Showing entry for Chronic graft-versus-host disease


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD011300
Disease NameChronic graft-versus-host disease
Disease CUI IdC0867389
MeSH Codes C20  
Disease Class NameImmune System Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O15550 BXGT004179 Lysine-specific demethylase 6A 7403 reviewed Epigenetic regulator
O43813 BXGT004628 Glutathione S-transferase LANCL1 10314 reviewed
O60603 BXGT004887 Toll-like receptor 2 7097 reviewed
O60858 BXGT004903 E3 ubiquitin-protein ligase TRIM13 10206 reviewed
O75116 BXGT005100 Rho-associated protein kinase 2 9475 reviewed Kinase
O75251 BXGT005107 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial 374291 reviewed
O75460 BXGT005127 Serine/threonine-protein kinase/endoribonuclease IRE1 2081 reviewed Kinase
O95786 BXGT005396 Probable ATP-dependent RNA helicase DDX58 23586 reviewed
P00519 BXGT005570 Tyrosine-protein kinase ABL1 25 reviewed Kinase
P01009 BXGT005714 Alpha-1-antitrypsin 5265 reviewed Enzyme modulator
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01023 BXGT005718 Alpha-2-macroglobulin 2 reviewed Enzyme modulator
P01031 BXGT005720 Complement C5 727 reviewed Enzyme modulator
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01589 BXGT005773 Interleukin-2 receptor subunit alpha 3559 reviewed Receptor
P01889 BXGT005809 HLA class I histocompatibility antigen, B-7 alpha chain 3106 reviewed
P01920 BXGT005817 HLA class II histocompatibility antigen, DQ beta 1 chain 3119 reviewed Immune response
P02753 BXGT005945 Retinol-binding protein 4 5950 reviewed Transporter
P02775 BXGT005960 Platelet basic protein 5473 reviewed Signaling
P02787 BXGT005962 Serotransferrin 7018 reviewed Enzyme
P04070 BXGT006143 Vitamin K-dependent protein C 5624 reviewed Enzyme
P04278 BXGT006182 Sex hormone-binding globulin 6462 reviewed
P04440 BXGT006216 HLA class II histocompatibility antigen, DP beta 1 chain 3115 reviewed Immune response
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05109 BXGT006318 Protein S100-A8 6279 reviewed Calcium-binding protein
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P06126 BXGT006412 T-cell surface glycoprotein CD1a 909 reviewed
P06727 BXGT006485 Apolipoprotein A-IV 337 reviewed
P06748 BXGT006497 Nucleophosmin 4869 reviewed Chaperone
P07204 BXGT006567 Thrombomodulin 7056 reviewed
P08151 BXGT006731 Zinc finger protein GLI1 2735 reviewed
P08254 BXGT006758 Stromelysin-1 4314 reviewed Enzyme
P08865 BXGT006832 40S ribosomal protein SA 3921 reviewed Nucleic acid binding
P09874 BXGT006934 Poly [ADP-ribose] polymerase 1 142 reviewed
P09914 BXGT006940 Interferon-induced protein with tetratricopeptide repeats 1 3434 reviewed
P0DMV8 BXGT007509 Heat shock 70 kDa protein 1A 3304 reviewed
P0DMV9 BXGT007510 Heat shock 70 kDa protein 1B 3304 reviewed
P10070 BXGT007534 Zinc finger protein GLI2 2736 reviewed
P10599 BXGT007583 Thioredoxin 7295 reviewed
P10644 BXGT007597 cAMP-dependent protein kinase type I-alpha regulatory subunit 5573 reviewed
P10747 BXGT007609 T-cell-specific surface glycoprotein CD28 940 reviewed
P10909 BXGT007630 Clusterin 1191 reviewed
P11169 BXGT007664 Solute carrier family 2, facilitated glucose transporter member 3 6515 reviewed Transporter
P11215 BXGT007672 Integrin alpha-M 3684 reviewed
P11274 BXGT007681 Breakpoint cluster region protein 613 reviewed Enzyme modulator
P13501 BXGT007917 C-C motif chemokine 5 6352 reviewed Signaling
P14151 BXGT007990 L-selectin 6402 reviewed
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14672 BXGT008037 Solute carrier family 2, facilitated glucose transporter member 4 6517 reviewed Transporter
P15144 BXGT008087 Aminopeptidase N 290 reviewed Enzyme
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P15813 BXGT008158 Antigen-presenting glycoprotein CD1d 912 reviewed
P16234 BXGT008209 Platelet-derived growth factor receptor alpha 5156 reviewed Kinase
P16410 BXGT008224 Cytotoxic T-lymphocyte protein 4 1493 reviewed
P16442 BXGT008227 Histo-blood group ABO system transferase 28 reviewed Enzyme
P16581 BXGT008245 E-selectin 6401 reviewed
P16871 BXGT008269 Interleukin-7 receptor subunit alpha 3575 reviewed Receptor
P17861 BXGT008348 X-box-binding protein 1 7494 reviewed
P17931 BXGT008356 Galectin-3 3958 reviewed Signaling
P19971 BXGT008537 Thymidine phosphorylase 1890 reviewed Enzyme
P20273 BXGT008557 B-cell receptor CD22 933 reviewed
P20702 BXGT008592 Integrin alpha-X 3687 reviewed
P20839 BXGT008608 Inosine-5'-monophosphate dehydrogenase 1 3614 reviewed Enzyme
P21730 BXGT008687 C5a anaphylatoxin chemotactic receptor 1 728 reviewed G-protein coupled receptor
P23458 BXGT008868 Tyrosine-protein kinase JAK1 3716 reviewed Kinase
P25116 BXGT009025 Proteinase-activated receptor 1 2149 reviewed G-protein coupled receptor
P27487 BXGT009187 Dipeptidyl peptidase 4 1803 reviewed Enzyme
P27815 BXGT009208 cAMP-specific 3',5'-cyclic phosphodiesterase 4A 5141 reviewed
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P28907 BXGT009301 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 952 reviewed Enzyme
P28908 BXGT009302 Tumor necrosis factor receptor superfamily member 8 943 reviewed
P30556 BXGT009441 Type-1 angiotensin II receptor 185 reviewed G-protein coupled receptor
P30566 BXGT009446 Adenylosuccinate lyase 158 reviewed Enzyme
P34931 BXGT009771 Heat shock 70 kDa protein 1-like 3305 reviewed
P35372 BXGT009823 Mu-type opioid receptor 4988 reviewed G-protein coupled receptor
P36888 BXGT009938 Receptor-type tyrosine-protein kinase FLT3 2322 reviewed Kinase
P36897 BXGT009941 TGF-beta receptor type-1 7046 reviewed Kinase
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41180 BXGT010230 Extracellular calcium-sensing receptor 846 reviewed G-protein coupled receptor
P41182 BXGT010231 B-cell lymphoma 6 protein 604 reviewed
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P43405 BXGT010386 Tyrosine-protein kinase SYK 6850 reviewed Kinase
P45984 BXGT010495 Mitogen-activated protein kinase 9 5601 reviewed Kinase
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P50052 BXGT010768 Type-2 angiotensin II receptor 186 reviewed G-protein coupled receptor
P50591 BXGT010814 Tumor necrosis factor ligand superfamily member 10 8743 reviewed Signaling
P51665 BXGT010874 26S proteasome non-ATPase regulatory subunit 7 5713 reviewed Enzyme
P51681 BXGT010878 C-C chemokine receptor type 5 1234 reviewed G-protein coupled receptor
P51684 BXGT010880 C-C chemokine receptor type 6 1235 reviewed G-protein coupled receptor
P55040 BXGT011099 GTP-binding protein GEM 2669 reviewed
P60568 BXGT011315 Interleukin-2 3558 reviewed
P78310 BXGT011830 Coxsackievirus and adenovirus receptor 1525 reviewed
P80188 BXGT011882 Neutrophil gelatinase-associated lipocalin 3934 reviewed Enzyme
Q04721 BXGT012777 Neurogenic locus notch homolog protein 2 4853 reviewed
Q06187 BXGT012860 Tyrosine-protein kinase BTK 695 reviewed Kinase
Q07820 BXGT012942 Induced myeloid leukemia cell differentiation protein Mcl-1 4170 reviewed Signaling
Q13085 BXGT013309 Acetyl-CoA carboxylase 1 31 reviewed
Q13477 BXGT013361 Mucosal addressin cell adhesion molecule 1 8174 reviewed
Q14457 BXGT013472 Beclin-1 8678 reviewed Enzyme modulator
Q14994 BXGT013519 Nuclear receptor subfamily 1 group I member 3 9970 reviewed Nuclear receptor
Q15722 BXGT013590 Leukotriene B4 receptor 1 1241 reviewed G-protein coupled receptor
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q16539 BXGT013634 Mitogen-activated protein kinase 14 1432 reviewed Kinase
Q16548 BXGT013636 Bcl-2-related protein A1 597 reviewed Signaling
Q5VWK5 BXGT015891 Interleukin-23 receptor 149233 reviewed Signaling
Q5Y7D3 BXGT015912 HLA class II histocompatibility antigen DQ beta chain 3119 unreviewed
Q6N021 BXGT016378 Methylcytosine dioxygenase TET2 54790 reviewed
Q8TDQ0 BXGT018810 Hepatitis A virus cellular receptor 2 84868 reviewed
Q96AZ6 BXGT019621 Interferon-stimulated gene 20 kDa protein 3669 reviewed
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96PD4 BXGT019705 Interleukin-17F 112744 reviewed
Q99835 BXGT019969 Smoothened homolog 6608 reviewed G-protein coupled receptor
Q9BXA7 BXGT020164 Testis-specific serine/threonine-protein kinase 1 83942 reviewed Kinase
Q9BYT8 BXGT020190 Neurolysin, mitochondrial 57486 reviewed Enzyme
Q9BZS1 BXGT020203 Forkhead box protein P3 50943 reviewed
Q9GZX6 BXGT020428 Interleukin-22 50616 reviewed
Q9HC29 BXGT020526 Nucleotide-binding oligomerization domain-containing protein 2 64127 reviewed Enzyme
Q9NR96 BXGT021181 Toll-like receptor 9 54106 reviewed
Q9NYK1 BXGT021258 Toll-like receptor 7 51284 reviewed
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9P2W7 BXGT021306 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 27087 reviewed Enzyme
Q9UM07 BXGT021771 Protein-arginine deiminase type-4 23569 reviewed
Q9Y251 BXGT022215 Heparanase 10855 reviewed Enzyme
Q9Y275 BXGT022223 Tumor necrosis factor ligand superfamily member 13B 10673 reviewed
P04439 BXGT022649 HLA class I histocompatibility antigen, A-3 alpha chain 3105 reviewed
P00738 BXGT022874 Haptoglobin 3240 reviewed Enzyme
P16284 BXGT022972 Platelet endothelial cell adhesion molecule 5175 reviewed Cell adhesion
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
Q96QC4 BXGT023878 MHC class I polypeptide-related sequence A 100507436 unreviewed
P19474 BXGT025520 E3 ubiquitin-protein ligase TRIM21 6737 reviewed
P11836 BXGT025994 B-lymphocyte antigen CD20 931 reviewed Receptor
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease