Showing entry for Diffuse Intrinsic Pontine Glioma


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD018234
Disease NameDiffuse Intrinsic Pontine Glioma
Disease CUI IdC2986658
MeSH Codes   
Disease Class Name
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00255 BXGT003903 Menin 4221 reviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O15054 BXGT004121 Lysine-specific demethylase 6B 23135 reviewed Epigenetic regulator
O15118 BXGT004127 NPC intracellular cholesterol transporter 1 4864 reviewed Transporter
O15297 BXGT004149 Protein phosphatase 1D 8493 reviewed Enzyme
O75530 BXGT005135 Polycomb protein EED 8726 reviewed
O96017 BXGT005415 Serine/threonine-protein kinase Chk2 11200 reviewed Kinase
P04629 BXGT006239 High affinity nerve growth factor receptor 4914 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08575 BXGT006793 Receptor-type tyrosine-protein phosphatase C 5788 reviewed Enzyme
P09874 BXGT006934 Poly [ADP-ribose] polymerase 1 142 reviewed
P10909 BXGT007630 Clusterin 1191 reviewed
P11802 BXGT007750 Cyclin-dependent kinase 4 1019 reviewed Kinase
P13639 BXGT007934 Elongation factor 2 1938 reviewed Enzyme
P14416 BXGT008011 D(2) dopamine receptor 1813 reviewed G-protein coupled receptor
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16234 BXGT008209 Platelet-derived growth factor receptor alpha 5156 reviewed Kinase
P19544 BXGT008494 Wilms tumor protein 7490 reviewed Nucleic acid binding
P28223 BXGT009239 5-hydroxytryptamine receptor 2A 3356 reviewed G-protein coupled receptor
P29375 BXGT009338 Lysine-specific demethylase 5A 5927 reviewed
P30291 BXGT009417 Wee1-like protein kinase 7465 reviewed Kinase
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P50613 BXGT010815 Cyclin-dependent kinase 7 1022 reviewed Kinase
P53350 BXGT010984 Serine/threonine-protein kinase PLK1 5347 reviewed Kinase
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P62942 BXGT011474 Peptidyl-prolyl cis-trans isomerase FKBP1A 2280 reviewed Enzyme
P68431 BXGT011601 Histone H3.1 8968 reviewed
P84243 BXGT012052 Histone H3.3 3021 reviewed
Q00534 BXGT012533 Cyclin-dependent kinase 6 1021 reviewed Kinase
Q04771 BXGT012783 Activin receptor type-1 90 reviewed Kinase
Q13255 BXGT013332 Metabotropic glutamate receptor 1 2911 reviewed G-protein coupled receptor
Q14627 BXGT013492 Interleukin-13 receptor subunit alpha-2 3598 reviewed Signaling
Q14680 BXGT013499 Maternal embryonic leucine zipper kinase 9833 reviewed Kinase
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q16695 BXGT013657 Histone H3.1t 8290 reviewed
Q8IV63 BXGT018341 Inactive serine/threonine-protein kinase VRK3 51231 reviewed Kinase
Q9UBB5 BXGT021649 Methyl-CpG-binding domain protein 2 8932 reviewed Epigenetic regulator
Q9UKV0 BXGT021750 Histone deacetylase 9 9734 reviewed Epigenetic regulator
Q9UNQ0 BXGT021792 ATP-binding cassette sub-family G member 2 9429 reviewed Transporter
P16104 BXGT024571 Histone H2AX 3014 reviewed Nucleic acid binding
Q12888 BXGT024878 TP53-binding protein 1 7158 reviewed Epigenetic regulator
Q13635 BXGT024910 Protein patched homolog 1 5727 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease