adisease

Showing entry for Azoospermia

General Disease Information
BXGD Id	BXGD000275
Disease Name	Azoospermia
Disease CUI Id	C0004509
MeSH Codes	C12
Disease Class Name	Male Urogenital Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0000119
Human Phenotype Ontology Term	Abnormality of the genitourinary system
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00401	BXGT003915	Neural Wiskott-Aldrich syndrome protein	8976	reviewed	Cellular structure
O00444	BXGT003921	Serine/threonine-protein kinase PLK4	10733	reviewed	Kinase
O15455	BXGT004171	Toll-like receptor 3	7098	reviewed	Receptor
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O60760	BXGT004899	Hematopoietic prostaglandin D synthase	27306	reviewed
O75223	BXGT005106	Gamma-glutamylcyclotransferase	79017	reviewed
O75604	BXGT005139	Ubiquitin carboxyl-terminal hydrolase 2	9099	reviewed	Enzyme
P01275	BXGT005747	Glucagon	2641	reviewed
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P02786	BXGT005961	Transferrin receptor protein 1	7037	reviewed	Enzyme
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P04150	BXGT006154	Glucocorticoid receptor	2908	reviewed	Nuclear receptor
P04181	BXGT006165	Ornithine aminotransferase, mitochondrial	4942	reviewed	Enzyme
P05154	BXGT006327	Plasma serine protease inhibitor	5104	reviewed	Enzyme modulator
P05187	BXGT006339	Alkaline phosphatase, placental type	250	reviewed	Enzyme
P06870	BXGT006518	Kallikrein-1	3816	reviewed	Enzyme
P07205	BXGT006568	Phosphoglycerate kinase 2	5232	reviewed	Kinase
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P08684	BXGT006812	Cytochrome P450 3A4	1576	reviewed	Enzyme
P08842	BXGT006830	Steryl-sulfatase	412	reviewed	Enzyme
P09211	BXGT006869	Glutathione S-transferase P	2950	reviewed
P09488	BXGT006899	Glutathione S-transferase Mu 1	2944	reviewed
P09601	BXGT006909	Heme oxygenase 1	3162	reviewed
P09923	BXGT006942	Intestinal-type alkaline phosphatase	248	reviewed	Enzyme
P10275	BXGT007552	Androgen receptor	367	reviewed	Nuclear receptor
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10721	BXGT007605	Mast/stem cell growth factor receptor Kit	3815	reviewed	Kinase
P10828	BXGT007624	Thyroid hormone receptor beta	7068	reviewed	Nuclear receptor
P10997	BXGT007643	Islet amyloid polypeptide	3375	reviewed	Signaling
P12004	BXGT007766	Proliferating cell nuclear antigen	5111	reviewed	Nucleic acid binding
P12643	BXGT007830	Bone morphogenetic protein 2	650	reviewed	Signaling
P13569	BXGT007923	Cystic fibrosis transmembrane conductance regulator	1080	reviewed	Ion channel
P16070	BXGT008186	CD44 antigen	960	reviewed
P16157	BXGT008203	Ankyrin-1	286	reviewed
P18074	BXGT008374	General transcription and DNA repair factor IIH helicase subunit XPD	2068	reviewed	Enzyme
P18887	BXGT008437	DNA repair protein XRCC1	7515	reviewed
P19544	BXGT008494	Wilms tumor protein	7490	reviewed	Nucleic acid binding
P21583	BXGT008667	Kit ligand	4254	reviewed
P22607	BXGT008784	Fibroblast growth factor receptor 3	2261	reviewed	Kinase
P23945	BXGT008931	Follicle-stimulating hormone receptor	2492	reviewed	G-protein coupled receptor
P24941	BXGT009002	Cyclin-dependent kinase 2	1017	reviewed	Kinase
P25440	BXGT009044	Bromodomain-containing protein 2	6046	reviewed	Epigenetic regulator
P26358	BXGT009104	DNA (cytosine-5)-methyltransferase 1	1786	reviewed	Epigenetic regulator
P27361	BXGT009176	Mitogen-activated protein kinase 3	5595	reviewed	Kinase
P29474	BXGT009352	Nitric oxide synthase, endothelial	4846	reviewed
P30711	BXGT009460	Glutathione S-transferase theta-1	2952	reviewed
P31213	BXGT009515	3-oxo-5-alpha-steroid 4-dehydrogenase 2	6716	reviewed	Enzyme
P31260	BXGT009519	Homeobox protein Hox-A10	3206	reviewed
P33527	BXGT009728	Multidrug resistance-associated protein 1	4363	reviewed	Transporter
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	672	reviewed	Enzyme
P40692	BXGT010195	DNA mismatch repair protein Mlh1	4292	reviewed	Nucleic acid binding
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P42658	BXGT010327	Dipeptidyl aminopeptidase-like protein 6	1804	reviewed	Enzyme
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P48023	BXGT010604	Tumor necrosis factor ligand superfamily member 6	356	reviewed	Signaling
P51843	BXGT010897	Nuclear receptor subfamily 0 group B member 1	190	reviewed	Nuclear receptor
P52209	BXGT010923	6-phosphogluconate dehydrogenase, decarboxylating	5226	reviewed	Enzyme
P52756	BXGT010950	RNA-binding protein 5	10181	reviewed
P54132	BXGT011032	Bloom syndrome protein	641	reviewed
P54278	BXGT011038	Mismatch repair endonuclease PMS2	5395	reviewed	Nucleic acid binding
P54289	BXGT011040	Voltage-dependent calcium channel subunit alpha-2/delta-1	781	reviewed	Ion channel
P54652	BXGT011064	Heat shock-related 70 kDa protein 2	3306	reviewed
P62834	BXGT011464	Ras-related protein Rap-1A	5906	reviewed	Enzyme modulator
P63146	BXGT011504	Ubiquitin-conjugating enzyme E2 B	7320	reviewed
P78396	BXGT011842	Cyclin-A1	8900	reviewed	Enzyme modulator
P98170	BXGT012231	E3 ubiquitin-protein ligase XIAP	331	reviewed	Enzyme modulator
Q01718	BXGT012609	Adrenocorticotropic hormone receptor	4158	reviewed	G-protein coupled receptor
Q01831	BXGT012621	DNA repair protein complementing XP-C cells	7508	reviewed	Nucleic acid binding
Q01968	BXGT012626	Inositol polyphosphate 5-phosphatase OCRL-1	4952	reviewed	Enzyme
Q02790	BXGT012672	Peptidyl-prolyl cis-trans isomerase FKBP4	2288	reviewed	Enzyme
Q03933	BXGT012740	Heat shock factor protein 2	3298	reviewed	Transcription factor
Q06609	BXGT012884	DNA repair protein RAD51 homolog 1	5888	reviewed
Q08722	BXGT013002	Leukocyte surface antigen CD47	961	reviewed
Q09013	BXGT013023	Myotonin-protein kinase	1760	reviewed	Kinase
Q13233	BXGT013330	Mitogen-activated protein kinase kinase kinase 1	4214	reviewed	Kinase
Q13285	BXGT013335	Steroidogenic factor 1	2516	reviewed	Nuclear receptor
Q13423	BXGT013352	NAD(P) transhydrogenase, mitochondrial	23530	reviewed	Enzyme
Q15831	BXGT013604	Serine/threonine-protein kinase STK11	6794	reviewed	Kinase
Q16695	BXGT013657	Histone H3.1t	8290	reviewed
Q30201	BXGT014297	Hereditary hemochromatosis protein	3077	reviewed
Q658P3	BXGT016142	Metalloreductase STEAP3	55240	reviewed
Q6PCD5	BXGT016464	E3 ubiquitin-protein ligase RFWD3	55159	reviewed	Enzyme
Q6ZVN8	BXGT016641	Hemojuvelin	148738	reviewed
Q86W24	BXGT017622	NACHT, LRR and PYD domains-containing protein 14	338323	reviewed
Q86YC2	BXGT017633	Partner and localizer of BRCA2	79728	reviewed
Q8IWB6	BXGT018354	Inactive serine/threonine-protein kinase TEX14	56155	reviewed	Kinase
Q8IYD8	BXGT018367	Fanconi anemia group M protein	57697	reviewed	Enzyme
Q8NHU6	BXGT018569	Tudor domain-containing protein 7	23424	reviewed	Enzyme
Q99707	BXGT019952	Methionine synthase	4548	reviewed
Q9BW62	BXGT020149	Katanin p60 ATPase-containing subunit A-like 1	84056	reviewed	Cellular structure
Q9BY66	BXGT020183	Lysine-specific demethylase 5D	8284	reviewed	Transcription factor
Q9BZ23	BXGT020194	Pantothenate kinase 2, mitochondrial	80025	reviewed	Kinase
Q9HD26	BXGT020540	Golgi-associated PDZ and coiled-coil motif-containing protein	57120	reviewed
Q9NNW7	BXGT021139	Thioredoxin reductase 2, mitochondrial	10587	reviewed	Enzyme
Q9NPD8	BXGT021152	Ubiquitin-conjugating enzyme E2 T	29089	reviewed
Q9NPI8	BXGT021161	Fanconi anemia group F protein	2188	reviewed
Q9NW38	BXGT021230	E3 ubiquitin-protein ligase FANCL	55120	reviewed	Enzyme
Q9UBK8	BXGT021655	Methionine synthase reductase	4552	reviewed
Q9UGN5	BXGT021688	Poly [ADP-ribose] polymerase 2	10038	reviewed
Q9UHI8	BXGT021701	A disintegrin and metalloproteinase with thrombospondin motifs 1	9510	reviewed	Enzyme
Q9UHL0	BXGT021702	ATP-dependent RNA helicase DDX25	29118	reviewed
Q9UI95	BXGT021714	Mitotic spindle assembly checkpoint protein MAD2B	10459	reviewed
Q9UJW3	BXGT021732	DNA (cytosine-5)-methyltransferase 3-like	29947	reviewed
Q9UNA0	BXGT021784	A disintegrin and metalloproteinase with thrombospondin motifs 5	11096	reviewed	Enzyme
Q9Y6F8	BXGT022329	Testis-specific chromodomain protein Y 1	9085	reviewed
Q96QC4	BXGT023878	MHC class I polypeptide-related sequence A	100507436	unreviewed
Q8IYM1	BXGT024860	Septin-12	124404	reviewed	Enzyme modulator

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}