Showing entry for Crohn's disease of large bowel


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD003838
Disease NameCrohn's disease of large bowel
Disease CUI IdC0156147
MeSH Codes C06  
Disease Class NameDigestive System Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O15111 BXGT004126 Inhibitor of nuclear factor kappa-B kinase subunit alpha 1147 reviewed Kinase
O43318 BXGT004586 Mitogen-activated protein kinase kinase kinase 7 6885 reviewed Kinase
O95750 BXGT005395 Fibroblast growth factor 19 9965 reviewed Signaling
P01111 BXGT005731 GTPase NRas 4893 reviewed Enzyme modulator
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01589 BXGT005773 Interleukin-2 receptor subunit alpha 3559 reviewed Receptor
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P02766 BXGT005953 Transthyretin 7276 reviewed Transporter
P04004 BXGT006125 Vitronectin 7448 reviewed
P04054 BXGT006136 Phospholipase A2 5319 reviewed Enzyme
P05231 BXGT006345 Interleukin-6 3569 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P17706 BXGT008330 Tyrosine-protein phosphatase non-receptor type 2 5771 reviewed
P19438 BXGT008480 Tumor necrosis factor receptor superfamily member 1A 7132 reviewed
P25963 BXGT009080 NF-kappa-B inhibitor alpha 4792 reviewed
P29460 BXGT009348 Interleukin-12 subunit beta 3593 reviewed Signaling
P29597 BXGT009367 Non-receptor tyrosine-protein kinase TYK2 7297 reviewed Kinase
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P40692 BXGT010195 DNA mismatch repair protein Mlh1 4292 reviewed Nucleic acid binding
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P49116 BXGT010678 Nuclear receptor subfamily 2 group C member 2 7182 reviewed Nuclear receptor
P51686 BXGT010881 C-C chemokine receptor type 9 10803 reviewed G-protein coupled receptor
P60022 BXGT011285 Beta-defensin 1 1672 reviewed
P61626 BXGT011382 Lysozyme C 4069 reviewed
P63104 BXGT011499 14-3-3 protein zeta/delta 7534 reviewed Chaperone
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 4088 reviewed Transcription factor
Q01523 BXGT012594 Defensin-5 1670 reviewed
Q06124 BXGT012856 Tyrosine-protein phosphatase non-receptor type 11 5781 reviewed
Q07869 BXGT012945 Peroxisome proliferator-activated receptor alpha 5465 reviewed Nuclear receptor
Q13477 BXGT013361 Mucosal addressin cell adhesion molecule 1 8174 reviewed
Q15080 BXGT013535 Neutrophil cytosol factor 4 4689 reviewed
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q5NUL3 BXGT015621 Free fatty acid receptor 4 338557 reviewed
Q5VWK5 BXGT015891 Interleukin-23 receptor 149233 reviewed Signaling
Q676U5 BXGT016177 Autophagy-related protein 16-1 55054 reviewed
Q6P179 BXGT016440 Endoplasmic reticulum aminopeptidase 2 64167 reviewed Enzyme
Q8TDU6 BXGT018814 G-protein coupled bile acid receptor 1 151306 reviewed G-protein coupled receptor
Q92835 BXGT019382 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 3635 reviewed
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q96RI1 BXGT019727 Bile acid receptor 9971 reviewed Nuclear receptor
Q9GZX6 BXGT020428 Interleukin-22 50616 reviewed
Q9HC29 BXGT020526 Nucleotide-binding oligomerization domain-containing protein 2 64127 reviewed Enzyme
Q9NR96 BXGT021181 Toll-like receptor 9 54106 reviewed
Q9UKU7 BXGT021749 Isobutyryl-CoA dehydrogenase, mitochondrial 27034 reviewed Enzyme
Q9Y6K1 BXGT022331 DNA (cytosine-5)-methyltransferase 3A 1788 reviewed
P25090 BXGT025102 N-formyl peptide receptor 2 2358 reviewed G-protein coupled receptor
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
Q9Y2I7 BXGT026142 1-phosphatidylinositol 3-phosphate 5-kinase 200576 reviewed Kinase
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease