Showing entry for Rhodopsin kinase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT018984
Protein NameRhodopsin kinase
Uniport IdQ8WTQ7
GeneGRK7
Gene Id131890
DomainPkinase; RGS
Pfam PF00069   PF00615  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.1 Immune system hsa04062 Chemokine signaling pathway
4. Cellular Processes 4.1 Transport and catabolism hsa04144 Endocytosis
5. Organismal Systems 5.7 Sensory system hsa04744 Phototransduction
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0046777 protein autophosphorylation
Biological Process GO:0022400 regulation of rhodopsin mediated signaling pathway
Biological Process GO:0007165 signal transduction
Biological Process GO:0007601 visual perception
molecular function GO:0005524 ATP binding
molecular function GO:0004703 G protein-coupled receptor kinase activity
molecular function GO:0050254 rhodopsin kinase activity
cellular component GO:0097381 photoreceptor disc membrane
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-2187338 Visual phototransduction
R-HSA-2514856 The phototransduction cascade
R-HSA-2514859 Inactivation, recovery and regulation of the phototransduction cascade
R-HSA-372790 Signaling by GPCR
R-HSA-388396 GPCR downstream signalling
R-HSA-418594 G alpha (i) signalling events
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0025202 BXGD001832 melanoma Neoplasms
C0035334 BXGD002539 Retinitis Pigmentosa Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0278883 BXGD006614 Metastatic melanoma Neoplasms
C0339535 BXGD007263 Night blindness, congenital stationary Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C1306122 BXGD012355 Oguchi disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C1849394 BXGD015048 Enhanced S-Cone Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Nervous System Diseases
C1857743 BXGD015745 LEBER CONGENITAL AMAUROSIS 12 (disorder) Eye Diseases
C3551052 BXGD019144 Night blindness, stationary
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0012352 Chelerythrine 348.12
BXGC0044857 Sp-600125 220.06
BXGC0045254 Sb-202190 331.11
BXGC0047692 Gefitinib 446.15
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein