adisease

Showing entry for anaphylaxis

General Disease Information
BXGD Id	BXGD000129
Disease Name	anaphylaxis
Disease CUI Id	C0002792
MeSH Codes	C20
Disease Class Name	Immune System Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0002715
Human Phenotype Ontology Term	Abnormality of the immune system
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00187	BXGT003890	Mannan-binding lectin serine protease 2	10747	reviewed	Enzyme
O14672	BXGT004081	Disintegrin and metalloproteinase domain-containing protein 10	102	reviewed
O15067	BXGT004123	Phosphoribosylformylglycinamidine synthase	5198	reviewed
O15379	BXGT004159	Histone deacetylase 3	8841	reviewed	Epigenetic regulator
O60885	BXGT004906	Bromodomain-containing protein 4	23476	reviewed	Epigenetic regulator
O75015	BXGT005095	Low affinity immunoglobulin gamma Fc region receptor III-B	2215	reviewed	Cell adhesion
O75030	BXGT005096	Microphthalmia-associated transcription factor	4286	reviewed
P00451	BXGT005545	Coagulation factor VIII	2157	reviewed	Enzyme
P00519	BXGT005570	Tyrosine-protein kinase ABL1	25	reviewed	Kinase
P00740	BXGT005634	Coagulation factor IX	2158	reviewed	Enzyme
P00742	BXGT005636	Coagulation factor X	2159	reviewed	Enzyme
P01019	BXGT005717	Angiotensinogen	183	reviewed	Enzyme modulator
P01042	BXGT005722	Kininogen-1	3827	reviewed	Enzyme modulator
P01275	BXGT005747	Glucagon	2641	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01589	BXGT005773	Interleukin-2 receptor subunit alpha	3559	reviewed	Receptor
P01920	BXGT005817	HLA class II histocompatibility antigen, DQ beta 1 chain	3119	reviewed	Immune response
P02647	BXGT005908	Apolipoprotein A-I	335	reviewed
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P04070	BXGT006143	Vitamin K-dependent protein C	5624	reviewed	Enzyme
P04275	BXGT006180	von Willebrand factor	7450	reviewed	Enzyme modulator
P04406	BXGT006207	Glyceraldehyde-3-phosphate dehydrogenase	2597	reviewed	Enzyme
P05164	BXGT006333	Myeloperoxidase	4353	reviewed	Enzyme
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P06850	BXGT006511	Corticoliberin	1392	reviewed	Signaling
P07339	BXGT006604	Cathepsin D	1509	reviewed	Enzyme
P07550	BXGT006636	Beta-2 adrenergic receptor	154	reviewed	G-protein coupled receptor
P08588	BXGT006795	Beta-1 adrenergic receptor	153	reviewed	G-protein coupled receptor
P08637	BXGT006802	Low affinity immunoglobulin gamma Fc region receptor III-A	2214	reviewed	Cell adhesion
P09466	BXGT006892	Glycodelin	5047	reviewed	Enzyme
P10147	BXGT007543	C-C motif chemokine 3	6348	reviewed	Signaling
P10721	BXGT007605	Mast/stem cell growth factor receptor Kit	3815	reviewed	Kinase
P12314	BXGT007798	High affinity immunoglobulin gamma Fc receptor I	2209	reviewed	Cell adhesion
P12318	BXGT007799	Low affinity immunoglobulin gamma Fc region receptor II-a	2212	reviewed	Cell adhesion
P12319	BXGT007800	High affinity immunoglobulin epsilon receptor subunit alpha	2205	reviewed	Cell adhesion
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P15169	BXGT008093	Carboxypeptidase N catalytic chain	1369	reviewed
P15289	BXGT008102	Arylsulfatase A	410	reviewed	Enzyme
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P16442	BXGT008227	Histo-blood group ABO system transferase	28	reviewed	Enzyme
P16671	BXGT008255	Platelet glycoprotein 4	948	reviewed	Receptor
P18031	BXGT008369	Tyrosine-protein phosphatase non-receptor type 1	5770	reviewed
P19113	BXGT008458	Histidine decarboxylase	3067	reviewed
P19320	BXGT008470	Vascular cell adhesion protein 1	7412	reviewed
P19838	BXGT008526	Nuclear factor NF-kappa-B p105 subunit	4790	reviewed	Transcription factor
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	1131	reviewed	G-protein coupled receptor
P20472	BXGT008578	Parvalbumin alpha	5816	reviewed	Calcium-binding protein
P20930	BXGT008616	Filaggrin	2312	reviewed	Cellular structure
P21549	BXGT008661	Serine--pyruvate aminotransferase	189	reviewed	Enzyme
P22736	BXGT008800	Nuclear receptor subfamily 4 group A member 1	3164	reviewed	Nuclear receptor
P22897	BXGT008816	Macrophage mannose receptor 1	4360	reviewed
P23219	BXGT008837	Prostaglandin G/H synthase 1	5742	reviewed	Enzyme
P24298	BXGT008960	Alanine aminotransferase 1	2875	reviewed	Enzyme
P24855	BXGT008998	Deoxyribonuclease-1	1773	reviewed
P25105	BXGT009021	Platelet-activating factor receptor	5724	reviewed	G-protein coupled receptor
P29350	BXGT009335	Tyrosine-protein phosphatase non-receptor type 6	5777	reviewed
P29474	BXGT009352	Nitric oxide synthase, endothelial	4846	reviewed
P30536	BXGT009435	Translocator protein	706	reviewed
P33681	BXGT009739	T-lymphocyte activation antigen CD80	941	reviewed
P34932	BXGT009772	Heat shock 70 kDa protein 4	3308	reviewed
P34998	BXGT009781	Corticotropin-releasing factor receptor 1	1394	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35869	BXGT009877	Aryl hydrocarbon receptor	196	reviewed	Transcription factor
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P42226	BXGT010288	Signal transducer and activator of transcription 6	6778	reviewed	Nucleic acid binding
P46098	BXGT010507	5-hydroxytryptamine receptor 3A	3359	reviewed	Ion channel
P46531	BXGT010526	Neurogenic locus notch homolog protein 1	4851	reviewed
P48023	BXGT010604	Tumor necrosis factor ligand superfamily member 6	356	reviewed	Signaling
P50591	BXGT010814	Tumor necrosis factor ligand superfamily member 10	8743	reviewed	Signaling
P53985	BXGT011022	Monocarboxylate transporter 1	6566	reviewed	Transporter
P55157	BXGT011108	Microsomal triglyceride transfer protein large subunit	4547	reviewed	Transporter
P61626	BXGT011382	Lysozyme C	4069	reviewed
P78504	BXGT011844	Protein jagged-1	182	reviewed
Q06187	BXGT012860	Tyrosine-protein kinase BTK	695	reviewed	Kinase
Q14032	BXGT013438	Bile acid-CoA:amino acid N-acyltransferase	570	reviewed
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q14524	BXGT013478	Sodium channel protein type 5 subunit alpha	6331	reviewed	Ion channel
Q15389	BXGT013564	Angiopoietin-1	284	reviewed	Signaling
Q15722	BXGT013590	Leukotriene B4 receptor 1	1241	reviewed	G-protein coupled receptor
Q15831	BXGT013604	Serine/threonine-protein kinase STK11	6794	reviewed	Kinase
Q15833	BXGT013605	Syntaxin-binding protein 2	6813	reviewed	Transporter
Q16873	BXGT013684	Leukotriene C4 synthase	4056	reviewed	Enzyme
Q5Y7D3	BXGT015912	HLA class II histocompatibility antigen DQ beta chain	3119	unreviewed
Q8IVS2	BXGT018349	Malonyl-CoA-acyl carrier protein transacylase, mitochondrial	27349	reviewed
Q8NEM0	BXGT018555	Microcephalin	79648	reviewed	Nucleic acid binding
Q8NER1	BXGT018556	Transient receptor potential cation channel subfamily V member 1	7442	reviewed	Ion channel
Q92731	BXGT019366	Estrogen receptor beta	2100	reviewed	Nuclear receptor
Q96AZ6	BXGT019621	Interferon-stimulated gene 20 kDa protein	3669	reviewed
Q96EB6	BXGT019646	NAD-dependent protein deacetylase sirtuin-1	23411	reviewed	Epigenetic regulator
Q96LB1	BXGT019692	Mas-related G-protein coupled receptor member X2	117194	reviewed	G-protein coupled receptor
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q96RI1	BXGT019727	Bile acid receptor	9971	reviewed	Nuclear receptor
Q9BX66	BXGT020158	Sorbin and SH3 domain-containing protein 1	10580	reviewed
Q9H0P0	BXGT020439	Cytosolic 5'-nucleotidase 3A	51251	reviewed	Enzyme
Q9UI42	BXGT021713	Carboxypeptidase A4	51200	reviewed	Enzyme
Q9UIQ6	BXGT021721	Leucyl-cystinyl aminopeptidase	4012	reviewed	Enzyme
P00738	BXGT022874	Haptoglobin	3240	reviewed	Enzyme
P16284	BXGT022972	Platelet endothelial cell adhesion molecule	5175	reviewed	Cell adhesion
P31994	BXGT023298	Low affinity immunoglobulin gamma Fc region receptor II-b	2213	reviewed	Cell adhesion
O60502	BXGT023392	Protein O-GlcNAcase	10724	reviewed
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
A9YTQ3	BXGT023537	Aryl hydrocarbon receptor repressor	57491	reviewed	Transcription factor
P20138	BXGT023857	Myeloid cell surface antigen CD33	945	reviewed	Receptor

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}