Showing entry for CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013217
Protein NameCMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1
Uniport IdQ11201
GeneST3GAL1
Gene Id6482
DomainGlyco_transf_29
Pfam PF00777  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.7 Glycan biosynthesis and metabolism hsa00512 Mucin type O-glycan biosynthesis
1. Metabolism 1.7 Glycan biosynthesis and metabolism hsa00533 Glycosaminoglycan biosynthesis - keratan sulfate
1. Metabolism 1.7 Glycan biosynthesis and metabolism hsa00603 Glycosphingolipid biosynthesis - globo and isoglobo series
1. Metabolism 1.7 Glycan biosynthesis and metabolism hsa00604 Glycosphingolipid biosynthesis - ganglio series
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006464 cellular protein modification process
Biological Process GO:0018146 keratan sulfate biosynthetic process
Biological Process GO:0006054 N-acetylneuraminate metabolic process
Biological Process GO:0016266 O-glycan processing
Biological Process GO:0006487 protein N-linked glycosylation
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0097503 sialylation
molecular function GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity
cellular component GO:0070062 extracellular exosome
cellular component GO:0032580 Golgi cisterna membrane
cellular component GO:0000139 Golgi membrane
cellular component GO:0016021 integral component of membrane
cellular component GO:0016020 membrane
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-1630316 Glycosaminoglycan metabolism
R-HSA-1638074 Keratan sulfate/keratin metabolism
R-HSA-1643685 Disease
R-HSA-1643685 Disease
R-HSA-2022854 Keratan sulfate biosynthesis
R-HSA-392499 Metabolism of proteins
R-HSA-4085001 Sialic acid metabolism
R-HSA-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
R-HSA-446203 Asparagine N-linked glycosylation
R-HSA-446219 Synthesis of substrates in N-glycan biosythesis
R-HSA-5173105 O-linked glycosylation
R-HSA-5663205 Infectious disease
R-HSA-5663205 Infectious disease
R-HSA-597592 Post-translational protein modification
R-HSA-71387 Metabolism of carbohydrates
R-HSA-913709 O-linked glycosylation of mucins
R-HSA-9678108 SARS-CoV-1 Infection
R-HSA-9679506 SARS-CoV Infections
R-HSA-9679506 SARS-CoV Infections
R-HSA-9683673 Maturation of protein 3a
R-HSA-9683701 Translation of structural proteins
R-HSA-9694516 SARS-CoV-2 Infection
R-HSA-9694516 SARS-CoV-2 Infection
R-HSA-9694548 Maturation of spike protein
R-HSA-9694635 Translation of structural proteins
R-HSA-9694635 Translation of structural proteins
R-HSA-9694719 Maturation of protein 3a
R-HSA-977068 Termination of O-glycan biosynthesis
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0014378 BXGD000912 Enterovirus Infections Infections
C0018213 BXGD001187 Graves Disease Eye Diseases; Immune System Diseases; Endocrine System Diseases
C0023473 BXGD001661 Myeloid Leukemia, Chronic Neoplasms; Hemic and Lymphatic Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0033975 BXGD002447 Psychotic Disorders Mental Disorders
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036421 BXGD002613 Systemic Scleroderma Skin and Connective Tissue Diseases
C0086651 BXGD003302 Mucopolysaccharidosis, MPS-IV-A Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0279671 BXGD006677 Cervical Squamous Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0349204 BXGD007892 Nonorganic psychosis Mental Disorders
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0553723 BXGD009416 Squamous cell carcinoma of skin Neoplasms; Skin and Connective Tissue Diseases
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0677886 BXGD009734 Epithelial ovarian cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1274700 BXGD012040 Postmenopausal frontal fibrosing alopecia
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1328504 BXGD012469 Hormone refractory prostate cancer Neoplasms; Male Urogenital Diseases
C1335177 BXGD012771 Ovarian Serous Adenocarcinoma Neoplasms
C1512981 BXGD013196 Mammary Tumorigenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C2062441 BXGD016897 Influenza A
C2216702 BXGD016951 malignant neoplasm of breast staging Neoplasms; Skin and Connective Tissue Diseases
C2938924 BXGD018167 Oestrogen receptor positive breast cancer
C2985280 BXGD018223 Blood Protein Measurement
C4087504 BXGD022156 Peritoneal dissemination
C4255374 BXGD022314 Frontal fibrosing alopecia
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000368 Gallic acid 170.12
BXGC0033310 Epigalocatechin Gallate 458.08
BXGC0037407 Lithocholic Acid 376.3
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein