Showing entry for Histone H3.1t


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013657
Protein NameHistone H3.1t
Uniport IdQ16695
GeneH3-4
Gene Id8290
DomainHistone
Pfam PF00125  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
6. Human Diseases 6.5 Substance dependence hsa05034 Alcoholism
6. Human Diseases 6.1 Cancers: Overview hsa05202 Transcriptional misregulation in cancer
6. Human Diseases 6.3 Immune diseases hsa05322 Systemic lupus erythematosus
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006303 double-strand break repair via nonhomologous end joining
Biological Process GO:0006334 nucleosome assembly
Biological Process GO:0016233 telomere capping
molecular function GO:0003677 DNA binding
molecular function GO:0046982 protein heterodimerization activity
cellular component GO:0070062 extracellular exosome
cellular component GO:0000784 nuclear chromosome, telomeric region
cellular component GO:0000788 nuclear nucleosome
cellular component GO:0005654 nucleoplasm
cellular component GO:0000786 nucleosome
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-110328 Recognition and association of DNA glycosylase with site containing an affected pyrimidine
R-HSA-110329 Cleavage of the damaged pyrimidine
R-HSA-110330 Recognition and association of DNA glycosylase with site containing an affected purine
R-HSA-110330 Recognition and association of DNA glycosylase with site containing an affected purine
R-HSA-110331 Cleavage of the damaged purine
R-HSA-110331 Cleavage of the damaged purine
R-HSA-1221632 Meiotic synapsis
R-HSA-1474165 Reproduction
R-HSA-1500620 Meiosis
R-HSA-157579 Telomere Maintenance
R-HSA-162582 Signal Transduction
R-HSA-162582 Signal Transduction
R-HSA-1640170 Cell Cycle
R-HSA-1640170 Cell Cycle
R-HSA-171306 Packaging Of Telomere Ends
R-HSA-195721 Signaling by WNT
R-HSA-195721 Signaling by WNT
R-HSA-201681 TCF dependent signaling in response to WNT
R-HSA-201681 TCF dependent signaling in response to WNT
R-HSA-201722 Formation of the beta-catenin:TCF transactivating complex
R-HSA-201722 Formation of the beta-catenin:TCF transactivating complex
R-HSA-2262752 Cellular responses to stress
R-HSA-2299718 Condensation of Prophase Chromosomes
R-HSA-2559583 Cellular Senescence
R-HSA-2559586 DNA Damage/Telomere Stress Induced Senescence
R-HSA-5693532 DNA Double-Strand Break Repair
R-HSA-5693538 Homology Directed Repair
R-HSA-5693565 Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
R-HSA-5693567 HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)
R-HSA-5693571 Nonhomologous End-Joining (NHEJ)
R-HSA-5693606 DNA Double Strand Break Response
R-HSA-5693607 Processing of DNA double-strand break ends
R-HSA-68875 Mitotic Prophase
R-HSA-68886 M Phase
R-HSA-69278 Cell Cycle, Mitotic
R-HSA-69473 G2/M DNA damage checkpoint
R-HSA-69481 G2/M Checkpoints
R-HSA-69620 Cell Cycle Checkpoints
R-HSA-73884 Base Excision Repair
R-HSA-73884 Base Excision Repair
R-HSA-73886 Chromosome Maintenance
R-HSA-73894 DNA Repair
R-HSA-73894 DNA Repair
R-HSA-73927 Depurination
R-HSA-73927 Depurination
R-HSA-73928 Depyrimidination
R-HSA-73929 Base-Excision Repair, AP Site Formation
R-HSA-73929 Base-Excision Repair, AP Site Formation
R-HSA-8953897 Cellular responses to external stimuli
R-HSA-912446 Meiotic recombination
R-HSA-9670095 Inhibition of DNA recombination at telomere
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004509 BXGD000275 Azoospermia Male Urogenital Diseases
C0004681 BXGD000286 Bagassosis Respiratory Tract Diseases; Occupational Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007131 BXGD000441 Non-Small Cell Lung Carcinoma Neoplasms; Respiratory Tract Diseases
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0016412 BXGD001058 Folic Acid Deficiency Nutritional and Metabolic Diseases
C0020796 BXGD001468 Profound Mental Retardation Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0025363 BXGD001867 Mental Retardation, Psychosocial Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0027613 BXGD002004 Neonatal hepatitis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Infections
C0027651 BXGD002009 Neoplasms Neoplasms
C0032273 BXGD002343 Pneumoconiosis Respiratory Tract Diseases; Occupational Diseases
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0034069 BXGD002458 Pulmonary Fibrosis Respiratory Tract Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0278601 BXGD006547 Inflammatory Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0549493 BXGD009385 Alveolitis Skin and Connective Tissue Diseases; Respiratory Tract Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0747845 BXGD010184 early pregnancy
C0917816 BXGD011419 Mental deficiency Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C1266025 BXGD011935 Traditional Serrated Adenoma Neoplasms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C2986658 BXGD018234 Diffuse Intrinsic Pontine Glioma
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C4289688 BXGD022493 Diffuse midline glioma, point mutation K27M in histone H3 Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein