Showing entry for Receptor-type tyrosine-protein phosphatase R


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013553
Protein NameReceptor-type tyrosine-protein phosphatase R
Uniport IdQ15256
GenePTPRR
Gene Id5801
DomainY_phosphatase
Pfam PF00102  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04010 MAPK signaling pathway
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0038128 ERBB2 signaling pathway
Biological Process GO:0001701 in utero embryonic development
Biological Process GO:0010633 negative regulation of epithelial cell migration
Biological Process GO:0070373 negative regulation of ERK1 and ERK2 cascade
Biological Process GO:0006470 protein dephosphorylation
molecular function GO:0019901 protein kinase binding
molecular function GO:0004725 protein tyrosine phosphatase activity
molecular function GO:0005001 transmembrane receptor protein tyrosine phosphatase activity
cellular component GO:0030054 cell junction
cellular component GO:0005829 cytosol
cellular component GO:0005615 extracellular space
cellular component GO:0016021 integral component of membrane
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0005890 BXGD000345 Body Height
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0015672 BXGD001011 Fatigue Pathological Conditions, Signs and Symptoms
C0019569 BXGD001337 Hirschsprung Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0034951 BXGD002498 Refractive Errors Eye Diseases
C0040420 BXGD002861 Tonometry
C0041696 BXGD002932 Unipolar Depression Mental Disorders
C0042133 BXGD002960 Uterine Fibroids Neoplasms
C0153381 BXGD003626 Malignant neoplasm of mouth Neoplasms; Stomatognathic Diseases
C0220641 BXGD004305 Lip and Oral Cavity Carcinoma Neoplasms; Stomatognathic Diseases
C0271183 BXGD006169 Severe myopia Eye Diseases
C0598766 BXGD009669 Leukemogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1334177 BXGD012684 Infiltrating Cervical Carcinoma
C1739135 BXGD013733 Progression of prostate cancer
C2076600 BXGD016912 Influenza due to Influenza A virus subtype H1N1 Infections; Respiratory Tract Diseases
C2242776 BXGD017001 Plexiform leiomyoma
C4025843 BXGD021823 Abnormality of refraction
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein