Showing entry for Polypeptide N-acetylgalactosaminyltransferase 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013201
Protein NamePolypeptide N-acetylgalactosaminyltransferase 2
Uniport IdQ10471
GeneGALNT2
Gene Id2590
DomainGlycos_transf_2; Ricin_B_lectin
Pfam PF00535   PF00652  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.7 Glycan biosynthesis and metabolism hsa00512 Mucin type O-glycan biosynthesis
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0002378 immunoglobulin biosynthetic process
Biological Process GO:0016266 O-glycan processing
Biological Process GO:0006493 protein O-linked glycosylation
Biological Process GO:0018242 protein O-linked glycosylation via serine
Biological Process GO:0018243 protein O-linked glycosylation via threonine
molecular function GO:0030246 carbohydrate binding
molecular function GO:0030145 manganese ion binding
molecular function GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0005576 extracellular region
cellular component GO:0005794 Golgi apparatus
cellular component GO:0032580 Golgi cisterna membrane
cellular component GO:0000139 Golgi membrane
cellular component GO:0005795 Golgi stack
cellular component GO:0030173 integral component of Golgi membrane
cellular component GO:0016020 membrane
cellular component GO:0048471 perinuclear region of cytoplasm
Reactome
Pathway Id Pathway Name
R-HSA-199991 Membrane Trafficking
R-HSA-392499 Metabolism of proteins
R-HSA-5173105 O-linked glycosylation
R-HSA-5653656 Vesicle-mediated transport
R-HSA-597592 Post-translational protein modification
R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic
R-HSA-6811442 Intra-Golgi and retrograde Golgi-to-ER traffic
R-HSA-8856688 Golgi-to-ER retrograde transport
R-HSA-913709 O-linked glycosylation of mucins
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001948 BXGD000091 Alcohol consumption Behavior and Behavior Mechanisms
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007134 BXGD000443 Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0007137 BXGD000445 Squamous cell carcinoma Neoplasms
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0017638 BXGD001132 Glioma Neoplasms
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0020473 BXGD001396 Hyperlipidemia Nutritional and Metabolic Diseases
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0020557 BXGD001432 Hypertriglyceridemia Nutritional and Metabolic Diseases
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0032181 BXGD002332 Platelet Count measurement
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0039483 BXGD002813 Giant Cell Arteritis Skin and Connective Tissue Diseases; Immune System Diseases; Nervous System Diseases; Cardiovascular Diseases
C0202236 BXGD004086 Triglycerides measurement
C0242339 BXGD005150 Dyslipidemias Nutritional and Metabolic Diseases
C0278701 BXGD006566 Gastric Adenocarcinoma Digestive System Diseases; Neoplasms
C0337428 BXGD007155 Fibrinogen assay
C0342883 BXGD007574 Cholesteryl Ester Transfer Protein Deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0392885 BXGD008071 High density lipoprotein measurement
C0410529 BXGD008431 Hypochondroplasia (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0427460 BXGD008616 Red cell distribution width determination
C0428472 BXGD008630 Serum HDL cholesterol measurement
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C0555198 BXGD009432 Malignant Glioma Neoplasms
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1281901 BXGD012133 Fatty acid measurement
C1304746 BXGD012343 RDW - Red blood cell distribution width result
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1611184 BXGD013455 Calcification of coronary artery Nutritional and Metabolic Diseases; Cardiovascular Diseases
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2985280 BXGD018223 Blood Protein Measurement
C3839280 BXGD019772 High grade serous carcinoma
C4524040 BXGD023086 Atherogenic dyslipidaemia
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0003993 Uridine diphosphate 404.16
BXGC0006635 Luteolin 286.24
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein