adisease

Showing entry for Vasculitis

General Disease Information
BXGD Id	BXGD002979
Disease Name	Vasculitis
Disease CUI Id	C0042384
MeSH Codes	C14
Disease Class Name	Cardiovascular Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0001626
Human Phenotype Ontology Term	Abnormality of the cardiovascular system
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O00602	BXGT003940	Ficolin-1	2219	reviewed	Signaling
O15123	BXGT004130	Angiopoietin-2	285	reviewed	Signaling
O15460	BXGT004172	Prolyl 4-hydroxylase subunit alpha-2	8974	reviewed
O15553	BXGT004181	Pyrin	4210	reviewed
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O75015	BXGT005095	Low affinity immunoglobulin gamma Fc region receptor III-B	2215	reviewed	Cell adhesion
O75369	BXGT005119	Filamin-B	2317	reviewed
O76054	BXGT005172	SEC14-like protein 2	23541	reviewed
O95267	BXGT005368	RAS guanyl-releasing protein 1	10125	reviewed	Enzyme modulator
P00450	BXGT005544	Ceruloplasmin	1356	reviewed	Enzyme
P00451	BXGT005545	Coagulation factor VIII	2157	reviewed	Enzyme
P00747	BXGT005639	Plasminogen	5340	reviewed	Enzyme
P00750	BXGT005642	Tissue-type plasminogen activator	5327	reviewed	Enzyme
P00813	BXGT005667	Adenosine deaminase	100	reviewed	Enzyme
P01009	BXGT005714	Alpha-1-antitrypsin	5265	reviewed	Enzyme modulator
P01011	BXGT005715	Alpha-1-antichymotrypsin	12	reviewed	Enzyme modulator
P01019	BXGT005717	Angiotensinogen	183	reviewed	Enzyme modulator
P01031	BXGT005720	Complement C5	727	reviewed	Enzyme modulator
P01133	BXGT005736	Pro-epidermal growth factor	1950	reviewed
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01138	BXGT005738	Beta-nerve growth factor	4803	reviewed	Signaling
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01589	BXGT005773	Interleukin-2 receptor subunit alpha	3559	reviewed	Receptor
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P01909	BXGT005815	HLA class II histocompatibility antigen, DQ alpha 1 chain	3117	reviewed	Immune response
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P01920	BXGT005817	HLA class II histocompatibility antigen, DQ beta 1 chain	3119	reviewed	Immune response
P02652	BXGT005910	Apolipoprotein A-II	336	reviewed	Transporter
P02724	BXGT005934	Glycophorin-A	2993	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02751	BXGT005943	Fibronectin	2335	reviewed	Signaling
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P04054	BXGT006136	Phospholipase A2	5319	reviewed	Enzyme
P04275	BXGT006180	von Willebrand factor	7450	reviewed	Enzyme modulator
P04440	BXGT006216	HLA class II histocompatibility antigen, DP beta 1 chain	3115	reviewed	Immune response
P05107	BXGT006316	Integrin beta-2	3689	reviewed	Receptor
P05109	BXGT006318	Protein S100-A8	6279	reviewed	Calcium-binding protein
P05155	BXGT006328	Plasma protease C1 inhibitor	710	reviewed	Enzyme modulator
P05156	BXGT006329	Complement factor I	3426	reviewed
P05161	BXGT006331	Ubiquitin-like protein ISG15	9636	reviewed	Nucleic acid binding
P05164	BXGT006333	Myeloperoxidase	4353	reviewed	Enzyme
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P05771	BXGT006384	Protein kinase C beta type	5579	reviewed	Kinase
P06702	BXGT006476	Protein S100-A9	6280	reviewed	Calcium-binding protein
P06733	BXGT006490	Alpha-enolase	2023	reviewed	Enzyme
P07237	BXGT006576	Protein disulfide-isomerase	5034	reviewed
P07900	BXGT006696	Heat shock protein HSP 90-alpha	3320	reviewed	Chaperone
P08246	BXGT006756	Neutrophil elastase	1991	reviewed	Enzyme
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08603	BXGT006798	Complement factor H	3075	reviewed
P08637	BXGT006802	Low affinity immunoglobulin gamma Fc region receptor III-A	2214	reviewed	Cell adhesion
P08842	BXGT006830	Steryl-sulfatase	412	reviewed	Enzyme
P09429	BXGT006889	High mobility group protein B1	3146	reviewed	Nucleic acid binding
P09466	BXGT006892	Glycodelin	5047	reviewed	Enzyme
P10323	BXGT007557	Acrosin	49	reviewed	Enzyme
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10747	BXGT007609	T-cell-specific surface glycoprotein CD28	940	reviewed
P11226	BXGT007675	Mannose-binding protein C	4153	reviewed	Receptor
P11712	BXGT007738	Cytochrome P450 2C9	1559	reviewed
P11912	BXGT007758	B-cell antigen receptor complex-associated protein alpha chain	973	reviewed	Receptor
P12318	BXGT007799	Low affinity immunoglobulin gamma Fc region receptor II-a	2212	reviewed	Cell adhesion
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P13501	BXGT007917	C-C motif chemokine 5	6352	reviewed	Signaling
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P14921	BXGT008068	Protein C-ets-1	2113	reviewed	Transcription factor
P15121	BXGT008083	Aldo-keto reductase family 1 member B1	231	reviewed	Enzyme
P15144	BXGT008087	Aminopeptidase N	290	reviewed	Enzyme
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P15813	BXGT008158	Antigen-presenting glycoprotein CD1d	912	reviewed
P16410	BXGT008224	Cytotoxic T-lymphocyte protein 4	1493	reviewed
P19320	BXGT008470	Vascular cell adhesion protein 1	7412	reviewed
P19438	BXGT008480	Tumor necrosis factor receptor superfamily member 1A	7132	reviewed
P19838	BXGT008526	Nuclear factor NF-kappa-B p105 subunit	4790	reviewed	Transcription factor
P20273	BXGT008557	B-cell receptor CD22	933	reviewed
P20810	BXGT008602	Calpastatin	831	reviewed
P21589	BXGT008669	5'-nucleotidase	4907	reviewed	Enzyme
P21730	BXGT008687	C5a anaphylatoxin chemotactic receptor 1	728	reviewed	G-protein coupled receptor
P22681	BXGT008795	E3 ubiquitin-protein ligase CBL	867	reviewed	Enzyme
P23975	BXGT008935	Sodium-dependent noradrenaline transporter	6530	reviewed	Transporter
P24158	BXGT008951	Myeloblastin	5657	reviewed	Enzyme
P25942	BXGT009079	Tumor necrosis factor receptor superfamily member 5	958	reviewed
P27797	BXGT009206	Calreticulin	811	reviewed	Calcium-binding protein
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P28676	BXGT009284	Grancalcin	25801	reviewed
P28702	BXGT009287	Retinoic acid receptor RXR-beta	6257	reviewed	Nuclear receptor
P29460	BXGT009348	Interleukin-12 subunit beta	3593	reviewed	Signaling
P29474	BXGT009352	Nitric oxide synthase, endothelial	4846	reviewed
P29597	BXGT009367	Non-receptor tyrosine-protein kinase TYK2	7297	reviewed	Kinase
P29965	BXGT009388	CD40 ligand	959	reviewed	Signaling
P33261	BXGT009707	Cytochrome P450 2C19	1557	reviewed
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P35869	BXGT009877	Aryl hydrocarbon receptor	196	reviewed	Transcription factor
P37840	BXGT010015	Alpha-synuclein	6622	reviewed	Transporter
P41240	BXGT010242	Tyrosine-protein kinase CSK	1445	reviewed	Kinase
P41597	BXGT010268	C-C chemokine receptor type 2	729230	reviewed
P43405	BXGT010386	Tyrosine-protein kinase SYK	6850	reviewed	Kinase
P45983	BXGT010494	Mitogen-activated protein kinase 8	5599	reviewed	Kinase
P46108	BXGT010509	Adapter molecule crk	1398	reviewed
P48023	BXGT010604	Tumor necrosis factor ligand superfamily member 6	356	reviewed	Signaling
P48357	BXGT010627	Leptin receptor	3953	reviewed	Signaling
P51451	BXGT010848	Tyrosine-protein kinase Blk	640	reviewed	Kinase
P51580	BXGT010864	Thiopurine S-methyltransferase	7172	reviewed
P51681	BXGT010878	C-C chemokine receptor type 5	1234	reviewed	G-protein coupled receptor
P54762	BXGT011076	Ephrin type-B receptor 1	2047	reviewed	Kinase
P60033	BXGT011286	CD81 antigen	975	reviewed
P60568	BXGT011315	Interleukin-2	3558	reviewed
P63104	BXGT011499	14-3-3 protein zeta/delta	7534	reviewed	Chaperone
P80511	BXGT011914	Protein S100-A12	6283	reviewed	Calcium-binding protein
P81172	BXGT011935	Hepcidin	57817	reviewed
P99999	BXGT012235	Cytochrome c	54205	reviewed
Q00653	BXGT012541	Nuclear factor NF-kappa-B p100 subunit	4791	reviewed	Transcription factor
Q01453	BXGT012588	Peripheral myelin protein 22	5376	reviewed	Cellular structure
Q05655	BXGT012832	Protein kinase C delta type	5580	reviewed	Kinase
Q07021	BXGT012915	Complement component 1 Q subcomponent-binding protein, mitochondrial	708	reviewed
Q09428	BXGT013036	ATP-binding cassette sub-family C member 8	6833	reviewed	Transporter
Q13155	BXGT013320	Aminoacyl tRNA synthase complex-interacting multifunctional protein 2	7965	reviewed
Q13938	BXGT013405	Calcyphosin	828	reviewed
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q14393	BXGT013466	Growth arrest-specific protein 6	2621	reviewed	Extracellular structure
Q15116	BXGT013539	Programmed cell death protein 1	5133	reviewed
Q15599	BXGT013583	Na(+)/H(+) exchange regulatory cofactor NHE-RF2	9351	reviewed
Q15858	BXGT013610	Sodium channel protein type 9 subunit alpha	6335	reviewed	Ion channel
Q16539	BXGT013634	Mitogen-activated protein kinase 14	1432	reviewed	Kinase
Q16637	BXGT013646	Survival motor neuron protein	6607	reviewed	Epigenetic regulator
Q5VWK5	BXGT015891	Interleukin-23 receptor	149233	reviewed	Signaling
Q5Y7D3	BXGT015912	HLA class II histocompatibility antigen DQ beta chain	3119	unreviewed
Q6EIG7	BXGT016267	C-type lectin domain family 6 member A	93978	reviewed	Receptor
Q86V24	BXGT017615	Adiponectin receptor protein 2	79602	reviewed	Receptor
Q86WV6	BXGT017626	Stimulator of interferon genes protein	340061	reviewed
Q8IV61	BXGT018340	Ras guanyl-releasing protein 3	25780	reviewed	Enzyme modulator
Q96AZ6	BXGT019621	Interferon-stimulated gene 20 kDa protein	3669	reviewed
Q96EN8	BXGT019649	Molybdenum cofactor sulfurase	55034	reviewed
Q96F46	BXGT019656	Interleukin-17 receptor A	23765	reviewed
Q96J66	BXGT019680	ATP-binding cassette sub-family C member 11	85320	reviewed	Transporter
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q96RJ3	BXGT019729	Tumor necrosis factor receptor superfamily member 13C	115650	reviewed
Q99836	BXGT019970	Myeloid differentiation primary response protein MyD88	4615	reviewed	Enzyme modulator
Q9BQE3	BXGT020109	Tubulin alpha-1C chain	84790	reviewed	Cellular structure
Q9H015	BXGT020432	Solute carrier family 22 member 4	6583	reviewed	Transporter
Q9HD26	BXGT020540	Golgi-associated PDZ and coiled-coil motif-containing protein	57120	reviewed
Q9NP99	BXGT021148	Triggering receptor expressed on myeloid cells 1	54210	reviewed
Q9NR96	BXGT021181	Toll-like receptor 9	54106	reviewed
Q9NYK1	BXGT021258	Toll-like receptor 7	51284	reviewed
Q9NZ08	BXGT021266	Endoplasmic reticulum aminopeptidase 1	51752	reviewed	Enzyme
Q9NZQ7	BXGT021281	Programmed cell death 1 ligand 1	29126	reviewed	Receptor
Q9UI33	BXGT021712	Sodium channel protein type 11 subunit alpha	11280	reviewed	Ion channel
Q9UM07	BXGT021771	Protein-arginine deiminase type-4	23569	reviewed
Q9Y2R2	BXGT022243	Tyrosine-protein phosphatase non-receptor type 22	26191	reviewed
Q9Y3Z3	BXGT022268	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1	25939	reviewed
Q9Y5Y9	BXGT022309	Sodium channel protein type 10 subunit alpha	6336	reviewed	Ion channel
P20036	BXGT022764	HLA class II histocompatibility antigen, DP alpha 1 chain	3113	reviewed	Immune response
Q9UM82	BXGT023181	Spermatogenesis-associated protein 2	9825	reviewed
P31994	BXGT023298	Low affinity immunoglobulin gamma Fc region receptor II-b	2213	reviewed	Cell adhesion
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
Q96QC4	BXGT023878	MHC class I polypeptide-related sequence A	100507436	unreviewed
Q96A54	BXGT024681	Adiponectin receptor protein 1	51094	reviewed	Receptor
P11836	BXGT025994	B-lymphocyte antigen CD20	931	reviewed	Receptor

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}