Showing entry for Autosomal Recessive Polycystic Kidney Disease


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD003183
Disease NameAutosomal Recessive Polycystic Kidney Disease
Disease CUI IdC0085548
MeSH Codes C16   C13   C12  
Disease Class NameCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:630   DOID:7  
Disease Ontology Class Namegenetic disease; disease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P08263 BXGT006759 Glutathione S-transferase A1 2938 reviewed
P12004 BXGT007766 Proliferating cell nuclear antigen 5111 reviewed Nucleic acid binding
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P12931 BXGT007859 Proto-oncogene tyrosine-protein kinase Src 6714 reviewed Kinase
P13569 BXGT007923 Cystic fibrosis transmembrane conductance regulator 1080 reviewed Ion channel
P29320 BXGT009332 Ephrin type-A receptor 3 2042 reviewed Kinase
P30304 BXGT009418 M-phase inducer phosphatase 1 993 reviewed Enzyme
P30518 BXGT009428 Vasopressin V2 receptor 554 reviewed G-protein coupled receptor
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P41180 BXGT010230 Extracellular calcium-sensing receptor 846 reviewed G-protein coupled receptor
P41231 BXGT010240 P2Y purinoceptor 2 5029 reviewed G-protein coupled receptor
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P46934 BXGT010553 E3 ubiquitin-protein ligase NEDD4 4734 reviewed Enzyme
P47900 BXGT010595 P2Y purinoceptor 1 5028 reviewed G-protein coupled receptor
P49023 BXGT010672 Paxillin 5829 reviewed Cellular structure
P51575 BXGT010861 P2X purinoceptor 1 5023 reviewed Ion channel
P56373 BXGT011164 P2X purinoceptor 3 5024 reviewed Ion channel
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 4088 reviewed Transcription factor
Q13563 BXGT013377 Polycystin-2 5311 reviewed Ion channel
Q14160 BXGT013450 Protein scribble homolog 23513 reviewed
Q15139 BXGT013546 Serine/threonine-protein kinase D1 5587 reviewed Kinase
Q7Z494 BXGT017254 Nephrocystin-3 27031 reviewed
Q96PY6 BXGT019712 Serine/threonine-protein kinase Nek1 4750 reviewed Kinase
Q99572 BXGT019935 P2X purinoceptor 7 5027 reviewed Ion channel
Q9UBL9 BXGT021656 P2X purinoceptor 2 22953 reviewed Ion channel
Q9H694 BXGT024116 Protein bicaudal C homolog 1 80114 reviewed Transporter
Q96RD7 BXGT025890 Pannexin-1 24145 reviewed Ion channel
Q86SG6 BXGT026136 Serine/threonine-protein kinase Nek8 284086 reviewed Kinase
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease