Showing entry for Mas-related G-protein coupled receptor member X2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019692
Protein NameMas-related G-protein coupled receptor member X2
Uniport IdQ96LB1
GeneMRGPRX2
Gene Id117194
Domain7tm_1
Pfam PF00001  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007186 G protein-coupled receptor signaling pathway
Biological Process GO:0045576 mast cell activation
Biological Process GO:0043303 mast cell degranulation
Biological Process GO:0032467 positive regulation of cytokinesis
Biological Process GO:0019233 sensory perception of pain
Biological Process GO:0030431 sleep
molecular function GO:0004930 G protein-coupled receptor activity
molecular function GO:1990595 mast cell secretagogue receptor activity
molecular function GO:0042923 neuropeptide binding
cellular component GO:0016021 integral component of membrane
cellular component GO:0042629 mast cell granule
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002792 BXGD000129 anaphylaxis Immune System Diseases
C0002873 BXGD000133 Anemia of chronic disease Hemic and Lymphatic Diseases
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004623 BXGD000282 Bacterial Infections Infections
C0011603 BXGD000734 Dermatitis Skin and Connective Tissue Diseases
C0011616 BXGD000739 Contact Dermatitis Skin and Connective Tissue Diseases
C0022104 BXGD001529 Irritable Bowel Syndrome Digestive System Diseases
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0031090 BXGD002280 Periodontal Diseases Stomatognathic Diseases
C0031099 BXGD002282 Periodontitis Stomatognathic Diseases
C0035854 BXGD002568 Rosacea Skin and Connective Tissue Diseases
C0221292 BXGD004440 Basophilic leukemia Neoplasms
C0263338 BXGD005290 Chronic urticaria Skin and Connective Tissue Diseases; Immune System Diseases
C0266929 BXGD005722 Chronic Periodontitis Stomatognathic Diseases
C0278134 BXGD006498 Absence of sensation Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C1275685 BXGD012092 Avellino corneal dystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C1306792 BXGD012376 Red man syndrome Pathological Conditions, Signs and Symptoms; Skin and Connective Tissue Diseases
C2607914 BXGD017148 Allergic rhinitis (disorder) Respiratory Tract Diseases; Immune System Diseases; Otorhinolaryngologic Diseases
C4554601 BXGD023566 Amyloidosis cutis dyschromia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0005870 Codeine 299.36
BXGC0014545 Hydrocodone 299.15
BXGC0020308 norcodeine 285.14
BXGC0023527 Thebaine 311.15
BXGC0030901 Morphine 285.14
BXGC0035009 Isocodeine 299.15
BXGC0035676 morphine-3-glucuronide 461.17
BXGC0039964 (+)-morphine 285.14
BXGC0044167 6-O-monoacetylmorphine 327.15
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein