Showing entry for Breast adenocarcinoma


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD011172
Disease NameBreast adenocarcinoma
Disease CUI IdC0858252
MeSH Codes C04   C17  
Disease Class NameNeoplasms; Skin and Connective Tissue Diseases
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7   DOID:14566  
Disease Ontology Class Namedisease of anatomical entity; disease of cellular proliferation
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O00264 BXGT003904 Membrane-associated progesterone receptor component 1 10857 reviewed Signaling
O15119 BXGT004128 T-box transcription factor TBX3 6926 reviewed Transcription factor
O15197 BXGT004136 Ephrin type-B receptor 6 2051 reviewed Kinase
O15530 BXGT004177 3-phosphoinositide-dependent protein kinase 1 5170 reviewed Kinase
O43283 BXGT004583 Mitogen-activated protein kinase kinase kinase 13 9175 reviewed Kinase
O75874 BXGT005157 Isocitrate dehydrogenase [NADP] cytoplasmic 3417 reviewed
O94759 BXGT005327 Transient receptor potential cation channel subfamily M member 2 7226 reviewed Ion channel
O96017 BXGT005415 Serine/threonine-protein kinase Chk2 11200 reviewed Kinase
P00374 BXGT005520 Dihydrofolate reductase 1719 reviewed Enzyme
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P01111 BXGT005731 GTPase NRas 4893 reviewed Enzyme modulator
P01112 BXGT005732 GTPase HRas 3265 reviewed Enzyme modulator
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01236 BXGT005744 Prolactin 5617 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P04155 BXGT006155 Trefoil factor 1 7031 reviewed Signaling
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04792 BXGT006264 Heat shock protein beta-1 3315 reviewed
P04798 BXGT006265 Cytochrome P450 1A1 1543 reviewed Enzyme
P05106 BXGT006315 Integrin beta-3 3690 reviewed Receptor
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P07203 BXGT006566 Glutathione peroxidase 1 2876 reviewed Enzyme
P07225 BXGT006572 Vitamin K-dependent protein S 5627 reviewed
P07288 BXGT006591 Prostate-specific antigen 354 reviewed Enzyme
P07858 BXGT006689 Cathepsin B 1508 reviewed Enzyme
P07900 BXGT006696 Heat shock protein HSP 90-alpha 3320 reviewed Chaperone
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08473 BXGT006773 Neprilysin 4311 reviewed Enzyme
P08620 BXGT006800 Fibroblast growth factor 4 2249 reviewed Signaling
P08758 BXGT006821 Annexin A5 308 reviewed
P09382 BXGT006882 Galectin-1 3956 reviewed Signaling
P09466 BXGT006892 Glycodelin 5047 reviewed Enzyme
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P11166 BXGT007661 Solute carrier family 2, facilitated glucose transporter member 1 6513 reviewed Transporter
P11362 BXGT007693 Fibroblast growth factor receptor 1 2260 reviewed Kinase
P11387 BXGT007696 DNA topoisomerase 1 7150 reviewed Enzyme
P11413 BXGT007701 Glucose-6-phosphate 1-dehydrogenase 2539 reviewed Enzyme
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P11511 BXGT007717 Aromatase 1588 reviewed Enzyme
P12004 BXGT007766 Proliferating cell nuclear antigen 5111 reviewed Nucleic acid binding
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P15121 BXGT008083 Aldo-keto reductase family 1 member B1 231 reviewed Enzyme
P15559 BXGT008139 NAD(P)H dehydrogenase [quinone] 1 1728 reviewed
P15941 BXGT008176 Mucin-1 4582 reviewed
P16671 BXGT008255 Platelet glycoprotein 4 948 reviewed Receptor
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 2321 reviewed Kinase
P18146 BXGT008384 Early growth response protein 1 1958 reviewed Nucleic acid binding
P19883 BXGT008528 Follistatin 10468 reviewed Enzyme modulator
P21291 BXGT008635 Cysteine and glycine-rich protein 1 1465 reviewed Cellular structure
P21860 BXGT008698 Receptor tyrosine-protein kinase erbB-3 2065 reviewed Kinase
P25942 BXGT009079 Tumor necrosis factor receptor superfamily member 5 958 reviewed
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29317 BXGT009331 Ephrin type-A receptor 2 1969 reviewed Kinase
P29320 BXGT009332 Ephrin type-A receptor 3 2042 reviewed Kinase
P29350 BXGT009335 Tyrosine-protein phosphatase non-receptor type 6 5777 reviewed
P30046 BXGT009396 D-dopachrome decarboxylase 1652 reviewed Enzyme
P30838 BXGT009471 Aldehyde dehydrogenase, dimeric NADP-preferring 218 reviewed
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P31751 BXGT009576 RAC-beta serine/threonine-protein kinase 208 reviewed Kinase
P35219 BXGT009797 Carbonic anhydrase-related protein 767 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35372 BXGT009823 Mu-type opioid receptor 4988 reviewed G-protein coupled receptor
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P37173 BXGT009970 TGF-beta receptor type-2 7048 reviewed Kinase
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P38398 BXGT010037 Breast cancer type 1 susceptibility protein 672 reviewed Enzyme
P38936 BXGT010074 Cyclin-dependent kinase inhibitor 1 1026 reviewed
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P45985 BXGT010496 Dual specificity mitogen-activated protein kinase kinase 4 6416 reviewed Kinase
P46108 BXGT010509 Adapter molecule crk 1398 reviewed
P46527 BXGT010525 Cyclin-dependent kinase inhibitor 1B 1027 reviewed
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P48506 BXGT010635 Glutamate--cysteine ligase catalytic subunit 2729 reviewed Enzyme
P49023 BXGT010672 Paxillin 5829 reviewed Cellular structure
P49908 BXGT010760 Selenoprotein P 6414 reviewed Extracellular structure
P50281 BXGT010788 Matrix metalloproteinase-14 4323 reviewed Enzyme
P50479 BXGT010804 PDZ and LIM domain protein 4 8572 reviewed Cellular structure
P50591 BXGT010814 Tumor necrosis factor ligand superfamily member 10 8743 reviewed Signaling
P52789 BXGT010954 Hexokinase-2 3099 reviewed Kinase
P55211 BXGT011111 Caspase-9 842 reviewed Enzyme
P55786 BXGT011125 Puromycin-sensitive aminopeptidase 9520 reviewed Enzyme
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P60568 BXGT011315 Interleukin-2 3558 reviewed
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P98170 BXGT012231 E3 ubiquitin-protein ligase XIAP 331 reviewed Enzyme modulator
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q04721 BXGT012777 Neurogenic locus notch homolog protein 2 4853 reviewed
Q06187 BXGT012860 Tyrosine-protein kinase BTK 695 reviewed Kinase
Q07157 BXGT012920 Tight junction protein ZO-1 7082 reviewed Cell-cell junction
Q07812 BXGT012940 Apoptosis regulator BAX 581 reviewed Signaling
Q07820 BXGT012942 Induced myeloid leukemia cell differentiation protein Mcl-1 4170 reviewed Signaling
Q09472 BXGT013038 Histone acetyltransferase p300 2033 reviewed
Q13155 BXGT013320 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 7965 reviewed
Q14457 BXGT013472 Beclin-1 8678 reviewed Enzyme modulator
Q14680 BXGT013499 Maternal embryonic leucine zipper kinase 9833 reviewed Kinase
Q14790 BXGT013505 Caspase-8 841 reviewed Enzyme
Q15233 BXGT013552 Non-POU domain-containing octamer-binding protein 4841 reviewed Nucleic acid binding
Q15303 BXGT013557 Receptor tyrosine-protein kinase erbB-4 2066 reviewed Kinase
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16539 BXGT013634 Mitogen-activated protein kinase 14 1432 reviewed Kinase
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16678 BXGT013656 Cytochrome P450 1B1 1545 reviewed Enzyme
Q16739 BXGT013663 Ceramide glucosyltransferase 7357 reviewed Enzyme
Q6ZVK8 BXGT016640 8-oxo-dGDP phosphatase NUDT18 79873 reviewed
Q86TM3 BXGT017607 Probable ATP-dependent RNA helicase DDX53 168400 reviewed
Q86U86 BXGT017611 Protein polybromo-1 55193 reviewed Epigenetic regulator
Q86YC2 BXGT017633 Partner and localizer of BRCA2 79728 reviewed
Q8N371 BXGT018504 Bifunctional peptidase and arginyl-hydroxylase JMJD5 79831 reviewed
Q8NFD5 BXGT018560 AT-rich interactive domain-containing protein 1B 57492 reviewed
Q92993 BXGT019403 Histone acetyltransferase KAT5 10524 reviewed
Q9H0R8 BXGT020441 Gamma-aminobutyric acid receptor-associated protein-like 1 23710 reviewed Cellular structure
Q9H1D0 BXGT020445 Transient receptor potential cation channel subfamily V member 6 55503 reviewed Ion channel
Q9H3M7 BXGT020462 Thioredoxin-interacting protein 10628 reviewed
Q9NR12 BXGT021174 PDZ and LIM domain protein 7 9260 reviewed Cellular structure
Q9UK32 BXGT021736 Ribosomal protein S6 kinase alpha-6 27330 reviewed Kinase
Q9UNQ0 BXGT021792 ATP-binding cassette sub-family G member 2 9429 reviewed Transporter
Q9Y251 BXGT022215 Heparanase 10855 reviewed Enzyme
Q9Y617 BXGT022314 Phosphoserine aminotransferase 29968 reviewed
Q13330 BXGT023103 Metastasis-associated protein MTA1 9112 reviewed Nucleic acid binding
O14793 BXGT023280 Growth/differentiation factor 8 2660 reviewed Signaling
Q9GZQ8 BXGT023414 Microtubule-associated proteins 1A/1B light chain 3B 81631 reviewed Cellular structure
P16104 BXGT024571 Histone H2AX 3014 reviewed Nucleic acid binding
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease