adisease

Showing entry for Absent speech

General Disease Information
BXGD Id	BXGD015439
Disease Name	Absent speech
Disease CUI Id	C1854882
MeSH Codes	C23 C10
Disease Class Name	Pathological Conditions, Signs and Symptoms; Nervous System Diseases
Semantic Type	Finding
Human Phenotype Ontology Id	HP:0000707
Human Phenotype Ontology Term	Abnormality of the nervous system
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O14764	BXGT004094	Gamma-aminobutyric acid receptor subunit delta	2563	reviewed	Ion channel
O14936	BXGT004114	Peripheral plasma membrane protein CASK	8573	reviewed	Kinase
O15247	BXGT004142	Chloride intracellular channel protein 2	1193	reviewed	Ion channel
O15399	BXGT004164	Glutamate receptor ionotropic, NMDA 2D	2906	reviewed	Ion channel
O75746	BXGT005148	Calcium-binding mitochondrial carrier protein Aralar1	8604	reviewed	Transporter
O75899	BXGT005161	Gamma-aminobutyric acid type B receptor subunit 2	9568	reviewed	G-protein coupled receptor
O95363	BXGT005375	Phenylalanine--tRNA ligase, mitochondrial	10667	reviewed	Enzyme
P04066	BXGT006142	Tissue alpha-L-fucosidase	2517	reviewed
P11166	BXGT007661	Solute carrier family 2, facilitated glucose transporter member 1	6513	reviewed	Transporter
P15884	BXGT008166	Transcription factor 4	6925	reviewed	Transcription factor
P16389	BXGT008221	Potassium voltage-gated channel subfamily A member 2	3737	reviewed	Ion channel
P18507	BXGT008411	Gamma-aminobutyric acid receptor subunit gamma-2	2566	reviewed	Ion channel
P30153	BXGT009409	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform	5518	reviewed	Enzyme
P30279	BXGT009415	G1/S-specific cyclin-D2	894	reviewed	Enzyme modulator
P30566	BXGT009446	Adenylosuccinate lyase	158	reviewed	Enzyme
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P36021	BXGT009893	Monocarboxylate transporter 8	6567	reviewed	Transporter
P40926	BXGT010207	Malate dehydrogenase, mitochondrial	4191	reviewed	Enzyme
P42345	BXGT010304	Serine/threonine-protein kinase mTOR	2475	reviewed	Kinase
P42858	BXGT010341	Huntingtin	3064	reviewed
P43004	BXGT010348	Excitatory amino acid transporter 2	6506	reviewed	Transporter
P43007	BXGT010350	Neutral amino acid transporter A	6509	reviewed	Transporter
P46100	BXGT010508	Transcriptional regulator ATRX	546	reviewed
P47870	BXGT010591	Gamma-aminobutyric acid receptor subunit beta-2	2561	reviewed	Ion channel
P48058	BXGT010614	Glutamate receptor 4	2893	reviewed	Ion channel
P51531	BXGT010851	Probable global transcription activator SNF2L2	6595	reviewed	Epigenetic regulator
P52788	BXGT010953	Spermine synthase	6611	reviewed
P54886	BXGT011092	Delta-1-pyrroline-5-carboxylate synthase	5832	reviewed	Enzyme
P57059	BXGT011210	Serine/threonine-protein kinase SIK1	150094	reviewed
P58400	BXGT011235	Neurexin-1-beta	9378	reviewed
P60891	BXGT011337	Ribose-phosphate pyrophosphokinase 1	5631	reviewed	Kinase
P60953	BXGT011342	Cell division control protein 42 homolog	998	reviewed	Enzyme modulator
P63000	BXGT011481	Ras-related C3 botulinum toxin substrate 1	5879	reviewed	Enzyme modulator
P68400	BXGT011599	Casein kinase II subunit alpha	1457	reviewed	Kinase
Q00975	BXGT012558	Voltage-dependent N-type calcium channel subunit alpha-1B	774	reviewed	Ion channel
Q01959	BXGT012624	Sodium-dependent dopamine transporter	6531	reviewed	Transporter
Q05193	BXGT012810	Dynamin-1	1759	reviewed	Enzyme modulator
Q05586	BXGT012826	Glutamate receptor ionotropic, NMDA 1	2902	reviewed	Ion channel
Q08209	BXGT012968	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	5530	reviewed
Q12756	BXGT013261	Kinesin-like protein KIF1A	547	reviewed	Cellular structure
Q13155	BXGT013320	Aminoacyl tRNA synthase complex-interacting multifunctional protein 2	7965	reviewed
Q13224	BXGT013328	Glutamate receptor ionotropic, NMDA 2B	2904	reviewed	Ion channel
Q13255	BXGT013332	Metabotropic glutamate receptor 1	2911	reviewed	G-protein coupled receptor
Q13303	BXGT013336	Voltage-gated potassium channel subunit beta-2	8514	reviewed	Ion channel
Q13554	BXGT013374	Calcium/calmodulin-dependent protein kinase type II subunit beta	816	reviewed	Kinase
Q13586	BXGT013380	Stromal interaction molecule 1	6786	reviewed
Q13627	BXGT013385	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	1859	reviewed	Kinase
Q14004	BXGT013435	Cyclin-dependent kinase 13	8621	reviewed	Kinase
Q14118	BXGT013444	Dystroglycan	1605	reviewed	Receptor
Q14721	BXGT013502	Potassium voltage-gated channel subfamily B member 1	3745	reviewed	Ion channel
Q15751	BXGT013593	Probable E3 ubiquitin-protein ligase HERC1	8925	reviewed	Enzyme modulator
Q15907	BXGT013611	Ras-related protein Rab-11B	9230	reviewed
Q16620	BXGT013645	BDNF/NT-3 growth factors receptor	4915	reviewed	Kinase
Q5JPH6	BXGT015456	Probable glutamate--tRNA ligase, mitochondrial	124454	reviewed	Enzyme
Q6PI48	BXGT016471	Aspartate--tRNA ligase, mitochondrial	55157	reviewed	Enzyme
Q7L3T8	BXGT016994	Probable proline--tRNA ligase, mitochondrial	25973	reviewed	Enzyme
Q7RTN6	BXGT017085	STE20-related kinase adapter protein alpha	92335	reviewed	Kinase
Q8NFD5	BXGT018560	AT-rich interactive domain-containing protein 1B	57492	reviewed
Q8TCS8	BXGT018799	Polyribonucleotide nucleotidyltransferase 1, mitochondrial	87178	reviewed	Enzyme
Q8TD30	BXGT018805	Alanine aminotransferase 2	84706	reviewed	Enzyme
Q92794	BXGT019375	Histone acetyltransferase KAT6A	7994	reviewed	Enzyme
Q969G3	BXGT019607	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1	6605	reviewed
Q96C36	BXGT019631	Pyrroline-5-carboxylate reductase 2	29920	reviewed
Q96FE5	BXGT019657	Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1	84894	reviewed	Receptor
Q96IV0	BXGT019677	Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase	55768	reviewed	Enzyme
Q96PU5	BXGT019711	E3 ubiquitin-protein ligase NEDD4-like	23327	reviewed	Enzyme
Q96RE7	BXGT019725	Nucleus accumbens-associated protein 1	112939	reviewed
Q99250	BXGT019913	Sodium channel protein type 2 subunit alpha	6326	reviewed	Ion channel
Q9GZZ9	BXGT020430	Ubiquitin-like modifier-activating enzyme 5	79876	reviewed	Enzyme
Q9H4W6	BXGT020478	Transcription factor COE3	253738	reviewed
Q9H8M5	BXGT020496	Metal transporter CNNM2	54805	reviewed
Q9HA77	BXGT020504	Probable cysteine--tRNA ligase, mitochondrial	79587	reviewed	Enzyme
Q9HD42	BXGT020543	Charged multivesicular body protein 1a	5119	reviewed
Q9NS87	BXGT021201	Kinesin-like protein KIF15	56992	reviewed	Cellular structure
Q9NY46	BXGT021248	Sodium channel protein type 3 subunit alpha	6328	reviewed	Ion channel
Q9NY65	BXGT021252	Tubulin alpha-8 chain	51807	reviewed	Cellular structure
Q9UGM6	BXGT021687	Tryptophan--tRNA ligase, mitochondrial	10352	reviewed
Q9ULJ6	BXGT021761	Zinc finger MIZ domain-containing protein 1	57178	reviewed
Q9UPN3	BXGT021797	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5	23499	reviewed	Cellular structure
Q9UQD0	BXGT021811	Sodium channel protein type 8 subunit alpha	6334	reviewed	Ion channel
Q9UQM7	BXGT021814	Calcium/calmodulin-dependent protein kinase type II subunit alpha	815	reviewed	Kinase
Q9Y3C8	BXGT022256	Ubiquitin-fold modifier-conjugating enzyme 1	51506	reviewed
Q15878	BXGT022659	Voltage-dependent R-type calcium channel subunit alpha-1E	777	reviewed	Ion channel
Q9Y5W7	BXGT022783	Sorting nexin-14	57231	reviewed	Enzyme modulator
Q96C86	BXGT022803	m7GpppX diphosphatase	28960	reviewed	Enzyme
P51608	BXGT025073	Methyl-CpG-binding protein 2	4204	reviewed	Epigenetic regulator
Q05086	BXGT025648	Ubiquitin-protein ligase E3A	7337	reviewed
Q8WXI2	BXGT026145	Connector enhancer of kinase suppressor of ras 2	22866	reviewed
P09471	BXGT026153	Guanine nucleotide-binding protein G(o) subunit alpha	2775	reviewed	Enzyme modulator

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}