transmission, glutamatergic
molecular function GO:0008066 glutamate receptor activity
molecular function GO:0004930 G protein-coupled receptor activity
molecular function GO:0001642 group III metabotropic glutamate receptor activity
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0043025 neuronal cell body
cellular component GO:0043005 neuron projection
cellular component GO:0045211 postsynaptic membrane
cellular component GO:0042734 presynaptic membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000651 Harmalan 184.24
BXGC0001545 Harmine 212.25
BXGC0006162 L-Glutamic acid 147.13
BXGC0036476 D-Glutamate 147.05
BXGC0039032 Glutamic Acid 145.04
BXGC0052372 (2S,4S)-4-Hydroxyglutamic Acid 163.05
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein