Showing entry for Mucosal addressin cell adhesion molecule 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013361
Protein NameMucosal addressin cell adhesion molecule 1
Uniport IdQ13477
GeneMADCAM1
Gene Id8174
DomainAdhes-Ig_like
Pfam PF09085  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.3 Signaling molecules and interaction hsa04514 Cell adhesion molecules (CAMs)
5. Organismal Systems 5.1 Immune system hsa04672 Intestinal immune network for IgA production
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007155 cell adhesion
Biological Process GO:0007160 cell-matrix adhesion
Biological Process GO:0030198 extracellular matrix organization
Biological Process GO:0034113 heterotypic cell-cell adhesion
Biological Process GO:0006955 immune response
Biological Process GO:0007229 integrin-mediated signaling pathway
Biological Process GO:0050901 leukocyte tethering or rolling
Biological Process GO:0002687 positive regulation of leukocyte migration
Biological Process GO:2000403 positive regulation of lymphocyte migration
Biological Process GO:0043113 receptor clustering
Biological Process GO:0050776 regulation of immune response
Biological Process GO:0007165 signal transduction
molecular function GO:0098640 integrin binding involved in cell-matrix adhesion
cellular component GO:0016021 integral component of membrane
cellular component GO:0016020 membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0004763 BXGD000289 Barrett Esophagus Digestive System Diseases; Neoplasms
C0009319 BXGD000596 Colitis Digestive System Diseases
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0010093 BXGD000652 Corpus Luteum Cyst Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0014070 BXGD000887 Encephalomyelitis Infections; Nervous System Diseases
C0016470 BXGD001060 Food Allergy Immune System Diseases
C0017152 BXGD001096 Gastritis Digestive System Diseases
C0018133 BXGD001176 Graft-vs-Host Disease Immune System Diseases
C0021368 BXGD001502 Inflammation Pathological Conditions, Signs and Symptoms
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0029927 BXGD002182 Ovarian Cysts Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0037221 BXGD002673 Situs Inversus Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0085695 BXGD003243 Chronic gastritis Digestive System Diseases
C0151798 BXGD003477 Hepatic necrosis Digestive System Diseases
C0156147 BXGD003838 Crohn's disease of large bowel Digestive System Diseases
C0162359 BXGD003939 Christ-Siemens-Touraine syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0242647 BXGD005184 Mucosa-Associated Lymphoid Tissue Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0267778 BXGD005773 Adhesion of intestine Digestive System Diseases
C0566602 BXGD009489 Primary sclerosing cholangitis Digestive System Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0850666 BXGD010901 Infection caused by Helicobacter pylori Infections
C0856825 BXGD011118 Acute GVH disease Immune System Diseases
C0867389 BXGD011300 Chronic graft-versus-host disease Immune System Diseases
C0949690 BXGD011584 Spondylarthritis Musculoskeletal Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1636149 BXGD013482 Macular dystrophy, corneal type 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C1706004 BXGD013569 Anhydrotic Ectodermal Dysplasias Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C1850900 BXGD015186 Familial primary gastric lymphoma Digestive System Diseases; Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C2711227 BXGD017478 Steatohepatitis Digestive System Diseases
C3241937 BXGD018578 Nonalcoholic Steatohepatitis Digestive System Diseases
C4529962 BXGD023178 Fatty Liver Disease
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein