Showing entry for Hormone refractory prostate cancer


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD012469
Disease NameHormone refractory prostate cancer
Disease CUI IdC1328504
MeSH Codes C04   C12  
Disease Class NameNeoplasms; Male Urogenital Diseases
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00141 BXGT003882 Serine/threonine-protein kinase Sgk1 6446 reviewed Kinase
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O00482 BXGT003929 Nuclear receptor subfamily 5 group A member 2 2494 reviewed Nuclear receptor
O00625 BXGT003941 Pirin 8544 reviewed Transcription factor
O14646 BXGT004079 Chromodomain-helicase-DNA-binding protein 1 1105 reviewed
O14733 BXGT004087 Dual specificity mitogen-activated protein kinase kinase 7 5609 reviewed Kinase
O14770 BXGT004095 Homeobox protein Meis2 4212 reviewed Enzyme
O14788 BXGT004100 Tumor necrosis factor ligand superfamily member 11 8600 reviewed Signaling
O14965 BXGT004117 Aurora kinase A 6790 reviewed Kinase
O14976 BXGT004118 Cyclin-G-associated kinase 2580 reviewed Kinase
O14980 BXGT004119 Exportin-1 7514 reviewed Receptor
O15054 BXGT004121 Lysine-specific demethylase 6B 23135 reviewed Epigenetic regulator
O15111 BXGT004126 Inhibitor of nuclear factor kappa-B kinase subunit alpha 1147 reviewed Kinase
O15164 BXGT004133 Transcription intermediary factor 1-alpha 8805 reviewed
O15197 BXGT004136 Ephrin type-B receptor 6 2051 reviewed Kinase
O15245 BXGT004141 Solute carrier family 22 member 1 6580 reviewed Transporter
O15374 BXGT004157 Monocarboxylate transporter 5 9122 reviewed Transporter
O15379 BXGT004159 Histone deacetylase 3 8841 reviewed Epigenetic regulator
O15427 BXGT004167 Monocarboxylate transporter 4 9123 reviewed Transporter
O15439 BXGT004169 Multidrug resistance-associated protein 4 10257 reviewed Transporter
O15496 BXGT004175 Group 10 secretory phospholipase A2 8399 reviewed Enzyme
O15550 BXGT004179 Lysine-specific demethylase 6A 7403 reviewed Epigenetic regulator
O43143 BXGT004571 Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 1665 reviewed Enzyme
O43157 BXGT004572 Plexin-B1 5364 reviewed
O43255 BXGT004579 E3 ubiquitin-protein ligase SIAH2 6478 reviewed
O43524 BXGT004599 Forkhead box protein O3 2309 reviewed
O43660 BXGT004609 Pleiotropic regulator 1 5356 reviewed
O43791 BXGT004626 Speckle-type POZ protein 8405 reviewed
O60260 BXGT004864 E3 ubiquitin-protein ligase parkin 5071 reviewed Enzyme
O60341 BXGT004873 Lysine-specific histone demethylase 1A 23028 reviewed Epigenetic regulator
O60674 BXGT004892 Tyrosine-protein kinase JAK2 3717 reviewed Kinase
O60760 BXGT004899 Hematopoietic prostaglandin D synthase 27306 reviewed
O60885 BXGT004906 Bromodomain-containing protein 4 23476 reviewed Epigenetic regulator
O75385 BXGT005121 Serine/threonine-protein kinase ULK1 8408 reviewed Kinase
O75469 BXGT005128 Nuclear receptor subfamily 1 group I member 2 8856 reviewed Nuclear receptor
O75475 BXGT005130 PC4 and SFRS1-interacting protein 11168 reviewed Signaling
O75795 BXGT005152 UDP-glucuronosyltransferase 2B17 7367 reviewed
O76074 BXGT005174 cGMP-specific 3',5'-cyclic phosphodiesterase 8654 reviewed
O94956 BXGT005343 Solute carrier organic anion transporter family member 2B1 11309 reviewed Transporter
O95067 BXGT005347 G2/mitotic-specific cyclin-B2 9133 reviewed Enzyme modulator
O95342 BXGT005373 Bile salt export pump 8647 reviewed Transporter
O95718 BXGT005392 Steroid hormone receptor ERR2 2103 reviewed Nuclear receptor
O95835 BXGT005400 Serine/threonine-protein kinase LATS1 9113 reviewed Kinase
O95865 BXGT005404 N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 23564 reviewed Enzyme
O96020 BXGT005416 G1/S-specific cyclin-E2 9134 reviewed Enzyme modulator
P00338 BXGT005504 L-lactate dehydrogenase A chain 3939 reviewed Enzyme
P00352 BXGT005510 Retinal dehydrogenase 1 216 reviewed Enzyme
P00390 BXGT005526 Glutathione reductase, mitochondrial 2936 reviewed Enzyme
P00491 BXGT005555 Purine nucleoside phosphorylase 4860 reviewed Enzyme
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01106 BXGT005730 Myc proto-oncogene protein 4609 reviewed Transcription factor
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01138 BXGT005738 Beta-nerve growth factor 4803 reviewed Signaling
P01148 BXGT005739 Progonadoliberin-1 2796 reviewed
P01303 BXGT005748 Pro-neuropeptide Y 4852 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P02545 BXGT005889 Prelamin-A/C 4000 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P02818 BXGT005969 Osteocalcin 632 reviewed
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04083 BXGT006147 Annexin A1 301 reviewed
P04150 BXGT006154 Glucocorticoid receptor 2908 reviewed Nuclear receptor
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04792 BXGT006264 Heat shock protein beta-1 3315 reviewed
P05026 BXGT006296 Sodium/potassium-transporting ATPase subunit beta-1 481 reviewed Transporter
P05093 BXGT006313 Steroid 17-alpha-hydroxylase/17,20 lyase 1586 reviewed
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06213 BXGT006425 Insulin receptor 3643 reviewed Kinase
P06493 BXGT006445 Cyclin-dependent kinase 1 983 reviewed Kinase
P06730 BXGT006487 Eukaryotic translation initiation factor 4E 1977 reviewed Nucleic acid binding
P07225 BXGT006572 Vitamin K-dependent protein S 5627 reviewed
P07288 BXGT006591 Prostate-specific antigen 354 reviewed Enzyme
P07333 BXGT006602 Macrophage colony-stimulating factor 1 receptor 1436 reviewed Kinase
P07550 BXGT006636 Beta-2 adrenergic receptor 154 reviewed G-protein coupled receptor
P07602 BXGT006646 Prosaposin 5660 reviewed
P07900 BXGT006696 Heat shock protein HSP 90-alpha 3320 reviewed Chaperone
P08047 BXGT006720 Transcription factor Sp1 6667 reviewed Nucleic acid binding
P08069 BXGT006723 Insulin-like growth factor 1 receptor 3480 reviewed Kinase
P08100 BXGT006725 Rhodopsin 6010 reviewed G-protein coupled receptor
P08133 BXGT006727 Annexin A6 309 reviewed
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08246 BXGT006756 Neutrophil elastase 1991 reviewed Enzyme
P08581 BXGT006794 Hepatocyte growth factor receptor 4233 reviewed Kinase
P08670 BXGT006810 Vimentin 7431 reviewed
P08684 BXGT006812 Cytochrome P450 3A4 1576 reviewed Enzyme
P08842 BXGT006830 Steryl-sulfatase 412 reviewed Enzyme
P08887 BXGT006835 Interleukin-6 receptor subunit alpha 3570 reviewed Signaling
P08922 BXGT006843 Proto-oncogene tyrosine-protein kinase ROS 6098 reviewed Kinase
P09104 BXGT006856 Gamma-enolase 2026 reviewed Enzyme
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P09237 BXGT006874 Matrilysin 4316 reviewed Enzyme
P09382 BXGT006882 Galectin-1 3956 reviewed Signaling
P09429 BXGT006889 High mobility group protein B1 3146 reviewed Nucleic acid binding
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P09651 BXGT006913 Heterogeneous nuclear ribonucleoprotein A1 3178 reviewed
P09874 BXGT006934 Poly [ADP-ribose] polymerase 1 142 reviewed
P0DMV8 BXGT007509 Heat shock 70 kDa protein 1A 3304 reviewed
P0DMV9 BXGT007510 Heat shock 70 kDa protein 1B 3304 reviewed
P10070 BXGT007534 Zinc finger protein GLI2 2736 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10301 BXGT007556 Ras-related protein R-Ras 6237 reviewed Enzyme modulator
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10599 BXGT007583 Thioredoxin 7295 reviewed
P10646 BXGT007598 Tissue factor pathway inhibitor 7035 reviewed Enzyme modulator
P10909 BXGT007630 Clusterin 1191 reviewed
P11021 BXGT007644 Endoplasmic reticulum chaperone BiP 3309 reviewed
P11142 BXGT007658 Heat shock cognate 71 kDa protein 3312 reviewed
P11274 BXGT007681 Breakpoint cluster region protein 613 reviewed Enzyme modulator
P11308 BXGT007684 Transcriptional regulator ERG 2078 reviewed Transcription factor
P11309 BXGT007685 Serine/threonine-protein kinase pim-1 5292 reviewed Kinase
P11362 BXGT007693 Fibroblast growth factor receptor 1 2260 reviewed Kinase
P11474 BXGT007710 Steroid hormone receptor ERR1 2101 reviewed Nuclear receptor
P11511 BXGT007717 Aromatase 1588 reviewed Enzyme
P11802 BXGT007750 Cyclin-dependent kinase 4 1019 reviewed Kinase
P11940 BXGT007762 Polyadenylate-binding protein 1 26986 reviewed
P12931 BXGT007859 Proto-oncogene tyrosine-protein kinase Src 6714 reviewed Kinase
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P14060 BXGT007978 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 3283 reviewed Enzyme
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14555 BXGT008020 Phospholipase A2, membrane associated 5320 reviewed Enzyme
P14618 BXGT008027 Pyruvate kinase PKM 5315 reviewed Kinase
P14672 BXGT008037 Solute carrier family 2, facilitated glucose transporter member 4 6517 reviewed Transporter
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15036 BXGT008073 Protein C-ets-2 2114 reviewed Transcription factor
P15529 BXGT008134 Membrane cofactor protein 4179 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P15907 BXGT008168 Beta-galactoside alpha-2,6-sialyltransferase 1 6480 reviewed
P15941 BXGT008176 Mucin-1 4582 reviewed
P16070 BXGT008186 CD44 antigen 960 reviewed
P16220 BXGT008206 Cyclic AMP-responsive element-binding protein 1 1385 reviewed
P16410 BXGT008224 Cytotoxic T-lymphocyte protein 4 1493 reviewed
P17655 BXGT008325 Calpain-2 catalytic subunit 824 reviewed Enzyme
P17676 BXGT008327 CCAAT/enhancer-binding protein beta 1051 reviewed Transcription factor
P17844 BXGT008346 Probable ATP-dependent RNA helicase DDX5 1655 reviewed
P17936 BXGT008357 Insulin-like growth factor-binding protein 3 3486 reviewed Enzyme modulator
P18074 BXGT008374 General transcription and DNA repair factor IIH helicase subunit XPD 2068 reviewed Enzyme
P18089 BXGT008379 Alpha-2B adrenergic receptor 151 reviewed G-protein coupled receptor
P18146 BXGT008384 Early growth response protein 1 1958 reviewed Nucleic acid binding
P18283 BXGT008395 Glutathione peroxidase 2 2877 reviewed Enzyme
P18405 BXGT008400 3-oxo-5-alpha-steroid 4-dehydrogenase 1 6715 reviewed Enzyme
P18827 BXGT008427 Syndecan-1 6382 reviewed Extracellular structure
P18850 BXGT008433 Cyclic AMP-dependent transcription factor ATF-6 alpha 22926 reviewed
P18887 BXGT008437 DNA repair protein XRCC1 7515 reviewed
P19544 BXGT008494 Wilms tumor protein 7490 reviewed Nucleic acid binding
P20248 BXGT008554 Cyclin-A2 890 reviewed Enzyme modulator
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 1131 reviewed G-protein coupled receptor
P20701 BXGT008591 Integrin alpha-L 3683 reviewed
P20807 BXGT008601 Calpain-3 825 reviewed Enzyme
P20813 BXGT008603 Cytochrome P450 2B6 1555 reviewed
P21266 BXGT008632 Glutathione S-transferase Mu 3 2947 reviewed
P21333 BXGT008638 Filamin-A 2316 reviewed
P21397 BXGT008644 Amine oxidase [flavin-containing] A 4128 reviewed
P21802 BXGT008691 Fibroblast growth factor receptor 2 2263 reviewed Kinase
P21860 BXGT008698 Receptor tyrosine-protein kinase erbB-3 2065 reviewed Kinase
P22004 BXGT008718 Bone morphogenetic protein 6 654 reviewed Signaling
P23246 BXGT008840 Splicing factor, proline- and glutamine-rich 6421 reviewed Nucleic acid binding
P23458 BXGT008868 Tyrosine-protein kinase JAK1 3716 reviewed Kinase
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P24666 BXGT008986 Low molecular weight phosphotyrosine protein phosphatase 52 reviewed
P24928 BXGT009001 DNA-directed RNA polymerase II subunit RPB1 5430 reviewed Enzyme
P25101 BXGT009018 Endothelin-1 receptor 1909 reviewed G-protein coupled receptor
P25440 BXGT009044 Bromodomain-containing protein 2 6046 reviewed Epigenetic regulator
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 1786 reviewed Epigenetic regulator
P27361 BXGT009176 Mitogen-activated protein kinase 3 5595 reviewed Kinase
P27487 BXGT009187 Dipeptidyl peptidase 4 1803 reviewed Enzyme
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P30291 BXGT009417 Wee1-like protein kinase 7465 reviewed Kinase
P31213 BXGT009515 3-oxo-5-alpha-steroid 4-dehydrogenase 2 6716 reviewed Enzyme
P31260 BXGT009519 Homeobox protein Hox-A10 3206 reviewed
P31323 BXGT009521 cAMP-dependent protein kinase type II-beta regulatory subunit 5577 reviewed
P31391 BXGT009535 Somatostatin receptor type 4 6754 reviewed G-protein coupled receptor
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P32119 BXGT009600 Peroxiredoxin-2 7001 reviewed Enzyme
P32322 BXGT009624 Pyrroline-5-carboxylate reductase 1, mitochondrial 5831 reviewed
P34932 BXGT009772 Heat shock 70 kDa protein 4 3308 reviewed
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35348 BXGT009814 Alpha-1A adrenergic receptor 148 reviewed G-protein coupled receptor
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35610 BXGT009855 Sterol O-acyltransferase 1 6646 reviewed Enzyme
P35613 BXGT009856 Basigin 682 reviewed
P35869 BXGT009877 Aryl hydrocarbon receptor 196 reviewed Transcription factor
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P36956 BXGT009947 Sterol regulatory element-binding protein 1 6720 reviewed
P37058 BXGT009956 Testosterone 17-beta-dehydrogenase 3 3293 reviewed
P37059 BXGT009957 Estradiol 17-beta-dehydrogenase 2 3294 reviewed Enzyme
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P37288 BXGT009977 Vasopressin V1a receptor 552 reviewed G-protein coupled receptor
P38398 BXGT010037 Breast cancer type 1 susceptibility protein 672 reviewed Enzyme
P38936 BXGT010074 Cyclin-dependent kinase inhibitor 1 1026 reviewed
P39900 BXGT010148 Macrophage metalloelastase 4321 reviewed Enzyme
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41212 BXGT010235 Transcription factor ETV6 2120 reviewed Transcription factor
P41240 BXGT010242 Tyrosine-protein kinase CSK 1445 reviewed Kinase
P41273 BXGT010251 Tumor necrosis factor ligand superfamily member 9 8744 reviewed
P41279 BXGT010254 Mitogen-activated protein kinase kinase kinase 8 1326 reviewed Kinase
P41595 BXGT010267 5-hydroxytryptamine receptor 2B 3357 reviewed G-protein coupled receptor
P41597 BXGT010268 C-C chemokine receptor type 2 729230 reviewed
P42330 BXGT010301 Aldo-keto reductase family 1 member C3 8644 reviewed Enzyme
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P42684 BXGT010331 Tyrosine-protein kinase ABL2 27 reviewed Kinase
P43235 BXGT010368 Cathepsin K 1513 reviewed Enzyme
P43354 BXGT010381 Nuclear receptor subfamily 4 group A member 2 4929 reviewed Nuclear receptor
P45983 BXGT010494 Mitogen-activated protein kinase 8 5599 reviewed Kinase
P45985 BXGT010496 Dual specificity mitogen-activated protein kinase kinase 4 6416 reviewed Kinase
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P46937 BXGT010554 Transcriptional coactivator YAP1 10413 reviewed Enzyme modulator
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49023 BXGT010672 Paxillin 5829 reviewed Cellular structure
P49116 BXGT010678 Nuclear receptor subfamily 2 group C member 2 7182 reviewed Nuclear receptor
P49841 BXGT010750 Glycogen synthase kinase-3 beta 2932 reviewed Kinase
P50416 BXGT010797 Carnitine O-palmitoyltransferase 1, liver isoform 1374 reviewed Enzyme
P50613 BXGT010815 Cyclin-dependent kinase 7 1022 reviewed Kinase
P50750 BXGT010818 Cyclin-dependent kinase 9 1025 reviewed Kinase
P51679 BXGT010877 C-C chemokine receptor type 4 1233 reviewed G-protein coupled receptor
P51692 BXGT010885 Signal transducer and activator of transcription 5B 6777 reviewed Nucleic acid binding
P51812 BXGT010893 Ribosomal protein S6 kinase alpha-3 6197 reviewed Kinase
P51813 BXGT010894 Cytoplasmic tyrosine-protein kinase BMX 660 reviewed Kinase
P52292 BXGT010925 Importin subunit alpha-1 3838 reviewed Transporter
P52789 BXGT010954 Hexokinase-2 3099 reviewed Kinase
P53350 BXGT010984 Serine/threonine-protein kinase PLK1 5347 reviewed Kinase
P53671 BXGT011009 LIM domain kinase 2 3985 reviewed Kinase
P54646 BXGT011062 5'-AMP-activated protein kinase catalytic subunit alpha-2 5563 reviewed Kinase
P54855 BXGT011088 UDP-glucuronosyltransferase 2B15 7366 reviewed
P55786 BXGT011125 Puromycin-sensitive aminopeptidase 9520 reviewed Enzyme
P55957 BXGT011137 BH3-interacting domain death agonist 637 reviewed
P56470 BXGT011173 Galectin-4 3960 reviewed Signaling
P56937 BXGT011205 3-keto-steroid reductase 51478 reviewed
P58004 BXGT011222 Sestrin-2 83667 reviewed Enzyme
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P60568 BXGT011315 Interleukin-2 3558 reviewed
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P61964 BXGT011396 WD repeat-containing protein 5 11091 reviewed
P61978 BXGT011399 Heterogeneous nuclear ribonucleoprotein K 3190 reviewed Enzyme
P62805 BXGT011457 Histone H4 8370 reviewed
P62820 BXGT011461 Ras-related protein Rab-1A 5861 reviewed
P63104 BXGT011499 14-3-3 protein zeta/delta 7534 reviewed Chaperone
P78358 BXGT011838 Cancer/testis antigen 1 246100 reviewed
P80188 BXGT011882 Neutrophil gelatinase-associated lipocalin 3934 reviewed Enzyme
P80365 BXGT011895 Corticosteroid 11-beta-dehydrogenase isozyme 2 3291 reviewed Enzyme
P98170 BXGT012231 E3 ubiquitin-protein ligase XIAP 331 reviewed Enzyme modulator
Q00535 BXGT012534 Cyclin-dependent-like kinase 5 1020 reviewed Kinase
Q01094 BXGT012568 Transcription factor E2F1 1869 reviewed Nucleic acid binding
Q01105 BXGT012569 Protein SET 6418 reviewed Enzyme modulator
Q01469 BXGT012590 Fatty acid-binding protein 5 2171 reviewed
Q02224 BXGT012643 Centromere-associated protein E 1062 reviewed Cellular structure
Q02790 BXGT012672 Peptidyl-prolyl cis-trans isomerase FKBP4 2288 reviewed Enzyme
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A 4297 reviewed
Q04609 BXGT012768 Glutamate carboxypeptidase 2 2346 reviewed Enzyme
Q04637 BXGT012771 Eukaryotic translation initiation factor 4 gamma 1 1981 reviewed Nucleic acid binding
Q04912 BXGT012790 Macrophage-stimulating protein receptor 4486 reviewed Kinase
Q05329 BXGT012814 Glutamate decarboxylase 2 2572 reviewed Enzyme
Q05397 BXGT012815 Focal adhesion kinase 1 5747 reviewed Kinase
Q05655 BXGT012832 Protein kinase C delta type 5580 reviewed Kinase
Q07075 BXGT012917 Glutamyl aminopeptidase 2028 reviewed Enzyme
Q07812 BXGT012940 Apoptosis regulator BAX 581 reviewed Signaling
Q07820 BXGT012942 Induced myeloid leukemia cell differentiation protein Mcl-1 4170 reviewed Signaling
Q07889 BXGT012946 Son of sevenless homolog 1 6654 reviewed Enzyme modulator
Q07912 BXGT012947 Activated CDC42 kinase 1 10188 reviewed Kinase
Q08050 BXGT012958 Forkhead box protein M1 2305 reviewed
Q09472 BXGT013038 Histone acetyltransferase p300 2033 reviewed
Q09666 BXGT013041 Neuroblast differentiation-associated protein AHNAK 79026 reviewed
Q11201 BXGT013217 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 6482 reviewed
Q12778 BXGT013263 Forkhead box protein O1 2308 reviewed
Q12882 BXGT013276 Dihydropyrimidine dehydrogenase [NADP(+)] 1806 reviewed Enzyme
Q13131 BXGT013314 5'-AMP-activated protein kinase catalytic subunit alpha-1 5562 reviewed Kinase
Q13285 BXGT013335 Steroidogenic factor 1 2516 reviewed Nuclear receptor
Q13304 BXGT013337 Uracil nucleotide/cysteinyl leukotriene receptor 2840 reviewed G-protein coupled receptor
Q13309 BXGT013338 S-phase kinase-associated protein 2 6502 reviewed
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q13393 BXGT013346 Phospholipase D1 5337 reviewed
Q13451 BXGT013356 Peptidyl-prolyl cis-trans isomerase FKBP5 2289 reviewed Enzyme
Q13541 BXGT013371 Eukaryotic translation initiation factor 4E-binding protein 1 1978 reviewed Nucleic acid binding
Q13547 BXGT013373 Histone deacetylase 1 3065 reviewed Epigenetic regulator
Q13639 BXGT013389 5-hydroxytryptamine receptor 4 3360 reviewed G-protein coupled receptor
Q13887 BXGT013401 Krueppel-like factor 5 688 reviewed Nucleic acid binding
Q14289 BXGT013459 Protein-tyrosine kinase 2-beta 2185 reviewed Kinase
Q14457 BXGT013472 Beclin-1 8678 reviewed Enzyme modulator
Q14498 BXGT013475 RNA-binding protein 39 9584 reviewed
Q14683 BXGT013500 Structural maintenance of chromosomes protein 1A 8243 reviewed
Q14790 BXGT013505 Caspase-8 841 reviewed Enzyme
Q15078 BXGT013534 Cyclin-dependent kinase 5 activator 1 8851 reviewed Enzyme modulator
Q15109 BXGT013537 Advanced glycosylation end product-specific receptor 177 reviewed Receptor
Q15185 BXGT013549 Prostaglandin E synthase 3 10728 reviewed Chaperone
Q15233 BXGT013552 Non-POU domain-containing octamer-binding protein 4841 reviewed Nucleic acid binding
Q15257 BXGT013554 Serine/threonine-protein phosphatase 2A activator 5524 reviewed Enzyme modulator
Q15303 BXGT013557 Receptor tyrosine-protein kinase erbB-4 2066 reviewed Kinase
Q15349 BXGT013558 Ribosomal protein S6 kinase alpha-2 6196 reviewed Kinase
Q15418 BXGT013569 Ribosomal protein S6 kinase alpha-1 6195 reviewed Kinase
Q15596 BXGT013582 Nuclear receptor coactivator 2 10499 reviewed Enzyme
Q15831 BXGT013604 Serine/threonine-protein kinase STK11 6794 reviewed Kinase
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16678 BXGT013656 Cytochrome P450 1B1 1545 reviewed Enzyme
Q53EL6 BXGT015008 Programmed cell death protein 4 27250 reviewed Nucleic acid binding
Q53EZ4 BXGT015010 Centrosomal protein of 55 kDa 55165 reviewed
Q5VZ30 BXGT015894 Glutamate decarboxylase 2 (Pancreatic islets and brain, 65kDa) 2572 unreviewed
Q6PL18 BXGT016479 ATPase family AAA domain-containing protein 2 29028 reviewed Epigenetic regulator
Q6UWP2 BXGT016567 Dehydrogenase/reductase SDR family member 11 79154 reviewed Enzyme
Q6ZN17 BXGT016631 Protein lin-28 homolog B 389421 reviewed
Q7LBC6 BXGT016998 Lysine-specific demethylase 3B 51780 reviewed Epigenetic regulator
Q7Z2W7 BXGT017248 Transient receptor potential cation channel subfamily M member 8 79054 reviewed Ion channel
Q7Z434 BXGT017252 Mitochondrial antiviral-signaling protein 57506 reviewed
Q8NBS9 BXGT018543 Thioredoxin domain-containing protein 5 81567 reviewed
Q8TCG1 BXGT018797 Protein CIP2A 57650 reviewed
Q92731 BXGT019366 Estrogen receptor beta 2100 reviewed Nuclear receptor
Q92793 BXGT019374 CREB-binding protein 1387 reviewed
Q93009 BXGT019455 Ubiquitin carboxyl-terminal hydrolase 7 7874 reviewed Enzyme
Q969G3 BXGT019607 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 6605 reviewed
Q96BI3 BXGT019623 Gamma-secretase subunit APH-1A 51107 reviewed Enzyme modulator
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96FL8 BXGT019660 Multidrug and toxin extrusion protein 1 55244 reviewed Transporter
Q96JY6 BXGT019684 PDZ and LIM domain protein 2 64236 reviewed Cellular structure
Q96Q83 BXGT019715 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 221120 reviewed
Q96RR4 BXGT019734 Calcium/calmodulin-dependent protein kinase kinase 2 10645 reviewed Kinase
Q99527 BXGT019930 G-protein coupled estrogen receptor 1 2852 reviewed G-protein coupled receptor
Q99829 BXGT019968 Copine-1 8904 reviewed
Q9BWU1 BXGT020156 Cyclin-dependent kinase 19 23097 reviewed Kinase
Q9BZM4 BXGT020200 UL16-binding protein 3 79465 reviewed
Q9H6W3 BXGT020485 Ribosomal oxygenase 1 79697 reviewed
Q9H6Z9 BXGT020488 Egl nine homolog 3 112399 reviewed
Q9H8P0 BXGT020497 Polyprenol reductase 79644 reviewed
Q9HAS3 BXGT020507 Solute carrier family 28 member 3 64078 reviewed Transporter
Q9NPD5 BXGT021151 Solute carrier organic anion transporter family member 1B3 28234 reviewed Transporter
Q9NRA0 BXGT021183 Sphingosine kinase 2 56848 reviewed Kinase
Q9NZJ5 BXGT021275 Eukaryotic translation initiation factor 2-alpha kinase 3 9451 reviewed Kinase
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9UBB5 BXGT021649 Methyl-CpG-binding domain protein 2 8932 reviewed Epigenetic regulator
Q9UBN7 BXGT021658 Histone deacetylase 6 10013 reviewed Epigenetic regulator
Q9UGN5 BXGT021688 Poly [ADP-ribose] polymerase 2 10038 reviewed
Q9UN36 BXGT021780 Protein NDRG2 57447 reviewed Enzyme
Q9UNQ0 BXGT021792 ATP-binding cassette sub-family G member 2 9429 reviewed Transporter
Q9UPP1 BXGT021800 Histone lysine demethylase PHF8 23133 reviewed
Q9UQ80 BXGT021806 Proliferation-associated protein 2G4 5036 reviewed
Q9Y289 BXGT022226 Sodium-dependent multivitamin transporter 8884 reviewed Transporter
Q9Y478 BXGT022271 5'-AMP-activated protein kinase subunit beta-1 5564 reviewed Kinase
Q9Y4K0 BXGT022280 Lysyl oxidase homolog 2 4017 reviewed
Q9Y617 BXGT022314 Phosphoserine aminotransferase 29968 reviewed
Q9Y618 BXGT022315 Nuclear receptor corepressor 2 9612 reviewed Transcription factor
Q9Y6Q9 BXGT022338 Nuclear receptor coactivator 3 8202 reviewed Kinase
Q9Y6U3 BXGT022341 Adseverin 85477 reviewed Cellular structure
P04439 BXGT022649 HLA class I histocompatibility antigen, A-3 alpha chain 3105 reviewed
Q92847 BXGT022673 Growth hormone secretagogue receptor type 1 2693 reviewed G-protein coupled receptor
P00738 BXGT022874 Haptoglobin 3240 reviewed Enzyme
P19235 BXGT022895 Erythropoietin receptor 2057 reviewed Receptor
P25054 BXGT022961 Adenomatous polyposis coli protein 324 reviewed
O75317 BXGT023140 Ubiquitin carboxyl-terminal hydrolase 12 219333 reviewed Enzyme
Q96L73 BXGT024676 Histone-lysine N-methyltransferase, H3 lysine-36 specific 64324 reviewed Epigenetic regulator
Q9H040 BXGT024831 SprT-like domain-containing protein Spartan 83932 reviewed
Q9BYC5 BXGT025656 Alpha-(1,6)-fucosyltransferase 2530 reviewed
Q9UQE7 BXGT025899 Structural maintenance of chromosomes protein 3 9126 reviewed
A1L3X0 BXGT025992 Elongation of very long chain fatty acids protein 7 79993 reviewed Enzyme
Q9UHE8 BXGT025995 Metalloreductase STEAP1 26872 reviewed
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
V9HWB9 BXGT026149 L-lactate dehydrogenase 3939 unreviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease