Showing entry for Protein scribble homolog


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013450
Protein NameProtein scribble homolog
Uniport IdQ14160
GeneSCRIB
Gene Id23513
DomainLRR_8; PDZ
Pfam PF13855   PF00595  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04390 Hippo signaling pathway
4. Cellular Processes 4.3 Cellular community - eukaryotes hsa04530 Tight junction
6. Human Diseases 6.9 Infectious diseases: Viral hsa05165 Human papillomavirus infection
6. Human Diseases 6.1 Cancers: Overview hsa05203 Viral carcinogenesis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0090630 activation of GTPase activity
Biological Process GO:0060561 apoptotic process involved in morphogenesis
Biological Process GO:0043615 astrocyte cell migration
Biological Process GO:0060088 auditory receptor cell stereocilium organization
Biological Process GO:0098609 cell-cell adhesion
Biological Process GO:0016477 cell migration
Biological Process GO:0008283 cell population proliferation
Biological Process GO:0021747 cochlear nucleus development
Biological Process GO:0035089 establishment of apical/basal cell polarity
Biological Process GO:0001768 establishment of T cell polarity
Biological Process GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity
Biological Process GO:0060603 mammary gland duct morphogenesis
Biological Process GO:0030683 mitigation of host immune response by virus
Biological Process GO:0046007 negative regulation of activated T cell proliferation
Biological Process GO:0045930 negative regulation of mitotic cell cycle
Biological Process GO:0001843 neural tube closure
Biological Process GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane
Biological Process GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome
Biological Process GO:0030859 polarized epithelial cell differentiation
Biological Process GO:0050918 positive chemotaxis
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:0032729 positive regulation of interferon-gamma production
Biological Process GO:0001921 positive regulation of receptor recycling
Biological Process GO:0071896 protein localization to adherens junction
Biological Process GO:0043113 receptor clustering
Biological Process GO:0097120 receptor localization to synapse
Biological Process GO:0039563 suppression by virus of host STAT1 activity
Biological Process GO:0039564 suppression by virus of host STAT2 activity
Biological Process GO:0048488 synaptic vesicle endocytosis
Biological Process GO:0016080 synaptic vesicle targeting
Biological Process GO:0042060 wound healing
molecular function GO:0045296 cadherin binding
cellular component GO:0005912 adherens junction
cellular component GO:0016323 basolateral plasma membrane
cellular component GO:0044291 cell-cell contact zone
cellular component GO:0005911 cell-cell junction
cellular component GO:0030054 cell junction
cellular component GO:0070062 extracellular exosome
cellular component GO:0099147 extrinsic component of postsynaptic density membrane
cellular component GO:0098978 glutamatergic synapse
cellular component GO:0001772 immunological synapse
cellular component GO:0030027 lamellipodium
cellular component GO:0035748 myelin sheath abaxonal region
cellular component GO:0005654 nucleoplasm
cellular component GO:0005886 plasma membrane
cellular component GO:0014069 postsynaptic density
cellular component GO:0098793 presynapse
cellular component GO:0034750 Scrib-APC-beta-catenin complex
cellular component GO:0045202 synapse
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-195721 Signaling by WNT
R-HSA-3858494 Beta-catenin independent WNT signaling
R-HSA-4086400 PCP/CE pathway
R-HSA-4608870 Asymmetric localization of PCP proteins
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002902 BXGD000154 Anencephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0009363 BXGD000599 Congenital ocular coloboma (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0009375 BXGD000602 Colonic Neoplasms Digestive System Diseases; Neoplasms
C0025958 BXGD001882 Microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0027794 BXGD002036 Neural Tube Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0030354 BXGD002214 Papilloma Neoplasms
C0032580 BXGD002362 Adenomatous Polyposis Coli Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0080178 BXGD003107 Spina Bifida Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0085413 BXGD003171 Polycystic Kidney, Autosomal Dominant Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0085548 BXGD003183 Autosomal Recessive Polycystic Kidney Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0152426 BXGD003589 Craniorachischisis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0431128 BXGD008664 Papillary craniopharyngioma Neoplasms
C0476089 BXGD008977 Endometrial Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1535939 BXGD013323 Pneumocystis jiroveci pneumonia Infections; Respiratory Tract Diseases
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C3810023 BXGD019630 VERHEIJ SYNDROME
C3891448 BXGD020030 NEURAL TUBE DEFECTS, SUSCEPTIBILITY TO
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003705 Chloride 35.45
BXGC0006368 Formic acid 46.03
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein