Showing entry for Enzyme inhibition disorder


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD011325
Disease NameEnzyme inhibition disorder
Disease CUI IdC0877008
MeSH Codes   
Disease Class Name
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O00519 BXGT003934 Fatty-acid amide hydrolase 1 2166 reviewed
O14757 BXGT004092 Serine/threonine-protein kinase Chk1 1111 reviewed Kinase
O43451 BXGT004594 Maltase-glucoamylase, intestinal 8972 reviewed Enzyme
O75164 BXGT005104 Lysine-specific demethylase 4A 9682 reviewed
O76074 BXGT005174 cGMP-specific 3',5'-cyclic phosphodiesterase 8654 reviewed
O94925 BXGT005342 Glutaminase kidney isoform, mitochondrial 2744 reviewed Enzyme
O96013 BXGT005414 Serine/threonine-protein kinase PAK 4 10298 reviewed Kinase
P00325 BXGT005498 Alcohol dehydrogenase 1B 125 reviewed Enzyme
P00326 BXGT005499 Alcohol dehydrogenase 1C 126 reviewed Enzyme
P00374 BXGT005520 Dihydrofolate reductase 1719 reviewed Enzyme
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00739 BXGT005633 Haptoglobin-related protein 3250 reviewed Enzyme
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P00918 BXGT005690 Carbonic anhydrase 2 760 reviewed
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01034 BXGT005721 Cystatin-C 1471 reviewed
P01189 BXGT005742 Pro-opiomelanocortin 5443 reviewed
P01270 BXGT005746 Parathyroid hormone 5741 reviewed
P04004 BXGT006125 Vitronectin 7448 reviewed
P04049 BXGT006133 RAF proto-oncogene serine/threonine-protein kinase 5894 reviewed Kinase
P04054 BXGT006136 Phospholipase A2 5319 reviewed Enzyme
P05093 BXGT006313 Steroid 17-alpha-hydroxylase/17,20 lyase 1586 reviewed
P05108 BXGT006317 Cholesterol side-chain cleavage enzyme, mitochondrial 1583 reviewed
P05177 BXGT006336 Cytochrome P450 1A2 1544 reviewed Enzyme
P05187 BXGT006339 Alkaline phosphatase, placental type 250 reviewed Enzyme
P06276 BXGT006430 Cholinesterase 590 reviewed
P06731 BXGT006488 Carcinoembryonic antigen-related cell adhesion molecule 5 1048 reviewed
P06858 BXGT006515 Lipoprotein lipase 4023 reviewed Enzyme
P07327 BXGT006598 Alcohol dehydrogenase 1A 124 reviewed Enzyme
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08319 BXGT006764 Alcohol dehydrogenase 4 127 reviewed Enzyme
P08473 BXGT006773 Neprilysin 4311 reviewed Enzyme
P08684 BXGT006812 Cytochrome P450 3A4 1576 reviewed Enzyme
P09874 BXGT006934 Poly [ADP-ribose] polymerase 1 142 reviewed
P09917 BXGT006941 Arachidonate 5-lipoxygenase 240 reviewed Enzyme
P10635 BXGT007595 Cytochrome P450 2D6 1565 reviewed
P11388 BXGT007697 DNA topoisomerase 2-alpha 7153 reviewed
P11511 BXGT007717 Aromatase 1588 reviewed Enzyme
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P14324 BXGT008005 Farnesyl pyrophosphate synthase 2224 reviewed Enzyme
P14410 BXGT008009 Sucrase-isomaltase, intestinal 6476 reviewed Enzyme
P14550 BXGT008019 Aldo-keto reductase family 1 member A1 10327 reviewed Enzyme
P14555 BXGT008020 Phospholipase A2, membrane associated 5320 reviewed Enzyme
P14679 BXGT008039 Tyrosinase 7299 reviewed Enzyme
P14735 BXGT008042 Insulin-degrading enzyme 3416 reviewed Enzyme
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P14902 BXGT008065 Indoleamine 2,3-dioxygenase 1 3620 reviewed
P15104 BXGT008081 Glutamine synthetase 2752 reviewed Enzyme
P15121 BXGT008083 Aldo-keto reductase family 1 member B1 231 reviewed Enzyme
P15538 BXGT008137 Cytochrome P450 11B1, mitochondrial 1584 reviewed
P15559 BXGT008139 NAD(P)H dehydrogenase [quinone] 1 1728 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P17174 BXGT008289 Aspartate aminotransferase, cytoplasmic 2805 reviewed
P18031 BXGT008369 Tyrosine-protein phosphatase non-receptor type 1 5770 reviewed
P20813 BXGT008603 Cytochrome P450 2B6 1555 reviewed
P21397 BXGT008644 Amine oxidase [flavin-containing] A 4128 reviewed
P21589 BXGT008669 5'-nucleotidase 4907 reviewed Enzyme
P21964 BXGT008714 Catechol O-methyltransferase 1312 reviewed Enzyme
P22303 BXGT008751 Acetylcholinesterase 43 reviewed Enzyme
P22309 BXGT008753 UDP-glucuronosyltransferase 1-1 54658 reviewed
P23219 BXGT008837 Prostaglandin G/H synthase 1 5742 reviewed Enzyme
P24941 BXGT009002 Cyclin-dependent kinase 2 1017 reviewed Kinase
P27169 BXGT009161 Serum paraoxonase/arylesterase 1 5444 reviewed
P27338 BXGT009172 Amine oxidase [flavin-containing] B 4129 reviewed
P28332 BXGT009253 Alcohol dehydrogenase 6 130 reviewed Enzyme
P28676 BXGT009284 Grancalcin 25801 reviewed
P28845 BXGT009297 Corticosteroid 11-beta-dehydrogenase isozyme 1 3290 reviewed
P29375 BXGT009338 Lysine-specific demethylase 5A 5927 reviewed
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P30556 BXGT009441 Type-1 angiotensin II receptor 185 reviewed G-protein coupled receptor
P32754 BXGT009664 4-hydroxyphenylpyruvate dioxygenase 3242 reviewed Enzyme
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35557 BXGT009846 Glucokinase 2645 reviewed Kinase
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P36551 BXGT009927 Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial 1371 reviewed Enzyme
P37268 BXGT009975 Squalene synthase 2222 reviewed
P37840 BXGT010015 Alpha-synuclein 6622 reviewed Transporter
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P45452 BXGT010462 Collagenase 3 4322 reviewed Enzyme
P47712 BXGT010577 Cytosolic phospholipase A2 5321 reviewed Enzyme
P48147 BXGT010620 Prolyl endopeptidase 5550 reviewed Enzyme
P48506 BXGT010635 Glutamate--cysteine ligase catalytic subunit 2729 reviewed Enzyme
P48637 BXGT010649 Glutathione synthetase 2937 reviewed Enzyme
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49841 BXGT010750 Glycogen synthase kinase-3 beta 2932 reviewed Kinase
P51160 BXGT010840 Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' 5146 reviewed
P56945 BXGT011206 Breast cancer anti-estrogen resistance protein 1 9564 reviewed
P60891 BXGT011337 Ribose-phosphate pyrophosphokinase 1 5631 reviewed Kinase
P61006 BXGT011345 Ras-related protein Rab-8A 4218 reviewed
P78536 BXGT011847 Disintegrin and metalloproteinase domain-containing protein 17 6868 reviewed
Q02083 BXGT012633 N-acylethanolamine-hydrolyzing acid amidase 27163 reviewed Enzyme
Q02127 BXGT012635 Dihydroorotate dehydrogenase (quinone), mitochondrial 1723 reviewed Enzyme
Q06187 BXGT012860 Tyrosine-protein kinase BTK 695 reviewed Kinase
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q13427 BXGT013354 Peptidyl-prolyl cis-trans isomerase G 9360 reviewed
Q13627 BXGT013385 Dual specificity tyrosine-phosphorylation-regulated kinase 1A 1859 reviewed Kinase
Q14289 BXGT013459 Protein-tyrosine kinase 2-beta 2185 reviewed Kinase
Q14397 BXGT013467 Glucokinase regulatory protein 2646 reviewed
Q15031 BXGT013525 Probable leucine--tRNA ligase, mitochondrial 23395 reviewed Enzyme
Q15392 BXGT013566 Delta(24)-sterol reductase 1718 reviewed Enzyme
Q15843 BXGT013608 NEDD8 4738 reviewed Nucleic acid binding
Q16773 BXGT013667 Kynurenine--oxoglutarate transaminase 1 883 reviewed Enzyme
Q16790 BXGT013670 Carbonic anhydrase 9 768 reviewed
Q16850 BXGT013681 Lanosterol 14-alpha demethylase 1595 reviewed Enzyme
Q7L266 BXGT016993 Isoaspartyl peptidase/L-asparaginase 80150 reviewed Enzyme
Q8TDS5 BXGT018813 Oxoeicosanoid receptor 1 165140 reviewed G-protein coupled receptor
Q8TDV0 BXGT018815 Probable G-protein coupled receptor 151 134391 reviewed G-protein coupled receptor
Q96L34 BXGT019689 MAP/microtubule affinity-regulating kinase 4 57787 reviewed Kinase
Q99538 BXGT019931 Legumain 5641 reviewed Enzyme
Q99685 BXGT019948 Monoglyceride lipase 11343 reviewed Enzyme
Q9BZX2 BXGT020204 Uridine-cytidine kinase 2 7371 reviewed Kinase
Q9H0A0 BXGT020434 RNA cytidine acetyltransferase 55226 reviewed
Q9P2J5 BXGT021301 Leucine--tRNA ligase, cytoplasmic 51520 reviewed
Q9UBN7 BXGT021658 Histone deacetylase 6 10013 reviewed Epigenetic regulator
Q9UKV0 BXGT021750 Histone deacetylase 9 9734 reviewed Epigenetic regulator
Q9ULV1 BXGT021764 Frizzled-4 8322 reviewed G-protein coupled receptor
Q9Y4P1 BXGT022283 Cysteine protease ATG4B 23192 reviewed Enzyme
Q9Y6K1 BXGT022331 DNA (cytosine-5)-methyltransferase 3A 1788 reviewed
P00395 BXGT023596 Cytochrome c oxidase subunit 1 4512 reviewed Enzyme
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease