adisease

Showing entry for Talipes cavus

General Disease Information
BXGD Id	BXGD002806
Disease Name	Talipes cavus
Disease CUI Id	C0039273
MeSH Codes	C16 C05
Disease Class Name	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
Semantic Type	Anatomical Abnormality
Human Phenotype Ontology Id	HP:0040064
Human Phenotype Ontology Term	Abnormality of limbs
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00429	BXGT003919	Dynamin-1-like protein	10059	reviewed	Enzyme modulator
O00764	BXGT003948	Pyridoxal kinase	8566	reviewed	Kinase
O14832	BXGT004104	Phytanoyl-CoA dioxygenase, peroxisomal	5264	reviewed
O15269	BXGT004145	Serine palmitoyltransferase 1	10558	reviewed	Enzyme
O43323	BXGT004587	Desert hedgehog protein	50846	reviewed
O60313	BXGT004871	Dynamin-like 120 kDa protein, mitochondrial	4976	reviewed	Enzyme modulator
O75530	BXGT005135	Polycomb protein EED	8726	reviewed
O75923	BXGT005166	Dysferlin	8291	reviewed	Transporter
O95831	BXGT005399	Apoptosis-inducing factor 1, mitochondrial	9131	reviewed	Enzyme
P02545	BXGT005889	Prelamin-A/C	4000	reviewed
P02689	BXGT005919	Myelin P2 protein	5375	reviewed
P04062	BXGT006140	Lysosomal acid glucosylceramidase	2629	reviewed
P04792	BXGT006264	Heat shock protein beta-1	3315	reviewed
P05023	BXGT006294	Sodium/potassium-transporting ATPase subunit alpha-1	476	reviewed	Transporter
P06753	BXGT006498	Tropomyosin alpha-3 chain	7170	reviewed	Cellular structure
P07101	BXGT006547	Tyrosine 3-monooxygenase	7054	reviewed
P07384	BXGT006619	Calpain-1 catalytic subunit	823	reviewed	Enzyme
P07949	BXGT006703	Proto-oncogene tyrosine-protein kinase receptor Ret	5979	reviewed	Kinase
P08034	BXGT006716	Gap junction beta-1 protein	2705	reviewed	Cell-cell junction
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08473	BXGT006773	Neprilysin	4311	reviewed	Enzyme
P09936	BXGT006943	Ubiquitin carboxyl-terminal hydrolase isozyme L1	7345	reviewed	Enzyme
P10809	BXGT007617	60 kDa heat shock protein, mitochondrial	3329	reviewed
P11362	BXGT007693	Fibroblast growth factor receptor 1	2260	reviewed	Kinase
P12004	BXGT007766	Proliferating cell nuclear antigen	5111	reviewed	Nucleic acid binding
P12081	BXGT007772	Histidine--tRNA ligase, cytoplasmic	3035	reviewed	Enzyme
P13637	BXGT007933	Sodium/potassium-transporting ATPase subunit alpha-3	478	reviewed	Transporter
P21817	BXGT008693	Ryanodine receptor 1	6261	reviewed	Ion channel
P22304	BXGT008752	Iduronate 2-sulfatase	3423	reviewed
P23381	BXGT008860	Tryptophan--tRNA ligase, cytoplasmic	7453	reviewed	Enzyme
P28329	BXGT009251	Choline O-acetyltransferase	1103	reviewed	Enzyme
P29033	BXGT009308	Gap junction beta-2 protein	2706	reviewed	Cell-cell junction
P30793	BXGT009466	GTP cyclohydrolase 1	2643	reviewed	Enzyme
P32004	BXGT009594	Neural cell adhesion molecule L1	3897	reviewed
P35475	BXGT009837	Alpha-L-iduronidase	3425	reviewed	Enzyme
P35555	BXGT009845	Fibrillin-1	2200	reviewed	Calcium-binding protein
P41250	BXGT010244	Glycine--tRNA ligase	2617	reviewed	Enzyme
P48029	BXGT010606	Sodium- and chloride-dependent creatine transporter 1	6535	reviewed	Transporter
P49588	BXGT010713	Alanine--tRNA ligase, cytoplasmic	16	reviewed	Nucleic acid binding
P49638	BXGT010720	Alpha-tocopherol transfer protein	7274	reviewed	Transporter
P49773	BXGT010741	Histidine triad nucleotide-binding protein 1	3094	reviewed	Enzyme
P49959	BXGT010766	Double-strand break repair protein MRE11	4361	reviewed
P50542	BXGT010808	Peroxisomal targeting signal 1 receptor	5830	reviewed	Transporter
P51149	BXGT010835	Ras-related protein Rab-7a	7879	reviewed
P54098	BXGT011030	DNA polymerase subunit gamma-1	5428	reviewed	Enzyme
P54886	BXGT011092	Delta-1-pyrroline-5-carboxylate synthase	5832	reviewed	Enzyme
P55072	BXGT011103	Transitional endoplasmic reticulum ATPase	7415	reviewed
P60880	BXGT011335	Synaptosomal-associated protein 25	6616	reviewed	Transporter
P60891	BXGT011337	Ribose-phosphate pyrophosphokinase 1	5631	reviewed	Kinase
P68133	BXGT011578	Actin, alpha skeletal muscle	58	reviewed	Cellular structure
Q01453	BXGT012588	Peripheral myelin protein 22	5376	reviewed	Cellular structure
Q12840	BXGT013269	Kinesin heavy chain isoform 5A	3798	reviewed	Cellular structure
Q12879	BXGT013275	Glutamate receptor ionotropic, NMDA 2A	2903	reviewed	Ion channel
Q14204	BXGT013456	Cytoplasmic dynein 1 heavy chain 1	1778	reviewed	Enzyme
Q15022	BXGT013523	Polycomb protein SUZ12	23512	reviewed	Nucleic acid binding
Q15046	BXGT013527	Lysine--tRNA ligase	3735	reviewed	Enzyme
Q15120	BXGT013542	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial	5165	reviewed	Kinase
Q15907	BXGT013611	Ras-related protein Rab-11B	9230	reviewed
Q15910	BXGT013612	Histone-lysine N-methyltransferase EZH2	2146	reviewed	Epigenetic regulator
Q16595	BXGT013643	Frataxin, mitochondrial	2395	reviewed	Enzyme
Q16828	BXGT013676	Dual specificity protein phosphatase 6	1848	reviewed
Q7Z2E3	BXGT017246	Aprataxin	54840	reviewed	Nucleic acid binding
Q8NI60	BXGT018572	Atypical kinase COQ8A, mitochondrial	56997	reviewed	Kinase
Q8WXF7	BXGT019011	Atlastin-1	51062	reviewed	Enzyme modulator
Q8WZ42	BXGT019023	Titin	7273	reviewed	Kinase
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q96T60	BXGT019745	Bifunctional polynucleotide phosphatase/kinase	11284	reviewed
Q99653	BXGT019945	Calcineurin B homologous protein 1	11261	reviewed
Q99720	BXGT019955	Sigma non-opioid intracellular receptor 1	10280	reviewed
Q9BY41	BXGT020180	Histone deacetylase 8	55869	reviewed	Epigenetic regulator
Q9GZV3	BXGT020427	High affinity choline transporter 1	60482	reviewed	Transporter
Q9HBA0	BXGT020516	Transient receptor potential cation channel subfamily V member 4	59341	reviewed	Ion channel
Q9HCG7	BXGT020533	Non-lysosomal glucosylceramidase	57704	reviewed
Q9HD42	BXGT020543	Charged multivesicular body protein 1a	5119	reviewed
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	55775	reviewed	Enzyme
Q9NW15	BXGT021229	Anoctamin-10	55129	reviewed
Q9NZJ4	BXGT021274	Sacsin	26278	reviewed
Q9Y6X9	BXGT022345	ATPase MORC2	22880	reviewed
P43146	BXGT022852	Netrin receptor DCC	1630	reviewed
Q9UBP0	BXGT023601	Spastin	6683	reviewed	Cellular structure
O95140	BXGT024482	Mitofusin-2	9927	reviewed	Enzyme
Q96L73	BXGT024676	Histone-lysine N-methyltransferase, H3 lysine-36 specific	64324	reviewed	Epigenetic regulator
P51608	BXGT025073	Methyl-CpG-binding protein 2	4204	reviewed	Epigenetic regulator

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}