Showing entry for Sp-600125


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0044857
Compound NameSp-600125
Structure
FormulaC14H8N2O
InchiKeyKRIUNPBAQZGFQA-UHFFFAOYSA-N
SMILESOc1c2ccccc2c2c3c1cccc3N=N2
InchiInChI=1S/C14H8N2O/c17-14-9-5-2-1-4-8(9)13-12-10(14)6-3-7-11(12)15-16-13/h1-7,17H
IUPAC
Molecular Weight220.06
Pubchem Id
Chembl IdCHEMBL1725279
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB 50024294
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT014526 Serine/threonine-protein kinase ULK3 reviewed Ulk3 - - 680 -
reviewed BXGT011014 Mitogen-activated protein kinase 10 reviewed Kinase MAPK10 - - 22 -
reviewed BXGT013558 Ribosomal protein S6 kinase alpha-2 reviewed Kinase RPS6KA2 - - 2200 -
reviewed BXGT021810 Aurora kinase C reviewed Kinase AURKC - - 5300 -
reviewed BXGT008151 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform reviewed Kinase PHKG2 - - 480 -
reviewed BXGT010494 Mitogen-activated protein kinase 8 reviewed Kinase MAPK8 - - 100 -
reviewed BXGT019702 Calcium/calmodulin-dependent protein kinase type 1G reviewed Kinase CAMK1G - - 4200 -
reviewed BXGT009332 Ephrin type-A receptor 3 reviewed Kinase EPHA3 - - 4000 -
reviewed BXGT022233 Serine/threonine-protein kinase 38-like reviewed Kinase STK38L - - 2300 -
reviewed BXGT018333 Calcium/calmodulin-dependent protein kinase type 1D reviewed Kinase CAMK1D - - 1400 -
reviewed BXGT004117 Aurora kinase A reviewed Kinase AURKA - - 980 -
reviewed BXGT021720 Death-associated protein kinase 2 reviewed Kinase DAPK2 - - 610 -
reviewed BXGT019734 Calcium/calmodulin-dependent protein kinase kinase 2 reviewed Kinase CAMKK2 - - 7500 -
reviewed BXGT021671 Serine/threonine-protein kinase 17A reviewed Kinase STK17A - - 2100 -
reviewed BXGT021209 BMP-2-inducible protein kinase reviewed Kinase BMP2K - - 25 -
reviewed BXGT003921 Serine/threonine-protein kinase PLK4 reviewed Kinase PLK4 - - 770 -
reviewed BXGT020511 Dual specificity protein kinase CLK4 reviewed CLK4 - - 260 -
reviewed BXGT013307 Serine/threonine-protein kinase 4 reviewed Kinase STK4 - - 2200 -
reviewed BXGT009002 Cyclin-dependent kinase 2 reviewed Kinase CDK2 - - 3200 -
reviewed BXGT010725 Casein kinase I isoform epsilon reviewed CSNK1E - - 3100 -
reviewed BXGT004584 Death-associated protein kinase 3 reviewed Kinase DAPK3 - - 410 -
reviewed BXGT009744 Dual specificity protein kinase TTK reviewed Kinase TTK - - 98 -
reviewed BXGT020811 Serine/threonine-protein kinase 3 reviewed Stk3 - - 220 -
reviewed BXGT020536 Casein kinase I isoform gamma-1 reviewed Kinase CSNK1G1 - - 3700 -
reviewed BXGT020521 MAP kinase-interacting serine/threonine-protein kinase 2 reviewed Kinase MKNK2 - - 1000 -
reviewed BXGT016990 Serine/threonine-protein kinase MARK2 reviewed Kinase MARK2 - - 1800 -
reviewed BXGT010495 Mitogen-activated protein kinase 9 reviewed Kinase MAPK9 - - 84 -
reviewed BXGT014130 AP2-associated protein kinase 1 reviewed Kinase AAK1 - - 35 -
reviewed BXGT010735 Dual specificity protein kinase CLK2 reviewed Kinase CLK2 - - 300 -
reviewed BXGT013437 Calcium/calmodulin-dependent protein kinase type 1 reviewed Kinase CAMK1 - - 4100 -
reviewed BXGT012535 Cyclin-dependent kinase 16 reviewed Kinase CDK16 - - 180 -
reviewed BXGT020452 STE20-like serine/threonine-protein kinase reviewed Kinase SLK - - 2300 -
reviewed BXGT005147 Serine/threonine-protein kinase 16 reviewed Kinase STK16 - - 510 -
reviewed BXGT004118 Cyclin-G-associated kinase reviewed Kinase GAK - - 38 -
reviewed BXGT021741 TRAF2 and NCK-interacting protein kinase reviewed Kinase TNIK - - 480 -
reviewed BXGT021296 Serine/threonine-protein kinase pim-2 reviewed Kinase PIM2 - - 460 -
reviewed BXGT011013 Mitogen-activated protein kinase 12 reviewed Kinase MAPK12 - - 2400 -
reviewed BXGT005137 Ribosomal protein S6 kinase alpha-5 reviewed Kinase RPS6KA5 - - 1700 -
reviewed BXGT009744 Dual specificity protein kinase TTK reviewed Kinase TTK - 2500 - -
reviewed BXGT010494 Mitogen-activated protein kinase 8 reviewed Kinase MAPK8 - 40 - -
reviewed BXGT010495 Mitogen-activated protein kinase 9 reviewed Kinase MAPK9 - 40 - -
reviewed BXGT011014 Mitogen-activated protein kinase 10 reviewed Kinase MAPK10 - 90 - -
CHEMBL CHEMBL1725279
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
Q9NQU5 BXGT021169 Serine/threonine-protein kinase PAK 6 reviewed - PAK6 Kd - - -
Q99640 BXGT019944 Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase reviewed Kinase PKMYT1 Kd - - -
O15530 BXGT004177 3-phosphoinositide-dependent protein kinase 1 reviewed Kinase PDPK1 Residual Activity '=' 19 %
Q9P1W9 BXGT021296 Serine/threonine-protein kinase pim-2 reviewed Kinase PIM2 Residual Activity '=' 21 %
P29466 BXGT009349 Caspase-1 reviewed Enzyme CASP1 Potency '=' 3981 nM
P06213 BXGT006425 Insulin receptor reviewed Kinase INSR Residual Activity '=' 26 %
P29322 BXGT009333 Ephrin type-A receptor 8 reviewed Kinase EPHA8 Residual Activity '=' 76 %
P42685 BXGT010332 Tyrosine-protein kinase FRK reviewed Kinase FRK Kd - - -
P09769 BXGT006917 Tyrosine-protein kinase Fgr reviewed Kinase FGR Kd - - -
P54762 BXGT011076 Ephrin type-B receptor 1 reviewed Kinase EPHB1 Kd - - -
Q16816 BXGT013673 Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform reviewed Kinase PHKG1 Kd - - -
P21802 BXGT008691 Fibroblast growth factor receptor 2 reviewed Kinase FGFR2 Kd - - -
P36888 BXGT009938 Receptor-type tyrosine-protein kinase FLT3 reviewed Kinase FLT3 Kd - - -
Q13976 BXGT013409 cGMP-dependent protein kinase 1 reviewed Kinase PRKG1 Ki '>' 1995 nM
P31751 BXGT009576 RAC-beta serine/threonine-protein kinase reviewed Kinase AKT2 Ki '>' 7943 nM
P48730 BXGT010656 Casein kinase I isoform delta reviewed Kinase CSNK1D Activity '=' 15 %
O75116 BXGT005100 Rho-associated protein kinase 2 reviewed Kinase ROCK2 Ki '=' 3162 nM
P12931 BXGT007859 Proto-oncogene tyrosine-protein kinase Src reviewed Kinase SRC Ki '>' 1995 nM
O15264 BXGT004144 Mitogen-activated protein kinase 13 reviewed Kinase MAPK13 Ki '>' 7943 nM
P48730 BXGT010656 Casein kinase I isoform delta reviewed Kinase CSNK1D Ki '=' 31 nM
P51955 BXGT010908 Serine/threonine-protein kinase Nek2 reviewed Kinase NEK2 Residual Activity '=' 81 %
P51813 BXGT010894 Cytoplasmic tyrosine-protein kinase BMX reviewed Kinase BMX Kd - - -
P06493 BXGT006445 Cyclin-dependent kinase 1 reviewed Kinase CDK1 Ki '=' 1000 nM
P28482 BXGT009263 Mitogen-activated protein kinase 1 reviewed Kinase MAPK1 Potency '=' 10000 nM
P11362 BXGT007693 Fibroblast growth factor receptor 1 reviewed Kinase FGFR1 Ki '=' 251 nM
Q16644 BXGT013647 MAP kinase-activated protein kinase 3 reviewed Kinase MAPKAPK3 Ki '>' 10000 nM
O75914 BXGT005165 Serine/threonine-protein kinase PAK 3 reviewed Kinase PAK3 Residual Activity '=' 85 %
Q9UGI9 BXGT021682 5'-AMP-activated protein kinase subunit gamma-3 reviewed Enzyme modulator PRKAG3 Residual Activity '=' 28 %
Q13131 BXGT013314 5'-AMP-activated protein kinase catalytic subunit alpha-1 reviewed Kinase PRKAA1 Residual Activity '=' 28 %
Q9Y478 BXGT022271 5'-AMP-activated protein kinase subunit beta-1 reviewed Kinase PRKAB1 Residual Activity '=' 28 %
Q9UGJ0 BXGT021683 5'-AMP-activated protein kinase subunit gamma-2 reviewed Enzyme modulator PRKAG2 Residual Activity '=' 28 %
P54619 BXGT011060 5'-AMP-activated protein kinase subunit gamma-1 reviewed Kinase PRKAG1 Residual Activity '=' 28 %
O43741 BXGT004620 5'-AMP-activated protein kinase subunit beta-2 reviewed Enzyme modulator PRKAB2 Residual Activity '=' 28 %
P54646 BXGT011062 5'-AMP-activated protein kinase catalytic subunit alpha-2 reviewed Kinase PRKAA2 Residual Activity '=' 28 %
P15735 BXGT008151 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform reviewed Kinase PHKG2 Residual Activity '=' 15 %
Q14680 BXGT013499 Maternal embryonic leucine zipper kinase reviewed Kinase MELK Ki '=' 398 nM
Q9NR20 BXGT021176 Dual specificity tyrosine-phosphorylation-regulated kinase 4 reviewed Kinase DYRK4 Ki '>' 7943 nM
O00311 BXGT003908 Cell division cycle 7-related protein kinase reviewed Kinase CDC7 Ki '=' 1000 nM
P08069 BXGT006723 Insulin-like growth factor 1 receptor reviewed Kinase IGF1R Residual Activity '=' 91 %
P23443 BXGT008866 Ribosomal protein S6 kinase beta-1 reviewed Kinase RPS6KB1 Residual Activity '=' 55 %
P07949 BXGT006703 Proto-oncogene tyrosine-protein kinase receptor Ret reviewed Kinase RET Residual Activity '=' 43 %
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase reviewed Kinase AKT1 Ki '>' 7943 nM
Q13627 BXGT013385 Dual specificity tyrosine-phosphorylation-regulated kinase 1A reviewed Kinase DYRK1A Ki '=' 125 nM
P08069 BXGT006723 Insulin-like growth factor 1 receptor reviewed Kinase IGF1R Residual Activity '=' 92 %
Q14012 BXGT013437 Calcium/calmodulin-dependent protein kinase type 1 reviewed Kinase CAMK1 Residual Activity '=' 32 %
P28482 BXGT009263 Mitogen-activated protein kinase 1 reviewed Kinase MAPK1 Residual Activity '=' 55 %
P43250 BXGT010372 G protein-coupled receptor kinase 6 reviewed Kinase GRK6 Residual Activity '=' 87 %
P51812 BXGT010893 Ribosomal protein S6 kinase alpha-3 reviewed Kinase RPS6KA3 Ki '=' 398 nM
Q86V86 BXGT017617 Serine/threonine-protein kinase pim-3 reviewed - PIM3 Ki '=' 199 nM
P42685 BXGT010332 Tyrosine-protein kinase FRK reviewed Kinase FRK Ki '=' 63 nM
O54968 BXGT004738 Nuclear factor erythroid 2-related factor 2 reviewed - Nfe2l2 Activity - - -
Q13882 BXGT013399 Protein-tyrosine kinase 6 reviewed Kinase PTK6 Kd - - -
Q96NX5 BXGT019702 Calcium/calmodulin-dependent protein kinase type 1G reviewed Kinase CAMK1G Kd '=' 4200 nM
P23458 BXGT008868 Tyrosine-protein kinase JAK1 reviewed Kinase JAK1 Kd - - -
O14976 BXGT004118 Cyclin-G-associated kinase reviewed Kinase GAK Kd '=' 38 nM
Q13131 BXGT013314 5'-AMP-activated protein kinase catalytic subunit alpha-1 reviewed Kinase PRKAA1 Kd - - -
P06241 BXGT006429 Tyrosine-protein kinase Fyn reviewed Kinase FYN Kd - - -
P45984 BXGT010495 Mitogen-activated protein kinase 9 reviewed Kinase MAPK9 Ki '=' 50 nM
Q5VT25 BXGT015887 Serine/threonine-protein kinase MRCK alpha reviewed Kinase CDC42BPA Residual Activity '=' 115 %
Q06187 BXGT012860 Tyrosine-protein kinase BTK reviewed Kinase BTK Ki '>' 1258 nM
O15264 BXGT004144 Mitogen-activated protein kinase 13 reviewed Kinase MAPK13 Residual Activity '=' 96 %
P42685 BXGT010332 Tyrosine-protein kinase FRK reviewed Kinase FRK Residual Activity '=' 58 %
Q16644 BXGT013647 MAP kinase-activated protein kinase 3 reviewed Kinase MAPKAPK3 Residual Activity '=' 100 %
Q8IWQ3 BXGT018355 Serine/threonine-protein kinase BRSK2 reviewed Kinase BRSK2 Residual Activity '=' 9 %
O75116 BXGT005100 Rho-associated protein kinase 2 reviewed Kinase ROCK2 Activity '=' 92 %
P51812 BXGT010893 Ribosomal protein S6 kinase alpha-3 reviewed Kinase RPS6KA3 Activity '=' 70 %
P31751 BXGT009576 RAC-beta serine/threonine-protein kinase reviewed Kinase AKT2 Activity '=' 92 %
Q9BUB5 BXGT020133 MAP kinase-interacting serine/threonine-protein kinase 1 reviewed Kinase MKNK1 Activity '=' 67 %
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 29092 nM
Q9Y3S1 BXGT022266 Serine/threonine-protein kinase WNK2 reviewed Kinase WNK2 Residual Activity '=' 77 %
P48730 BXGT010656 Casein kinase I isoform delta reviewed Kinase CSNK1D Residual Activity '=' 5 %
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 AC50 - - -
P43250 BXGT010372 G protein-coupled receptor kinase 6 reviewed Kinase GRK6 Residual Activity '=' 81 %
Q8N5S9 BXGT018520 Calcium/calmodulin-dependent protein kinase kinase 1 reviewed Kinase CAMKK1 Activity '=' 68 %
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase reviewed Kinase AKT1 Residual Activity '=' 110 %
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 6683 nM
Q13043 BXGT013307 Serine/threonine-protein kinase 4 reviewed Kinase STK4 Residual Activity '=' 52 %
O15146 BXGT004131 Muscle, skeletal receptor tyrosine-protein kinase reviewed Kinase MUSK Residual Activity '=' 60 %
Q16832 BXGT013678 Discoidin domain-containing receptor 2 reviewed Kinase DDR2 Residual Activity '=' 93 %
O14965 BXGT004117 Aurora kinase A reviewed Kinase AURKA Residual Activity '=' 2 %
O14733 BXGT004087 Dual specificity mitogen-activated protein kinase kinase 7 reviewed Kinase MAP2K7 Residual Activity '=' 58 %
Q86V86 BXGT017617 Serine/threonine-protein kinase pim-3 reviewed - PIM3 Residual Activity '=' 75 %
Q13188 BXGT013324 Serine/threonine-protein kinase 3 reviewed Kinase STK3 Residual Activity '=' 10 %
Q9BYP7 BXGT020188 Serine/threonine-protein kinase WNK3 reviewed Kinase WNK3 Residual Activity '=' 87 %
P06213 BXGT006425 Insulin receptor reviewed Kinase INSR Residual Activity '=' 47 %
O60285 BXGT004867 NUAK family SNF1-like kinase 1 reviewed Kinase NUAK1 Residual Activity '=' 17 %
Q9UL54 BXGT021755 Serine/threonine-protein kinase TAO2 reviewed Kinase TAOK2 Residual Activity '=' 101 %
Q99683 BXGT019947 Mitogen-activated protein kinase kinase kinase 5 reviewed Kinase MAP3K5 Residual Activity '=' 36 %
Q06418 BXGT012875 Tyrosine-protein kinase receptor TYRO3 reviewed Kinase TYRO3 Residual Activity '=' 97 %
P51617 BXGT010868 Interleukin-1 receptor-associated kinase 1 reviewed Kinase IRAK1 Residual Activity '=' 42 %
Q9BYT3 BXGT020189 Serine/threonine-protein kinase 33 reviewed Kinase STK33 Residual Activity '=' 16 %
Q9UK32 BXGT021736 Ribosomal protein S6 kinase alpha-6 reviewed Kinase RPS6KA6 Residual Activity '=' 43 %
O14965 BXGT004117 Aurora kinase A reviewed Kinase AURKA Residual Activity '=' 19 %
Q9UHD2 BXGT021697 Serine/threonine-protein kinase TBK1 reviewed Kinase TBK1 Residual Activity '=' 35 %
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 AC50 '=' 398 nM
Q16513 BXGT013632 Serine/threonine-protein kinase N2 reviewed Kinase PKN2 Ki '>' 7943 nM
Q9UM73 BXGT021773 ALK tyrosine kinase receptor reviewed Kinase ALK Inhibition '>' 50 %
Q8WTQ7 BXGT018984 Rhodopsin kinase reviewed Kinase GRK7 Residual Activity '=' 27 %
Q6PHR2 BXGT016467 Serine/threonine-protein kinase ULK3 reviewed Kinase ULK3 Residual Activity '=' 73 %
P78362 BXGT011839 SRSF protein kinase 2 reviewed Kinase SRPK2 Residual Activity '=' 97 %
Q9HC98 BXGT020528 Serine/threonine-protein kinase Nek6 reviewed Kinase NEK6 Residual Activity '=' 107 %
P51813 BXGT010894 Cytoplasmic tyrosine-protein kinase BMX reviewed Kinase BMX Residual Activity '=' 18 %
Q13976 BXGT013409 cGMP-dependent protein kinase 1 reviewed Kinase PRKG1 Residual Activity '=' 90 %
Q02763 BXGT012667 Angiopoietin-1 receptor reviewed Kinase TEK Residual Activity '=' 95 %
Q9UHD2 BXGT021697 Serine/threonine-protein kinase TBK1 reviewed Kinase TBK1 Residual Activity '=' 11 %
Q13555 BXGT013375 Calcium/calmodulin-dependent protein kinase type II subunit gamma reviewed Kinase CAMK2G Residual Activity '=' 37 %
P50613 BXGT010815 Cyclin-dependent kinase 7 reviewed Kinase CDK7 Residual Activity '=' 75 %
P51946 BXGT010907 Cyclin-H reviewed Enzyme modulator CCNH Residual Activity '=' 75 %
P04049 BXGT006133 RAF proto-oncogene serine/threonine-protein kinase reviewed Kinase RAF1 Residual Activity '=' 69 %
P51955 BXGT010908 Serine/threonine-protein kinase Nek2 reviewed Kinase NEK2 Activity '=' 78 %
Q9H2X6 BXGT020458 Homeodomain-interacting protein kinase 2 reviewed Kinase HIPK2 Activity '=' 35 %
P07332 BXGT006601 Tyrosine-protein kinase Fes/Fps reviewed Kinase FES Ki '=' 79 nM
P48729 BXGT010655 Casein kinase I isoform alpha reviewed Kinase CSNK1A1 Ki '=' 316 nM
Q8WTQ7 BXGT018984 Rhodopsin kinase reviewed Kinase GRK7 Residual Activity '=' 71 %
P07948 BXGT006702 Tyrosine-protein kinase Lyn reviewed Kinase LYN Residual Activity '=' 70 %
O43318 BXGT004586 Mitogen-activated protein kinase kinase kinase 7 reviewed Kinase MAP3K7 Residual Activity '=' 41 %
P54760 BXGT011075 Ephrin type-B receptor 4 reviewed Kinase EPHB4 Residual Activity '=' 89 %
P21709 BXGT008685 Ephrin type-A receptor 1 reviewed Kinase EPHA1 Residual Activity '=' 42 %
Q7KZI7 BXGT016990 Serine/threonine-protein kinase MARK2 reviewed Kinase MARK2 Residual Activity '=' 55 %
P53350 BXGT010984 Serine/threonine-protein kinase PLK1 reviewed Kinase PLK1 Residual Activity '=' 69 %
P45984 BXGT010495 Mitogen-activated protein kinase 9 reviewed Kinase MAPK9 IC50 '=' 40 nM
O43293 BXGT004584 Death-associated protein kinase 3 reviewed Kinase DAPK3 Kd '=' 410 nM
O94768 BXGT005331 Serine/threonine-protein kinase 17B reviewed Kinase STK17B Kd - - -
P00519 BXGT005570 Tyrosine-protein kinase ABL1 reviewed Kinase ABL1 Kd - - -
P45984 BXGT010495 Mitogen-activated protein kinase 9 reviewed Kinase MAPK9 Activity '=' 24 %
P06746 BXGT006496 DNA polymerase beta reviewed Enzyme POLB Potency '=' 31622 nM
P00352 BXGT005510 Retinal dehydrogenase 1 reviewed Enzyme ALDH1A1 Potency '=' 3162 nM
Q14680 BXGT013499 Maternal embryonic leucine zipper kinase reviewed Kinase MELK Residual Activity '=' 0 %
P06213 BXGT006425 Insulin receptor reviewed Kinase INSR Residual Activity '=' 70 %
Q86Z02 BXGT017638 Homeodomain-interacting protein kinase 1 reviewed Kinase HIPK1 Residual Activity '=' 62 %
P07332 BXGT006601 Tyrosine-protein kinase Fes/Fps reviewed Kinase FES Residual Activity '=' 34 %
Q16644 BXGT013647 MAP kinase-activated protein kinase 3 reviewed Kinase MAPKAPK3 Activity '=' 103 %
P11309 BXGT007685 Serine/threonine-protein kinase pim-1 reviewed Kinase PIM1 Activity '=' 39 %
Q96SB4 BXGT019740 SRSF protein kinase 1 reviewed Kinase SRPK1 Activity '=' 84 %
Q05513 BXGT012820 Protein kinase C zeta type reviewed Kinase PRKCZ Activity '=' 106 %
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 10000 nM
P55210 BXGT011110 Caspase-7 reviewed Enzyme CASP7 Potency '=' 3162 nM
P04629 BXGT006239 High affinity nerve growth factor receptor reviewed Kinase NTRK1 Ki '=' 1258 nM
P51451 BXGT010848 Tyrosine-protein kinase Blk reviewed Kinase BLK Ki '=' 199 nM
P49137 BXGT010680 MAP kinase-activated protein kinase 2 reviewed Kinase MAPKAPK2 Ki '>' 7943 nM
P17612 BXGT008322 cAMP-dependent protein kinase catalytic subunit alpha reviewed Kinase PRKACA Ki '>' 7943 nM
P51955 BXGT010908 Serine/threonine-protein kinase Nek2 reviewed Kinase NEK2 Ki '=' 6309 nM
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 3548 nM
Q9P1W9 BXGT021296 Serine/threonine-protein kinase pim-2 reviewed Kinase PIM2 Residual Activity '=' 58 %
P43405 BXGT010386 Tyrosine-protein kinase SYK reviewed Kinase SYK Ki '=' 63 nM
Q00535 BXGT012534 Cyclin-dependent-like kinase 5 reviewed Kinase CDK5 Ki '=' 1000 nM
Q96SB4 BXGT019740 SRSF protein kinase 1 reviewed Kinase SRPK1 Residual Activity '=' 98 %
P06239 BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK Residual Activity '=' 43 %
P51956 BXGT010909 Serine/threonine-protein kinase Nek3 reviewed Kinase NEK3 Residual Activity '=' 70 %
Q9H422 BXGT020469 Homeodomain-interacting protein kinase 3 reviewed Kinase HIPK3 Activity '=' 56 %
Q9HC98 BXGT020528 Serine/threonine-protein kinase Nek6 reviewed Kinase NEK6 Activity '=' 102 %
O14920 BXGT004110 Inhibitor of nuclear factor kappa-B kinase subunit beta reviewed Kinase IKBKB Activity '=' 49 %
Q9P286 BXGT021299 Serine/threonine-protein kinase PAK 5 reviewed Kinase PAK5 Activity '=' 82 %
P28482 BXGT009263 Mitogen-activated protein kinase 1 reviewed Kinase MAPK1 Activity '=' 86 %
P49761 BXGT010736 Dual specificity protein kinase CLK3 reviewed Kinase CLK3 Kd - - -
Q9NSY1 BXGT021209 BMP-2-inducible protein kinase reviewed Kinase BMP2K Kd '=' 25 nM
P15917 BXGT008169 Lethal factor reviewed - lef Potency '=' 15848 nM
P87108 BXGT012099 Mitochondrial import inner membrane translocase subunit TIM10 reviewed - TIM10 IC50 '>' 100000 nM
P51817 BXGT010895 cAMP-dependent protein kinase catalytic subunit PRKX reviewed Kinase PRKX Ki '>' 1584 nM
P00352 BXGT005510 Retinal dehydrogenase 1 reviewed Enzyme ALDH1A1 Potency '=' 12589 nM
O00444 BXGT003921 Serine/threonine-protein kinase PLK4 reviewed Kinase PLK4 Ki '=' 199 nM
Q5VT25 BXGT015887 Serine/threonine-protein kinase MRCK alpha reviewed Kinase CDC42BPA Ki '>' 10000 nM
P36888 BXGT009938 Receptor-type tyrosine-protein kinase FLT3 reviewed Kinase FLT3 Ki '=' 50 nM
P07948 BXGT006702 Tyrosine-protein kinase Lyn reviewed Kinase LYN Kd - - -
P54756 BXGT011074 Ephrin type-A receptor 5 reviewed Kinase EPHA5 Kd - - -
P07947 BXGT006701 Tyrosine-protein kinase Yes reviewed Kinase YES1 Kd - - -
P54756 BXGT011074 Ephrin type-A receptor 5 reviewed Kinase EPHA5 Residual Activity '=' 63 %
P48730 BXGT010656 Casein kinase I isoform delta reviewed Kinase CSNK1D Residual Activity '=' 1 %
O96013 BXGT005414 Serine/threonine-protein kinase PAK 4 reviewed Kinase PAK4 Residual Activity '=' 45 %
Q05397 BXGT012815 Focal adhesion kinase 1 reviewed Kinase PTK2 Residual Activity '=' 52 %
P05771 BXGT006384 Protein kinase C beta type reviewed Kinase PRKCB Residual Activity '=' 108 %
Q9UGI9 BXGT021682 5'-AMP-activated protein kinase subunit gamma-3 reviewed Enzyme modulator PRKAG3 Residual Activity '=' 69 %
Q13131 BXGT013314 5'-AMP-activated protein kinase catalytic subunit alpha-1 reviewed Kinase PRKAA1 Residual Activity '=' 69 %
Q9Y478 BXGT022271 5'-AMP-activated protein kinase subunit beta-1 reviewed Kinase PRKAB1 Residual Activity '=' 69 %
Q9UGJ0 BXGT021683 5'-AMP-activated protein kinase subunit gamma-2 reviewed Enzyme modulator PRKAG2 Residual Activity '=' 69 %
P54619 BXGT011060 5'-AMP-activated protein kinase subunit gamma-1 reviewed Kinase PRKAG1 Residual Activity '=' 69 %
O43741 BXGT004620 5'-AMP-activated protein kinase subunit beta-2 reviewed Enzyme modulator PRKAB2 Residual Activity '=' 69 %
P54646 BXGT011062 5'-AMP-activated protein kinase catalytic subunit alpha-2 reviewed Kinase PRKAA2 Residual Activity '=' 69 %
P41240 BXGT010242 Tyrosine-protein kinase CSK reviewed Kinase CSK Activity '=' 65 %
P39748 BXGT010134 Flap endonuclease 1 reviewed Enzyme FEN1 Potency - 19952 nM
P53779 BXGT011014 Mitogen-activated protein kinase 10 reviewed Kinase MAPK10 Activity '=' 47 %
P35456 BXGT009834 Urokinase plasminogen activator surface receptor reviewed - Plaur Potency - 32885 nM
P20918 BXGT008615 Plasminogen reviewed - Plg Potency - 32885 nM
P06869 BXGT006517 Urokinase-type plasminogen activator reviewed - Plau Potency - 32885 nM
O00141 BXGT003882 Serine/threonine-protein kinase Sgk1 reviewed Kinase SGK1 Activity '=' 28 %
P11309 BXGT007685 Serine/threonine-protein kinase pim-1 reviewed Kinase PIM1 Kd - - -
Q8IWQ3 BXGT018355 Serine/threonine-protein kinase BRSK2 reviewed Kinase BRSK2 Activity '=' 44 %
Q96PF2 BXGT019708 Testis-specific serine/threonine-protein kinase 2 reviewed Kinase TSSK2 Ki '>' 1584 nM
Q9P1W9 BXGT021296 Serine/threonine-protein kinase pim-2 reviewed Kinase PIM2 Inhibition - - -
P49760 BXGT010735 Dual specificity protein kinase CLK2 reviewed Kinase CLK2 Inhibition - - -
Q13188 BXGT013324 Serine/threonine-protein kinase 3 reviewed Kinase STK3 Inhibition - - -
P42684 BXGT010331 Tyrosine-protein kinase ABL2 reviewed Kinase ABL2 Residual Activity '=' 72 %
P29323 BXGT009334 Ephrin type-B receptor 2 reviewed Kinase EPHB2 Residual Activity '=' 101 %
P29317 BXGT009331 Ephrin type-A receptor 2 reviewed Kinase EPHA2 Residual Activity '=' 60 %
Q15303 BXGT013557 Receptor tyrosine-protein kinase erbB-4 reviewed Kinase ERBB4 Residual Activity '=' 104 %
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 reviewed Kinase KDR Residual Activity '=' 3 %
Q04759 BXGT012781 Protein kinase C theta type reviewed Kinase PRKCQ Residual Activity '=' 90 %
O75116 BXGT005100 Rho-associated protein kinase 2 reviewed Kinase ROCK2 Residual Activity '=' 74 %
Q06187 BXGT012860 Tyrosine-protein kinase BTK reviewed Kinase BTK Kd - - -
P06240 BXGT006428 Proto-oncogene tyrosine-protein kinase LCK reviewed - Lck Activity '=' 68 %
P49841 BXGT010750 Glycogen synthase kinase-3 beta reviewed Kinase GSK3B Activity '=' 81 %
Q9BXA7 BXGT020164 Testis-specific serine/threonine-protein kinase 1 reviewed Kinase TSSK1B Residual Activity '=' 49 %
Q16644 BXGT013647 MAP kinase-activated protein kinase 3 reviewed Kinase MAPKAPK3 Residual Activity '=' 103 %
Q13554 BXGT013374 Calcium/calmodulin-dependent protein kinase type II subunit beta reviewed Kinase CAMK2B Kd - - -
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 Potency '=' 25118 nM
P49840 BXGT010749 Glycogen synthase kinase-3 alpha reviewed Kinase GSK3A Ki '=' 1258 nM
P53350 BXGT010984 Serine/threonine-protein kinase PLK1 reviewed Kinase PLK1 Activity '=' 80 %
P23443 BXGT008866 Ribosomal protein S6 kinase beta-1 reviewed Kinase RPS6KB1 Activity '=' 85 %
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 16360 nM
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A reviewed - KMT2A Potency '=' 28183 nM
O00255 BXGT003903 Menin reviewed - MEN1 Potency '=' 28183 nM
O15264 BXGT004144 Mitogen-activated protein kinase 13 reviewed Kinase MAPK13 Activity '=' 82 %
B2RXH2 BXGT002006 Lysine-specific demethylase 4E reviewed - KDM4E Potency '=' 12589 nM
Q9Y243 BXGT022214 RAC-gamma serine/threonine-protein kinase reviewed Kinase AKT3 Ki '>' 10000 nM
P02791 BXGT005965 Ferritin light chain reviewed - FTL Potency '=' 17782 nM
P11473 BXGT007709 Vitamin D3 receptor reviewed Nuclear receptor VDR Potency - 50118 nM
Q9UBE8 BXGT021652 Serine/threonine-protein kinase NLK reviewed Kinase NLK Residual Activity '=' 78 %
Q9P0L2 BXGT021289 Serine/threonine-protein kinase MARK1 reviewed Kinase MARK1 Residual Activity '=' 38 %
Q86Y07 BXGT017631 Serine/threonine-protein kinase VRK2 reviewed Kinase VRK2 Residual Activity '=' 36 %
P57059 BXGT011210 Serine/threonine-protein kinase SIK1 reviewed - SIK1 Residual Activity '=' 96 %
P14635 BXGT008031 G2/mitotic-specific cyclin-B1 reviewed Enzyme modulator CCNB1 Residual Activity '=' 52 %
P06493 BXGT006445 Cyclin-dependent kinase 1 reviewed Kinase CDK1 Residual Activity '=' 52 %
P49137 BXGT010680 MAP kinase-activated protein kinase 2 reviewed Kinase MAPKAPK2 Residual Activity '=' 69 %
P08922 BXGT006843 Proto-oncogene tyrosine-protein kinase ROS reviewed Kinase ROS1 Residual Activity '=' 93 %
P00352 BXGT005510 Retinal dehydrogenase 1 reviewed Enzyme ALDH1A1 Potency '=' 25118 nM
P53779 BXGT011014 Mitogen-activated protein kinase 10 reviewed Kinase MAPK10 Kd '=' 22 nM
Q13237 BXGT013331 cGMP-dependent protein kinase 2 reviewed Kinase PRKG2 Ki '>' 1584 nM
P53779 BXGT011014 Mitogen-activated protein kinase 10 reviewed Kinase MAPK10 IC50 '=' 190 nM
Q9Y6E0 BXGT022327 Serine/threonine-protein kinase 24 reviewed Kinase STK24 Residual Activity '=' 57 %
Q96GD4 BXGT019667 Aurora kinase B reviewed Kinase AURKB Residual Activity '=' 1 %
P49840 BXGT010749 Glycogen synthase kinase-3 alpha reviewed Kinase GSK3A Residual Activity '=' 40 %
O15118 BXGT004127 NPC intracellular cholesterol transporter 1 reviewed Transporter NPC1 Potency '=' 10322 nM
P43405 BXGT010386 Tyrosine-protein kinase SYK reviewed Kinase SYK Residual Activity '=' 77 %
P10721 BXGT007605 Mast/stem cell growth factor receptor Kit reviewed Kinase KIT Residual Activity '=' 91 %
Q8TDX7 BXGT018817 Serine/threonine-protein kinase Nek7 reviewed Kinase NEK7 Activity '=' 112 %
P40225 BXGT010168 Thrombopoietin reviewed - THPO Potency '=' 5011 nM
O89049 BXGT005293 Thioredoxin reductase 1, cytoplasmic reviewed - Txnrd1 Potency - 26679 nM
Q9P286 BXGT021299 Serine/threonine-protein kinase PAK 5 reviewed Kinase PAK5 Kd - - -
Q9UF33 BXGT021676 Ephrin type-A receptor 6 reviewed Kinase EPHA6 Kd - - -
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 reviewed Kinase ERBB2 Kd - - -
P36888 BXGT009938 Receptor-type tyrosine-protein kinase FLT3 reviewed Kinase FLT3 Residual Activity '=' 1 %
P53667 BXGT011008 LIM domain kinase 1 reviewed Kinase LIMK1 Kd - - -
P06241 BXGT006429 Tyrosine-protein kinase Fyn reviewed Kinase FYN Residual Activity '=' 60 %
Q13526 BXGT013369 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 reviewed - PIN1 Potency - 26854 nM
Q86V86 BXGT017617 Serine/threonine-protein kinase pim-3 reviewed - PIM3 Activity '=' 17 %
P29322 BXGT009333 Ephrin type-A receptor 8 reviewed Kinase EPHA8 Residual Activity '=' 92 %
Q9UBT6 BXGT021664 DNA polymerase kappa reviewed - POLK Potency - 10000 nM
Q06187 BXGT012860 Tyrosine-protein kinase BTK reviewed Kinase BTK Residual Activity '=' 57 %
P06239 BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK Residual Activity '=' 69 %
P00519 BXGT005570 Tyrosine-protein kinase ABL1 reviewed Kinase ABL1 Residual Activity '=' 56 %
P52333 BXGT010928 Tyrosine-protein kinase JAK3 reviewed Kinase JAK3 Residual Activity '=' 57 %
P49137 BXGT010680 MAP kinase-activated protein kinase 2 reviewed Kinase MAPKAPK2 Activity '=' 102 %
P19784 BXGT008513 Casein kinase II subunit alpha' reviewed Kinase CSNK2A2 Activity '=' 57 %
P68400 BXGT011599 Casein kinase II subunit alpha reviewed Kinase CSNK2A1 Activity '=' 57 %
P67870 BXGT011566 Casein kinase II subunit beta reviewed Kinase CSNK2B Activity '=' 57 %
Q99714 BXGT019954 3-hydroxyacyl-CoA dehydrogenase type-2 reviewed Enzyme HSD17B10 Potency '=' 39810 nM
P17252 BXGT008294 Protein kinase C alpha type reviewed Kinase PRKCA Activity '=' 68 %
Q92630 BXGT019360 Dual specificity tyrosine-phosphorylation-regulated kinase 2 reviewed Kinase DYRK2 Activity '=' 19 %
O96017 BXGT005415 Serine/threonine-protein kinase Chk2 reviewed Kinase CHEK2 Activity '=' 44 %
Q13131 BXGT013314 5'-AMP-activated protein kinase catalytic subunit alpha-1 reviewed Kinase PRKAA1 Ki '>' 1584 nM
Q9P1W9 BXGT021296 Serine/threonine-protein kinase pim-2 reviewed Kinase PIM2 Ki '=' 316 nM
P53779 BXGT011014 Mitogen-activated protein kinase 10 reviewed Kinase MAPK10 IC50 '=' 90 nM
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 AC50 - - -
P16473 BXGT008234 Thyrotropin receptor reviewed G-protein coupled receptor TSHR Potency '=' 39810 nM
P51812 BXGT010893 Ribosomal protein S6 kinase alpha-3 reviewed Kinase RPS6KA3 Kd - - -
Q9Y4K4 BXGT022282 Mitogen-activated protein kinase kinase kinase kinase 5 reviewed Kinase MAP4K5 Kd - - -
P45984 BXGT010495 Mitogen-activated protein kinase 9 reviewed Kinase MAPK9 Kd '=' 84 nM
P06239 BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK Kd - - -
Q00535 BXGT012534 Cyclin-dependent-like kinase 5 reviewed Kinase CDK5 Kd - - -
Q9UKE5 BXGT021741 TRAF2 and NCK-interacting protein kinase reviewed Kinase TNIK Kd '=' 480 nM
P54760 BXGT011075 Ephrin type-B receptor 4 reviewed Kinase EPHB4 Kd - - -
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 21136 nM
P15289 BXGT008102 Arylsulfatase A reviewed Enzyme ARSA Potency - 601 nM
Q9NQU5 BXGT021169 Serine/threonine-protein kinase PAK 6 reviewed - PAK6 Activity '=' 72 %
O00418 BXGT003918 Eukaryotic elongation factor 2 kinase reviewed Kinase EEF2K Activity '=' 118 %
Q9P1W9 BXGT021296 Serine/threonine-protein kinase pim-2 reviewed Kinase PIM2 Activity '=' 58 %
Q15375 BXGT013562 Ephrin type-A receptor 7 reviewed Kinase EPHA7 Kd - - -
Q8TD19 BXGT018804 Serine/threonine-protein kinase Nek9 reviewed Kinase NEK9 Kd - - -
Q99683 BXGT019947 Mitogen-activated protein kinase kinase kinase 5 reviewed Kinase MAP3K5 Kd - - -
Q9HBH9 BXGT020521 MAP kinase-interacting serine/threonine-protein kinase 2 reviewed Kinase MKNK2 Kd '=' 1000 nM
Q13153 BXGT013319 Serine/threonine-protein kinase PAK 1 reviewed Kinase PAK1 Kd - - -
Q00534 BXGT012533 Cyclin-dependent kinase 6 reviewed Kinase CDK6 Residual Activity '=' 76 %
P30281 BXGT009416 G1/S-specific cyclin-D3 reviewed Enzyme modulator CCND3 Residual Activity '=' 76 %
P41240 BXGT010242 Tyrosine-protein kinase CSK reviewed Kinase CSK Residual Activity '=' 105 %
Q9UBE8 BXGT021652 Serine/threonine-protein kinase NLK reviewed Kinase NLK Residual Activity '=' 71 %
P42681 BXGT010330 Tyrosine-protein kinase TXK reviewed Kinase TXK Residual Activity '=' 58 %
Q8TDC3 BXGT018808 Serine/threonine-protein kinase BRSK1 reviewed Kinase BRSK1 Ki '=' 794 nM
P54764 BXGT011078 Ephrin type-A receptor 4 reviewed Kinase EPHA4 Residual Activity '=' 106 %
Q9Y6M4 BXGT022335 Casein kinase I isoform gamma-3 reviewed Kinase CSNK1G3 Residual Activity '=' 31 %
Q8N5S9 BXGT018520 Calcium/calmodulin-dependent protein kinase kinase 1 reviewed Kinase CAMKK1 Kd - - -
P16591 BXGT008246 Tyrosine-protein kinase Fer reviewed Kinase FER Kd - - -
Q02750 BXGT012662 Dual specificity mitogen-activated protein kinase kinase 1 reviewed Kinase MAP2K1 Residual Activity '=' 75 %
P43405 BXGT010386 Tyrosine-protein kinase SYK reviewed Kinase SYK Kd - - -
P22455 BXGT008772 Fibroblast growth factor receptor 4 reviewed Kinase FGFR4 Residual Activity '=' 110 %
P53778 BXGT011013 Mitogen-activated protein kinase 12 reviewed Kinase MAPK12 Kd '=' 2400 nM
Q9Y2H1 BXGT022233 Serine/threonine-protein kinase 38-like reviewed Kinase STK38L Kd '=' 2300 nM
P09619 BXGT006911 Platelet-derived growth factor receptor beta reviewed Kinase PDGFRB Kd - - -
O14965 BXGT004117 Aurora kinase A reviewed Kinase AURKA Kd '=' 980 nM
Q96RR4 BXGT019734 Calcium/calmodulin-dependent protein kinase kinase 2 reviewed Kinase CAMKK2 Kd '=' 7500 nM
Q14012 BXGT013437 Calcium/calmodulin-dependent protein kinase type 1 reviewed Kinase CAMK1 Kd '=' 4100 nM
Q07912 BXGT012947 Activated CDC42 kinase 1 reviewed Kinase TNK2 Kd - - -
Q9UQM7 BXGT021814 Calcium/calmodulin-dependent protein kinase type II subunit alpha reviewed Kinase CAMK2A Kd - - -
Q9Y6R4 BXGT022340 Mitogen-activated protein kinase kinase kinase 4 reviewed Kinase MAP3K4 Kd - - -
Q9H2G2 BXGT020452 STE20-like serine/threonine-protein kinase reviewed Kinase SLK Kd '=' 2300 nM
Q02763 BXGT012667 Angiopoietin-1 receptor reviewed Kinase TEK Kd - - -
P10721 BXGT007605 Mast/stem cell growth factor receptor Kit reviewed Kinase KIT Kd - - -
P22607 BXGT008784 Fibroblast growth factor receptor 3 reviewed Kinase FGFR3 Kd - - -
Q13043 BXGT013307 Serine/threonine-protein kinase 4 reviewed Kinase STK4 Kd '=' 2200 nM
Q16620 BXGT013645 BDNF/NT-3 growth factors receptor reviewed Kinase NTRK2 Residual Activity '=' 32 %
Q92630 BXGT019360 Dual specificity tyrosine-phosphorylation-regulated kinase 2 reviewed Kinase DYRK2 Residual Activity '=' -5 %
Q13131 BXGT013314 5'-AMP-activated protein kinase catalytic subunit alpha-1 reviewed Kinase PRKAA1 Residual Activity '=' 24 %
Q9Y478 BXGT022271 5'-AMP-activated protein kinase subunit beta-1 reviewed Kinase PRKAB1 Residual Activity '=' 24 %
P54619 BXGT011060 5'-AMP-activated protein kinase subunit gamma-1 reviewed Kinase PRKAG1 Residual Activity '=' 24 %
Q16620 BXGT013645 BDNF/NT-3 growth factors receptor reviewed Kinase NTRK2 Residual Activity '=' 5 %
P49759 BXGT010734 Dual specificity protein kinase CLK1 reviewed Kinase CLK1 Kd - - -
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A reviewed - KMT2A Potency '=' 10000 nM
O00255 BXGT003903 Menin reviewed - MEN1 Potency '=' 10000 nM
Q9BYT3 BXGT020189 Serine/threonine-protein kinase 33 reviewed Kinase STK33 Residual Activity '=' 61 %
P45983 BXGT010494 Mitogen-activated protein kinase 8 reviewed Kinase MAPK8 IC50 '=' 40 nM
P33981 BXGT009744 Dual specificity protein kinase TTK reviewed Kinase TTK Kd '=' 98 nM
O15530 BXGT004177 3-phosphoinositide-dependent protein kinase 1 reviewed Kinase PDPK1 Ki '=' 630 nM
P49674 BXGT010725 Casein kinase I isoform epsilon reviewed - CSNK1E Kd '=' 3100 nM
P29320 BXGT009332 Ephrin type-A receptor 3 reviewed Kinase EPHA3 Kd '=' 4000 nM
Q9HBH9 BXGT020521 MAP kinase-interacting serine/threonine-protein kinase 2 reviewed Kinase MKNK2 Activity '=' 59 %
P29317 BXGT009331 Ephrin type-A receptor 2 reviewed Kinase EPHA2 Kd - - -
Q9UIK4 BXGT021720 Death-associated protein kinase 2 reviewed Kinase DAPK2 Kd '=' 610 nM
O43781 BXGT004625 Dual specificity tyrosine-phosphorylation-regulated kinase 3 reviewed Kinase DYRK3 Activity '=' 30 %
Q14680 BXGT013499 Maternal embryonic leucine zipper kinase reviewed Kinase MELK Activity '=' 15 %
Q96PF2 BXGT019708 Testis-specific serine/threonine-protein kinase 2 reviewed Kinase TSSK2 Residual Activity '=' 86 %
Q13554 BXGT013374 Calcium/calmodulin-dependent protein kinase type II subunit beta reviewed Kinase CAMK2B Residual Activity '=' 47 %
Q9H2X6 BXGT020458 Homeodomain-interacting protein kinase 2 reviewed Kinase HIPK2 Residual Activity '=' 15 %
P49760 BXGT010735 Dual specificity protein kinase CLK2 reviewed Kinase CLK2 Residual Activity '=' 36 %
Q96BR1 BXGT019627 Serine/threonine-protein kinase Sgk3 reviewed - SGK3 Residual Activity '=' 85 %
Q06187 BXGT012860 Tyrosine-protein kinase BTK reviewed Kinase BTK Residual Activity '=' 88 %
Q08881 BXGT013012 Tyrosine-protein kinase ITK/TSK reviewed Kinase ITK Residual Activity '=' 67 %
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 5956 nM
O00141 BXGT003882 Serine/threonine-protein kinase Sgk1 reviewed Kinase SGK1 Residual Activity '=' 60 %
O15530 BXGT004177 3-phosphoinositide-dependent protein kinase 1 reviewed Kinase PDPK1 Residual Activity '=' 72 %
O96013 BXGT005414 Serine/threonine-protein kinase PAK 4 reviewed Kinase PAK4 Ki '>' 5011 nM
Q14012 BXGT013437 Calcium/calmodulin-dependent protein kinase type 1 reviewed Kinase CAMK1 Activity '=' 73 %
Q8IW41 BXGT018352 MAP kinase-activated protein kinase 5 reviewed Kinase MAPKAPK5 Activity '=' 58 %
Q13188 BXGT013324 Serine/threonine-protein kinase 3 reviewed Kinase STK3 Residual Activity '=' 16 %
P49761 BXGT010736 Dual specificity protein kinase CLK3 reviewed Kinase CLK3 Residual Activity '=' 72 %
P53667 BXGT011008 LIM domain kinase 1 reviewed Kinase LIMK1 Residual Activity '=' 64 %
O60674 BXGT004892 Tyrosine-protein kinase JAK2 reviewed Kinase JAK2 Residual Activity '=' 58 %
O95819 BXGT005398 Mitogen-activated protein kinase kinase kinase kinase 4 reviewed Kinase MAP4K4 Ki '=' 316 nM
Q15139 BXGT013546 Serine/threonine-protein kinase D1 reviewed Kinase PRKD1 Residual Activity '=' -1 %
P45983 BXGT010494 Mitogen-activated protein kinase 8 reviewed Kinase MAPK8 IC50 '=' 110 nM
Q9BXA7 BXGT020164 Testis-specific serine/threonine-protein kinase 1 reviewed Kinase TSSK1B Ki '>' 1584 nM
Q9UIK4 BXGT021720 Death-associated protein kinase 2 reviewed Kinase DAPK2 Residual Activity '=' 43 %
Q8N568 BXGT018516 Serine/threonine-protein kinase DCLK2 reviewed Kinase DCLK2 Residual Activity '=' 116 %
P17252 BXGT008294 Protein kinase C alpha type reviewed Kinase PRKCA Residual Activity '=' 98 %
Q02156 BXGT012639 Protein kinase C epsilon type reviewed Kinase PRKCE Residual Activity '=' 84 %
Q9HCP0 BXGT020536 Casein kinase I isoform gamma-1 reviewed Kinase CSNK1G1 Residual Activity '=' 48 %
P07333 BXGT006602 Macrophage colony-stimulating factor 1 receptor reviewed Kinase CSF1R Residual Activity '=' 36 %
Q15078 BXGT013534 Cyclin-dependent kinase 5 activator 1 reviewed Enzyme modulator CDK5R1 Residual Activity '=' 0 %
Q00535 BXGT012534 Cyclin-dependent-like kinase 5 reviewed Kinase CDK5 Residual Activity '=' 0 %
Q15349 BXGT013558 Ribosomal protein S6 kinase alpha-2 reviewed Kinase RPS6KA2 Residual Activity '=' 22 %
P19784 BXGT008513 Casein kinase II subunit alpha' reviewed Kinase CSNK2A2 Residual Activity '=' 18 %
Q86UE8 BXGT017612 Serine/threonine-protein kinase tousled-like 2 reviewed Kinase TLK2 Residual Activity '=' 38 %
P12931 BXGT007859 Proto-oncogene tyrosine-protein kinase Src reviewed Kinase SRC Kd - - -
Q8NG66 BXGT018566 Serine/threonine-protein kinase Nek11 reviewed Kinase NEK11 Residual Activity '=' 50 %
Q9BZL6 BXGT020199 Serine/threonine-protein kinase D2 reviewed Kinase PRKD2 Residual Activity '=' 92 %
O75914 BXGT005165 Serine/threonine-protein kinase PAK 3 reviewed Kinase PAK3 Residual Activity '=' 96 %
Q9Y243 BXGT022214 RAC-gamma serine/threonine-protein kinase reviewed Kinase AKT3 Residual Activity '=' 66 %
P51812 BXGT010893 Ribosomal protein S6 kinase alpha-3 reviewed Kinase RPS6KA3 Residual Activity '=' 54 %
Q9H4B4 BXGT020474 Serine/threonine-protein kinase PLK3 reviewed Kinase PLK3 Residual Activity '=' 82 %
O94804 BXGT005334 Serine/threonine-protein kinase 10 reviewed Kinase STK10 Residual Activity '=' 62 %
Q9HBH9 BXGT020521 MAP kinase-interacting serine/threonine-protein kinase 2 reviewed Kinase MKNK2 Residual Activity '=' 43 %
O14733 BXGT004087 Dual specificity mitogen-activated protein kinase kinase 7 reviewed Kinase MAP2K7 Residual Activity '=' 6 %
O43293 BXGT004584 Death-associated protein kinase 3 reviewed Kinase DAPK3 Residual Activity '=' 87 %
P87108 BXGT012099 Mitochondrial import inner membrane translocase subunit TIM10 reviewed - TIM10 IC50 '=' 20200 nM
Q9NWZ3 BXGT021239 Interleukin-1 receptor-associated kinase 4 reviewed Kinase IRAK4 Ki '=' 158 nM
P35916 BXGT009881 Vascular endothelial growth factor receptor 3 reviewed Kinase FLT4 Ki '=' 15 nM
P00352 BXGT005510 Retinal dehydrogenase 1 reviewed Enzyme ALDH1A1 Potency '=' 19952 nM
P53778 BXGT011013 Mitogen-activated protein kinase 12 reviewed Kinase MAPK12 Activity '=' 86 %
P17252 BXGT008294 Protein kinase C alpha type reviewed Kinase PRKCA Kd - - -
Q2M2I8 BXGT014130 AP2-associated protein kinase 1 reviewed Kinase AAK1 Kd '=' 35 nM
Q9HAZ1 BXGT020511 Dual specificity protein kinase CLK4 reviewed - CLK4 Kd '=' 260 nM
Q9HCP0 BXGT020536 Casein kinase I isoform gamma-1 reviewed Kinase CSNK1G1 Kd '=' 3700 nM
Q9H1R3 BXGT020446 Myosin light chain kinase 2, skeletal/cardiac muscle reviewed Kinase MYLK2 Kd - - -
P07948 BXGT006702 Tyrosine-protein kinase Lyn reviewed Kinase LYN Ki '=' 1000 nM
P0A6C1 BXGT007045 Endonuclease 4 reviewed - nfo Potency '=' 3981 nM
Q8IWQ3 BXGT018355 Serine/threonine-protein kinase BRSK2 reviewed Kinase BRSK2 Residual Activity '=' 64 %
P43403 BXGT010385 Tyrosine-protein kinase ZAP-70 reviewed Kinase ZAP70 Residual Activity '=' 94 %
Q9UL54 BXGT021755 Serine/threonine-protein kinase TAO2 reviewed Kinase TAOK2 Residual Activity '=' 69 %
O00418 BXGT003918 Eukaryotic elongation factor 2 kinase reviewed Kinase EEF2K Residual Activity '=' 112 %
P51955 BXGT010908 Serine/threonine-protein kinase Nek2 reviewed Kinase NEK2 Kd - - -
Q16513 BXGT013632 Serine/threonine-protein kinase N2 reviewed Kinase PKN2 Activity '=' 70 %
P33981 BXGT009744 Dual specificity protein kinase TTK reviewed Kinase TTK IC50 '=' 98 nM
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A reviewed - KMT2A Potency '=' 31622 nM
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase reviewed - APEX1 Potency - 28183 nM
P19784 BXGT008513 Casein kinase II subunit alpha' reviewed Kinase CSNK2A2 Residual Activity '=' 19 %
P68400 BXGT011599 Casein kinase II subunit alpha reviewed Kinase CSNK2A1 Residual Activity '=' 19 %
P67870 BXGT011566 Casein kinase II subunit beta reviewed Kinase CSNK2B Residual Activity '=' 19 %
P42679 BXGT010328 Megakaryocyte-associated tyrosine-protein kinase reviewed Kinase MATK Ki '=' 501 nM
Q4Q090 BXGT014858 2,3-bisphosphoglycerate-independent phosphoglycerate mutase unreviewed - PGAM Potency - 21331 nM
P11362 BXGT007693 Fibroblast growth factor receptor 1 reviewed Kinase FGFR1 Residual Activity '=' 39 %
P19784 BXGT008513 Casein kinase II subunit alpha' reviewed Kinase CSNK2A2 Residual Activity '=' 60 %
P68400 BXGT011599 Casein kinase II subunit alpha reviewed Kinase CSNK2A1 Residual Activity '=' 60 %
P67870 BXGT011566 Casein kinase II subunit beta reviewed Kinase CSNK2B Residual Activity '=' 60 %
P16591 BXGT008246 Tyrosine-protein kinase Fer reviewed Kinase FER Residual Activity '=' 75 %
Q86Z02 BXGT017638 Homeodomain-interacting protein kinase 1 reviewed Kinase HIPK1 Residual Activity '=' 93 %
Q15375 BXGT013562 Ephrin type-A receptor 7 reviewed Kinase EPHA7 Residual Activity '=' 80 %
P54762 BXGT011076 Ephrin type-B receptor 1 reviewed Kinase EPHB1 Residual Activity '=' 29 %
Q13882 BXGT013399 Protein-tyrosine kinase 6 reviewed Kinase PTK6 Residual Activity '=' 95 %
O43318 BXGT004586 Mitogen-activated protein kinase kinase kinase 7 reviewed Kinase MAP3K7 Residual Activity '=' 19 %
Q05655 BXGT012832 Protein kinase C delta type reviewed Kinase PRKCD Residual Activity '=' 71 %
P49761 BXGT010736 Dual specificity protein kinase CLK3 reviewed Kinase CLK3 Residual Activity '=' 34 %
O95149 BXGT005350 Snurportin-1 reviewed - SNUPN Potency - 35481 nM
Q14974 BXGT013516 Importin subunit beta-1 reviewed Transporter KPNB1 Potency - 35481 nM
P62826 BXGT011463 GTP-binding nuclear protein Ran reviewed Enzyme modulator RAN Potency - 35481 nM
Q9UNA4 BXGT021785 DNA polymerase iota reviewed - POLI Potency - 28183 nM
Q8TDC3 BXGT018808 Serine/threonine-protein kinase BRSK1 reviewed Kinase BRSK1 Residual Activity '=' 29 %
P41240 BXGT010242 Tyrosine-protein kinase CSK reviewed Kinase CSK Residual Activity '=' 93 %
P06241 BXGT006429 Tyrosine-protein kinase Fyn reviewed Kinase FYN Ki '>' 794 nM
Q05513 BXGT012820 Protein kinase C zeta type reviewed Kinase PRKCZ Ki '>' 7943 nM
P06213 BXGT006425 Insulin receptor reviewed Kinase INSR Ki '=' 501 nM
O43293 BXGT004584 Death-associated protein kinase 3 reviewed Kinase DAPK3 Ki '=' 398 nM
P32897 BXGT009676 Mitochondrial import inner membrane translocase subunit TIM23 reviewed - TIM23 IC50 '=' 6310 nM
Q9HBY8 BXGT020524 Serine/threonine-protein kinase Sgk2 reviewed Kinase SGK2 Ki '=' 251 nM
Q9BZL6 BXGT020199 Serine/threonine-protein kinase D2 reviewed Kinase PRKD2 Ki '=' 158 nM
Q8NE63 BXGT018551 Homeodomain-interacting protein kinase 4 reviewed Kinase HIPK4 Ki '=' 1995 nM
P68400 BXGT011599 Casein kinase II subunit alpha reviewed Kinase CSNK2A1 Ki '=' 501 nM
Q96KQ7 BXGT019687 Histone-lysine N-methyltransferase EHMT2 reviewed Epigenetic regulator EHMT2 Potency - 562 nM
P49841 BXGT010750 Glycogen synthase kinase-3 beta reviewed Kinase GSK3B Residual Activity '=' 74 %
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha reviewed Transcription factor HIF1A Potency '=' 15848 nM
O89049 BXGT005293 Thioredoxin reductase 1, cytoplasmic reviewed - Txnrd1 Potency - 89125 nM
P24941 BXGT009002 Cyclin-dependent kinase 2 reviewed Kinase CDK2 Kd '=' 3200 nM
Q05397 BXGT012815 Focal adhesion kinase 1 reviewed Kinase PTK2 Kd - - -
O96013 BXGT005414 Serine/threonine-protein kinase PAK 4 reviewed Kinase PAK4 Kd - - -
Q8NG66 BXGT018566 Serine/threonine-protein kinase Nek11 reviewed Kinase NEK11 Residual Activity '=' 47 %
P49841 BXGT010750 Glycogen synthase kinase-3 beta reviewed Kinase GSK3B Residual Activity '=' 58 %
P17612 BXGT008322 cAMP-dependent protein kinase catalytic subunit alpha reviewed Kinase PRKACA Residual Activity '=' 73 %
P04629 BXGT006239 High affinity nerve growth factor receptor reviewed Kinase NTRK1 Residual Activity '=' 10 %
P08581 BXGT006794 Hepatocyte growth factor receptor reviewed Kinase MET Ki '=' 501 nM
O96013 BXGT005414 Serine/threonine-protein kinase PAK 4 reviewed Kinase PAK4 Activity '=' 60 %
Q05655 BXGT012832 Protein kinase C delta type reviewed Kinase PRKCD Ki '>' 7943 nM
P07949 BXGT006703 Proto-oncogene tyrosine-protein kinase receptor Ret reviewed Kinase RET Ki '=' 63 nM
Q05513 BXGT012820 Protein kinase C zeta type reviewed Kinase PRKCZ Residual Activity '=' 106 %
Q15303 BXGT013557 Receptor tyrosine-protein kinase erbB-4 reviewed Kinase ERBB4 Residual Activity '=' 97 %
Q15746 BXGT013591 Myosin light chain kinase, smooth muscle reviewed Kinase MYLK Residual Activity '=' 29 %
P12931 BXGT007859 Proto-oncogene tyrosine-protein kinase Src reviewed Kinase SRC Residual Activity '=' 89 %
Q9NR56 BXGT021179 Muscleblind-like protein 1 reviewed Nucleic acid binding MBNL1 Potency - 10000 nM
O00141 BXGT003882 Serine/threonine-protein kinase Sgk1 reviewed Kinase SGK1 Residual Activity '=' 24 %
P10721 BXGT007605 Mast/stem cell growth factor receptor Kit reviewed Kinase KIT Residual Activity '=' 30 %
P15735 BXGT008151 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform reviewed Kinase PHKG2 Residual Activity '=' 77 %
Q86Y07 BXGT017631 Serine/threonine-protein kinase VRK2 reviewed Kinase VRK2 Residual Activity '=' 78 %
P24723 BXGT008989 Protein kinase C eta type reviewed Kinase PRKCH Residual Activity '=' 86 %
Q9UIK4 BXGT021720 Death-associated protein kinase 2 reviewed Kinase DAPK2 Residual Activity '=' 87 %
Q99683 BXGT019947 Mitogen-activated protein kinase kinase kinase 5 reviewed Kinase MAP3K5 Residual Activity '=' 5 %
P08631 BXGT006801 Tyrosine-protein kinase HCK reviewed Kinase HCK Residual Activity '=' 57 %
P02545 BXGT005889 Prelamin-A/C reviewed - LMNA Potency '=' 5 nM
Q9NWZ3 BXGT021239 Interleukin-1 receptor-associated kinase 4 reviewed Kinase IRAK4 Residual Activity '=' 11 %
Q9H422 BXGT020469 Homeodomain-interacting protein kinase 3 reviewed Kinase HIPK3 Residual Activity '=' 19 %
O96017 BXGT005415 Serine/threonine-protein kinase Chk2 reviewed Kinase CHEK2 Residual Activity '=' 29 %
P45983 BXGT010494 Mitogen-activated protein kinase 8 reviewed Kinase MAPK8 Residual Activity '=' 33 %
O75716 BXGT005147 Serine/threonine-protein kinase 16 reviewed Kinase STK16 Kd '=' 510 nM
Q16539 BXGT013634 Mitogen-activated protein kinase 14 reviewed Kinase MAPK14 Kd - - -
P17612 BXGT008322 cAMP-dependent protein kinase catalytic subunit alpha reviewed Kinase PRKACA Activity '=' 80 %
P07333 BXGT006602 Macrophage colony-stimulating factor 1 receptor reviewed Kinase CSF1R Ki '=' 125 nM
Q96SB4 BXGT019740 SRSF protein kinase 1 reviewed Kinase SRPK1 Ki '>' 7943 nM
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A reviewed - KMT2A Potency '=' 35481 nM
O00255 BXGT003903 Menin reviewed - MEN1 Potency '=' 35481 nM
O00444 BXGT003921 Serine/threonine-protein kinase PLK4 reviewed Kinase PLK4 Kd '=' 770 nM
P06213 BXGT006425 Insulin receptor reviewed Kinase INSR Kd - - -
O75914 BXGT005165 Serine/threonine-protein kinase PAK 3 reviewed Kinase PAK3 Kd - - -
Q9UQB9 BXGT021810 Aurora kinase C reviewed Kinase AURKC Activity '=' 20 %
Q9H2K8 BXGT020455 Serine/threonine-protein kinase TAO3 reviewed Kinase TAOK3 Residual Activity '=' 69 %
Q13976 BXGT013409 cGMP-dependent protein kinase 1 reviewed Kinase PRKG1 Residual Activity '=' 60 %
P05771 BXGT006384 Protein kinase C beta type reviewed Kinase PRKCB Residual Activity '=' 104 %
P42680 BXGT010329 Tyrosine-protein kinase Tec reviewed Kinase TEC Residual Activity '=' 89 %
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase reviewed Kinase AKT1 Residual Activity '=' 113 %
Q9UEE5 BXGT021671 Serine/threonine-protein kinase 17A reviewed Kinase STK17A Kd '=' 2100 nM
Q00536 BXGT012535 Cyclin-dependent kinase 16 reviewed Kinase CDK16 Kd '=' 180 nM
Q13555 BXGT013375 Calcium/calmodulin-dependent protein kinase type II subunit gamma reviewed Kinase CAMK2G Kd - - -
P04629 BXGT006239 High affinity nerve growth factor receptor reviewed Kinase NTRK1 Kd - - -
P41240 BXGT010242 Tyrosine-protein kinase CSK reviewed Kinase CSK Kd - - -
O60674 BXGT004892 Tyrosine-protein kinase JAK2 reviewed Kinase JAK2 Kd - - -
P49760 BXGT010735 Dual specificity protein kinase CLK2 reviewed Kinase CLK2 Kd '=' 300 nM
P11362 BXGT007693 Fibroblast growth factor receptor 1 reviewed Kinase FGFR1 Kd - - -
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 reviewed Kinase KDR Kd - - -
P35916 BXGT009881 Vascular endothelial growth factor receptor 3 reviewed Kinase FLT4 Kd - - -
P49798 BXGT010745 Regulator of G-protein signaling 4 reviewed Enzyme modulator RGS4 Potency - 37685 nM
O43781 BXGT004625 Dual specificity tyrosine-phosphorylation-regulated kinase 3 reviewed Kinase DYRK3 Ki '=' 316 nM
Q15139 BXGT013546 Serine/threonine-protein kinase D1 reviewed Kinase PRKD1 Activity '=' 26 %
P27361 BXGT009176 Mitogen-activated protein kinase 3 reviewed Kinase MAPK3 Activity '=' 89 %
O15075 BXGT004124 Serine/threonine-protein kinase DCLK1 reviewed Kinase DCLK1 Ki '>' 10000 nM
Q9H2K8 BXGT020455 Serine/threonine-protein kinase TAO3 reviewed Kinase TAOK3 Residual Activity '=' 27 %
P51817 BXGT010895 cAMP-dependent protein kinase catalytic subunit PRKX reviewed Kinase PRKX Residual Activity '=' 70 %
Q8TF76 BXGT018826 Serine/threonine-protein kinase haspin reviewed Kinase HASPIN Residual Activity '=' 10 %
P41743 BXGT010270 Protein kinase C iota type reviewed Kinase PRKCI Residual Activity '=' 117 %
P51956 BXGT010909 Serine/threonine-protein kinase Nek3 reviewed Kinase NEK3 Residual Activity '=' 79 %
P27361 BXGT009176 Mitogen-activated protein kinase 3 reviewed Kinase MAPK3 Residual Activity '=' 72 %
Q9NRP7 BXGT021192 Serine/threonine-protein kinase 36 reviewed Kinase STK36 Kd - - -
P17405 BXGT008304 Sphingomyelin phosphodiesterase reviewed Enzyme SMPD1 Potency - 25118 nM
Q3U3Q1 BXGT014526 Serine/threonine-protein kinase ULK3 reviewed - Ulk3 Kd '=' 680 nM
Q13555 BXGT013375 Calcium/calmodulin-dependent protein kinase type II subunit gamma reviewed Kinase CAMK2G Ki '=' 1584 nM
Q96KQ7 BXGT019687 Histone-lysine N-methyltransferase EHMT2 reviewed Epigenetic regulator EHMT2 Potency - 12589 nM
P78368 BXGT011840 Casein kinase I isoform gamma-2 reviewed Kinase CSNK1G2 Ki '=' 1995 nM
Q9HCP0 BXGT020536 Casein kinase I isoform gamma-1 reviewed Kinase CSNK1G1 Ki '>' 6309 nM
P04629 BXGT006239 High affinity nerve growth factor receptor reviewed Kinase NTRK1 Residual Activity '=' -1 %
P35916 BXGT009881 Vascular endothelial growth factor receptor 3 reviewed Kinase FLT4 Residual Activity '=' 0 %
O89049 BXGT005293 Thioredoxin reductase 1, cytoplasmic reviewed - Txnrd1 Potency - 2511 nM
Q15349 BXGT013558 Ribosomal protein S6 kinase alpha-2 reviewed Kinase RPS6KA2 Residual Activity '=' 58 %
P05129 BXGT006322 Protein kinase C gamma type reviewed Kinase PRKCG Residual Activity '=' 73 %
P42345 BXGT010304 Serine/threonine-protein kinase mTOR reviewed Kinase MTOR Residual Activity '=' 84 %
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 AC50 '=' 3981 nM
P36897 BXGT009941 TGF-beta receptor type-1 reviewed Kinase TGFBR1 Residual Activity '=' 74 %
P42345 BXGT010304 Serine/threonine-protein kinase mTOR reviewed Kinase MTOR Residual Activity '=' 120 %
Q96BR1 BXGT019627 Serine/threonine-protein kinase Sgk3 reviewed - SGK3 Residual Activity '=' 58 %
Q96SB4 BXGT019740 SRSF protein kinase 1 reviewed Kinase SRPK1 Residual Activity '=' 87 %
Q9UK32 BXGT021736 Ribosomal protein S6 kinase alpha-6 reviewed Kinase RPS6KA6 Residual Activity '=' 52 %
P08069 BXGT006723 Insulin-like growth factor 1 receptor reviewed Kinase IGF1R Residual Activity '=' 49 %
P51812 BXGT010893 Ribosomal protein S6 kinase alpha-3 reviewed Kinase RPS6KA3 Residual Activity '=' 32 %
O60674 BXGT004892 Tyrosine-protein kinase JAK2 reviewed Kinase JAK2 Residual Activity '=' 11 %
P29317 BXGT009331 Ephrin type-A receptor 2 reviewed Kinase EPHA2 Ki '>' 3162 nM
Q9UQB9 BXGT021810 Aurora kinase C reviewed Kinase AURKC Kd '=' 5300 nM
P00533 BXGT005575 Epidermal growth factor receptor reviewed Kinase EGFR Kd - - -
P15735 BXGT008151 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform reviewed Kinase PHKG2 Kd '=' 480 nM
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 AC50 '=' 15 nM
P42345 BXGT010304 Serine/threonine-protein kinase mTOR reviewed Kinase MTOR Potency '=' 20749 nM
P51957 BXGT010910 Serine/threonine-protein kinase Nek4 reviewed Kinase NEK4 Ki '=' 1000 nM
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 Potency '=' 398 nM
Q15418 BXGT013569 Ribosomal protein S6 kinase alpha-1 reviewed Kinase RPS6KA1 Activity '=' 55 %
Q15759 BXGT013595 Mitogen-activated protein kinase 11 reviewed Kinase MAPK11 Activity '=' 106 %
Q02750 BXGT012662 Dual specificity mitogen-activated protein kinase kinase 1 reviewed Kinase MAP2K1 Activity '=' 58 %
Q9H2X6 BXGT020458 Homeodomain-interacting protein kinase 2 reviewed Kinase HIPK2 Ki '=' 199 nM
Q9H3Y6 BXGT020468 Tyrosine-protein kinase Srms reviewed Kinase SRMS Ki '>' 1584 nM
Q9H2G2 BXGT020452 STE20-like serine/threonine-protein kinase reviewed Kinase SLK Ki '=' 3162 nM
Q07912 BXGT012947 Activated CDC42 kinase 1 reviewed Kinase TNK2 Residual Activity '=' 50 %
P52564 BXGT010932 Dual specificity mitogen-activated protein kinase kinase 6 reviewed Kinase MAP2K6 Residual Activity '=' 13 %
Q02750 BXGT012662 Dual specificity mitogen-activated protein kinase kinase 1 reviewed Kinase MAP2K1 Residual Activity '=' 50 %
O14757 BXGT004092 Serine/threonine-protein kinase Chk1 reviewed Kinase CHEK1 Residual Activity '=' 32 %
Q8TDC3 BXGT018808 Serine/threonine-protein kinase BRSK1 reviewed Kinase BRSK1 Residual Activity '=' 38 %
P11309 BXGT007685 Serine/threonine-protein kinase pim-1 reviewed Kinase PIM1 Residual Activity '=' 68 %
P34947 BXGT009774 G protein-coupled receptor kinase 5 reviewed Kinase GRK5 Residual Activity '=' 63 %
P07333 BXGT006602 Macrophage colony-stimulating factor 1 receptor reviewed Kinase CSF1R Residual Activity '=' 9 %
Q8TF76 BXGT018826 Serine/threonine-protein kinase haspin reviewed Kinase HASPIN Residual Activity '=' -1 %
P12931 BXGT007859 Proto-oncogene tyrosine-protein kinase Src reviewed Kinase SRC Residual Activity '=' 64 %
Q15139 BXGT013546 Serine/threonine-protein kinase D1 reviewed Kinase PRKD1 Residual Activity '=' 32 %
Q13554 BXGT013374 Calcium/calmodulin-dependent protein kinase type II subunit beta reviewed Kinase CAMK2B Residual Activity '=' 8 %
P29320 BXGT009332 Ephrin type-A receptor 3 reviewed Kinase EPHA3 Residual Activity '=' 75 %
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 reviewed Kinase FLT1 Residual Activity '=' 2 %
P45983 BXGT010494 Mitogen-activated protein kinase 8 reviewed Kinase MAPK8 Residual Activity '=' 5 %
Q15418 BXGT013569 Ribosomal protein S6 kinase alpha-1 reviewed Kinase RPS6KA1 Residual Activity '=' 86 %
P07947 BXGT006701 Tyrosine-protein kinase Yes reviewed Kinase YES1 Residual Activity '=' 98 %
Q16566 BXGT013639 Calcium/calmodulin-dependent protein kinase type IV reviewed Kinase CAMK4 Residual Activity '=' 73 %
P07948 BXGT006702 Tyrosine-protein kinase Lyn reviewed Kinase LYN Residual Activity '=' 30 %
P28482 BXGT009263 Mitogen-activated protein kinase 1 reviewed Kinase MAPK1 Ki '=' 5011 nM
Q9JI10 BXGT020811 Serine/threonine-protein kinase 3 reviewed - Stk3 Kd '=' 220 nM
P45983 BXGT010494 Mitogen-activated protein kinase 8 reviewed Kinase MAPK8 Kd '=' 100 nM
Q96GD4 BXGT019667 Aurora kinase B reviewed Kinase AURKB Residual Activity '=' 0 %
Q9NYY3 BXGT021264 Serine/threonine-protein kinase PLK2 reviewed Kinase PLK2 Residual Activity '=' 85 %
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 8912 nM
Q9UM73 BXGT021773 ALK tyrosine kinase receptor reviewed Kinase ALK Residual Activity '=' 29 %
Q12866 BXGT013273 Tyrosine-protein kinase Mer reviewed Kinase MERTK Residual Activity '=' 22 %
P54764 BXGT011078 Ephrin type-A receptor 4 reviewed Kinase EPHA4 Residual Activity '=' 105 %
O75676 BXGT005144 Ribosomal protein S6 kinase alpha-4 reviewed Kinase RPS6KA4 Residual Activity '=' 36 %
Q13464 BXGT013357 Rho-associated protein kinase 1 reviewed Kinase ROCK1 Residual Activity '=' 95 %
P05771 BXGT006384 Protein kinase C beta type reviewed Kinase PRKCB Residual Activity '=' 102 %
Q13464 BXGT013357 Rho-associated protein kinase 1 reviewed Kinase ROCK1 Residual Activity '=' 122 %
O96020 BXGT005416 G1/S-specific cyclin-E2 reviewed Enzyme modulator CCNE2 Residual Activity '=' 8 %
P24941 BXGT009002 Cyclin-dependent kinase 2 reviewed Kinase CDK2 Residual Activity '=' 8 %
P24864 BXGT009000 G1/S-specific cyclin-E1 reviewed Enzyme modulator CCNE1 Residual Activity '=' 8 %
P49760 BXGT010735 Dual specificity protein kinase CLK2 reviewed Kinase CLK2 Residual Activity '=' 21 %
P06241 BXGT006429 Tyrosine-protein kinase Fyn reviewed Kinase FYN Residual Activity '=' 47 %
P51617 BXGT010868 Interleukin-1 receptor-associated kinase 1 reviewed Kinase IRAK1 Residual Activity '=' 69 %
Q09013 BXGT013023 Myotonin-protein kinase reviewed Kinase DMPK Residual Activity '=' 113 %
O60285 BXGT004867 NUAK family SNF1-like kinase 1 reviewed Kinase NUAK1 Residual Activity '=' 28 %
P00533 BXGT005575 Epidermal growth factor receptor reviewed Kinase EGFR Ki '>' 1995 nM
Q05397 BXGT012815 Focal adhesion kinase 1 reviewed Kinase PTK2 Residual Activity '=' 9 %
Q13526 BXGT013369 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 reviewed - PIN1 Potency - 22387 nM
Q8N4C8 BXGT018510 Misshapen-like kinase 1 reviewed Kinase MINK1 Residual Activity '=' 86 %
Q02763 BXGT012667 Angiopoietin-1 receptor reviewed Kinase TEK Residual Activity '=' 63 %
P07947 BXGT006701 Tyrosine-protein kinase Yes reviewed Kinase YES1 Residual Activity '=' 51 %
P53779 BXGT011014 Mitogen-activated protein kinase 10 reviewed Kinase MAPK10 Residual Activity '=' 5 %
Q15831 BXGT013604 Serine/threonine-protein kinase STK11 reviewed Kinase STK11 Residual Activity '=' 41 %
Q8N4C8 BXGT018510 Misshapen-like kinase 1 reviewed Kinase MINK1 Residual Activity '=' 50 %
P09769 BXGT006917 Tyrosine-protein kinase Fgr reviewed Kinase FGR Residual Activity '=' 38 %
Q14289 BXGT013459 Protein-tyrosine kinase 2-beta reviewed Kinase PTK2B Residual Activity '=' 68 %
O14757 BXGT004092 Serine/threonine-protein kinase Chk1 reviewed Kinase CHEK1 Residual Activity '=' 72 %
P39748 BXGT010134 Flap endonuclease 1 reviewed Enzyme FEN1 Potency - 2993 nM
Q16539 BXGT013634 Mitogen-activated protein kinase 14 reviewed Kinase MAPK14 Residual Activity '=' 85 %
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase reviewed - APEX1 Potency - 17782 nM
Q13043 BXGT013307 Serine/threonine-protein kinase 4 reviewed Kinase STK4 Residual Activity '=' 21 %
Q9HC98 BXGT020528 Serine/threonine-protein kinase Nek6 reviewed Kinase NEK6 Residual Activity '=' 101 %
P54762 BXGT011076 Ephrin type-B receptor 1 reviewed Kinase EPHB1 Residual Activity '=' 91 %
Q13557 BXGT013376 Calcium/calmodulin-dependent protein kinase type II subunit delta reviewed Kinase CAMK2D Residual Activity '=' 43 %
P52564 BXGT010932 Dual specificity mitogen-activated protein kinase kinase 6 reviewed Kinase MAP2K6 Residual Activity '=' 82 %
P08631 BXGT006801 Tyrosine-protein kinase HCK reviewed Kinase HCK Residual Activity '=' 27 %
P14635 BXGT008031 G2/mitotic-specific cyclin-B1 reviewed Enzyme modulator CCNB1 Residual Activity '=' 35 %
P06493 BXGT006445 Cyclin-dependent kinase 1 reviewed Kinase CDK1 Residual Activity '=' 35 %
Q9Y6M4 BXGT022335 Casein kinase I isoform gamma-3 reviewed Kinase CSNK1G3 Residual Activity '=' 83 %
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase reviewed Kinase AKT1 Activity '=' 97 %
P06239 BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK Ki '=' 1995 nM
O75582 BXGT005137 Ribosomal protein S6 kinase alpha-5 reviewed Kinase RPS6KA5 Residual Activity '=' 93 %
P29597 BXGT009367 Non-receptor tyrosine-protein kinase TYK2 reviewed Kinase TYK2 Ki '=' 1258 nM
P21802 BXGT008691 Fibroblast growth factor receptor 2 reviewed Kinase FGFR2 Residual Activity '=' 12 %
P22607 BXGT008784 Fibroblast growth factor receptor 3 reviewed Kinase FGFR3 Residual Activity '=' 40 %
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 11220 nM
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 reviewed Kinase KDR Residual Activity '=' 17 %
P04049 BXGT006133 RAF proto-oncogene serine/threonine-protein kinase reviewed Kinase RAF1 Residual Activity '=' 61 %
Q8IYT8 BXGT018370 Serine/threonine-protein kinase ULK2 reviewed Kinase ULK2 Residual Activity '=' 90 %
Q96RG2 BXGT019726 PAS domain-containing serine/threonine-protein kinase reviewed Kinase PASK Residual Activity '=' 125 %
P11309 BXGT007685 Serine/threonine-protein kinase pim-1 reviewed Kinase PIM1 Residual Activity '=' 18 %
O15264 BXGT004144 Mitogen-activated protein kinase 13 reviewed Kinase MAPK13 Residual Activity '=' 73 %
Q86V86 BXGT017617 Serine/threonine-protein kinase pim-3 reviewed - PIM3 Residual Activity '=' 59 %
P80192 BXGT011883 Mitogen-activated protein kinase kinase kinase 9 reviewed Kinase MAP3K9 Residual Activity '=' 13 %
Q14012 BXGT013437 Calcium/calmodulin-dependent protein kinase type 1 reviewed Kinase CAMK1 Residual Activity '=' 77 %
P30530 BXGT009431 Tyrosine-protein kinase receptor UFO reviewed Kinase AXL Residual Activity '=' 50 %
Q13464 BXGT013357 Rho-associated protein kinase 1 reviewed Kinase ROCK1 Ki '=' 1995 nM
Q7KZI7 BXGT016990 Serine/threonine-protein kinase MARK2 reviewed Kinase MARK2 Kd '=' 1800 nM
Q9P1W9 BXGT021296 Serine/threonine-protein kinase pim-2 reviewed Kinase PIM2 Kd '=' 460 nM
P33981 BXGT009744 Dual specificity protein kinase TTK reviewed Kinase TTK IC50 '=' 2500 nM
Q96RR4 BXGT019734 Calcium/calmodulin-dependent protein kinase kinase 2 reviewed Kinase CAMKK2 Activity '=' 41 %
Q96GD4 BXGT019667 Aurora kinase B reviewed Kinase AURKB Activity '=' 15 %
Q96KB5 BXGT019685 Lymphokine-activated killer T-cell-originated protein kinase reviewed Kinase PBK Ki '=' 1000 nM
Q13554 BXGT013374 Calcium/calmodulin-dependent protein kinase type II subunit beta reviewed Kinase CAMK2B Ki '=' 6309 nM
Q9HBH9 BXGT020521 MAP kinase-interacting serine/threonine-protein kinase 2 reviewed Kinase MKNK2 Ki '=' 316 nM
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 29092 nM
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 Potency '=' 31622 nM
Q9HBY8 BXGT020524 Serine/threonine-protein kinase Sgk2 reviewed Kinase SGK2 Residual Activity '=' 33 %
Q16832 BXGT013678 Discoidin domain-containing receptor 2 reviewed Kinase DDR2 Residual Activity '=' 92 %
P80192 BXGT011883 Mitogen-activated protein kinase kinase kinase 9 reviewed Kinase MAP3K9 Residual Activity '=' 4 %
P45983 BXGT010494 Mitogen-activated protein kinase 8 reviewed Kinase MAPK8 Activity '=' 23 %
P27361 BXGT009176 Mitogen-activated protein kinase 3 reviewed Kinase MAPK3 Residual Activity '=' 59 %
P78368 BXGT011840 Casein kinase I isoform gamma-2 reviewed Kinase CSNK1G2 Residual Activity '=' 70 %
P50750 BXGT010818 Cyclin-dependent kinase 9 reviewed Kinase CDK9 Residual Activity '=' 96 %
O60563 BXGT004883 Cyclin-T1 reviewed Enzyme modulator CCNT1 Residual Activity '=' 96 %
P42685 BXGT010332 Tyrosine-protein kinase FRK reviewed Kinase FRK Residual Activity '=' 91 %
Q9BYP7 BXGT020188 Serine/threonine-protein kinase WNK3 reviewed Kinase WNK3 Residual Activity '=' 77 %
O94806 BXGT005335 Serine/threonine-protein kinase D3 reviewed Kinase PRKD3 Ki '=' 100 nM
P23443 BXGT008866 Ribosomal protein S6 kinase beta-1 reviewed Kinase RPS6KB1 Ki '=' 125 nM
P29322 BXGT009333 Ephrin type-A receptor 8 reviewed Kinase EPHA8 Kd - - -
Q9UQB9 BXGT021810 Aurora kinase C reviewed Kinase AURKC Residual Activity '=' 9 %
P14616 BXGT008026 Insulin receptor-related protein reviewed Kinase INSRR Residual Activity '=' 102 %
P50613 BXGT010815 Cyclin-dependent kinase 7 reviewed Kinase CDK7 Residual Activity '=' 24 %
P51946 BXGT010907 Cyclin-H reviewed Enzyme modulator CCNH Residual Activity '=' 24 %
Q15746 BXGT013591 Myosin light chain kinase, smooth muscle reviewed Kinase MYLK Residual Activity '=' 3 %
Q9NYY3 BXGT021264 Serine/threonine-protein kinase PLK2 reviewed Kinase PLK2 Residual Activity '=' 61 %
Q13177 BXGT013323 Serine/threonine-protein kinase PAK 2 reviewed Kinase PAK2 Residual Activity '=' 96 %
O94804 BXGT005334 Serine/threonine-protein kinase 10 reviewed Kinase STK10 Residual Activity '=' 87 %
P09619 BXGT006911 Platelet-derived growth factor receptor beta reviewed Kinase PDGFRB Residual Activity '=' 99 %
Q96PF2 BXGT019708 Testis-specific serine/threonine-protein kinase 2 reviewed Kinase TSSK2 Residual Activity '=' 92 %
Q7L7X3 BXGT016997 Serine/threonine-protein kinase TAO1 reviewed Kinase TAOK1 Residual Activity '=' 69 %
O75116 BXGT005100 Rho-associated protein kinase 2 reviewed Kinase ROCK2 Residual Activity '=' 39 %
Q14289 BXGT013459 Protein-tyrosine kinase 2-beta reviewed Kinase PTK2B Residual Activity '=' 23 %
P06239 BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK Residual Activity '=' 70 %
Q9BZL6 BXGT020199 Serine/threonine-protein kinase D2 reviewed Kinase PRKD2 Residual Activity '=' 36 %
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase reviewed - APEX1 Potency '=' 15848 nM
P78396 BXGT011842 Cyclin-A1 reviewed Enzyme modulator CCNA1 Activity '=' 50 %
P20248 BXGT008554 Cyclin-A2 reviewed Enzyme modulator CCNA2 Activity '=' 50 %
P24941 BXGT009002 Cyclin-dependent kinase 2 reviewed Kinase CDK2 Activity '=' 50 %
Q13188 BXGT013324 Serine/threonine-protein kinase 3 reviewed Kinase STK3 Ki '=' 316 nM
Q13188 BXGT013324 Serine/threonine-protein kinase 3 reviewed Kinase STK3 Activity '=' 31 %
Q8TD08 BXGT018803 Mitogen-activated protein kinase 15 reviewed Kinase MAPK15 Activity '=' 43 %
Q8N4C8 BXGT018510 Misshapen-like kinase 1 reviewed Kinase MINK1 Ki '=' 199 nM
Q8IW41 BXGT018352 MAP kinase-activated protein kinase 5 reviewed Kinase MAPKAPK5 Residual Activity '=' 14 %
Q15349 BXGT013558 Ribosomal protein S6 kinase alpha-2 reviewed Kinase RPS6KA2 Kd '=' 2200 nM
O75582 BXGT005137 Ribosomal protein S6 kinase alpha-5 reviewed Kinase RPS6KA5 Kd '=' 1700 nM
Q9P0L2 BXGT021289 Serine/threonine-protein kinase MARK1 reviewed Kinase MARK1 Residual Activity '=' 6 %
P42345 BXGT010304 Serine/threonine-protein kinase mTOR reviewed Kinase MTOR Residual Activity '=' 77 %
Q15759 BXGT013595 Mitogen-activated protein kinase 11 reviewed Kinase MAPK11 Residual Activity '=' 88 %
P05129 BXGT006322 Protein kinase C gamma type reviewed Kinase PRKCG Residual Activity '=' 30 %
P19525 BXGT008492 Interferon-induced, double-stranded RNA-activated protein kinase reviewed Kinase EIF2AK2 IC50 '=' 8000 nM
Q12851 BXGT013271 Mitogen-activated protein kinase kinase kinase kinase 2 reviewed Kinase MAP4K2 Ki '=' 50 nM
Q96RG2 BXGT019726 PAS domain-containing serine/threonine-protein kinase reviewed Kinase PASK Residual Activity '=' 81 %
O15111 BXGT004126 Inhibitor of nuclear factor kappa-B kinase subunit alpha reviewed Kinase CHUK Residual Activity '=' 57 %
P54756 BXGT011074 Ephrin type-A receptor 5 reviewed Kinase EPHA5 Residual Activity '=' 115 %
Q9Y3S1 BXGT022266 Serine/threonine-protein kinase WNK2 reviewed Kinase WNK2 Residual Activity '=' 79 %
P16234 BXGT008209 Platelet-derived growth factor receptor alpha reviewed Kinase PDGFRA Residual Activity '=' 86 %
P09619 BXGT006911 Platelet-derived growth factor receptor beta reviewed Kinase PDGFRB Residual Activity '=' 96 %
P08631 BXGT006801 Tyrosine-protein kinase HCK reviewed Kinase HCK Residual Activity '=' 80 %
P08069 BXGT006723 Insulin-like growth factor 1 receptor reviewed Kinase IGF1R Residual Activity '=' 105 %
Q13131 BXGT013314 5'-AMP-activated protein kinase catalytic subunit alpha-1 reviewed Kinase PRKAA1 Residual Activity '=' 64 %
Q9Y478 BXGT022271 5'-AMP-activated protein kinase subunit beta-1 reviewed Kinase PRKAB1 Residual Activity '=' 64 %
P54619 BXGT011060 5'-AMP-activated protein kinase subunit gamma-1 reviewed Kinase PRKAG1 Residual Activity '=' 64 %
P54760 BXGT011075 Ephrin type-B receptor 4 reviewed Kinase EPHB4 Residual Activity '=' 55 %
Q8IU85 BXGT018333 Calcium/calmodulin-dependent protein kinase type 1D reviewed Kinase CAMK1D Residual Activity '=' 70 %
O14920 BXGT004110 Inhibitor of nuclear factor kappa-B kinase subunit beta reviewed Kinase IKBKB Residual Activity '=' 43 %
O43353 BXGT004589 Receptor-interacting serine/threonine-protein kinase 2 reviewed Kinase RIPK2 Residual Activity '=' 70 %
P07949 BXGT006703 Proto-oncogene tyrosine-protein kinase receptor Ret reviewed Kinase RET Residual Activity '=' 11 %
P00519 BXGT005570 Tyrosine-protein kinase ABL1 reviewed Kinase ABL1 Residual Activity '=' 83 %
Q12851 BXGT013271 Mitogen-activated protein kinase kinase kinase kinase 2 reviewed Kinase MAP4K2 Residual Activity '=' 2 %
Q9UM73 BXGT021773 ALK tyrosine kinase receptor reviewed Kinase ALK Residual Activity '=' 61 %
P36888 BXGT009938 Receptor-type tyrosine-protein kinase FLT3 reviewed Kinase FLT3 Residual Activity '=' 6 %
P21802 BXGT008691 Fibroblast growth factor receptor 2 reviewed Kinase FGFR2 Residual Activity '=' 52 %
O75582 BXGT005137 Ribosomal protein S6 kinase alpha-5 reviewed Kinase RPS6KA5 Residual Activity '=' 69 %
O15146 BXGT004131 Muscle, skeletal receptor tyrosine-protein kinase reviewed Kinase MUSK Residual Activity '=' 24 %
O15111 BXGT004126 Inhibitor of nuclear factor kappa-B kinase subunit alpha reviewed Kinase CHUK Residual Activity '=' 21 %
P45983 BXGT010494 Mitogen-activated protein kinase 8 reviewed Kinase MAPK8 IC50 '>=' 50000 nM
P53350 BXGT010984 Serine/threonine-protein kinase PLK1 reviewed Kinase PLK1 Ki '>' 7943 nM
P11940 BXGT007762 Polyadenylate-binding protein 1 reviewed - PABPC1 IC50 '>' 66000 nM
Q13627 BXGT013385 Dual specificity tyrosine-phosphorylation-regulated kinase 1A reviewed Kinase DYRK1A Activity '=' 40 %
Q92630 BXGT019360 Dual specificity tyrosine-phosphorylation-regulated kinase 2 reviewed Kinase DYRK2 Residual Activity '=' 4 %
Q13148 BXGT013318 TAR DNA-binding protein 43 reviewed - TARDBP Potency - 6309 nM
Q15303 BXGT013557 Receptor tyrosine-protein kinase erbB-4 reviewed Kinase ERBB4 Ki '=' 3981 nM
Q9BXA7 BXGT020164 Testis-specific serine/threonine-protein kinase 1 reviewed Kinase TSSK1B Residual Activity '=' 75 %
O00418 BXGT003918 Eukaryotic elongation factor 2 kinase reviewed Kinase EEF2K Residual Activity '=' 92 %
P43405 BXGT010386 Tyrosine-protein kinase SYK reviewed Kinase SYK Residual Activity '=' 73 %
P45984 BXGT010495 Mitogen-activated protein kinase 9 reviewed Kinase MAPK9 Residual Activity '=' 26 %
P50750 BXGT010818 Cyclin-dependent kinase 9 reviewed Kinase CDK9 Residual Activity '=' 55 %
O60563 BXGT004883 Cyclin-T1 reviewed Enzyme modulator CCNT1 Residual Activity '=' 55 %
Q9Y5S2 BXGT022301 Serine/threonine-protein kinase MRCK beta reviewed Kinase CDC42BPB Residual Activity '=' 95 %
Q9UQB9 BXGT021810 Aurora kinase C reviewed Kinase AURKC Residual Activity '=' 4 %
P36896 BXGT009940 Activin receptor type-1B reviewed Kinase ACVR1B Residual Activity '=' 84 %
Q9H422 BXGT020469 Homeodomain-interacting protein kinase 3 reviewed Kinase HIPK3 Residual Activity '=' 73 %
P17252 BXGT008294 Protein kinase C alpha type reviewed Kinase PRKCA Residual Activity '=' 73 %
P11309 BXGT007685 Serine/threonine-protein kinase pim-1 reviewed Kinase PIM1 Ki '=' 501 nM
P06213 BXGT006425 Insulin receptor reviewed Kinase INSR Residual Activity '=' 81 %
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 26608 nM
Q9UPE1 BXGT021796 SRSF protein kinase 3 reviewed Kinase SRPK3 Residual Activity '=' 82 %
P43403 BXGT010385 Tyrosine-protein kinase ZAP-70 reviewed Kinase ZAP70 Residual Activity '=' 98 %
P31751 BXGT009576 RAC-beta serine/threonine-protein kinase reviewed Kinase AKT2 Residual Activity '=' 105 %
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 Potency '=' 3981 nM
O96020 BXGT005416 G1/S-specific cyclin-E2 reviewed Enzyme modulator CCNE2 Residual Activity '=' 3 %
P24941 BXGT009002 Cyclin-dependent kinase 2 reviewed Kinase CDK2 Residual Activity '=' 3 %
P24864 BXGT009000 G1/S-specific cyclin-E1 reviewed Enzyme modulator CCNE1 Residual Activity '=' 3 %
P21709 BXGT008685 Ephrin type-A receptor 1 reviewed Kinase EPHA1 Residual Activity '=' 67 %
P53350 BXGT010984 Serine/threonine-protein kinase PLK1 reviewed Kinase PLK1 Residual Activity '=' 64 %
Q8IW41 BXGT018352 MAP kinase-activated protein kinase 5 reviewed Kinase MAPKAPK5 Residual Activity '=' 59 %
Q13555 BXGT013375 Calcium/calmodulin-dependent protein kinase type II subunit gamma reviewed Kinase CAMK2G Residual Activity '=' 8 %
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 reviewed Kinase FLT1 Residual Activity '=' 26 %
P11362 BXGT007693 Fibroblast growth factor receptor 1 reviewed Kinase FGFR1 Residual Activity '=' 4 %
P15735 BXGT008151 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform reviewed Kinase PHKG2 Ki '=' 630 nM
Q13557 BXGT013376 Calcium/calmodulin-dependent protein kinase type II subunit delta reviewed Kinase CAMK2D Ki '=' 1000 nM
O14757 BXGT004092 Serine/threonine-protein kinase Chk1 reviewed Kinase CHEK1 Ki '=' 1258 nM
Q9Y253 BXGT022216 DNA polymerase eta reviewed - POLH Potency - 22387 nM
Q9Y6E0 BXGT022327 Serine/threonine-protein kinase 24 reviewed Kinase STK24 Residual Activity '=' 21 %
P53779 BXGT011014 Mitogen-activated protein kinase 10 reviewed Kinase MAPK10 Residual Activity '=' -6 %
P24723 BXGT008989 Protein kinase C eta type reviewed Kinase PRKCH Residual Activity '=' 82 %
Q16539 BXGT013634 Mitogen-activated protein kinase 14 reviewed Kinase MAPK14 Residual Activity '=' 96 %
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 19952 nM
P41743 BXGT010270 Protein kinase C iota type reviewed Kinase PRKCI Residual Activity '=' 107 %
Q02156 BXGT012639 Protein kinase C epsilon type reviewed Kinase PRKCE Residual Activity '=' 101 %
P42680 BXGT010329 Tyrosine-protein kinase Tec reviewed Kinase TEC Residual Activity '=' 57 %
P22455 BXGT008772 Fibroblast growth factor receptor 4 reviewed Kinase FGFR4 Residual Activity '=' 89 %
Q12851 BXGT013271 Mitogen-activated protein kinase kinase kinase kinase 2 reviewed Kinase MAP4K2 Residual Activity '=' 16 %
P53355 BXGT010985 Death-associated protein kinase 1 reviewed Kinase DAPK1 Residual Activity '=' 68 %
Q00526 BXGT012531 Cyclin-dependent kinase 3 reviewed Kinase CDK3 Residual Activity '=' 26 %
O96020 BXGT005416 G1/S-specific cyclin-E2 reviewed Enzyme modulator CCNE2 Residual Activity '=' 26 %
P24864 BXGT009000 G1/S-specific cyclin-E1 reviewed Enzyme modulator CCNE1 Residual Activity '=' 26 %
Q9NQU5 BXGT021169 Serine/threonine-protein kinase PAK 6 reviewed - PAK6 Residual Activity '=' 49 %
Q86UE8 BXGT017612 Serine/threonine-protein kinase tousled-like 2 reviewed Kinase TLK2 Residual Activity '=' 71 %
Q9Y5S2 BXGT022301 Serine/threonine-protein kinase MRCK beta reviewed Kinase CDC42BPB Residual Activity '=' 90 %
Q5VT25 BXGT015887 Serine/threonine-protein kinase MRCK alpha reviewed Kinase CDC42BPA Residual Activity '=' 116 %
P45983 BXGT010494 Mitogen-activated protein kinase 8 reviewed Kinase MAPK8 IC50 '=' 14000 nM
P16234 BXGT008209 Platelet-derived growth factor receptor alpha reviewed Kinase PDGFRA Residual Activity '=' 108 %
Q91Y86 BXGT019324 Mitogen-activated protein kinase 8 reviewed - Mapk8 Inhibition - - -
Q9HAZ1 BXGT020511 Dual specificity protein kinase CLK4 reviewed - CLK4 Ki '=' 63 nM
P16591 BXGT008246 Tyrosine-protein kinase Fer reviewed Kinase FER Ki '=' 50 nM
P78396 BXGT011842 Cyclin-A1 reviewed Enzyme modulator CCNA1 Residual Activity '=' 36 %
P20248 BXGT008554 Cyclin-A2 reviewed Enzyme modulator CCNA2 Residual Activity '=' 36 %
P24941 BXGT009002 Cyclin-dependent kinase 2 reviewed Kinase CDK2 Residual Activity '=' 36 %
Q15831 BXGT013604 Serine/threonine-protein kinase STK11 reviewed Kinase STK11 Residual Activity '=' 75 %
Q13177 BXGT013323 Serine/threonine-protein kinase PAK 2 reviewed Kinase PAK2 Residual Activity '=' 86 %
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 reviewed Kinase FLT1 Ki '=' 199 nM
P22607 BXGT008784 Fibroblast growth factor receptor 3 reviewed Kinase FGFR3 Ki '=' 158 nM
Q13153 BXGT013319 Serine/threonine-protein kinase PAK 1 reviewed Kinase PAK1 Ki '>' 10000 nM
P16591 BXGT008246 Tyrosine-protein kinase Fer reviewed Kinase FER Residual Activity '=' 51 %
O89049 BXGT005293 Thioredoxin reductase 1, cytoplasmic reviewed - Txnrd1 Potency - 35481 nM
P27448 BXGT009183 MAP/microtubule affinity-regulating kinase 3 reviewed Kinase MARK3 Activity '=' 49 %
O75582 BXGT005137 Ribosomal protein S6 kinase alpha-5 reviewed Kinase RPS6KA5 Activity '=' 72 %
Q15746 BXGT013591 Myosin light chain kinase, smooth muscle reviewed Kinase MYLK Activity '=' 34 %
P00523 BXGT005572 Proto-oncogene tyrosine-protein kinase Src reviewed - SRC Activity '=' 89 %
O14757 BXGT004092 Serine/threonine-protein kinase Chk1 reviewed Kinase CHEK1 Activity '=' 63 %
Q16539 BXGT013634 Mitogen-activated protein kinase 14 reviewed Kinase MAPK14 Activity '=' 110 %
Q16620 BXGT013645 BDNF/NT-3 growth factors receptor reviewed Kinase NTRK2 Ki '=' 794 nM
Q9UPE1 BXGT021796 SRSF protein kinase 3 reviewed Kinase SRPK3 Residual Activity '=' 90 %
Q07912 BXGT012947 Activated CDC42 kinase 1 reviewed Kinase TNK2 Residual Activity '=' 12 %
Q06418 BXGT012875 Tyrosine-protein kinase receptor TYRO3 reviewed Kinase TYRO3 Ki '=' 1000 nM
Q14680 BXGT013499 Maternal embryonic leucine zipper kinase reviewed Kinase MELK Residual Activity '=' 13 %
Q09013 BXGT013023 Myotonin-protein kinase reviewed Kinase DMPK Residual Activity '=' 68 %
Q15375 BXGT013562 Ephrin type-A receptor 7 reviewed Kinase EPHA7 Residual Activity '=' 41 %
Q9UEE5 BXGT021671 Serine/threonine-protein kinase 17A reviewed Kinase STK17A Residual Activity '=' 2 %
Q12866 BXGT013273 Tyrosine-protein kinase Mer reviewed Kinase MERTK Residual Activity '=' 9 %
Q13557 BXGT013376 Calcium/calmodulin-dependent protein kinase type II subunit delta reviewed Kinase CAMK2D Kd - - -
Q9HC98 BXGT020528 Serine/threonine-protein kinase Nek6 reviewed Kinase NEK6 Kd - - -
O94804 BXGT005334 Serine/threonine-protein kinase 10 reviewed Kinase STK10 Kd - - -
O43353 BXGT004589 Receptor-interacting serine/threonine-protein kinase 2 reviewed Kinase RIPK2 Kd - - -
P54764 BXGT011078 Ephrin type-A receptor 4 reviewed Kinase EPHA4 Kd - - -
P24941 BXGT009002 Cyclin-dependent kinase 2 reviewed Kinase CDK2 Ki '=' 79 nM
Q15078 BXGT013534 Cyclin-dependent kinase 5 activator 1 reviewed Enzyme modulator CDK5R1 Residual Activity '=' 1 %
Q00535 BXGT012534 Cyclin-dependent-like kinase 5 reviewed Kinase CDK5 Residual Activity '=' 1 %
P22607 BXGT008784 Fibroblast growth factor receptor 3 reviewed Kinase FGFR3 Residual Activity '=' 72 %
P35916 BXGT009881 Vascular endothelial growth factor receptor 3 reviewed Kinase FLT4 Residual Activity '=' 2 %
Q16513 BXGT013632 Serine/threonine-protein kinase N2 reviewed Kinase PKN2 Residual Activity '=' 74 %
Q7L7X3 BXGT016997 Serine/threonine-protein kinase TAO1 reviewed Kinase TAOK1 Residual Activity '=' 25 %
Q9NQU5 BXGT021169 Serine/threonine-protein kinase PAK 6 reviewed - PAK6 Residual Activity '=' 91 %
P42345 BXGT010304 Serine/threonine-protein kinase mTOR reviewed Kinase MTOR Residual Activity '=' 104 %
Q8IU85 BXGT018333 Calcium/calmodulin-dependent protein kinase type 1D reviewed Kinase CAMK1D Kd '=' 1400 nM
O35235 BXGT004518 Tumor necrosis factor ligand superfamily member 11 reviewed - Tnfsf11 Inhibition - - -
Q15759 BXGT013595 Mitogen-activated protein kinase 11 reviewed Kinase MAPK11 Residual Activity '=' 79 %
Q13976 BXGT013409 cGMP-dependent protein kinase 1 reviewed Kinase PRKG1 Residual Activity '=' 79 %
Q01453 BXGT012588 Peripheral myelin protein 22 reviewed Cellular structure PMP22 Potency '=' 84921 nM
Q04912 BXGT012790 Macrophage-stimulating protein receptor reviewed Kinase MST1R Residual Activity '=' 51 %
P31751 BXGT009576 RAC-beta serine/threonine-protein kinase reviewed Kinase AKT2 Residual Activity '=' 104 %
P36897 BXGT009941 TGF-beta receptor type-1 reviewed Kinase TGFBR1 Residual Activity '=' 88 %
Q99700 BXGT019949 Ataxin-2 reviewed Nucleic acid binding ATXN2 Potency - 15848 nM
P78368 BXGT011840 Casein kinase I isoform gamma-2 reviewed Kinase CSNK1G2 Residual Activity '=' 6 %
Q15418 BXGT013569 Ribosomal protein S6 kinase alpha-1 reviewed Kinase RPS6KA1 Residual Activity '=' 64 %
Q8IW41 BXGT018352 MAP kinase-activated protein kinase 5 reviewed Kinase MAPKAPK5 Ki '>' 1584 nM
P08631 BXGT006801 Tyrosine-protein kinase HCK reviewed Kinase HCK Kd - - -
Q15759 BXGT013595 Mitogen-activated protein kinase 11 reviewed Kinase MAPK11 Kd - - -
P78368 BXGT011840 Casein kinase I isoform gamma-2 reviewed Kinase CSNK1G2 Kd - - -
Q9Y6M4 BXGT022335 Casein kinase I isoform gamma-3 reviewed Kinase CSNK1G3 Ki '=' 1000 nM
P11940 BXGT007762 Polyadenylate-binding protein 1 reviewed - PABPC1 IC50 '=' 30850 nM
P53778 BXGT011013 Mitogen-activated protein kinase 12 reviewed Kinase MAPK12 Residual Activity '=' 82 %
P29317 BXGT009331 Ephrin type-A receptor 2 reviewed Kinase EPHA2 Residual Activity '=' 88 %
O96013 BXGT005414 Serine/threonine-protein kinase PAK 4 reviewed Kinase PAK4 Residual Activity '=' 88 %
Q6PHR2 BXGT016467 Serine/threonine-protein kinase ULK3 reviewed Kinase ULK3 Residual Activity '=' 43 %
Q96GD4 BXGT019667 Aurora kinase B reviewed Kinase AURKB Ki '=' 10 nM
O15648 BXGT004185 ATP-dependent 6-phosphofructokinase reviewed - pfk Potency - 42561 nM
P63092 BXGT011495 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short reviewed - GNAS Potency - 50118 nM
O14920 BXGT004110 Inhibitor of nuclear factor kappa-B kinase subunit beta reviewed Kinase IKBKB Residual Activity '=' 78 %
P17612 BXGT008322 cAMP-dependent protein kinase catalytic subunit alpha reviewed Kinase PRKACA Residual Activity '=' 89 %
Q04759 BXGT012781 Protein kinase C theta type reviewed Kinase PRKCQ Residual Activity '=' 76 %
Q8IU85 BXGT018333 Calcium/calmodulin-dependent protein kinase type 1D reviewed Kinase CAMK1D Residual Activity '=' 38 %
P53667 BXGT011008 LIM domain kinase 1 reviewed Kinase LIMK1 Residual Activity '=' 30 %
Q8TDX7 BXGT018817 Serine/threonine-protein kinase Nek7 reviewed Kinase NEK7 Residual Activity '=' 89 %
P27448 BXGT009183 MAP/microtubule affinity-regulating kinase 3 reviewed Kinase MARK3 Ki '=' 3 nM
P08581 BXGT006794 Hepatocyte growth factor receptor reviewed Kinase MET Residual Activity '=' 87 %
Q16566 BXGT013639 Calcium/calmodulin-dependent protein kinase type IV reviewed Kinase CAMK4 Residual Activity '=' 24 %
P42684 BXGT010331 Tyrosine-protein kinase ABL2 reviewed Kinase ABL2 Residual Activity '=' 87 %
P06239 BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK Residual Activity '=' 89 %
Q9UEE5 BXGT021671 Serine/threonine-protein kinase 17A reviewed Kinase STK17A Residual Activity '=' 6 %
P08581 BXGT006794 Hepatocyte growth factor receptor reviewed Kinase MET Residual Activity '=' 75 %
P49137 BXGT010680 MAP kinase-activated protein kinase 2 reviewed Kinase MAPKAPK2 Residual Activity '=' 79 %
Q15078 BXGT013534 Cyclin-dependent kinase 5 activator 1 reviewed Enzyme modulator CDK5R1 Residual Activity '=' 9 %
Q00535 BXGT012534 Cyclin-dependent-like kinase 5 reviewed Kinase CDK5 Residual Activity '=' 9 %
P54753 BXGT011073 Ephrin type-B receptor 3 reviewed Kinase EPHB3 Residual Activity '=' 81 %
Q16288 BXGT013625 NT-3 growth factor receptor reviewed Kinase NTRK3 Ki '=' 7 nM
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 199 nM
P53778 BXGT011013 Mitogen-activated protein kinase 12 reviewed Kinase MAPK12 Ki '>' 6309 nM
P05129 BXGT006322 Protein kinase C gamma type reviewed Kinase PRKCG Ki '=' 316 nM
Q05655 BXGT012832 Protein kinase C delta type reviewed Kinase PRKCD Residual Activity '=' 99 %
P78362 BXGT011839 SRSF protein kinase 2 reviewed Kinase SRPK2 Residual Activity '=' 57 %
P52333 BXGT010928 Tyrosine-protein kinase JAK3 reviewed Kinase JAK3 IC50 '=' 957 nM
Q08881 BXGT013012 Tyrosine-protein kinase ITK/TSK reviewed Kinase ITK Residual Activity '=' 21 %
P09769 BXGT006917 Tyrosine-protein kinase Fgr reviewed Kinase FGR Residual Activity '=' 75 %
P52333 BXGT010928 Tyrosine-protein kinase JAK3 reviewed Kinase JAK3 Residual Activity '=' 9 %
Q13557 BXGT013376 Calcium/calmodulin-dependent protein kinase type II subunit delta reviewed Kinase CAMK2D Residual Activity '=' 8 %
P23443 BXGT008866 Ribosomal protein S6 kinase beta-1 reviewed Kinase RPS6KB1 Residual Activity '=' 14 %
Q9P286 BXGT021299 Serine/threonine-protein kinase PAK 5 reviewed Kinase PAK5 Residual Activity '=' 99 %
P53778 BXGT011013 Mitogen-activated protein kinase 12 reviewed Kinase MAPK12 Residual Activity '=' 61 %
P53779 BXGT011014 Mitogen-activated protein kinase 10 reviewed Kinase MAPK10 Inhibition - - -
P08659 BXGT006805 Luciferin 4-monooxygenase reviewed - Potency - 28695 nM
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 reviewed Kinase KDR Ki '=' 630 nM
Q9NYL2 BXGT021259 Mitogen-activated protein kinase kinase kinase 20 reviewed Kinase MAP3K20 Ki '=' 501 nM
Q8TDX7 BXGT018817 Serine/threonine-protein kinase Nek7 reviewed Kinase NEK7 Residual Activity '=' 99 %
O15530 BXGT004177 3-phosphoinositide-dependent protein kinase 1 reviewed Kinase PDPK1 Activity '=' 56 %
Q14012 BXGT013437 Calcium/calmodulin-dependent protein kinase type 1 reviewed Kinase CAMK1 Ki '>' 1584 nM
P08069 BXGT006723 Insulin-like growth factor 1 receptor reviewed Kinase IGF1R Ki '>' 1995 nM
P00519 BXGT005570 Tyrosine-protein kinase ABL1 reviewed Kinase ABL1 Ki '>' 630 nM
P30530 BXGT009431 Tyrosine-protein kinase receptor UFO reviewed Kinase AXL Residual Activity '=' 17 %
P08631 BXGT006801 Tyrosine-protein kinase HCK reviewed Kinase HCK Residual Activity '=' 83 %
P19784 BXGT008513 Casein kinase II subunit alpha' reviewed Kinase CSNK2A2 Residual Activity '=' 59 %
P49760 BXGT010735 Dual specificity protein kinase CLK2 reviewed Kinase CLK2 Ki '=' 630 nM
Q00526 BXGT012531 Cyclin-dependent kinase 3 reviewed Kinase CDK3 Residual Activity '=' 14 %
O96020 BXGT005416 G1/S-specific cyclin-E2 reviewed Enzyme modulator CCNE2 Residual Activity '=' 14 %
P24864 BXGT009000 G1/S-specific cyclin-E1 reviewed Enzyme modulator CCNE1 Residual Activity '=' 14 %
P45983 BXGT010494 Mitogen-activated protein kinase 8 reviewed Kinase MAPK8 Ki '=' 125 nM
P49841 BXGT010750 Glycogen synthase kinase-3 beta reviewed Kinase GSK3B Ki '=' 316 nM
P29323 BXGT009334 Ephrin type-B receptor 2 reviewed Kinase EPHB2 Residual Activity '=' 95 %
P54753 BXGT011073 Ephrin type-B receptor 3 reviewed Kinase EPHB3 Residual Activity '=' 111 %
O43293 BXGT004584 Death-associated protein kinase 3 reviewed Kinase DAPK3 Residual Activity '=' 45 %
P51955 BXGT010908 Serine/threonine-protein kinase Nek2 reviewed Kinase NEK2 Residual Activity '=' 86 %
Q06418 BXGT012875 Tyrosine-protein kinase receptor TYRO3 reviewed Kinase TYRO3 Residual Activity '=' 81 %
P78396 BXGT011842 Cyclin-A1 reviewed Enzyme modulator CCNA1 Residual Activity '=' 59 %
P20248 BXGT008554 Cyclin-A2 reviewed Enzyme modulator CCNA2 Residual Activity '=' 59 %
P24941 BXGT009002 Cyclin-dependent kinase 2 reviewed Kinase CDK2 Residual Activity '=' 59 %
P45984 BXGT010495 Mitogen-activated protein kinase 9 reviewed Kinase MAPK9 Residual Activity '=' -6 %
P49840 BXGT010749 Glycogen synthase kinase-3 alpha reviewed Kinase GSK3A Residual Activity '=' 54 %
Q9UEE5 BXGT021671 Serine/threonine-protein kinase 17A reviewed Kinase STK17A Ki '=' 39 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 20596 nM
P42684 BXGT010331 Tyrosine-protein kinase ABL2 reviewed Kinase ABL2 Kd - - -
P10721 BXGT007605 Mast/stem cell growth factor receptor Kit reviewed Kinase KIT Ki '=' 1258 nM
Q16513 BXGT013632 Serine/threonine-protein kinase N2 reviewed Kinase PKN2 Residual Activity '=' 32 %
Q96GD4 BXGT019667 Aurora kinase B reviewed Kinase AURKB Inhibition - - -
P42681 BXGT010330 Tyrosine-protein kinase TXK reviewed Kinase TXK Residual Activity '=' 23 %
Q04912 BXGT012790 Macrophage-stimulating protein receptor reviewed Kinase MST1R Residual Activity '=' 78 %
P51451 BXGT010848 Tyrosine-protein kinase Blk reviewed Kinase BLK Residual Activity '=' 45 %
Q00534 BXGT012533 Cyclin-dependent kinase 6 reviewed Kinase CDK6 Residual Activity '=' 31 %
P30281 BXGT009416 G1/S-specific cyclin-D3 reviewed Enzyme modulator CCND3 Residual Activity '=' 31 %
P57059 BXGT011210 Serine/threonine-protein kinase SIK1 reviewed - SIK1 Residual Activity '=' 48 %
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase reviewed - APEX1 Potency - 31622 nM
Q99700 BXGT019949 Ataxin-2 reviewed Nucleic acid binding ATXN2 Potency - 25118 nM
O43293 BXGT004584 Death-associated protein kinase 3 reviewed Kinase DAPK3 Inhibition - - -
Q05513 BXGT012820 Protein kinase C zeta type reviewed Kinase PRKCZ Residual Activity '=' 110 %
P41743 BXGT010270 Protein kinase C iota type reviewed Kinase PRKCI Ki '>' 5011 nM
O96017 BXGT005415 Serine/threonine-protein kinase Chk2 reviewed Kinase CHEK2 Residual Activity '=' 2 %
P29320 BXGT009332 Ephrin type-A receptor 3 reviewed Kinase EPHA3 Residual Activity '=' 48 %
Q9H4B4 BXGT020474 Serine/threonine-protein kinase PLK3 reviewed Kinase PLK3 Residual Activity '=' 94 %
P14616 BXGT008026 Insulin receptor-related protein reviewed Kinase INSRR Residual Activity '=' 51 %
Q9NWZ3 BXGT021239 Interleukin-1 receptor-associated kinase 4 reviewed Kinase IRAK4 Residual Activity '=' 36 %
Q9HBY8 BXGT020524 Serine/threonine-protein kinase Sgk2 reviewed Kinase SGK2 Residual Activity '=' 71 %
P51817 BXGT010895 cAMP-dependent protein kinase catalytic subunit PRKX reviewed Kinase PRKX Residual Activity '=' 86 %
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase reviewed - APEX1 Potency - 35481 nM
O14924 BXGT004111 Regulator of G-protein signaling 12 reviewed - RGS12 Potency '=' 25118 nM
P63096 BXGT011496 Guanine nucleotide-binding protein G(i) subunit alpha-1 reviewed Enzyme modulator GNAI1 Potency '=' 25118 nM
Q9P286 BXGT021299 Serine/threonine-protein kinase PAK 5 reviewed Kinase PAK5 Residual Activity '=' 64 %
P07332 BXGT006601 Tyrosine-protein kinase Fes/Fps reviewed Kinase FES Residual Activity '=' 6 %
Q9HBH9 BXGT020521 MAP kinase-interacting serine/threonine-protein kinase 2 reviewed Kinase MKNK2 Residual Activity '=' 10 %
P28482 BXGT009263 Mitogen-activated protein kinase 1 reviewed Kinase MAPK1 Residual Activity '=' 88 %
P53779 BXGT011014 Mitogen-activated protein kinase 10 reviewed Kinase MAPK10 IC50 '=' 10000 nM
Q8N568 BXGT018516 Serine/threonine-protein kinase DCLK2 reviewed Kinase DCLK2 Residual Activity '=' 51 %
P34947 BXGT009774 G protein-coupled receptor kinase 5 reviewed Kinase GRK5 Residual Activity '=' 84 %
Q7KZI7 BXGT016990 Serine/threonine-protein kinase MARK2 reviewed Kinase MARK2 Residual Activity '=' 12 %
Q9HCP0 BXGT020536 Casein kinase I isoform gamma-1 reviewed Kinase CSNK1G1 Residual Activity '=' 99 %
O43353 BXGT004589 Receptor-interacting serine/threonine-protein kinase 2 reviewed Kinase RIPK2 Residual Activity '=' 52 %
P36896 BXGT009940 Activin receptor type-1B reviewed Kinase ACVR1B Residual Activity '=' 86 %
P53355 BXGT010985 Death-associated protein kinase 1 reviewed Kinase DAPK1 Residual Activity '=' 91 %
O96017 BXGT005415 Serine/threonine-protein kinase Chk2 reviewed Kinase CHEK2 Ki '=' 501 nM
Q7L7X3 BXGT016997 Serine/threonine-protein kinase TAO1 reviewed Kinase TAOK1 Ki '=' 5011 nM
Q9H2X6 BXGT020458 Homeodomain-interacting protein kinase 2 reviewed Kinase HIPK2 Residual Activity '=' 55 %
P08922 BXGT006843 Proto-oncogene tyrosine-protein kinase ROS reviewed Kinase ROS1 Residual Activity '=' 85 %
P51451 BXGT010848 Tyrosine-protein kinase Blk reviewed Kinase BLK Residual Activity '=' 97 %
Q9Y243 BXGT022214 RAC-gamma serine/threonine-protein kinase reviewed Kinase AKT3 Residual Activity '=' 89 %
Q8IYT8 BXGT018370 Serine/threonine-protein kinase ULK2 reviewed Kinase ULK2 Residual Activity '=' 45 %
P00533 BXGT005575 Epidermal growth factor receptor reviewed Kinase EGFR Residual Activity '=' 121 %
O75676 BXGT005144 Ribosomal protein S6 kinase alpha-4 reviewed Kinase RPS6KA4 Residual Activity '=' 76 %
P00533 BXGT005575 Epidermal growth factor receptor reviewed Kinase EGFR Residual Activity '=' 112 %
P51813 BXGT010894 Cytoplasmic tyrosine-protein kinase BMX reviewed Kinase BMX Residual Activity '=' 59 %
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF05043 mammea siamensis mammea siamensis Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease