Showing entry for Perilipin-5


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT012560
Protein NamePerilipin-5
Uniport IdQ00G26
GenePLIN5
Gene Id440503
DomainPerilipin
Pfam PF03036  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.2 Endocrine system hsa03320 PPAR signaling pathway
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0034389 lipid droplet organization
Biological Process GO:0019915 lipid storage
Biological Process GO:0051646 mitochondrion localization
Biological Process GO:0031999 negative regulation of fatty acid beta-oxidation
Biological Process GO:0060192 negative regulation of lipase activity
Biological Process GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway
Biological Process GO:2000378 negative regulation of reactive oxygen species metabolic process
Biological Process GO:0010897 negative regulation of triglyceride catabolic process
Biological Process GO:0032000 positive regulation of fatty acid beta-oxidation
Biological Process GO:0060193 positive regulation of lipase activity
Biological Process GO:0010884 positive regulation of lipid storage
Biological Process GO:0010890 positive regulation of sequestering of triglyceride
Biological Process GO:0010867 positive regulation of triglyceride biosynthetic process
molecular function GO:0042802 identical protein binding
molecular function GO:0035473 lipase binding
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0005811 lipid droplet
cellular component GO:0005739 mitochondrion
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0015695 BXGD001013 Fatty Liver Digestive System Diseases
C0018801 BXGD001226 Heart failure Cardiovascular Diseases
C0018802 BXGD001227 Congestive heart failure Cardiovascular Diseases
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0022650 BXGD001568 Kidney Calculi Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0035412 BXGD002548 Rhabdomyosarcoma Neoplasms
C0079731 BXGD003087 B-Cell Lymphomas Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0151744 BXGD003469 Myocardial Ischemia Cardiovascular Diseases
C0220611 BXGD004295 Childhood Rhabdomyosarcoma Neoplasms
C0271650 BXGD006227 Impaired glucose tolerance Nutritional and Metabolic Diseases
C0279550 BXGD006635 Adult Rhabdomyosarcoma Neoplasms
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0392525 BXGD008052 Nephrolithiasis Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0400966 BXGD008266 Non-alcoholic Fatty Liver Disease Digestive System Diseases
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C4529962 BXGD023178 Fatty Liver Disease
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0005982 Curcumin 368.38
BXGC0006198 Citric acid 192.12
BXGC0015879 Chlorhexidine 504.2
BXGC0024810 curcumin 368.13
BXGC0024988 Nifedipine 346.12
BXGC0025020 Methyl (2R)-2-Amino-3-Sulfanylpropanoate 135.04
BXGC0033999 Zuclomiphene 405.19
BXGC0037718 Ethacrynic Acid 302.01
BXGC0044200 Menadione 172.05
BXGC0046510 Tpck 351.07
BXGC0049858 Chalcone 208.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein