Showing entry for Ras-related protein Rab-11B


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013611
Protein NameRas-related protein Rab-11B
Uniport IdQ15907
GeneRAB11B
Gene Id9230
DomainRas
Pfam PF00071  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
4. Cellular Processes 4.1 Transport and catabolism hsa04144 Endocytosis
3. Environmental Information Processing 3.2 Signal transduction hsa04152 AMPK signaling pathway
5. Organismal Systems 5.5 Excretory system hsa04962 Vasopressin-regulated water reabsorption
6. Human Diseases 6.9 Infectious diseases: Viral hsa05164 Influenza A
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0150093 amyloid-beta clearance by transcytosis
Biological Process GO:0071468 cellular response to acidic pH
Biological Process GO:0045054 constitutive secretory pathway
Biological Process GO:0090150 establishment of protein localization to membrane
Biological Process GO:0006887 exocytosis
Biological Process GO:0035773 insulin secretion involved in cellular response to glucose stimulus
Biological Process GO:0032402 melanosome transport
Biological Process GO:0043687 post-translational protein modification
Biological Process GO:0001881 receptor recycling
Biological Process GO:0045055 regulated exocytosis
Biological Process GO:0044070 regulation of anion transport
Biological Process GO:2001135 regulation of endocytic recycling
Biological Process GO:2000008 regulation of protein localization to cell surface
Biological Process GO:1990126 retrograde transport, endosome to plasma membrane
Biological Process GO:0033572 transferrin transport
molecular function GO:0045296 cadherin binding
molecular function GO:0019003 GDP binding
molecular function GO:0003924 GTPase activity
molecular function GO:0005525 GTP binding
molecular function GO:0031489 myosin V binding
cellular component GO:0098993 anchored component of synaptic vesicle membrane
cellular component GO:0005829 cytosol
cellular component GO:0005768 endosome
cellular component GO:0070062 extracellular exosome
cellular component GO:0045335 phagocytic vesicle
cellular component GO:0030670 phagocytic vesicle membrane
cellular component GO:0055037 recycling endosome
cellular component GO:0055038 recycling endosome membrane
cellular component GO:0008021 synaptic vesicle
Reactome
Pathway Id Pathway Name
R-HSA-199991 Membrane Trafficking
R-HSA-392499 Metabolism of proteins
R-HSA-5653656 Vesicle-mediated transport
R-HSA-597592 Post-translational protein modification
R-HSA-8854214 TBC/RABGAPs
R-HSA-8873719 RAB geranylgeranylation
R-HSA-9007101 Rab regulation of trafficking
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001418 BXGD000050 Adenocarcinoma Neoplasms
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0007113 BXGD000430 Rectal Carcinoma Digestive System Diseases; Neoplasms
C0009081 BXGD000581 Congenital clubfoot Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0013421 BXGD000837 Dystonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0014859 BXGD000961 Esophageal Neoplasms Digestive System Diseases; Neoplasms
C0019693 BXGD001346 HIV Infections Infections; Immune System Diseases
C0020490 BXGD001403 Hyperopia Eye Diseases
C0025958 BXGD001882 Microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0026838 BXGD001938 Muscle Spasticity Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0028738 BXGD002081 Nystagmus Eye Diseases; Nervous System Diseases
C0029124 BXGD002113 Optic Atrophy Eye Diseases; Nervous System Diseases
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0038271 BXGD002742 Stereotyped Behavior Behavior and Behavior Mechanisms
C0038273 BXGD002743 Stereotypic Movement Disorder Mental Disorders
C0038379 BXGD002752 Strabismus Eye Diseases; Nervous System Diseases
C0039273 BXGD002806 Talipes cavus Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0205682 BXGD004105 Waist-Hip Ratio
C0231686 BXGD004508 Gait, Unsteady Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0232466 BXGD004543 Feeding difficulties
C0241726 BXGD005110 Delayed ability to walk
C0265610 BXGD005555 Clinodactyly of fingers Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0281361 BXGD006774 Adenocarcinoma of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0311394 BXGD006884 Difficulty walking Pathological Conditions, Signs and Symptoms
C0423109 BXGD008470 Upward slant of palpebral fissure
C0424503 BXGD008532 Dysmorphic facies
C0424731 BXGD008542 Single transverse palmar crease Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0426886 BXGD008594 Tapering fingers (finding)
C0557874 BXGD009444 Global developmental delay
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0751837 BXGD010604 Gait Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0857379 BXGD011148 Abnormality of the pinna
C0920299 BXGD011465 Overriding toe Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1277241 BXGD012110 Delayed myelination Mental Disorders
C1328407 BXGD012465 Hip Dysplasia Musculoskeletal Diseases; Wounds and Injuries
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C1445953 BXGD013080 Poor eye contact Mental Disorders
C1839767 BXGD014404 Tented upper lip vermilion
C1840379 BXGD014459 Cerebellar vermis hypoplasia
C1845251 BXGD014734 Facial hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1854882 BXGD015439 Absent speech Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1856115 BXGD015574 Happy demeanor
C1858120 BXGD015774 Generalized hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1963184 BXGD016688 Nystagmus, CTCAE 3.0
C3150943 BXGD018362 Long Qt Syndrome 2 Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C3665347 BXGD019279 Visual Impairment Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C4505456 BXGD022964 HIV Coinfection Infections; Immune System Diseases
C4540498 BXGD023265 NEURODEVELOPMENTAL DISORDER WITH ATAXIC GAIT, ABSENT SPEECH, AND DECREASED CORTICAL WHITE MATTER
C4551485 BXGD023312 Clinodactyly
C4553743 BXGD023548 Spasticity, CTCAE
C4554036 BXGD023557 Nystagmus, CTCAE 5.0
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein