adisease

Showing entry for Mental deficiency

General Disease Information
BXGD Id	BXGD011419
Disease Name	Mental deficiency
Disease CUI Id	C0917816
MeSH Codes	C23 C10 F03 F01
Disease Class Name	Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
Semantic Type	Mental or Behavioral Dysfunction
Human Phenotype Ontology Id	HP:0000707
Human Phenotype Ontology Term	Abnormality of the nervous system
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00189	BXGT003891	AP-4 complex subunit mu-1	9179	reviewed	Extracellular structure
O00330	BXGT003910	Pyruvate dehydrogenase protein X component, mitochondrial	8050	reviewed	Enzyme
O15054	BXGT004121	Lysine-specific demethylase 6B	23135	reviewed	Epigenetic regulator
O15305	BXGT004152	Phosphomannomutase 2	5373	reviewed	Enzyme
O43497	BXGT004596	Voltage-dependent T-type calcium channel subunit alpha-1G	8913	reviewed	Ion channel
P05129	BXGT006322	Protein kinase C gamma type	5582	reviewed	Kinase
P06865	BXGT006516	Beta-hexosaminidase subunit alpha	3073	reviewed	Enzyme
P07101	BXGT006547	Tyrosine 3-monooxygenase	7054	reviewed
P09874	BXGT006934	Poly [ADP-ribose] polymerase 1	142	reviewed
P11166	BXGT007661	Solute carrier family 2, facilitated glucose transporter member 1	6513	reviewed	Transporter
P15328	BXGT008108	Folate receptor alpha	2348	reviewed
P16389	BXGT008221	Potassium voltage-gated channel subfamily A member 2	3737	reviewed	Ion channel
P18089	BXGT008379	Alpha-2B adrenergic receptor	151	reviewed	G-protein coupled receptor
P20248	BXGT008554	Cyclin-A2	890	reviewed	Enzyme modulator
P21359	BXGT008640	Neurofibromin	4763	reviewed	Enzyme modulator
P21802	BXGT008691	Fibroblast growth factor receptor 2	2263	reviewed	Kinase
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P29375	BXGT009338	Lysine-specific demethylase 5A	5927	reviewed
P31645	BXGT009558	Sodium-dependent serotonin transporter	6532	reviewed	Transporter
P32004	BXGT009594	Neural cell adhesion molecule L1	3897	reviewed
P34130	BXGT009752	Neurotrophin-4	4909	reviewed	Signaling
P35219	BXGT009797	Carbonic anhydrase-related protein	767	reviewed
P35498	BXGT009838	Sodium channel protein type 1 subunit alpha	6323	reviewed	Ion channel
P39060	BXGT010088	Collagen alpha-1(XVIII) chain	80781	reviewed
P41229	BXGT010239	Lysine-specific demethylase 5C	8242	reviewed
P42575	BXGT010318	Caspase-2	835	reviewed	Enzyme
P49327	BXGT010694	Fatty acid synthase	2194	reviewed	Enzyme
P49802	BXGT010746	Regulator of G-protein signaling 7	6000	reviewed
P51649	BXGT010872	Succinate-semialdehyde dehydrogenase, mitochondrial	7915	reviewed	Enzyme
P54802	BXGT011081	Alpha-N-acetylglucosaminidase	4669	reviewed
P55263	BXGT011115	Adenosine kinase	132	reviewed	Kinase
P56524	BXGT011176	Histone deacetylase 4	9759	reviewed	Epigenetic regulator
P58400	BXGT011235	Neurexin-1-beta	9378	reviewed
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P63092	BXGT011495	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	2778	reviewed
Q06787	BXGT012890	Synaptic functional regulator FMR1	2332	reviewed	Nucleic acid binding
Q13224	BXGT013328	Glutamate receptor ionotropic, NMDA 2B	2904	reviewed	Ion channel
Q14204	BXGT013456	Cytoplasmic dynein 1 heavy chain 1	1778	reviewed	Enzyme
Q14353	BXGT013463	Guanidinoacetate N-methyltransferase	2593	reviewed
Q16695	BXGT013657	Histone H3.1t	8290	reviewed
Q2M1P5	BXGT014129	Kinesin-like protein KIF7	374654	reviewed
Q4G0J3	BXGT014809	La-related protein 7	51574	reviewed	Nucleic acid binding
Q7Z3B3	BXGT017249	KAT8 regulatory NSL complex subunit 1	284058	reviewed
Q8NEM0	BXGT018555	Microcephalin	79648	reviewed	Nucleic acid binding
Q8WWQ0	BXGT019003	PH-interacting protein	55023	reviewed	Epigenetic regulator
Q99986	BXGT019980	Serine/threonine-protein kinase VRK1	7443	reviewed	Kinase
Q9BXJ9	BXGT020170	N-alpha-acetyltransferase 15, NatA auxiliary subunit	80155	reviewed	Enzyme
Q9BY49	BXGT020181	Peroxisomal trans-2-enoyl-CoA reductase	55825	reviewed	Enzyme
Q9H8P0	BXGT020497	Polyprenol reductase	79644	reviewed
Q9NRR6	BXGT021193	Phosphatidylinositol polyphosphate 5-phosphatase type IV	56623	reviewed
Q9UKM7	BXGT021747	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase	11253	reviewed	Chaperone
Q9UQD0	BXGT021811	Sodium channel protein type 8 subunit alpha	6334	reviewed	Ion channel
Q9Y6K1	BXGT022331	DNA (cytosine-5)-methyltransferase 3A	1788	reviewed
Q9Y5W7	BXGT022783	Sorting nexin-14	57231	reviewed	Enzyme modulator
P43146	BXGT022852	Netrin receptor DCC	1630	reviewed
P25054	BXGT022961	Adenomatous polyposis coli protein	324	reviewed
Q9UBP0	BXGT023601	Spastin	6683	reviewed	Cellular structure
Q96L73	BXGT024676	Histone-lysine N-methyltransferase, H3 lysine-36 specific	64324	reviewed	Epigenetic regulator
P51608	BXGT025073	Methyl-CpG-binding protein 2	4204	reviewed	Epigenetic regulator
Q96DA2	BXGT025522	Ras-related protein Rab-39B	116442	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}