Showing entry for Kynurenine--oxoglutarate transaminase 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013667
Protein NameKynurenine--oxoglutarate transaminase 1
Uniport IdQ16773
GeneKYAT1
Gene Id883
DomainAminotran_1_2
Pfam PF00155  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
1. Metabolism 1.5 Amino acid metabolism hsa00270 Cysteine and methionine metabolism
1. Metabolism 1.5 Amino acid metabolism hsa00380 Tryptophan metabolism
1. Metabolism 1.6 Metabolism of other amino acids hsa00450 Selenocompound metabolism
1. Metabolism 1.0 Global and overview maps hsa01100 Metabolic pathways
6. Human Diseases 6.1 Cancers: Overview hsa05204 Chemical carcinogenesis
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0008652 cellular amino acid biosynthetic process
Biological Process GO:0006575 cellular modified amino acid metabolic process
Biological Process GO:0070189 kynurenine metabolic process
Biological Process GO:0097053 L-kynurenine catabolic process
Biological Process GO:0006559 L-phenylalanine catabolic process
Biological Process GO:0006569 tryptophan catabolic process
molecular function GO:0047804 cysteine-S-conjugate beta-lyase activity
molecular function GO:0047316 glutamine-phenylpyruvate transaminase activity
molecular function GO:0016212 kynurenine-oxoglutarate transaminase activity
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0030170 pyridoxal phosphate binding
molecular function GO:0008483 transaminase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005739 mitochondrion
Reactome
Pathway Id Pathway Name
R-HSA-1430728 Metabolism
R-HSA-71240 Tryptophan catabolism
R-HSA-71291 Metabolism of amino acids and derivatives
R-HSA-8963691 Phenylalanine and tyrosine metabolism
R-HSA-8964208 Phenylalanine metabolism
R-HSA-8964539 Glutamate and glutamine metabolism
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0010346 BXGD000664 Crohn Disease Digestive System Diseases
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0020473 BXGD001396 Hyperlipidemia Nutritional and Metabolic Diseases
C0021390 BXGD001503 Inflammatory Bowel Diseases Digestive System Diseases
C0022665 BXGD001573 Kidney Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0205696 BXGD004107 Anaplastic carcinoma Neoplasms
C0205697 BXGD004108 Carcinoma, Spindle-Cell Neoplasms
C0205698 BXGD004109 Undifferentiated carcinoma Neoplasms
C0205699 BXGD004110 Carcinomatosis Neoplasms
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0346388 BXGD007819 Malignant melanoma of choroid Neoplasms; Eye Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0740457 BXGD010000 Malignant neoplasm of kidney Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0877008 BXGD011325 Enzyme inhibition disorder
C1263846 BXGD011897 Attention deficit hyperactivity disorder Mental Disorders
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1527304 BXGD013266 Allergic Reaction Immune System Diseases
C1861172 BXGD016016 Venous Thromboembolism Cardiovascular Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0000557 1H-Indole-3-acetic acid 175.18
BXGC0000565 1H-Indole-3-propanoic acid 189.21
BXGC0001623 L-Tryptophan 204.23
BXGC0003214 L-(-)-Phenylalanine 165.19
BXGC0015497 D-phenylalanine 165.08
BXGC0030267 S-ethylcysteine 149.05
BXGC0034206 pyridoxamine phosphate 248.06
BXGC0043088 Pyridoxal Phosphate 247.02
BXGC0047334 (2R)-2-Amino-3-Methylselanylpropanoic Acid 182.98
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein