Showing entry for ATP-dependent RNA helicase DDX42


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT017630
Protein NameATP-dependent RNA helicase DDX42
Uniport IdQ86XP3
GeneDDX42
Gene Id11325
DomainDEAD; Helicase_C
Pfam PF00270   PF00271  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
2. Genetic Information Processing 2.1 Transcription hsa03040 Spliceosome
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0000398 mRNA splicing, via spliceosome
Biological Process GO:0008104 protein localization
Biological Process GO:0042981 regulation of apoptotic process
molecular function GO:0005524 ATP binding
molecular function GO:0003723 RNA binding
molecular function GO:0003724 RNA helicase activity
cellular component GO:0015030 Cajal body
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0016020 membrane
cellular component GO:0016607 nuclear speck
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-72163 mRNA Splicing - Major Pathway
R-HSA-72165 mRNA Splicing - Minor Pathway
R-HSA-72172 mRNA Splicing
R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA
R-HSA-8953854 Metabolism of RNA
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006625 BXGD000401 Cachexia Pathological Conditions, Signs and Symptoms
C0014057 BXGD000880 Japanese Encephalitis Infections; Nervous System Diseases
C0025149 BXGD001826 Medulloblastoma Neoplasms
C0278510 BXGD006526 Childhood Medulloblastoma Neoplasms
C0278876 BXGD006607 Adult Medulloblastoma Neoplasms
C1305855 BXGD012348 Body mass index
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0042376 Picropodophyllotoxin 414.13
BXGC0047692 Gefitinib 446.15
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein