adisease

Showing entry for Papilloma

General Disease Information
BXGD Id	BXGD002214
Disease Name	Papilloma
Disease CUI Id	C0030354
MeSH Codes	C04
Disease Class Name	Neoplasms
Semantic Type	Neoplastic Process
Human Phenotype Ontology Id	HP:0001574 HP:0002664
Human Phenotype Ontology Term	Abnormality of the integument; Neoplasm
Disease Ontology Id	DOID:14566
Disease Ontology Class Name	disease of cellular proliferation
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
O00329	BXGT003909	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	5293	reviewed	Kinase
O14684	BXGT004082	Prostaglandin E synthase	9536	reviewed
O14733	BXGT004087	Dual specificity mitogen-activated protein kinase kinase 7	5609	reviewed	Kinase
O14746	BXGT004091	Telomerase reverse transcriptase	7015	reviewed	Enzyme
O14965	BXGT004117	Aurora kinase A	6790	reviewed	Kinase
O15111	BXGT004126	Inhibitor of nuclear factor kappa-B kinase subunit alpha	1147	reviewed	Kinase
O15527	BXGT004176	N-glycosylase/DNA lyase	4968	reviewed
O43854	BXGT004630	EGF-like repeat and discoidin I-like domain-containing protein 3	10085	reviewed	Enzyme
O60260	BXGT004864	E3 ubiquitin-protein ligase parkin	5071	reviewed	Enzyme
O75116	BXGT005100	Rho-associated protein kinase 2	9475	reviewed	Kinase
O76054	BXGT005172	SEC14-like protein 2	23541	reviewed
O94925	BXGT005342	Glutaminase kidney isoform, mitochondrial	2744	reviewed	Enzyme
P00352	BXGT005510	Retinal dehydrogenase 1	216	reviewed	Enzyme
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P00750	BXGT005642	Tissue-type plasminogen activator	5327	reviewed	Enzyme
P01106	BXGT005730	Myc proto-oncogene protein	4609	reviewed	Transcription factor
P01111	BXGT005731	GTPase NRas	4893	reviewed	Enzyme modulator
P01112	BXGT005732	GTPase HRas	3265	reviewed	Enzyme modulator
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P01133	BXGT005736	Pro-epidermal growth factor	1950	reviewed
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01574	BXGT005768	Interferon beta	3456	reviewed
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01589	BXGT005773	Interleukin-2 receptor subunit alpha	3559	reviewed	Receptor
P02100	BXGT005845	Hemoglobin subunit epsilon	3046	reviewed
P02533	BXGT005887	Keratin, type I cytoskeletal 14	3861	reviewed
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02766	BXGT005953	Transthyretin	7276	reviewed	Transporter
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P03956	BXGT006120	Interstitial collagenase	4312	reviewed	Enzyme
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P04179	BXGT006163	Superoxide dismutase [Mn], mitochondrial	6648	reviewed	Enzyme
P04626	BXGT006238	Receptor tyrosine-protein kinase erbB-2	2064	reviewed	Kinase
P04629	BXGT006239	High affinity nerve growth factor receptor	4914	reviewed	Kinase
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P05109	BXGT006318	Protein S100-A8	6279	reviewed	Calcium-binding protein
P05120	BXGT006319	Plasminogen activator inhibitor 2	5055	reviewed	Enzyme modulator
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P06731	BXGT006488	Carcinoembryonic antigen-related cell adhesion molecule 5	1048	reviewed
P07996	BXGT006710	Thrombospondin-1	7057	reviewed
P08138	BXGT006729	Tumor necrosis factor receptor superfamily member 16	4804	reviewed	Receptor
P08246	BXGT006756	Neutrophil elastase	1991	reviewed	Enzyme
P08842	BXGT006830	Steryl-sulfatase	412	reviewed	Enzyme
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10599	BXGT007583	Thioredoxin	7295	reviewed
P10644	BXGT007597	cAMP-dependent protein kinase type I-alpha regulatory subunit	5573	reviewed
P10721	BXGT007605	Mast/stem cell growth factor receptor Kit	3815	reviewed	Kinase
P10747	BXGT007609	T-cell-specific surface glycoprotein CD28	940	reviewed
P10826	BXGT007622	Retinoic acid receptor beta	5915	reviewed	Nuclear receptor
P10909	BXGT007630	Clusterin	1191	reviewed
P11166	BXGT007661	Solute carrier family 2, facilitated glucose transporter member 1	6513	reviewed	Transporter
P11802	BXGT007750	Cyclin-dependent kinase 4	1019	reviewed	Kinase
P11926	BXGT007760	Ornithine decarboxylase	4953	reviewed	Enzyme
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P13647	BXGT007937	Keratin, type II cytoskeletal 5	3852	reviewed
P14210	BXGT007994	Hepatocyte growth factor	3082	reviewed	Enzyme
P14679	BXGT008039	Tyrosinase	7299	reviewed	Enzyme
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P15559	BXGT008139	NAD(P)H dehydrogenase [quinone] 1	1728	reviewed
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P16278	BXGT008213	Beta-galactosidase	2720	reviewed	Enzyme
P16455	BXGT008229	Methylated-DNA--protein-cysteine methyltransferase	4255	reviewed
P16871	BXGT008269	Interleukin-7 receptor subunit alpha	3575	reviewed	Receptor
P17936	BXGT008357	Insulin-like growth factor-binding protein 3	3486	reviewed	Enzyme modulator
P18074	BXGT008374	General transcription and DNA repair factor IIH helicase subunit XPD	2068	reviewed	Enzyme
P18827	BXGT008427	Syndecan-1	6382	reviewed	Extracellular structure
P20936	BXGT008619	Ras GTPase-activating protein 1	5921	reviewed	Enzyme modulator
P21860	BXGT008698	Receptor tyrosine-protein kinase erbB-3	2065	reviewed	Kinase
P22607	BXGT008784	Fibroblast growth factor receptor 3	2261	reviewed	Kinase
P24385	BXGT008965	G1/S-specific cyclin-D1	595	reviewed	Enzyme modulator
P26358	BXGT009104	DNA (cytosine-5)-methyltransferase 1	1786	reviewed	Epigenetic regulator
P27797	BXGT009206	Calreticulin	811	reviewed	Calcium-binding protein
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P29323	BXGT009334	Ephrin type-B receptor 2	2048	reviewed	Kinase
P30281	BXGT009416	G1/S-specific cyclin-D3	896	reviewed	Enzyme modulator
P31749	BXGT009574	RAC-alpha serine/threonine-protein kinase	207	reviewed	Kinase
P31947	BXGT009589	14-3-3 protein sigma	2810	reviewed	Chaperone
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	672	reviewed	Enzyme
P38936	BXGT010074	Cyclin-dependent kinase inhibitor 1	1026	reviewed
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P41279	BXGT010254	Mitogen-activated protein kinase kinase kinase 8	1326	reviewed	Kinase
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42338	BXGT010303	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	5291	reviewed	Kinase
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P43403	BXGT010385	Tyrosine-protein kinase ZAP-70	7535	reviewed	Kinase
P46531	BXGT010526	Neurogenic locus notch homolog protein 1	4851	reviewed
P46937	BXGT010554	Transcriptional coactivator YAP1	10413	reviewed	Enzyme modulator
P47712	BXGT010577	Cytosolic phospholipase A2	5321	reviewed	Enzyme
P48736	BXGT010658	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	5294	reviewed	Kinase
P49023	BXGT010672	Paxillin	5829	reviewed	Cellular structure
P49763	BXGT010737	Placenta growth factor	5228	reviewed	Signaling
P49789	BXGT010742	Bis(5'-adenosyl)-triphosphatase	2272	reviewed
P51681	BXGT010878	C-C chemokine receptor type 5	1234	reviewed	G-protein coupled receptor
P51843	BXGT010897	Nuclear receptor subfamily 0 group B member 1	190	reviewed	Nuclear receptor
P55040	BXGT011099	GTP-binding protein GEM	2669	reviewed
P55774	BXGT011124	C-C motif chemokine 18	6362	reviewed	Signaling
P55899	BXGT011131	IgG receptor FcRn large subunit p51	2217	reviewed
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P63000	BXGT011481	Ras-related C3 botulinum toxin substrate 1	5879	reviewed	Enzyme modulator
P63146	BXGT011504	Ubiquitin-conjugating enzyme E2 B	7320	reviewed
P68036	BXGT011572	Ubiquitin-conjugating enzyme E2 L3	7332	reviewed	Enzyme
P78417	BXGT011843	Glutathione S-transferase omega-1	9446	reviewed
P78556	BXGT011849	C-C motif chemokine 20	6364	reviewed	Signaling
P98170	BXGT012231	E3 ubiquitin-protein ligase XIAP	331	reviewed	Enzyme modulator
Q00534	BXGT012533	Cyclin-dependent kinase 6	1021	reviewed	Kinase
Q00987	BXGT012559	E3 ubiquitin-protein ligase Mdm2	4193	reviewed	Nucleic acid binding
Q01094	BXGT012568	Transcription factor E2F1	1869	reviewed	Nucleic acid binding
Q01453	BXGT012588	Peripheral myelin protein 22	5376	reviewed	Cellular structure
Q01831	BXGT012621	DNA repair protein complementing XP-C cells	7508	reviewed	Nucleic acid binding
Q04912	BXGT012790	Macrophage-stimulating protein receptor	4486	reviewed	Kinase
Q06520	BXGT012880	Bile salt sulfotransferase	6822	reviewed
Q06609	BXGT012884	DNA repair protein RAD51 homolog 1	5888	reviewed
Q07108	BXGT012919	Early activation antigen CD69	969	reviewed
Q07820	BXGT012942	Induced myeloid leukemia cell differentiation protein Mcl-1	4170	reviewed	Signaling
Q07889	BXGT012946	Son of sevenless homolog 1	6654	reviewed	Enzyme modulator
Q07955	BXGT012951	Serine/arginine-rich splicing factor 1	6426	reviewed	Nucleic acid binding
Q08945	BXGT013014	FACT complex subunit SSRP1	6749	reviewed
Q09428	BXGT013036	ATP-binding cassette sub-family C member 8	6833	reviewed	Transporter
Q13118	BXGT013312	Krueppel-like factor 10	7071	reviewed	Nucleic acid binding
Q13546	BXGT013372	Receptor-interacting serine/threonine-protein kinase 1	8737	reviewed	Kinase
Q14160	BXGT013450	Protein scribble homolog	23513	reviewed
Q14576	BXGT013487	ELAV-like protein 3	1995	reviewed
Q15125	BXGT013543	3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	10682	reviewed	Enzyme
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q92876	BXGT019388	Kallikrein-6	5653	reviewed	Enzyme
Q96AZ6	BXGT019621	Interferon-stimulated gene 20 kDa protein	3669	reviewed
Q96GD0	BXGT019665	Pyridoxal phosphate phosphatase	57026	reviewed	Enzyme
Q96HC4	BXGT019671	PDZ and LIM domain protein 5	10611	reviewed	Cellular structure
Q96J66	BXGT019680	ATP-binding cassette sub-family C member 11	85320	reviewed	Transporter
Q99835	BXGT019969	Smoothened homolog	6608	reviewed	G-protein coupled receptor
Q9BZS1	BXGT020203	Forkhead box protein P3	50943	reviewed
Q9HCU9	BXGT020539	Breast cancer metastasis-suppressor 1	25855	reviewed
Q9NP58	BXGT021143	ATP-binding cassette sub-family B member 6, mitochondrial	10058	reviewed	Transporter
Q9NR12	BXGT021174	PDZ and LIM domain protein 7	9260	reviewed	Cellular structure
Q9NZQ7	BXGT021281	Programmed cell death 1 ligand 1	29126	reviewed	Receptor
Q9P2W7	BXGT021306	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1	27087	reviewed	Enzyme
Q9UBC3	BXGT021650	DNA (cytosine-5)-methyltransferase 3B	1789	reviewed
Q9UKU7	BXGT021749	Isobutyryl-CoA dehydrogenase, mitochondrial	27034	reviewed	Enzyme
Q9Y2T6	BXGT022247	G-protein coupled receptor 55	9290	reviewed	G-protein coupled receptor
Q9Y2W7	BXGT022250	Calsenilin	30818	reviewed	Ion channel
O60232	BXGT024169	Protein ZNRD2	10534	reviewed
P29590	BXGT024350	Protein PML	5371	reviewed
Q9BYE2	BXGT024631	Transmembrane protease serine 13	84000	reviewed	Enzyme
Q05086	BXGT025648	Ubiquitin-protein ligase E3A	7337	reviewed
P28715	BXGT025675	DNA repair protein complementing XP-G cells	2073	reviewed
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}